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PODCAST

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade,Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -has redefined what’s possible for the human mind and body. After more than a thousand episodes ofBulletproof Radio, he’s taking it to the next level withThe Human Upgrade™- a masterclass inbiohacking, longevity, and performance optimization.Each episode explorescutting-edge science, advanced technology, and proven biohacksto help youupgrade your energy, focus, metabolism, and resilience.You’ll

health & fitness self-improvement

All Episodes

00:58:34

10-Second Breath Hack to Reset Your Body & Mind |...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/27

This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with Aaron Alexander, a world-renowned human performance coach, manual therapist, and creator ofThe Align Method. Aaron has worked with elite athletes, high-level entrepreneurs, and

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00:59:11

Ayurveda Meets Biohacking: 5000-Year-Old Medicine...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/22

This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down withMona Sharma, a renowned Ayurvedic practitioner, celebrity wellness expert, and functional medicine advocate who grew up in a Canadian ashram. Mona combines ancient Vedic

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01:03:44

The Biohacker’s Guide to CIA Mind Control &...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/20

You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours.Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Science at Harvard University and one of the world’s leading experts on psychological manipulation, surveillance science, government

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01:26:32

Military Tech Goes Public: Think 30% Faster with This...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/16

Discover the brain hack once reserved for Special Forces that boosts reaction time by 30%, sharpens focus, and fuels high-performance thinking—now available to the public.

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00:49:05

The Anti-Aging Chamber That Rewinds Your Biological...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/15

Your cells are starving. Not for food—but for oxygen.In this episode ofThe Human Upgrade, Dave Asprey sits down withDr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science.You’ll learn howhyperbaric oxygen therapy (HBOT)triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if

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01:11:03

The New Science Behind Psychedelics, Exotic Shrooms,...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/13

Your brain has a gear you’ve never touched. Psychedelics can shift you into it.In this episode ofThe Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science.You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave

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01:05:01

Why Oral Testosterone Is the Ultimate Upgrade for...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/09

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it.In this episode ofThe Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixes almost always fail, and how the latest science finally makes testosterone therapy safer, simpler, and more effective than ever before.You will

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01:12:45

The Deadliest Room in Your House — And How to Detox...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/08

Your environment is rewiring your hormones, fertility, and long-term health without your consent.In this episode ofThe Human Upgrade, Dave Asprey sits down withDr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking water, personal care products, and food packaging are hijacking your biology.Dr. Cohen explains how daily chemical exposures contribute to

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01:04:18

Biohacking Your Heart Health: The Life-Saving...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/06

What if you could reverse the age of your heart...without leaving home?In this episode ofThe Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart’s energy systems.Dr

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00:40:48

How Laser Therapy Boosts Mood, Mental Clarity, and...

The Human Upgrade: Biohacking for Longevity &... ·

2025/05/01

What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition?In this episode ofThe Human Upgrade, Dave Asprey talks with Dr. Brandon Crawford, a leading neurotherapist and founder of 528 Innovations, about the emerging science of laser therapy for the brain and body. You’ll learn how light—when precisely pulsed and targeted—can rewire brainwaves, heal trauma, and even influence states of consciousness.Dr. Crawford explains how specific laser

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01:42:47

Conscious Bacteria? The Secret New Science of...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/29

What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution?In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science of cellular intelligence. Together, they reveal how your mitochondria, microbiome, and genetic memory do far more than support survival—they actively shape consciousness, drive healing, and accelerate human evolution.You’ll discover why chronic disease, fatigue, brain fog, and emotional trauma

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01:06:22

The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/25

You’ve probably heard of HIIT—but have you heard of “REHIT?” This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results.In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness

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01:18:47

The Real Reason You Still Feel Tired—Even When Your...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/24

Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse.In this episode, Dave Asprey talks withDr. Daniel Pompa, a leading voice incellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy.Dr. Pompa shares his personal health collapse and reveals howcellular dysfunction, neurotoxicity, and hormone resistancedrive thechronic fatigue

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01:20:27

The $500 Billion Secret: Why Top Leaders Chase Stress...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/22

Most people run from stress. The world’s highest performers run toward it.Sébastien Page manages over$500 billion in global assets. He’s the CIO of one of the world’s largest investment firms, and he wroteThe Psychology of Leadershipwhile living under relentless pressure. His secret? He doesn’t avoid stress—he uses it as a tool for performance, clarity, and control.But here’s the twist: this isn’t just about boardrooms or billion-dollar trades.Whether you’re running a company, chasing a

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01:30:03

Web3 & the Future of Genetics: AI, Blockchain & Data...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/17

Your DNA, health data, and digital identity areencrypted, monetized, and weaponized against you.But what if there was a way to take it back… and hack the system?In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO ofFulcra.ai, andVishakh, founder ofMonadic DNA—to explore a radical shift in the way we store, protect, and use our most personal data.Together, they break down theWeb3 tech stack powering this revolution. EnterNillion, a distributed,

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00:54:11

Dr. Steven Gundry: Is Fungus Secretly Running the...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/15

If your brain feels foggy, your mood swings like a pendulum, or your cravings seem to control you—this episode will flip what you think you know about your body and your mind. Because what if your thoughts… aren’t really yours?In this mind-altering episode ofThe Human Upgrade, Dr. Steven Gundry reveals a startling new theory: your gut microbiome might be controlling your thoughts. From addiction and depression to obesity and inflammation, the microbes living in your gut—bacteria, fungi,

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00:59:55

Longevity Scientists Discover a Breakthrough Peptide...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/11

If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong?For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what if we could change that?In this episode, Dave Asprey uncovers the cellular

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01:06:13

Identity Hacker: How to Completely Change Your...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/10

What if you could rewrite the code of your personality—on command?Not justcopewith anxiety, overthinking, or social exhaustion… butdeletethe traits holding you back and install better ones?This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods, triggers, and even sense of self aren’t fixed—they’re fluid. And more importantly: they’re up for grabs.Joining him is award-winning journalist from

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00:29:07

Psychedelic States On-Demand (No Substances Needed) |...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/08

Your brain isn’t broken—it’s underpowered.Energy crashes, poor sleep, brain fog, and emotional reactivity don’t just happen. You’re running on low voltage, and your mind pays the price.In this episode, Dave sits down withDr. Patrick Porter, founder of BrainTap, to reveal how toreprogram your brain using light, sound, and guided visualization—no substances, no side effects, no BS.Dr. Porter breaks down how to activate gamma brainwaves, repair trauma loops, access psychedelic-like states, and

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00:51:24

Why Gen Z Can’t Handle the Real World (and How We Can...

The Human Upgrade: Biohacking for Longevity &... ·

2025/04/03

You think you’re helping your kid. You clear the path. You smooth the bumps. You make sure they never feel too sad, too bored, too uncomfortable.It feels like love.But what if it’s making them weak?In this episode, Dave Asprey sits down with bestselling author, TED speaker, and resilience expertJennifer Cohento reveal how today’s parenting norms are quietly producing the most anxious, dependent, and emotionally fragile generation in history—Gen Z.Whether you’re raising kids, managing young

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