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PODCAST

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade,Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -has redefined what’s possible for the human mind and body. After more than a thousand episodes ofBulletproof Radio, he’s taking it to the next level withThe Human Upgrade™- a masterclass inbiohacking, longevity, and performance optimization.Each episode explorescutting-edge science, advanced technology, and proven biohacksto help youupgrade your energy, focus, metabolism, and resilience.You’ll

health & fitness self-improvement

All Episodes

00:57:09

Death, Legacy & the Philosophy of Longevity — with...

The Human Upgrade: Biohacking for Longevity &... ·

2025/07/01

What if death isn’t inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You’ll learn why some of today’s top thinkers are treating longevity as both a science and a spiritual movement, and how this shift affects your brain, your mitochondria, and your entire approach to life.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave

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00:45:39

Fix What’s Making You Feel Old—From Joints to...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/27

You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden causes of early aging like mitochondrial dysfunction, leaky gut, and chronic inflammation.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with Dr. Gregory Kelly, SVP of Product Development at Qualia Life and a leading

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01:06:15

The Ultimate Guide to a Metabolism That Burns Fat...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/26

93% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap to reboot your metabolism, escape the sugar-burning trap, and reignite your fat-burning engine for good.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down withBen Azadi, functional health expert, best-selling author

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00:49:23

Why Your Workouts Aren’t Giving You a Summer Body —...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/24

You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do instead.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with performance-driven entrepreneur and former Army RangerNick Bare, founder of Bare Performance Nutrition and theGo One Moremovement. With over a decade of

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01:05:01

The Plants That Reverse Aging And Block Daily Toxins...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/19

Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You’ll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxins disrupting your hormones, brain, mitochondria, and overall health. This is a masterclass in biohacking from two experts who’ve spent decades researching how to upgrade the human body.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave

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01:08:34

The Anti-Aging Skincare Trends That Are DAMAGING Your...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/17

Your anti-aging skincare routine might be secretly aging you faster. In this episode, you’ll uncover how trending skincare products including vitamin C serums, harsh exfoliants, and blue light therapies can damage your skin’s mitochondria, accelerate senescence, and trigger systemic inflammation. You’ll learn how to reverse this damage, support cellular repair, and choose smarter formulations that work with your biology for long-term skin and brain health.Watch this episode on YouTube for

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00:43:21

Why Most Supplements Are a WASTE of Money (And What...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/13

Most supplements don’t work, and this episode reveals why. You’ll learn how to stop wasting money on “expensive pee,” how to spot marketing lies on labels, and which ingredients actually move the needle for energy, focus, and longevity.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with Jeff Boyd, founder of MTE and a leader in the new wave of performance supplements. With a background in data-driven wellness and

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00:53:28

Can Injectable MDMA Become the Next Biohack in 2026?...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/12

Psychedelic therapy is on the verge of reshaping mental health, trauma healing, and human consciousness. This episode reveals what’s really happening behind the scenes at the FDA, inside pharmaceutical companies, and within the global movement to legalize MDMA-assisted therapy.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down withRick Doblin, PhD, the legendary founder of MAPS and one of the most influential figures

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01:05:58

Should You Eat Dirt? The “Healthy” Foods Destroying...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/10

You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boostingmitochondria, and rebuilding your biology from the ground up.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with Dr

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00:52:54

How 5G Affects Brainwaves (and the New Science to Fix...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/05

Your brain is under constant assault from devices you use every day. This episode reveals the hidden effects of 5G on brain function, cognitive performance, and nervous system stress, along with the science-backed method that neutralizes the damage.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Aspreysits down with Philipp Samor von Holtzendorff-Fehling, founder of Quantum Upgrade and a former VP at T-Mobile, to explore

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01:22:37

Mark Sisson: The Japanese Walking Hack That...

The Human Upgrade: Biohacking for Longevity &... ·

2025/06/03

Most people think 10,000 steps a day is the gold standard for health, but it’s outdated, inefficient, and often damaging. In this episode, you’ll discover a smarter, faster way to walk for longevity, fat burning, and total body resilience.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down withMark Sisson, bestselling author, primal health pioneer, and founder of Primal Kitchen. With over 40 years at the forefront of

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01:15:05

60 Days Alone in Antarctica: Amputation, Frostbite,...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/29

Akshay Nanavati returns to share how 60 days alone in Antarctica, dragging a 420-pound sled, became a radical experiment in pain, PTSD healing, spiritual transcendence, and the biology of human resilience.

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00:58:34

10-Second Breath Hack to Reset Your Body & Mind |...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/27

This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with Aaron Alexander, a world-renowned human performance coach, manual therapist, and creator ofThe Align Method. Aaron has worked with elite athletes, high-level entrepreneurs, and

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00:59:11

Ayurveda Meets Biohacking: 5000-Year-Old Medicine...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/22

This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down withMona Sharma, a renowned Ayurvedic practitioner, celebrity wellness expert, and functional medicine advocate who grew up in a Canadian ashram. Mona combines ancient Vedic

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01:03:44

The Biohacker’s Guide to CIA Mind Control &...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/20

You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours.Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Science at Harvard University and one of the world’s leading experts on psychological manipulation, surveillance science, government

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01:26:32

Military Tech Goes Public: Think 30% Faster with This...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/16

Discover the brain hack once reserved for Special Forces that boosts reaction time by 30%, sharpens focus, and fuels high-performance thinking—now available to the public.

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00:49:05

The Anti-Aging Chamber That Rewinds Your Biological...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/15

Your cells are starving. Not for food—but for oxygen.In this episode ofThe Human Upgrade, Dave Asprey sits down withDr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science.You’ll learn howhyperbaric oxygen therapy (HBOT)triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if

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01:11:03

The New Science Behind Psychedelics, Exotic Shrooms,...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/13

Your brain has a gear you’ve never touched. Psychedelics can shift you into it.In this episode ofThe Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science.You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave

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01:05:01

Why Oral Testosterone Is the Ultimate Upgrade for...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/09

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it.In this episode ofThe Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixes almost always fail, and how the latest science finally makes testosterone therapy safer, simpler, and more effective than ever before.You will

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01:12:45

The Deadliest Room in Your House — And How to Detox...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/08

Your environment is rewiring your hormones, fertility, and long-term health without your consent.In this episode ofThe Human Upgrade, Dave Asprey sits down withDr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking water, personal care products, and food packaging are hijacking your biology.Dr. Cohen explains how daily chemical exposures contribute to

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