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PODCAST

GasGasGas - Anaesthetic Science for Anaesthesia!

Dr Gas - Anaesthesia Education

An Anaesthesia Podcast focusing on the science knowledge anaesthetists should know. We track the UK Primary FRCA Curriculum.> GasGasGas will fit into a corner of your day, delivering a treatise on a drug, concept or practice critical to the knowledge required to pass the FRCA Primary Exam! > There are naturally tangents, as hearing a word vomit of data with no joy is not the aim of Dr gas! > This is relevant to anyone in the world interested in these pharmacological, physiological,

health & fitness medicine

All Episodes

30:53

Cisatracurium + other drugs that impair neuromuscular...

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2026/02/20

Cisatracurium is one of the ten isomers found in an ampoule of Atracurium! It has been selected out as a useful, potent, predictably degrading drug with a very stable side effect profile!Althought, it might be that, whilst Cisatracurium probably sounded like a great idea at the time... it was perhaps batting for a marketing USP that wasn't quite there.. If we were being particularly clever we could call it the R-cis-R'-cis isomer of Atracurium besilate, it is 3 times as potent as the Atracurium mix

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25:10

Mivacurium + mischief with plasma cholinesterase

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2026/02/06

Mivacurium, a drug that is perhaps not found in your cupboard anymore! It does have a number of interesting properties, which does make it a worthy exam question and a useful example of geometric isomerism!Listen to find out more Show notes at:https://gasgasgas.uk/mivacurium ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate] Contributions to

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42:34

A not so brief jaunt with Oxygen, toxicity, exploding...

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2026/01/23

The ubiquity of oxygen in the curriculum is directly correlated with its importance! One of many episodes that focus on the facets o knowledge needed to understand how oxygen does its thing. Today, when too much oxygen is a bad thing, how it is obtained, transported in hospitals and the negative implications of its use + some history that I know you all deeply desire! Show notes at: https://gasgasgas.uk/oxygen-for-the-frca-primary/ ================================================ GasGasGas -

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37:20

GasGasGas - Nitrous Oxide

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2026/01/09

Nitrous Oxide, once a corner stone of 'passing the gas' has been progressively displaced by better agents, think sevoflurane with less PONV, remifentanil for rapid titratable pain relief and even desflurane for its speedier offset.This episode handles everything you need to know and more for the exams! Show notes at: https://gasgasgas.uk/ether_enflurane_explosions/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach me

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58:08

GasGasGas - Ether, Enflurane and Explosions!

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/12/29

The 2025 Bumper Christmas Special, delving into the delights of Ether, Enflurane and Explosions (+ fires)We find out a little bit about the first Ether anaesthetic, and then get to grips with what an explosion is, and why understandably it was problematic for anaesthetists. Show notes at: https://gasgasgas.uk/ether_enflurane_explosions/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach me Anaesthetics Check out the Teach

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35:49

GasGasGas - Desflurane + An Intro To Vapourisers

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/12/12

I've checked the house, there are no polar bears so we should be fine to talk about this drug.Desflurane is pricey, polar bear poison that you may get examined on! Check it out! Show notes at: https://gasgasgas.uk/desflurane-and-vapourisers/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate] Contributions to keep the lamps lit

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20:02

GasGasGas - Halothane

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/11/28

With the advent of halothane, smoking, static and other sizzling was back in style! Gone were the explosive diethyl ether, acetylene, trichloroethylene and cyclopropane anaesthetics of the 1950's and with it a new era of fewer explosions, and possibly a greater prevalence of post operative liver distress.GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/halothane/↗ Teach me Anaesthetics Sponsorship ———————— Donations to keep the lights on willingly accepted! Paypal

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30:10

GasGasGas - Sevoflurane

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/11/14

Having a solid understanding of Sevoflurane is, as you might expect, quite important for the FRCA primary and your career. as it is likely the most commonly used volatile anaesthetic agent, at least in the UK.It might find itself adjacent to a Desflurane or Isoflurane vaporiser, and compared to these a few properties stand out, its the smoothest option for Gas Induction, it has the least offensive global warming potential, and has reasonable onset/offset (Although, Desflurane is a winner here, n.b

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24:20

GasGasGas - Isoflurane

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/10/31

This Primary FRCA podcast episode introduces you to Isoflurane, a ubiquitous and fairly cheap volatile anaesthetic agent that always seems to be left alone while its sevoflurane friend lives the high life, This episode probably won't sway your use, but if you walk into an anaesthetic halfway thru and have no idea what your ET for MAC-1 is, then this is for you!GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/isoflurane/↗ A podcast for the Primary FRCA

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29:36

GasGasGas - Introducing Volatiles!

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/10/17

This Primary FRCA podcast episode introduces you to Volatile anaesthetic agents and the pharmaceutical particulars that make their behaviour through a human very interesting!We cover Blood gas and oil gas partition coefficients, Saturated vapour pressure, critical temperature and boiling points - and touch on pharmacodynamics and the Viva Question 'What is the ideal anaesthetic agent' approach. GasGasGas - putting knowledge in your brain! Show notes at:

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26:11

GasGasGas - Opioids Quiz, the second attempt

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/10/13

Yet again, the sound engineer has been sacked........Apologies that this is a second attempt at an Opioids Quiz, the music cuts went rather wrong - so we've slung the music in the bin! This is a straight up quiz, with gaps so you can think up an answer and then, as you might expect... an Answer! The goal isn't to give you verbatim words to regurgitate but to build up these facts in your mind so then next time you cover it you've foundations to build upon! GasGasGas - putting knowledge in your

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19:30

GasGasGas - Clonidine

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/10/03

Clonidine is a drug found in many a cupboard, acting as a useful adjunct for pain, sedation and having utility in smoothing out post op emergence, it has off license use as a adjunct in regional and neuraxial blockade (at least in the literature!)GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/clonidine/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on: BlueSky: Gas Gas Gas

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24:52

GasGasGas - Dexmedetomidine

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/09/26

Dexemedetomidine is a drug that it seems we are really only just getting our hands on in the UK, it is an Alpha 2 AGOnist causing sedation, anxiolysis and some analgesia. This episode of GasGasGas explores its use, mechanisms side effect profile and kinetics GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/dexmedetomidine/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on: BlueSky: Gas Gas Gas

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19:10

GasGasGas - Midazolam

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/09/19

Midazolam represents the cornerstone benzodiazepine in perioperative medicine, offering rapid onset sedation, anxiolysis, and amnesia with predictable pharmacokinetics. Understanding its mechanism, dosing strategies, and clinical applications is fundamental for safe anaesthetic practice and optimal patient care.GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/midazolam/ A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly

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19:50

GasGasGas - Etomidate

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/09/12

Having an Iota of a Scooby-Doo about Etomidate is perhaps what is required for the FRCA primary exams. We've gone into naturally more detail when we're talking Etomidate for gasgasgas, because we love a bit of detail. This episode covers the pharmacodynamics and pharmacokinetics of Entomidate, but also explores briefly steroidogenesis and what the implications of this is clinically GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/etomidate-for-the-frca/ A podcast for

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29:24

GasGasGas - Classifying Isomers!

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/09/05

Understanding molecular stereochemistry is fundamental to modern anaesthetic practice. The three-dimensional arrangement of atoms within drug molecules directly impacts their pharmacological properties, with some arrangements being therapeutically beneficial while others may be inactive or even harmful. This episode explores the critical concept of isomerism in anaesthetic drugs, with particular focus on how molecular handedness affects drug choice.GasGasGas - putting knowledge in your brain! Show

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26:53

GasGasGas - Peri-Neural LA Adjuncts

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/08/29

Welcome to the final local anaesthetic episode - Peri-neural adjuncts- because we should not forget the medley of mixing options that you could stir into your NRfit cauldron.... although most folks don't.GasGasGas - putting knowledge in your brain! Show notes at: Link incoming A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) /

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17:25

GasGasGas -Local Anaesthetics Quiz

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/08/22

Welcome to an experimental episode of GasGasGas - where you get the joys of a quiz after listening to all these episodes on local anaesthetics agents. Let me know if you think it's pants.GasGasGas - putting knowledge in your brain! Show notes at: coming Friday day A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook

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14:00

GasGasGas - Compare & Contrast Local Anaesthetics -...

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/08/22

Welcome to another essential episode of Gas Gas Gas, where we summarise all the local anaesthetic content we have covered - In order to get you fired up for the most exciting quiz on local anaesthetics you've ever had the pleasure of listening to. GasGasGas - putting knowledge in your brain! Show notes at: coming Friday day A podcast for the Primary FRCA Exams ———————— Donations to keep the lights on willingly accepted! Dr Gas Lurks on: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X /

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34:27

GasGasGas - Local Anaesthetic Systemic Toxicity

GasGasGas - Anaesthetic Science for Anaesthesia! ·

2025/08/14

Welcome to Local Anaesthetic Systemic Toxicity!!(LAST) represents one of the most clinically significant complications in regional anaesthesia practice. This episode explores the pathophysiology, recognition, and management of LAST with particular emphasis on emergency management protocols and risk mitigation strategies. Understanding LAST is crucial for safe regional anaesthesia practice, as it can occur with any local anaesthetic administration and requires immediate, systematic

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