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PODCAST

Extend Podcast with Darshan Shah, MD

Darshan Shah, MD

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health

health & fitness medicine

All Episodes

01:31:50

71. Dr. Michael Breus: Why “Feeling Fine” Doesn’t...

Extend Podcast with Darshan Shah, MD ·

2025/06/17

What if your exhaustion, brain fog, or cravings aren’t a motivation problem—but a sleep problem no one’s diagnosed yet? In this episode of Extend, I’m joined by Dr. Michael Breuss, a sleep specialist, and we dig into why so many high performers are chronically under-recovered, why sleep disorders go undetected for years, and how wearables are both helping and hurting. We talk about why 8 hours might be the wrong goal, how your chronotype should determine your schedule, why snoring isn’t harmless,

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46:08

70. Kelly Gores: Why Most People Stay Sick (And How...

Extend Podcast with Darshan Shah, MD ·

2025/06/12

Most people focus on physical health. But after years of practicing medicine, I’ve seen this truth again and again: you can’t heal your body if your mind and nervous system are stuck in survival mode. In this episode of Extend, I sat down with Kelly Gores, creator of HEAL and founder of WellSet, to explore how trauma, stress, and emotional blocks drive chronic disease—and what it really takes to heal. We dive into the science behind the placebo effect, how intuition works, why regulating your

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01:07:34

69. Dr. Kara Fitzgerald: This Hack Reversed...

Extend Podcast with Darshan Shah, MD ·

2025/06/10

What if aging isn’t just inevitable—but programmable? In this episode of Extend, I sit down with Dr. Kara Fitzgerald, pioneering epigenetic researcher and author of Younger You, to explore how your daily choices—food, movement, sleep, stress—can literally rewire your genes to slow down aging. We unpack her groundbreaking study showing biological age reversal in just 8 weeks without drugs, injections, or extreme protocols. You’ll learn how DNA methylation impacts everything from inflammation to

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35:29

68. Jen Batchelor: The Real Reason You’re Burned Out...

Extend Podcast with Darshan Shah, MD ·

2025/06/05

Most people are treating stress with the wrong tools, and it’s silently sabotaging their longevity. In this episode of Extend, I sit down with Jen Batchelor, Ayurvedic health optimizer and co-founder of Kin Euphorics, to talk about what your nervous system actually needs to feel calm, connected, and well. We dive into what adaptogens are really doing in your body, why saffron might be one of the most powerful neuroprotective tools available, and how homeostasis—not hustle—is the key to better energy

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01:48:13

67. Chris Mirabile: How to Reverse Your Biological...

Extend Podcast with Darshan Shah, MD ·

2025/06/03

What if your real age isn’t on your driver’s license—but buried in your biology? In this episode of Extend, I’m joined by Chris Mirabile, founder of NOVOS and one of the few people actually slowing down his pace of aging. We break down why the average person is aging faster than they realize, and how mainstream medicine is decades behind when it comes to prevention. We get into the 12 hallmarks of aging, why free radicals aren’t your enemy, how biological clocks really work, and the lifestyle and

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01:06:45

66. Steve Martocci: Inside the $50B Supplement Scam,...

Extend Podcast with Darshan Shah, MD ·

2025/05/29

Most supplements don’t work. Some might actually harm you. That’s the hard truth no one in the $50 billion supplement industry wants to say out loud—but we will. In today’s episode of Extend, I’m joined by Steve Martocci, co-founder of SuppCo, to expose what’s really going on behind the labels. We break down why “clinically dosed” means nothing, why the FDA isn’t protecting you, and how two identical bottles can deliver completely different outcomes. We also dive into the myth of “FDA-approved”

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01:55:17

65. Dr. Austin Perlmutter: Why You’re Addicted to Bad...

Extend Podcast with Darshan Shah, MD ·

2025/05/27

What if the reason you can’t focus, feel chronically overwhelmed, or keep slipping into the same unhealthy habits… isn’t a discipline problem, it's your brain’s biology working against you? In this episode of Extend, I'm joined by Dr. Austin Perlmutter, board-certified internal medicine physician and neuroscientist, to explore how inflammation hijacks your brain’s decision-making and what you can do to take back control. We dig into why modern life wires your brain for reactivity over intention, the

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18:16

64. LP(a): The Massively Important, But Totally...

Extend Podcast with Darshan Shah, MD ·

2025/05/22

In this episode of Extend, we’re digging into one of the most dangerous—and most overlooked—drivers of heart disease: LP(a). You could have a clean lifestyle, normal labs, and still be at high risk for a heart attack or stroke. Why? Because LP(a) isn’t included in standard cholesterol tests—and 1 in 5 people have elevated levels without knowing it. I break down what LP(a) actually is, why it’s more inflammatory and damaging than LDL, and how it contributes to plaque, heart attacks, strokes, and

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01:11:56

63. Charles Brenner: NAD, Energy, and Longevity: The...

Extend Podcast with Darshan Shah, MD ·

2025/05/20

What if the reason you're tired, inflamed, or not recovering the way you used to has nothing to do with aging, and everything to do with your NAD system being under attack? In this episode of Extend, I’m joined by Dr. Charles Brenner, the scientist who discovered nicotinamide riboside (NR) and one of the leading experts on NAD metabolism. We unpack why NAD is so critical for energy, repair, and resilience, and why simply “taking NAD” isn’t the solution most people think it is. We also break down the

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34:27

62. David Nurse: How to Rewire Your Brain for Success...

Extend Podcast with Darshan Shah, MD ·

2025/05/15

Most people know mindset matters, but almost no one knows how to actually train it for better health, performance, and longevity. In today's episode of Extend, I'm joined by David Nurse, NBA mindset coach and best-selling author. We dive deep into why mindset is the real missing piece in most health optimization plans, and how flow states, identity shifts, and daily systems can radically change your outcomes. We also break down why your mindset is the ignition switch for success, how to tap into

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01:39:51

61. Dr. Aly Cohen: The #1 Detox Mistake You’re...

Extend Podcast with Darshan Shah, MD ·

2025/05/13

What if the hidden toxins in your everyday life are secretly sabotaging your health, hormones, and longevity? Most people underestimate how deeply their health is impacted by toxins—and conventional medicine isn’t addressing the root of the issue. In this episode of Extend, I'm joined by Dr. Aly Cohen, renowned integrative rheumatologist, environmental health expert, and author of the upcoming book, Detoxify. We uncover the shocking truth about the tens of thousands of unregulated chemicals lurking

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19:24

60. Cholesterol Myths You Still Believe (And What to...

Extend Podcast with Darshan Shah, MD ·

2025/05/08

In this episode of Extend, we’re rethinking everything you’ve been told about cholesterol. For decades, the focus has been on lowering LDL, but that’s only part of the story. The truth? LDL and total cholesterol are outdated metrics. If you're still relying on those alone to assess your heart health, you’re missing the bigger picture. I’ll break down why ApoB is the single most important number to track when it comes to cardiovascular disease, and how it gives a much clearer view of your real risk

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01:20:50

59. Joel Greene: The Nutrition Secret That Reverses...

Extend Podcast with Darshan Shah, MD ·

2025/05/06

What if the secret to better energy, fat loss, and gut health wasn’t more discipline… but a smarter strategy? Most people are hacking the wrong system—and it’s backfiring. In this episode of Extend, I’m joined by Joel Greene, creator of the VEEP Nutrition System and one of the most innovative minds in metabolic health. We break down the science behind fat loss, blood sugar regulation, gut health, and why conventional diet advice is failing most people. We dive into how your microbiome controls

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40:27

58. Ricky Silver: What the Food Companies Don’t Want...

Extend Podcast with Darshan Shah, MD ·

2025/05/01

What if our food system wasn’t designed for our health, but for shelf life, convenience, and corporate profit? In today’s episode of Extend, I’m joined by Ricky Silver, CEO of Daily Harvest, who brings a rare inside-the-industry view of how our food system really works, and how we can change it. We explore how government subsidies, processed foods, and industrial farming practices have led to the chronic disease crisis we’re facing today. We dig into why frozen organic produce is a nutritional

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01:42:42

57. Shawn Wells: Shocking Truth About Supplements:...

Extend Podcast with Darshan Shah, MD ·

2025/04/29

What if the reason your supplements aren’t working has nothing to do with your body—and everything to do with what’s in the bottle? In this episode of Extend, I’m joined by biochemist and ingredient formulator Shawn Wells, a leading voice in evidence-based supplementation and mitochondrial health. Together, we uncover why so many products fail to deliver results, how to build a smarter, personalized stack, and what most people get completely wrong about vitamins, probiotics, and biohacking. We get

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30:57

56. Zora Benhamou: Struggling with Menopause? Here’s...

Extend Podcast with Darshan Shah, MD ·

2025/04/24

What if menopause didn’t have to be a challenge, but an opportunity? In this episode of Extend, I’m joined by Zora Benhamou, host of the Hack My Age podcast, to challenge the common narrative around menopause. Zora shares a refreshing perspective that empowers women to see this stage of life as a chance for reinvention, growth, and better health. We discuss the science behind hormone therapy, the importance of muscle-building and stress management, and how women can navigate menopause without

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01:27:56

55. Jim Kwik: The Real Reason You're Tired,...

Extend Podcast with Darshan Shah, MD ·

2025/04/22

Brain fog, forgetfulness, and lack of focus are becoming the norm, but they don’t have to be. In this episode of Extend, I’m joined by Jim Kwik, a world-renowned brain coach and author of the bestselling book Limitless, to uncover how to unlock your brain’s full potential. We dive into the science of neuroplasticity, daily habits that sabotage your memory, and how to reclaim focus in a world of constant distraction. Jim shares actionable tools to improve learning, strengthen cognitive performance,

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12:37

54. What If High Blood Pressure Is Slowly Killing You?

Extend Podcast with Darshan Shah, MD ·

2025/04/17

In today’s episode of Extend, we’re tackling a crucial health issue: high blood pressure. Often called the "silent killer," high blood pressure increases your risk for heart attacks, strokes, kidney disease, and more. But what if you could prevent these risks before they escalate? I’ll break down why measuring your blood pressure at home is far more effective than relying on a single doctor’s visit. You’ll also learn about the SPRINT trial and why keeping your blood pressure at 120/70 can

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01:00:28

53. Dr. Alok Trivedi: You’re Not Lazy—You’re Wired...

Extend Podcast with Darshan Shah, MD ·

2025/04/15

Ever feel stuck, even when you're doing all the right things? In this episode, Dr. Shah sits down with Dr. Alok Trivedi, also known as Dr. Rewire, to explore how our unresolved traumas, subconscious beliefs, and identity patterns silently shape our health, habits, and happiness. You’ll discover how trauma wires into the nervous system, why mindset work often fails without deeper emotional integration, and how behavioral reprogramming can unlock personal and professional breakthroughs. Dr. Trivedi

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47:53

52. Dr. Greg Kelly: Stop Wasting Money on...

Extend Podcast with Darshan Shah, MD ·

2025/04/10

With shelves full of flashy promises, it’s time to cut through the noise. In this episode, Dr. Shah and Dr. Greg Kelly explore what science actually says about supplements—and what your body truly needs to perform at its best. You’ll learn how nootropics, adaptogens, and probiotics influence brain health, stress resilience, and longevity. Backed by clinical research, Dr. Kelly unpacks the key mechanisms behind compounds that support cognitive performance, neuroplasticity, and the gut-brain

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132 results

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