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PODCAST

Discovery Matters

Bethany Grace Armitt-Brewster

A collection of stories and insights on matters of discovery that advance life sciences. Brought to you by the curious people at Cytiva.

science life sciences

All Episodes

27:38

114. Structural biology and crystallography

Discovery Matters ·

2026/01/21

In this episode, we talk with Prof. Tej Pal Singh, a leading figure in structural biology whose work has revealed the shapes and functions of hundreds of important proteins. He shares how these discoveries have helped us better understand immunity, inflammation, and disease—and how they’re guiding new approaches to designing medicines. From breakthrough crystal structures to innovative peptide work, Prof. Singh offers a clear, inspiring look at how structural biology drives modern medical

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24:31

113. Eliminating sleeping sickness

Discovery Matters ·

2026/01/15

Kenya has eliminated human African trypanosomiasis —sleeping sickness — as a public health problem. Dr. Gerardo Priotto from the World Health Organization joins us to explain how Kenya met WHO’s rigorous criteria, the science behind the validation, and the partnerships that made this milestone possible. We unpack the challenges of T.b. rhodesiense, the role of surveillance and community action, and what Kenya’s success means for the global fight against neglected tropical diseases.

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24:50

112. Best of 2025

Discovery Matters ·

2025/12/21

From the mysteries of space to the secrets of the microbiome, from the science of pain to extraordinary stories of resilience and discovery — 2025 was a year to remember. Join Conor, Dodi and the team as they reflect on the highlights on Discovery Matters.

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36:17

111. Brain tumors

Discovery Matters ·

2025/12/17

Brain tumours are among the most complex and challenging conditions in modern medicine. In this episode, we explore what brain tumours are, how they develop, and most importantly, the patient experience.

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19:06

110. Dr Spendlove

Discovery Matters ·

2025/12/08

Discover the story of Dr. Rex Spendlove, the humble scientist behind a breakthrough in cell culture media. From his early days tackling unreliable fetal bovine serum to founding HyClone Laboratories, Dr. Spendlove’s innovations set new standards for scientific research and helped shape modern biotechnology. Join us as we explore how curiosity, collaboration, and a drive to help others can change the world.

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43:14

107. Engineering and preserving the microbiome

Discovery Matters ·

2025/09/18

We’re fascinated by the microbiome — and for good reason. But how do we protect this invisible ecosystem that plays such a vital role in our health?From engineering live, programmable therapeutics that disarm dangerous gut pathogens to creating a global “doomsday vault” to safeguard the diversity of human gut microbes, we dive deep into the cutting-edge science shaping the future of microbiome research.Show notes1. Ronda, C., Perdue, T., Schwanz, L. et al. Precise virulence inactivation using a

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23:09

106. Zoonotic diseases

Discovery Matters ·

2025/06/27

In this episode, we explore zoonotic diseases and their growing impact on global health. Professor Clare Bryant, sheds light on strategies to vaccinate animals to prevent pathogen transmission into humans. We also delve into the historical context of the disease, the role of vaccines, and the importance of coordinated public health.Whether you're a public health professional or simply curious about emerging infectious diseases, this episode offers a comprehensive look at the science, challenges, and

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32:12

105. What is pain?

Discovery Matters ·

2025/05/23

Pain. It comes in many forms: physical and emotional. But do we really understand it?This episode will attempt to answer fundamental questions about what pain is, how it is experienced, and why it is such a critical aspect of human existence. We speak with Prof Jeff Mogil to discuss sex differences in pain. His work has been influential in promoting the inclusion of both sexes in pain research, ensuring that treatments and pain management strategies are more effective for everyone. We are also

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36:57

104. Vaccines as you’ve not met them before

Discovery Matters ·

2025/04/30

Today, we're diving into a topic that's not just reshaping the world of vaccines—it's flipping it on its head. We're exploring the cutting-edge realm of inverse vaccines with Prof Lawrence Steinman and how they're revolutionizing the approach to treating autoimmune diseases. Plus, we'll chat with CancerVax, who are using the immune system in a radically different way, aiming to make it attack cancer cells just like it would fight off a virus like measles.

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30:32

101. Unleashing AI: Adventures in discovery

Discovery Matters ·

2025/03/19

Join us for a fascinating deep dive into how generative AI is revolutionizing healthcare and life sciences! We unveil groundbreaking advancements in drug discovery, clinical trials, and diagnostics—showcasing AI’s growing role in shaping the future of medicine. With expert insights from Shweta Maniar (Google Cloud) and Martin Stumpe (Danaher), we’ll explore how AI accelerates innovation through data-driven breakthroughs while keeping humans at the heart of the process for trust and

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16:43

100. Best of 2024

Discovery Matters ·

2024/12/26

In this special celebratory milestone episode, we mark our 100th episode with a vibrant recap of year. Get ready to dive into fascinating conversations, from the squirrely intelligence of cephalopods and their chameleon-like abilities to cutting-edge antibody drug conjugates (ADCs) revolutionizing cancer treatment, to an enlightening chat with Nobel Laureate Dr. Michael Houghton on the crucial path to combating hepatitis C.

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18:08

94. Discovery Maker: Dr Michael Houghton

Discovery Matters ·

2024/10/10

Dive into the fascinating world of virology as we welcome Nobel Prize-winning virologist Dr. Michael Houghton on this episode of Discovery Matters. We explore Dr. Houghton's groundbreaking work in identifying the hepatitis C virus (HCV) and his enduring quest to combat this global health threat. From the monumental discovery of HCV in 1982 to the revolutionary diagnostic tests that nearly eradicated transfusion-related hepatitis C by the mid-1990s, Dr. Houghton provides an engaging and insightful

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12 results

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