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Journal of Neurophysiology

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Podcasts created by the Journal of Neurophysiology community

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33:56

Sodium sensitivity of KNa channels in mouse CA1 neurons

Journal of Neurophysiology ·

2021/08/20

The Journal of Neurophysiology would like to dedicate the following podcast to Dr. Richard Gray. Dr. Gray passed away at the age of 68 on September 4, 2021. How are potassium channels regulated? How ubiquitous are sodium-dependent potassium channels? In this podcast Editor-in-Chief Professor Nino Ramirez and authors Drs. Richard Gray and Daniel Johnston discuss their manuscript titled “Sodium sensitivity of KNa channels in mouse CA1 neurons.”. In this podcast, the authors discuss KNa channels in

38:17

Compensating for a shifting world: evolving reference...

Journal of Neurophysiology ·

2021/07/12

Auditory and visual information are processed differently by the brain, especially when it comes to space. In vision, the retina senses the locations of images with respect to where the eyes are pointing. In hearing, the cues our brains use to localize sound tell us where the sound is positioned with respect to the head and ears. How then do we perceive space as unified? In particular, how do our brains compensate for eye movements that constantly shift the relationship of the visual and auditory

31:23

The Neurocene-Exploring Developments in the Field of...

Journal of Neurophysiology ·

2021/06/18

In this podcast Editor in Chief Nino Ramirez and Associate Editor Prof. John Krakauer discuss JNP’s new manuscript type the Neurocene. The Neurocene is a narrative that explores accelerating developments in the field of neuroscience, placing them in their historical and present context. Authors should provide a personalized and thoughtful viewpoint of a topic that does not seek to either provide definitive proof or a final conclusion. This long-form scientific essay may focus on cultural currents,

40:38

Respiratory effects of low and high doses of fentanyl...

Journal of Neurophysiology ·

2021/06/11

In this podcast Editor in Chief Nino Ramirez and senior author, Professor Haouzi of Pennsylvania State University discuss the paper titled “Respiratory effects of low and high doses of fentanyl in control and β-arrestin 2 deficient mice”. When life-threatening doses of fentanyl are used in mice, the beta-arrestin2 pathway appears to play a critical role in the recovery from an opioid overdose. This observation calls into question the use of G protein-biased μ-opioid receptor agonists, as a strategy

51:35

The effect of visual uncertainty on implicit motor...

Journal of Neurophysiology ·

2021/06/02

What is sensorimotor adaptation? Why do the authors use this term rather than motor learning? What are some of the key features of sensorimotor adaptation, and in particular, why is the focus here on error-based learning? How do the author's results change the way we think about how visual uncertainty impacts adaptation? Out of the University of California, Professor Richard Ivry and JT Tsay discuss their recently published manuscript titled “The effect of visual uncertainty on implicit motor

40:18

Music-selective neural populations arise without...

Journal of Neurophysiology ·

2021/05/25

What features of a sound does the brain perceive as a pitch? What is the role of rhythm in music? In this podcast Dr. Nancy Kanwisher ( Massachusetts Institute of Technology) and PhD candidate Dana Boebinger (Harvard University) discuss how music-selective neural populations are clearly present in people without musical training, demonstrating that they are a fundamental and widespread property of the human brain. The authors then discuss how music-selective neural populations respond strongly to

40:33

Neurovision: Capturing new ideas and experiments in...

Journal of Neurophysiology ·

2021/05/21

In this podcast Editor in Chief Nino Ramirez discusses JNP’s new article type Neurovision with Prof. John Krakauer of Johns Hopkins University and Prof. Reza Shadmehr of Johns Hopkins University. Neurovision articles aim to move science forward and point out bottlenecks in our understanding of the field. They resemble review articles, but with the inclusion of original data. The presence of new original data is meant to inspire new experiments and ideas. These articles will serve as blueprints, and

50:19

Spatial receptive field structure of double-opponent...

Journal of Neurophysiology ·

2021/05/07

In this podcast Dr. Greg Horwitz of the University of Washington discuses double-opponent cells in macaque area V1, a class of neurons that respond to spatial chromatic contrast in visual scenes. What information they carry is debated because their receptive field organization has not been characterized thoroughly. Using white noise analysis and statistical model comparisons, De and Horwitz show that many double-opponent receptive fields can be captured by either a Gabor model or a

41:41

Synchronous spiking associated with prefrontal high...

Journal of Neurophysiology ·

2021/03/12

In this episode Editor in Chief Prof. Ramirez is joined by Prof Stroh of the University of Mainz and Prof. Totah of the University of Helsinki to discus the manuscript titled "Synchronous spiking associated with prefrontal high gamma oscillations evokes a 5 Hz-rhythmic modulation of spiking in locus coeruleus." Prof. Nelson Totah highlights the main conceptual advances in their paper and talks about what motivated them to focus on top down control exerted by PFC on LC. The prefrontal cortex (PFC) is

34:13

Development and plasticity of complex movement...

Journal of Neurophysiology ·

2021/03/03

The topographic organization of skilled movements seem to be particularly plastic. The author describes how they addressed this issue in their study, and what methods they used. The motor cortex is topographically organized into maps of different body parts. We used to think that the function of motor cortex was to drive individual muscles, but more recently we have learned that it is also organized to make complex movements. In this podcast Prof. Cam Teskey of the University of Calgary discuses in

46:29

The execution of movement - a spinal affair

Journal of Neurophysiology ·

2021/02/26

What does it take to recover walking after a spinal cord injury? If you could replicate this supraspinal control – what aspects would you need? In this podcast Prof Sten Grillner talks about the spinal mechanisms that coordinate locomotion and the interaction between the different sensory mechanisms that help coordinate the locomotor movements and the central locomotor network. Sten Grillner https://doi.org/10.1152/jn.00656.2020 @neuroscience

35:25

Regulation of Vocal Precision by Noradrenergic...

Journal of Neurophysiology ·

2021/02/16

In this podcast, Editor-in-Chief, Nino Ramirez talks with Dr. Marc Schmidt (University of Pennsylvania) about his Research Article which explores recent theories of norepinephrine (NE) function regarding the stimulation of the norepinephrine function that NE can act directly on the motor system to influence the transition between exploratory and exploitative behavioral strategies. Learn how the songbird can act directly on a "cortical" motor area and cause a switch between exploratory and

41:28

Variable but not random: temporal pattern coding in a...

Journal of Neurophysiology ·

2021/02/16

Have you ever wondered how the brain encodes information? How do you crack a code produced within the brain? What are the changes in practicing and performing during development and aging? In this podcast the authors talk about the differences between practice and performance. Be sure to listen to the end for our special guest. S. E. Palmer, B. D. Wright, A. J. Doupe, and M. H. Kao Read the article here: https://doi.org/10.1152/jn.00034.2019 @neuroscience

29:11

Whole brain mapping of somatosensory responses in...

Journal of Neurophysiology ·

2021/01/26

In this podcast Editor in Chief Nino Ramirez interviews first author Justine Clery and senior author Stefan Everling about an insightful new Research Article by Clery et al. Learn more about the advantages of the marmosets as a primate model system for studying primate neuroscience. The authors talk about using somatosensory stimulation combined with functional MRI in awake marmosets to reveal the topographic body representation in areas S1, S2, thalamus and putamen. They showed the existence of a

23:14

Online control of reach accuracy in mice

Journal of Neurophysiology ·

2020/12/10

Have you ever wondered how the brain controls reaching movements, whether mice can perfect a reaching movement and cease making errors, which would resemble a “hot-hand” a phenomenon that has been proposed and discussed in Basketball. What about perfecting reaching movements in the violin? In this podcast Editor-in-Chief Nino Ramirez talks with Dr. Abby Person (University of Colorado), senior author of the study entitled “online control of reach accuracy in mice”. This study uses statistical machine

20:04

Estimation of self-sustained activity produced by...

Journal of Neurophysiology ·

2020/10/14

In this podcast, new Editor-in-Chief Nino Ramirez talks with Dr. Monica Gorassini (University of Alberta) about her recent article which employed a "new method of estimating synaptic drive to multiple, simultaneously recorded motor units" in order to explore the contribution of persistent inward currents to self-sustained firing across motoneuron size. This article was also featured in August's issue of APSselect! "Estimation of self-sustained activity produced by persistent inward currents using

12:18

LRRK2 mutation alters behavioral, synaptic, and...

Journal of Neurophysiology ·

2020/08/12

How does a common Parkinson's Disease-linked mutation affect stress response? In this podcast, Editor-in-Chief Bill Yates talks with Christopher Guevara, Dr. Bridget Matikainen-Ankney, Dr. Deanna Benson, and Dr. George Huntley (Icahn School of Medicine at Mount Sinai) about their Rapid Report article, which explored this question in a mouse model of the LRRK2-G2019S mutation. Listen to learn about evidence of how "G2019S alters the magnitude and direction of behavioral responses to stress that may

09:12

Comparative gain-of-function effects of the...

Journal of Neurophysiology ·

2020/04/20

In this podcast, Editor-in-Chief Bill Yates talks with Dr. Andrea Meredith and Dr. Hans Moldenhauer about their article which compares the effects of different mutations (N999S and D434G) which are associated with the recently-identified neurological disorder called KCNMA1-linked channelopathy. This research was also featured in Episode 4 of the Netflix and New York Times documentary series Diagnosis. Listen to learn about BK channels, gain-of-function mutations, and important clinical implications

12:20

The “embreathment” illusion highlights the role of...

Journal of Neurophysiology ·

2020/01/29

What exactly is corporeal awareness, and how does breathing contribute to this form of self-consciousness? In this podcast, Editor-in-Chief Bill Yates talks with Alessandro Monti, Dr. Giuseppina Porciello, Dr. Gaetano Tieri, and Dr. Salvatore M. Aglioti (Sapienza Università di Roma and IRCCS Fondazione Santa Lucia) about their Rapid Report article, which combined respiration recordings with immersive virtual reality to explore this question. Listen to learn about the embreathment illusion, which

07:32

Estradiol rapidly modulates excitatory synapse...

Journal of Neurophysiology ·

2019/09/24

How does estradiol acutely facilitate sex differences in striatum-dependent behaviors? In this podcast, Editor-in-Chief Bill Yates talks with Dr. Amanda Krentzel and Dr. John Meitzen (both from North Carolina State University) about their study which investigated this question in adult rats. Listen to learn about sex differences, medium spiny neurons, glutamatergic signaling, and more. Also be sure to check out the parallel episode of The Brain That Named Itself podcast, which discusses this study

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