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PODCAST

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade,Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -has redefined what’s possible for the human mind and body. After more than a thousand episodes ofBulletproof Radio, he’s taking it to the next level withThe Human Upgrade™- a masterclass inbiohacking, longevity, and performance optimization.Each episode explorescutting-edge science, advanced technology, and proven biohacksto help youupgrade your energy, focus, metabolism, and resilience.You’ll

health & fitness self-improvement

All Episodes

00:14:50

The Boring Secret Behind Celebrities Who Don’t Age :...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/16

This episode reveals how lobsters, telomeres, and a little-known enzyme point to a surprising anti-aging pathway you can activate in just ten minutes a day through simple, evidence-backed practices that help slow cellular aging.

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00:10:00

Biohacking News Weekly Update : 1363

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/14

This week's biohacking roundup covers five major breakthroughs: cocoa extract reducing cardiovascular deaths by 27%, FDA-cleared AI stethoscopes for home health monitoring, the explosive rise of beef organ supplements among women, spirulina's renewed spotlight for longevity and collagen support, and new Senate legislation to protect health data from wearables and wellness apps.

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01:03:49

How to Build Muscle WITHOUT Lifting! Biohacker...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/13

Host Dave Asprey talks with Dr. Sten Stray-Gundersen to reveal how blood flow restriction and intermittent hypoxia training unlock faster strength, hormone, and longevity gains by optimizing oxygen use, vascular health, and mitochondrial performance with minimal effort.

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00:39:28

Why Motivation DOESN’T Work | Mental Biohacks : 1361

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/11

True transformationdoesn’tcome from motivation. It comes from rewiring your mind, reshaping your beliefs, and mastering yourperceptionof reality. This episode reveals how to stop chasing short bursts of inspiration and start creating sustainable change in your thoughts, energy, and biology.You’lllearn how belief, emotion, and neuroplasticity shape human performance, longevity, and resilience—and how to reprogram them for lasting results.Watch this episode on YouTube for the full video

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00:09:22

New Japanese Walking Hack Burns More Fat Than 10,000...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/09

Dave Asprey reveals a powerful Japanese walking method that burns fat faster than 10,000 steps, lowers stress, boosts mitochondrial health, and transforms metabolism in just 15–30 minutes a day.

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00:11:39

Biohacking News Weekly Update : 1359

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/07

Dave Asprey breaks down six new breakthroughs in biohacking and health tech—from melatonin’s hidden heart risks to mitochondrial immune upgrades, AI that decodes cells, and a first-ever blood test for chronic fatigue—giving you the data you need to live longer, think faster, and perform at your peak.

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01:00:08

The Strange Science Behind Tylenol and Heartbreak |...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/06

Painisn’tjust in yourbody,it’sin your brain. In this groundbreaking episode, Host Dave Asprey sits down with Dr. Daniel Amen to reveal how emotional and physical pain share the same neural circuits and how you can rewire them for relief, resilience, and longevity.You’lllearn practical tools to break the “doom loop” of pain, restore neuroplasticity, and retrain your brain for calm, healing, and high performance. This isessentiallistening for anyone ready to stop managing pain and start

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00:37:16

The New SCIENCE of Energy Healing | Biohacking...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/04

Your body does not just run on food or supplements. It runs on energy and information. This episode reveals how to harness that energy for faster recovery, stronger mitochondria, and better emotional resilience. You will learn how energy fields, frequency, and information medicine are reshaping the science of human performance, longevity, and anti-aging.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHostDave Aspreysits down withHarry

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00:21:52

Your Body Has an Anti-Aging Switch (Here’s How to...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/02

Host Dave Asprey reveals why aging isn’t determined by time but by the health of your cells—showing how to measure your true biological age, strengthen your mitochondria, and use fasting, REHIT workouts, and stress-resilience hacks to feel younger, stronger, and more focused at any age

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00:45:24

What Happens When You Live Inside a Quantum Field?...

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/31

Discover how quantum energy, frequency medicine, and consciousness science are rewriting what’s possible for human performance and longevity. This episode reveals how your biofield, mitochondria, and brain can be trained, just like your muscles, to achieve higher focus, deeper resilience, and accelerated healing.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey talks with Philipp Samor von Holtzendorff-Fehling, founder and CEO

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01:10:18

Master Stress in 10 Seconds with THIS Heartbeat...

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/30

Heart rate variability isn’t just a fitness metric, it’s the master signal of human performance, emotional regulation, and longevity. This episode reveals how you can use HRV to hack your nervous system, regulate stress in real time, and build true resilience from the inside out.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey sits down with Rollin McCraty, Ph.D., Director of Research at the HeartMath Institute and a leading

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00:43:13

Biohacking Cannabis: The DNA Science of Plant...

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/28

Discover how decoding your DNA can unlock the full potential of plant medicine. This episode deliversa cannabis masterclass for biohackers, revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You’ll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing.Watch this episode on YouTube for the full video

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00:18:27

This Legal Focus Powder Beats Any Dopamine Detox : 1352

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/26

Dopamine isn’t your real problem — low brain energy is. In this solo episode, Dave Asprey reveals how fatigue in your mitochondria, not dopamine addiction, is what’s draining your focus and motivation — and explains how creatine, the overlooked brain energy molecule, can rapidly recharge your ATP, sharpen cognition, and restore your mental performance in just minutes a day.

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00:05:57

Biohacking News Weekly Update : 1351

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/24

Dave Asprey breaks down five breakthrough stories in biohacking and health-tech — from vitamin D’s anti-aging power to gene-based rejuvenation, gut-driven autophagy, supplement reform, and the rise of AI-powered medical avatars reshaping the future of personalized health.

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00:34:28

How Biohackers Use Nicotine WITHOUT Getting Addicted ...

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/23

This is Part 2 of the Nicotine Masterclass. If you haven’t heard Part 1, start there for a full breakdown of nicotine’s mechanisms, myths, and the science behind its misunderstood role in longevity, nootropics, and human performance.Nicotine is one of the most misunderstood nootropics in the world—and one of the most powerful tools for brain optimization and longevity when used correctly. In this episode, Host Dave Asprey breaks down how to harness nicotine for cognitive enhancement,

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00:57:16

Why Women’s Joints Are Failing 10x Faster : 1349

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/21

Kiran Krishnan reveals how joint degeneration is driven by inflammatory cytokines and poor circulation—and shares breakthrough strategies using nutrition, mitochondrial support, and clinical research to reverse arthritis, rebuild cartilage, and slow biological aging.

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00:12:36

Why You Still Feel Tired And Foggy On A Perfect Diet...

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/19

This episode reveals the hidden biological disruptors—like EMFs, mold, and toxins—that sabotage your energy, focus, and longevity, even when your diet is perfect, and shows you how to eliminate them for truly lasting upgrades.

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00:06:01

10 Minute Weekly Biohacking Update : 1347

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/17

This episode delivers five cutting-edge biohacking breakthroughs—from AI heart scans to brain training and digital twins—plus a five-day protocol to upgrade your biology with real science, not guesswork.

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00:56:52

These Plants Turn On 1,100 Healing Genes In 24 Hours...

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/16

Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You’ll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity.Watch this episode on YouTube for the full video

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00:27:02

Solo Episode - Nicotine Masterclass (pt. 1) : 1345

The Human Upgrade: Biohacking for Longevity &... ·

2025/10/14

Nicotine isn’t just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you’ll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from fear—and exposing the real risks that nobody talks about.Watch this episode on YouTube for the

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