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PODCAST

The Synthesis of Wellness®

Chloe Porter is dedicated to health research and optimization. She is the host of The Synthesis of Wellness ® Podcast; an engineer; and an acclaimed health science speaker, expert, and best-selling author known for her deep dives into gastrointestinal function, functional health, and health optimization.

health & fitness alternative health

All Episodes

00:22:41

122. Babesia (Lyme Co-infection) - Pathology of the...

The Synthesis of Wellness® ·

2024/05/31

In this episode, we explore the intricacies of Babesia and Babesiosis, exploring how this protozoan parasite infects red blood cells and evades the immune system. We discuss the various pathological effects of the infection, including impaired blood flow, tissue ischemia, and multi-organ dysfunction syndrome. Additionally, we cover common symptoms, relevant bloodwork indicators, and an overview of anti-malarial herbs/supplements and other strategies often employed in cases of Babesia. Topics:

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01:01:55

121. Fatty Liver, Metabolic Dysfunction, & Leaky Gut:...

The Synthesis of Wellness® ·

2024/05/29

We are honored to be joined by Brendan Gaughran. Brendan Gaughran, the founder of Liver Medic, holds a degree in Molecular Biology from the University of Connecticut and an MBA from Bentley University. He is an expert in gut health, liver health, the endocrine system, adrenal fatigue, and optimal diets. Brendan frequently conducts health lectures for both physicians and the general public. Through Liver Medic, he manufactures proprietary liver and digestive supplements, leveraging his extensive

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00:21:42

120. Connecting Biotoxin Illness (Lyme Disease) to...

The Synthesis of Wellness® ·

2024/05/24

In today's episode, we explore the connection between biotoxin illness (including Lyme disease) and dysautonomia, as well as nervous system dysfunction, in general. And, we outline strategies for supporting nervous system repair through addressing the root cause and using strategic phospholipid support. Topics: 1. Introduction to the Nervous System - Overview - Central Nervous System (CNS): Brain and Spinal Cord - Peripheral Nervous System (PNS): Connection to CNS, Transmission of

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00:21:28

119. HPA-Axis Dysfunction & The Adrenal Gland Peptide...

The Synthesis of Wellness® ·

2024/05/17

In this episode, we delve into the science behind peptide bioregulators, specifically focusing on Glandokort, a natural extract from the adrenal gland. We explore the unique characteristics and mechanisms of peptide bioregulators, highlighting their tissue-specific effects and role in gene regulation. Additionally, we provide an overview of the adrenal glands' anatomy and functions, and discuss how Glandokort may aid in normalizing adrenal gland protein synthesis in the context of some types of

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00:24:59

118. (Lyme & Mold Part 3) Thymosin Alpha 1 Peptide,...

The Synthesis of Wellness® ·

2024/05/10

In today's episode, we explore the role of Thymosin Alpha 1 Peptide in modulating the immune system, specifically its effects on Th1 and Th2 responses. The episode further delves into the mechanisms by which Borrelia burgdorferi evades immune detection and offers strategies to enhance immune effectiveness against this stealthy pathogen. Additionally, we discuss the broader implications of immune modulation in chronic Lyme disease and mold exposures. Topics: Introduction Recap of the series

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00:26:14

117. (Lyme & Mold Part 2) Biotoxin Illness Binders -...

The Synthesis of Wellness® ·

2024/05/03

In this episode, we undertake a detailed examination of the diverse mechanisms of action underlying various binders employed in detoxification protocols, with a particular focus on their application in biotoxin illnesses such as Lyme disease. We dissect the differential efficacy of bile acid sequestrants like cholestyramine versus natural binders such as activated charcoal and zeolite, elucidating their distinct modes of action in toxin adsorption and excretion pathways. Moreover, we elucidate the

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00:29:27

116. So You've Got Lyme/Mold, Now What? Herxheimer...

The Synthesis of Wellness® ·

2024/04/26

Today I am addressing the "early steps" in combatting Lyme or mold. So, I begin by diving into the phenomenon of Herxheimer reactions, elucidating its occurrence following antimicrobial therapy initiation for Lyme disease. Through this, I explore the intricate interplay between microbial factors, such as the release of endotoxins (LPS), and host immune responses, leading to a cascade of inflammatory reactions. Moreover, I provide practical strategies that may help mitigate Herxheimer

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01:03:42

115. The Biochemistry of Oral Health, Tooth Powder,...

The Synthesis of Wellness® ·

2024/04/22

Today, we are delighted to introduce Justin Bosley, the President and Head Chemist at Evexia Science.Raised amidst health challenges that confounded traditional medical solutions, Justin embarked on a lifelong quest for remedies. Fueled by an innate curiosity and a passion for health and science, he pursued a degree in nutritional science at Brigham Young University. Subsequently, driven by an unyielding commitment to innovation, he augmented his expertise with another degree in chemistry,

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00:29:06

114. Powerful Liver Detoxification Compounds &...

The Synthesis of Wellness® ·

2024/04/19

We are diving into the intricate processes of liver detoxification, from the anatomy of the liver and its blood flow circuitry to the phases of detoxification involving enzymes and conjugation reactions. I highlight the importance of supporting optimal liver function to prevent toxin accumulation and associated symptoms, underscoring the significance of various compounds and peptides, such as Dihydromyricetin (DHM), N-acetylcysteine (NAC), and peptide bioregulators like Svetinorm and Ovagen, in

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01:01:21

113. Unique Superfoods and Adaptogens to Support...

The Synthesis of Wellness® ·

2024/04/15

We are talking all things superfoods today with a focus on enhancing sleep quality and supporting sustained energy levels. Andrew and Allan are the Co-Founders of NoonBrew which is the first superfood tea designed for the afternoon slump. They wanted an alternative to coffee that didn’t keep you up at night and saw that no other beverage company was truly addressing the afternoon energy market. In 2021, they decided to make it themselves. Using Allan’s background in herbal medicine, they blended 19

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00:29:11

112. Lymphatic Drainage Optimization - Peptides...

The Synthesis of Wellness® ·

2024/04/12

In today's episode, we go through the intricacies of lymphatic health in order to understand the mechanisms behind lymphatic congestion, fluid accumulation, and poor immune function. We highlight the pivotal role of white blood cells in orchestrating immune responses and emphasize diverse strategies for maintaining lymphatic flow. We go over herbal supplements, physical therapies, and peptide interventions, also evaluating whether or not they are research-backed. Topics: 1. Introduction to

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00:30:14

111. 6 Peptides to Support The Gut & Aid in Digestion...

The Synthesis of Wellness® ·

2024/04/05

In this episode, we set the stage by going through the intricate anatomy of the gut lining, providing a comprehensive understanding of its layers and cellular components. We, then, explore how six gut-supporting peptides and compounds offer promising therapeutic avenues. From larazotide acetate's tight-junction regulation to KPV's anti-inflammatory properties and BPC-157's reparative effects, we dive into the diverse mechanisms by which these peptides contribute to gut health.Topics:

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00:23:14

110. Intracellular NAD+ Testing, My...

The Synthesis of Wellness® ·

2024/03/29

In this episode, we delve into intracellular NAD+ testing and explore self-experimentation aimed at optimizing NAD+ synthesis. From supporting the salvage pathway, de novo synthesis, and the Preiss-Handler pathway to inhibiting the CD38 enzyme, we will uncover some key nutrients and precursors that will enhance NAD+ stores and production. Topics: 1. Importance of NAD+ - Cellular processes involving NAD+ - NAD+ as a coenzyme for numerous enzymes - Focus on energy metabolism 2. Energy

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00:30:57

109. Methylene Blue - Oxygen Delivery & Utilization,...

The Synthesis of Wellness® ·

2024/03/22

We uncover the various capabilities of methylene blue, particularly its pivotal roles in enhancing mitochondrial function, optimizing energy production, and facilitating oxygen delivery. We also dive into the question of whether its antimicrobial properties impact the gut microbiome in a positive or negative way. Lastly, we explore the downstream effects of improved mitochondrial function, including cognitive and mood enhancement and potential anti-aging benefits.Topics: What is Methylene

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00:28:04

108. Energy Deficiency in Lyme & Mold - How Biotoxins...

The Synthesis of Wellness® ·

2024/03/15

We explore how biotoxins impair cellular function and induce neuroinflammation, leading to systemic inflammation, chronic fatigue, and mitochondrial dysfunction. We also cover how biotoxins disrupt the HPA axis, affecting the body's stress response and adrenal function. Additionally, the conversation presents strategies to mitigate this energy deficiency and combat fatigue in the context of CIRS (lyme & mold).1. Introduction to Biotoxin Illness - Definition and overview of biotoxins -

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01:00:20

107. Emily Johnson, MS, RD, Research Lead at Veri -...

The Synthesis of Wellness® ·

2024/03/11

We are honored to have Emily Johnson on the show today. Emily Johnson, MS, RD, is a registered dietitian with a Master's degree in nutrition interventions, communication, and behavior change from Tufts University. Her background includes clinical nutrition research, health writing, advising, and consulting within the tech sector. At Veri, she is the Research Lead, serving as the health and nutrition expert for the team. In this role, she ensures that Veri's app features, marketing materials,

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00:27:25

106. SS-31 Peptide (Peptides Episode) Deep Dive - How...

The Synthesis of Wellness® ·

2024/03/08

In this episode, we explore the intricate structure and functions of mitochondria, focusing on the electron transport chain complexes and the generation of reactive oxygen species. We delve into the significance of lipid composition in maintaining mitochondrial integrity, the detrimental effects of ROS-induced lipid peroxidation, and how SS-31 can prevent this damage. Additionally, we discuss the potential therapeutic implications of SS-31 peptide not only on the cellular level in mitigating

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00:27:10

105. SS-31 Peptide and Other Supplements in the...

The Synthesis of Wellness® ·

2024/03/01

In this episode, we explore the research behind SS-31 peptide and other supplements as possible groundbreaking interventions for mitochondrial dysfunction, shedding light on their mechanisms as detailed in the scientific literature. We delve into the concept of the mitophagy stack, presenting it as a superior alternative to "Urolithin a" alone, for enhancing the clearance of damaged mitochondria and rejuvenating cellular energy production. Furthermore, we unravel the complex relationship

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00:24:39

104. Regenerating the Gut - A Deep Dive into...

The Synthesis of Wellness® ·

2024/02/23

Today, we are going through pivotal role played by intestinal stem cells in maintaining gut integrity. We explore the impact of aging and factors such as dysbiosis on the depletion of intestinal stem cell pools, leading to impaired epithelial renewal and increased susceptibility to inflammation. Furthermore, we delve into promising research on 3 nutrients / compounds shown to have potential in boosting intestinal stem cell populations (and supporting gut lining regeneration).Topics: 1

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01:00:51

103. Marjorie Tong - EMFs & Electromagnetic...

The Synthesis of Wellness® ·

2024/02/19

Marjorie Tong, Founder and CEO of Juunaday, pioneers the first and only EMF-shielding activewear brand. Offering fashionable apparel, Juunaday empowers women to embrace technology without compromising style for safety. Motivated by her personal journey with electromagnetic sensitivity and fueled by a desire to equip others with essential knowledge, Marjorie combines her background in Fine Arts and Design with a 15-year corporate career and a passion for wellness to create a brand that caters to the

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202 results

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