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PODCAST

Stimulating Brains

Andreas Horn interviews experts in the field of deep brain stimulation, noninvasive neuromodulation, functional brain imaging and neuroanatomy. Join us on our quest to interact with the human brain and thank you for your interest in science! Andreas Horn, M.D., Ph.D., directs the institute for network stimulation and is a professor for computational neurology at University Cologne.

science natural sciences

All Episodes

01:10:46

#13: Mark Humphries – Basal Ganglia Models, Highs and...

Stimulating Brains ·

2021/07/25

It was a tremendous privilege to pick Mark Humphrey's brain who has insight about broad domains of the brain like few others. His new book The Spike: An Epic Journey Through the Brain in 2.1 Seconds takes us on a journey through the brain starting at the retina and ending in the spinal cord. As we follow spikes along, we learn how information is processed in the brain, but also how it's simply lost and forgotten. Mark has done his PhD with Kevin Gurney, who together with Tony Prescott and Peter

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01:11:35

#12: Benjamin Stecher – A personal account of...

Stimulating Brains ·

2021/06/14

Benjamin Stecher is doing impressive work in is role a scientific writer and patient advocate. He co-authored the book “Brain Fables” together with Alberto Espay, which recently won the prose award by the Association of American Publishers in the category Neuroscience. The book is truly unique in its way to combine both the views of patient and health professional on the history and misconceptions of Parkinson's Disease and what should change in our field to make progress. Benjamin was diagnosed

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00:51:20

#11: Katrin Amunts – A modern take on human brain...

Stimulating Brains ·

2021/04/28

Katrin Amunts is the Scientific Research Director of the Human Brain Project and leads two centers at Forschungszentrum Jülich and the University Hospital Düsseldorf. With her internationally recognized work that includes the BigBrain and JuBrain projects and use of novel methodology such as polarized light imaging, she follows the footsteps of famous anatomists of the past, such as Cecile and Oskar Vogt, name givers of her institute. We talk about the relevance of anatomical models and

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01:49:08

#10: Cameron McIntyre – Pushing the frontier of...

Stimulating Brains ·

2021/02/28

Cameron McIntyre and I talk about biophysically plausible deep brain stimulation models that his laboratory has established and continues to refine since about 20 years. Cameron shares insights from a time where DBS modeling was not a thing – how his career choice to step into the realms of medical hospitals as a biomedical engineer had been risky or at least unusual at the time. We learn why the VTA model was originally a step backwards and why there is a large difference between inventions &

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01:50:00

#9: Mac Shine – A thalamus-centric view of basal...

Stimulating Brains ·

2020/12/22

Mac Shine and I talk about Mac's recent intriguing opinion paper that may have radical implications for systems and clinical neuroscience. In it, the thalamus mediates between feed-forward type input from cerebellum, sensori nuclei and cortex one one hand and input from the basal ganglia that introduces an element of randomness. By projecting to the cortex in a specific manner, the thalamus can recruit these inputs to shape the attractor landscape of cortical activations. Mac develops this a theory

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00:55:33

#8: Mojgan Hodaie – Connectivity aided targeting in...

Stimulating Brains ·

2020/12/04

In this guest episode, Luka Milosevic talks with Mojgan Hodaie about the neuromodulation for neuropathic pain, how serendipity may lead to a whole novel research field, how our teachers shape the way we think about the brain and how we may learn from each single patient we get in contact with. Prof. Hodaie is a world-wide expert in stereotactic surgery with a special focus on (imaging guided targeting of) neuropathic pain. The Hodaie lab published the seminal article demonstrating the feasibility of

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00:49:48

#7: Patricia Limousin – Subthalamic Nucleus...

Stimulating Brains ·

2020/11/21

In this episode, we talk with Patricia Limousin about the early days of DBS in the modern era to the current day and about what the future may hold. Building up on episode #4 with Pierre Pollak, we find out how Patricia experienced programming the first bilateral STN-DBS patient, and what has changed over the last 30 years. Professor Limousin has worked at the UCL Institute of Neurology and the National Hospital for Neurology & Neurosurgery since 1997, where she is currently a Professor of Clinical

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01:28:03

#6: Lone Frank – Robert Heath, the forgotten inventor...

Stimulating Brains ·

2020/09/21

In this episode, Lone Frank shares insight about her book “The Pleasure Shock: The Rise of Deep Brain Stimulation and Its Forgotten Inventor” in which she delved into the academic life of a true pioneer of our field. Robert Heath invented deep brain stimulation in the 1950ies and was a remarkable pioneer of our field. Lone's book takes us on a trip delving deep into the discoveries – but also controversies around Heath and his contemporaries, such as José Delgado and Frank Ervin.

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00:39:22

#5: Günther Deuschl – On the importance of...

Stimulating Brains ·

2020/08/22

In this episode, Günther Deuschl shares insight about his life in neurology and the endeavors to transform deep brain stimulation for movement disorders as established treatment options supported by class one evidence. He has been instrumental in multiple major clinical trials, such as the randomized double-blind clinical trial for DBS to the subthalamic nucleus in Parkinson's Disease (Deuschl et al. 2006), a similar study for modulation of the internal pallidum in dystonia (Kupsch et al. 2006) and

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00:55:24

#4 Pierre Pollak – How modern-day Deep Brain...

Stimulating Brains ·

2020/07/05

In this episode, Pierre Pollak shares insight about his life in neurology, music and sports and how he introduced modern-day deep brain stimulation for movement disorders together with Alim Louis Benabid and the team in Grenoble in 1987. After his retirement from academia and neurology, Pierre took up playing piano and spending time with physical activity (cycling, winter sports, etc) – and he mentioned that our conversation was the first about deep brain stimulation he had in over five years. He

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01:38:15

#3: Marwan Hariz – a strong role for imaging and...

Stimulating Brains ·

2020/06/14

In this episode, Marwan Hariz shares insight about why imaging is both the past and the future for deep brain stimulation, how its role of being the “court jester” or “stereotaxy police” emerged and why critical discussions are important for our field.

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01:21:27

#2 Helen Mayberg – Deep Brain Stimulation for Major...

Stimulating Brains ·

2020/05/29

In this episode, Helen Mayberg shares the experience made when the first major depression patient received deep brain stimulation electrodes, some anecdotes about the past and lots of good advice about the future.

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00:52:24

#1: Christian Moll – from Wernicke to Functional...

Stimulating Brains ·

2020/05/24

The German submarine sunk a ship that was carrying Freeman and Watts' handbook to Europe, leading to a delayed start of psychosurgery in Germany. Influence of anatomists like Carl Wernicke or Cecile & Oskar Vogt on the field was strong, with eminent figures like Rolf Hassler paving the was to precision in functional neurosurgery. Christian Moll may be the most experienced electrophysiologist in the DBS field in Germany with a vast knowledge in anatomy. Less known, he is also highly interested in the

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73 results

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