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PODCAST

Optimal Protein Podcast with Vanessa Spina

Vanessa Spina is a Sports Nutrition Specialist, Best Selling author, creator of the innovative TONE device, as well as a sought after international speaker. On the Optimal Protein podcast, Vanessa shares how to get effortlessly lean and improve metabolic health and fitness with an optimal protein intake! Featuring interviews with world renowned and leading edge protein scientists & experts, authors, and people with inspiring transformational stories discussing the best tools for becoming

health & fitness nutrition

All Episodes

01:08:16

The Muscle Strategy Every Woman Needs — Dr. Gabrielle...

Optimal Protein Podcast with Vanessa Spina ·

2026/01/05

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode of the Optimal Protein Podcast, I'm joined by Dr. Gabrielle Lyon to break down the muscle-centered strategy every woman needs for fat loss, metabolic health, and long-term strength. We unpack why muscle — not hormones alone — is the key driver of body composition, why midlife fat gain is not inevitable, and how protein

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43:14

2026 Goal Setting Masterclass: How to Set Health &...

Optimal Protein Podcast with Vanessa Spina ·

2026/01/02

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Most people don't fail at their goals because they lack discipline — they fail because they were never taught how to set goals that actually work. In this New Year solo episode, Vanessa shares a powerful, step-by-step goal-setting masterclass inspired by Tony Robbins and Brian Tracy, applied specifically to fat loss, body recomposition,

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01:29:58

2025's Biggest Body Recomposition, Fat Loss & Protein...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/29

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In today's episode, I'm continuing our Best of 2025 series with a powerful follow-up to Friday's episode. Instead of an interview, this is a curated masterclass pulling together the most important breakthroughs of 2025 in body recomposition, fat loss, and protein metabolism — especially for women navigating perimenopause and midlife

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58:48

A Personal Announcement + The 5 BIGGEST TAKEAWAYS &...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/27

Study takeaways start at 18:00 mark Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this special end-of-year solo episode, Vanessa shares a brief personal announcement, followed by the five biggest scientific takeaways from 2025 that reshaped how she thinks about fat loss, longevity, and metabolic health. Tthis episode highlights the studies and expert conversations featured on the

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01:28:29

Gut Health, Hormones & Midlife Weight Gain — What...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/23

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode of the Optimal Protein Podcast, Vanessa is joined by Cynthia Thurlow, nurse practitioner, bestselling author, and women's health expert, for a deep dive into why fat loss and muscle maintenance become more challenging during perimenopause and menopause. Cynthia explains how hormonal shifts drive anabolic resistance, reduce

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01:09:03

The New Peptide Science: Reversing Skin Aging,...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/20

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa What if the real driver of skin aging isn't wrinkles or sun damage — but "zombie" senescent cells hiding in your skin? In this episode of the Optimal Protein Podcast, Vanessa sits down with Dr. Alessandra Zonari, PhD — a stem cell biologist and longevity scientist — for a fascinating deep dive into the new peptide science behind skin aging,

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01:00:52

Why You Can't Diet Forever: Study Results From 10,000...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/15

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Why do so many people lose weight — only to regain it later? In this episode of The Optimal Protein Podcast, Vanessa Spina sits down with Dr. Holly Wyatt, physician, endocrinologist, and longtime researcher with the National Weight Control Registry (NWCR) — the world's largest and longest-running study of people who have lost weight and kept

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52:27

BREAKING NEWS EXPLAINED: Your Metabolism Isn't...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/12

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa For nearly a decade, many of us have believed that calorie burn eventually plateaus—that once you move enough, your body quietly compensates and stops burning more energy. That belief has shaped how we diet, how we train, and even whether we bother moving more at all. But a brand-new 2025 human study challenges that idea in a way that could

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01:11:33

BREAKING: Your Body Burns More Calories Than We...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/08

Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In today's episode, Vanessa sits down with Dr. Howard, the lead author of a brand-new PNAS study that is challenging one of the most widely accepted ideas in human metabolism. For years, many scientists believed that our bodies operate within a fixed daily calorie "budget," and that after a certain point, increasing activity doesn't increase

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46:08

Shocking New Research on Creatine & Collagen: What...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/05

In today's episode, Vanessa reveals the shocking new human research on two of the most powerful and science-backed supplements for women's fat loss, muscle tone, metabolic health, skin rejuvenation, and longevity: creatine and collagen. You'll discover why creatine is no longer just a gym supplement, and how groundbreaking new data shows collagen may actually influence biological age. This episode is packed with cutting-edge insights every woman needs to hear. Timeline Mitopure Gummies — The #1

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01:18:06

Is Intermittent Fasting Sabotaging Your Muscle? The...

Optimal Protein Podcast with Vanessa Spina ·

2025/12/01

NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In this science-packed episode, Dr. Cas Fuchs breaks down the surprising ways intermittent fasting, under-fueling, cold plunges, and low glycogen can quietly sabotage your muscle, strength, and body recomposition goals. We uncover the truth about IF for active women, what really matters for protein timing and distribution, how

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47:37

Why I Quit Intermittent Fasting & Lost 13+ Lbs of Fat...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/28

🔥 BLACK FRIDAY IS HERE — 30% OFF SITEWIDE! My biggest sale of the year is live! Get 30% OFF all Tone Devices, red light panels, masks, and more at KetogenicGirl.com with code BF2025. 👉 Shop the sale HERE In this episode, Vanessa reveals why she quit intermittent fasting after nearly a decade — and how she went on to lose 13+ pounds of fat by switching to a completely different approach that's supported by new human research. You'll learn why many popular fasting "benefits" were based on rodent

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01:20:58

Fat Loss for Women: What Actually Works — with Dr....

Optimal Protein Podcast with Vanessa Spina ·

2025/11/24

🔥 BLACK FRIDAY IS HERE — 30% OFF SITEWIDE! My biggest sale of the year is live! Get 30% OFF all Tone Devices, red light panels, masks, and more at KetogenicGirl.com with code BF2025. 👉 Shop the sale: https://ketogenicgirl.com/discount/BF2025 OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code

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34:40

Stop Midlife Belly Fat: The New Science on Protein &...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/21

Here it is 🖤 BIOptimizers Black Friday: Get 25% off + exclusive free gifts now through Dec 3 on favorites like Magnesium Breakthrough and MassZymes. 👉 bioptimizers.com/vanessa Code: VANESSA Don't miss the year's biggest savings! In today's Friday solo episode, I'm recapping one of my favorite conversations on women's health, metabolism, and body composition with Dr. Hannah Cabré — postdoctoral researcher at Pennington Biomedical Research Center and Fellow of the Year 2025. We break down why

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01:16:03

Muscle Loss, Belly Fat & Perimenopause: What's REALLY...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/20

NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In today's episode, we take a powerful deep dive into women's metabolism during perimenopause and midlife with Dr. Hannah Cabré, postdoctoral fellow at Pennington Biomedical Research Center and 2025 Fellow of the Year. We break down why body composition changes so dramatically for women in their late 30s, 40s, and 50s — and what

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01:01:22

Part 2: PSMF Ask Me Anything: Rapid Fat Loss, Protein...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/14

Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa This is Part Two of our PSMF Ask Me Anything series! In this episode, Vanessa answers your most practical and frequently asked questions about how to implement a Protein-Sparing Modified Fast in real life — including how to adapt it around your family, your menstrual cycle, different body sizes, refeeds, supplements, ketone readings,

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57:32

PSMF Ask Me Anything: Rapid Fat Loss, Protein to...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/10

In this Ask Me Anything episode, Vanessa breaks down your most common questions about the Protein-Sparing Modified Fast (PSMF) — one of the most powerful evidence-based tools for rapid fat loss and muscle preservation. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA You'll learn exactly how to calculate your macros, when to schedule refeeds, how to adapt PSMF for your

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44:44

Burn Fat, Keep Muscle: Inside the Science of the...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/07

Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In this solo episode, Vanessa Spina breaks down the science and strategy behind one of the most effective tools for rapid fat loss and muscle preservation — the Protein-Sparing Modified Fast (PSMF). Following her in-depth interview with Dr. David Jockers, Vanessa explains exactly how this approach works, why it's so powerful for

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01:07:01

How to Lose 10–20 Pounds of Fat in 30 Days: The...

Optimal Protein Podcast with Vanessa Spina ·

2025/11/03

Learn how to lose 10–20 pounds of fat in one month—without losing muscle or wrecking your hormones. Dr. David Jockers joins Vanessa to break down the Protein-Sparing Modified Fast (PSMF): the macros, meals, training, and refeed strategy that make this rapid fat-loss reset both safe and effective. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA What if you could lose up to 20

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39:55

How to Eat for Fat Loss Without Losing Muscle: What...

Optimal Protein Podcast with Vanessa Spina ·

2025/10/31

Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In this solocast episode, Vanessa breaks down the latest research from Dr. David Church — a rising leader in protein metabolism — to reveal exactly how to eat for fat loss without losing muscle. Discover how stable isotope tracer studies reveal the truth about protein timing, fasting, and essential amino acids — and how to apply

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