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PODCAST

Extend Podcast with Darshan Shah, MD

Darshan Shah, MD

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health

health & fitness medicine

All Episodes

01:01:54

158. Dr. Kavin Mistry: Primal Health Design,...

Extend Podcast with Darshan Shah, MD ·

2026/04/23

Modern life is quietly accelerating biological aging, from posture and movement patterns to sleep disruption, chronic stress, and constant digital stimulation. Many of the symptoms people experience daily, like pain, fatigue, brain fog, and disconnection, may reflect a deeper misalignment with how the human body was designed to function. In this episode of Extend, I sit down with Dr. Kavin Mistry, board-certified neuroradiologist and author of Primal Health Design, to unpack how modern lifestyles

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01:03:53

157. Dr. Tania Elliott: Allergies, Immune Health, and...

Extend Podcast with Darshan Shah, MD ·

2026/04/21

Allergies, chronic inflammation, and constant exposure to environmental toxins are reshaping how our immune system functions, often in ways that go unnoticed until symptoms appear. What many people see as isolated issues like gut problems, skin reactions, or fatigue may actually reflect a deeper immune imbalance. In this episode of Extend, I sit down with Dr. Tania Elliott, double board-certified physician in internal medicine and allergy and immunology, to unpack how the immune system operates

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42:08

156. Dr. Judith Joseph: High-Functioning Depression,...

Extend Podcast with Darshan Shah, MD ·

2026/04/16

High-performing individuals often appear successful on the outside while quietly experiencing a loss of joy, emotional numbness, and chronic internal stress. This disconnect, often overlooked in traditional diagnostics, may signal a form of depression that goes unrecognized for years. In this episode of Extend, we sit down with Dr. Judith Joseph, psychiatrist, researcher, and author of High Functioning, to unpack the science of high-functioning depression and how anhedonia can manifest even in

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55:24

155. Dr. Eboni Cornish: Neural Longevity, Brain...

Extend Podcast with Darshan Shah, MD ·

2026/04/14

Cognitive decline, mood disorders, and persistent neurological symptoms are often treated in isolation, even as underlying drivers like inflammation, infections, and blood flow dysfunction continue to go unaddressed. Emerging research suggests that brain health requires a root cause approach that integrates physiology, environment, and lifestyle over time. In this episode of Extend, we sit down with Dr. Eboni Cornish, Associate Medical Director at Amen Clinics and President Elect of ILADS, to unpack

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55:54

154. Dr. Rick Doblin - Part 2: Psychedelics, MDMA...

Extend Podcast with Darshan Shah, MD ·

2026/04/09

Mental health conditions like depression, PTSD, and trauma related disorders remain difficult to treat, especially when underlying cognitive and emotional patterns persist over time. Emerging research suggests psychedelic assisted therapies may work by temporarily changing how the brain processes information and the sense of self. In this episode of Extend, we continue our conversation with Dr. Rick Doblin, founder of MAPS, to explore the mechanisms behind psychedelic therapy. We break down how

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01:03:37

153. Dr. Rick Doblin - Part 1: Psychedelics, MDMA...

Extend Podcast with Darshan Shah, MD ·

2026/04/07

Depression, PTSD, and trauma related disorders continue to challenge modern medicine, even as our understanding of the brain and consciousness rapidly evolves. New research suggests that certain therapies may help unlock deeper healing by combining neuroscience, psychology, and carefully guided experiences. In this episode of Extend, we sit down with Dr. Rick Doblin, founder of MAPS, to unpack the science and history behind psychedelic assisted therapy and its potential role in mental health

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01:17:45

152. Nick Norwitz: Cholesterol Myths, Insulin...

Extend Podcast with Darshan Shah, MD ·

2026/04/02

Cholesterol remains one of the most debated biomarkers in cardiovascular medicine, yet many people still misunderstand what it actually tells us about metabolic health and disease risk. As research evolves, the conversation is shifting from simple cholesterol numbers toward deeper drivers of cardiometabolic dysfunction. In this episode of Extend, we sit down with Nick Norwitz, metabolic health researcher and physician scientist, to unpack the science behind cholesterol, insulin resistance, and

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45:13

151. Ramses Alcaide: Brain Wearables, EEG, and the...

Extend Podcast with Darshan Shah, MD ·

2026/03/31

Chronic stress, cognitive overload, and neurodegenerative disease are rising as modern life pushes the brain beyond what it was designed to handle. At the same time, most people still have almost no visibility into how their brain is actually performing day to day. In this episode of Extend, we sit down with Ramses Alcaide, founder and CEO of Neurable, to unpack how brain computer interface technology is moving from research laboratories into everyday wearable devices. We break down how non-invasive

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01:41:17

150. Dr. Terry Grossman: Plasma Exchange,...

Extend Podcast with Darshan Shah, MD ·

2026/03/26

Chronic inflammation, environmental toxins, and metabolic dysfunction continue to accelerate aging and chronic disease across modern populations. Many of the biggest drivers of health decline remain invisible, quietly accumulating in the body for decades before symptoms appear. In this episode of Extend, we sit down with Dr. Terry Grossman, physician, longevity expert, and co author of Transcend and Fantastic Voyage with futurist Ray Kurzweil, to unpack the science behind therapeutic plasma exchange

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45:08

149. Kim Rogers: Parasites, Hidden Infections, and...

Extend Podcast with Darshan Shah, MD ·

2026/03/24

Chronic symptoms often get labeled, managed, and medicated, yet the root cause can remain hidden. Parasites, mold exposure, Lyme disease, and microbial imbalances may quietly disrupt energy, digestion, immunity, and cognitive clarity for years without being recognized. In this episode of Extend, we sit down with Kim Rogers, founder of RogersHood Apothecary and creator of the ParaFy Kit, to unpack the hidden role parasites may play in chronic illness and why this topic remains largely absent from

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01:00:46

148. Fitz Koehler: The Four Pillars of Fitness and...

Extend Podcast with Darshan Shah, MD ·

2026/03/19

Strength is the foundation of longevity. When muscle, cardiovascular fitness, mobility, balance, sleep, and nutrition align, performance improves, metabolism sharpens, and aging becomes something you influence rather than fear. In this episode of Extend, we sit down with Fitz Koehler, founder of Fitzness.com, keynote speaker, race announcer, and five time author, to unpack her Four Pillars of Fitness and the exact formula for sustainable weight loss and long term vitality. We break down the

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56:41

147. Dr. David Luu: How AI Is Reshaping Preventive Care

Extend Podcast with Darshan Shah, MD ·

2026/03/17

Most people think medicine is about treating disease. What if the real future of healthcare is preventing illness and optimizing human potential long before symptoms appear. In this episode of Extend, we sit down with Dr. David Luu, physician, former pediatric cardiac surgeon, and founder of the Longevity Docs movement. Dr. Luu shares his journey from high intensity surgery to longevity medicine, shaped by firsthand exposure to preventable disease, global health missions, and the realization that

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01:07:47

146. Dr. Joel Warsh: Vaccines, Ultra-Processed Foods...

Extend Podcast with Darshan Shah, MD ·

2026/03/12

Raising healthy children today requires more discernment than ever. Between conflicting vaccine guidance, ultra processed food marketing, and the explosion of screen exposure, modern parents are navigating a landscape filled with noise and strong opinions. In this episode of Extend, we sit down with Dr. Joel Warsh, board certified pediatrician and founder of Integrative Pediatrics, to unpack how parents can think critically about vaccine schedules, evaluate medical credentials online, and make

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01:32:11

145. Dr. Dave Rabin: HRV, Vagal Tone, and the Science...

Extend Podcast with Darshan Shah, MD ·

2026/03/10

Chronic stress is quietly reshaping how we think, perform, sleep, and recover. In a world optimized for productivity, we rarely prioritize the one variable that determines long term resilience: recovery. In this episode of Extend, we sit down with Dr. Dave Rabin, neuroscientist, psychiatrist, and co founder of Apollo Neuro, to unpack the science of vagal tone, heart rate variability, and how safety signals in the body drive peak performance and mental health. We break down the difference between

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58:57

144. Dr. Mao Shing Ni: Fertility Optimization, Egg...

Extend Podcast with Darshan Shah, MD ·

2026/03/05

Fertility is declining while menopausal symptoms are appearing earlier. Metabolic dysfunction, chronic stress, and environmental exposures are reshaping reproductive health for both women and men. In this episode of Extend, we sit down with Dr. Mao Shing Ni, co founder of Tao of Wellness and Yo San University of Traditional Chinese Medicine, to unpack how Eastern medicine and modern science can work together to optimize fertility, support egg freezing outcomes, and reframe menopause as a powerful

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51:14

143. The Teen Health Revolution: Raising Resilient...

Extend Podcast with Darshan Shah, MD ·

2026/03/03

Teen mental health is deteriorating in real time, fueled by ultra processed food, chronic stress, and constant screen exposure. The earlier we intervene, the more resilient the biology and brain become. In this episode of Extend, we sit down with Abdullah, Zain, Emaad, and Qasim Ansari, hosts of The Holistic Kids' Show and co authors of The Teen Health Revolution, to unpack how simple lifestyle shifts can radically improve youth mental, metabolic, and emotional health. We break down their REVOLUTION

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01:18:08

142. Dr. Tommy Wood: The Science of Brain Performance...

Extend Podcast with Darshan Shah, MD ·

2026/02/26

Most conversations about brain health focus on intelligence or genetics. True cognitive performance depends on how the brain is trained, supported, and allowed to recover across decades of life. In this episode of Extend, we sit down with Dr. Tommy Wood, neuroscientist and performance expert working at the intersection of elite motorsport and clinical brain research, to uncover how the brain adapts under extreme cognitive demand and how those same principles apply to long term brain health. We break

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01:08:45

141. Dr. Amy Shah: Hormone Havoc, Gut Health, and the...

Extend Podcast with Darshan Shah, MD ·

2026/02/24

Most women are taught to accept fatigue, weight gain, brain fog, and mood changes as a normal part of aging. What if the real issue has been overlooked gut health, muscle loss, and a medical system that failed to prioritize women's hormones. In this episode of Extend, we sit down with Dr. Amy Shah, MD, double board certified physician in internal medicine and immunology, to unpack the powerful connection between the gut microbiome, hormone balance, and long term health. We break down the

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01:27:51

140. Dr. Kelly Casperson: The Hormone Truth About...

Extend Podcast with Darshan Shah, MD ·

2026/02/19

Most women are taught that aging means decline, less energy, less strength, and less desire. What if the real problem has never been age itself, but untreated hormone loss and outdated medical narratives. In this episode of Extend, we sit down with Dr. Kelly Casperson, urologist, hormone expert, and leading voice in women's sexual health, to uncover how hormones shape longevity, muscle, brain health, and quality of life across midlife and beyond. We break down why estrogen, progesterone, and

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01:24:12

139. JJ Virgin: Muscle Over Weight Loss

Extend Podcast with Darshan Shah, MD ·

2026/02/17

Most people are told to lose weight to get healthy. What if that mindset is the reason metabolic health keeps getting worse, muscle keeps disappearing, and fat loss never lasts. In this episode of Extend, we sit down with JJ Virgin, triple board certified nutrition expert and Fitness Hall of Famer, to unpack why muscle, not weight loss, is the true driver of metabolic health and longevity. We break down why calorie counting and macro percentages fail, how protein first nutrition reshapes metabolism,

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159 results

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