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PODCAST

The Heart of Healthcare | A Digital Health Podcast

Massively Better Healthcare

🏆 #1 podcast in the Top 100 Health Tech All-time chartsJoin us every Monday for conversations with the biggest names in digital health. Hosted by digital health veterans Halle Tecco, Michael Esquivel, and Steve Kraus.Learn more and submit your ideas for the show at the Heart of Healthcare website.

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All Episodes

00:35:47

🔮 2026 Digital Health Predictions | Annie Lamont

The Heart of Healthcare | A Digital Health Podcast ·

2026/01/12

Is 2026 the year that changes everything in healthcare?Steve and Halle sit down with legendary healthcare VC Annie Lamont for their annual predictions episode to dive into 2026 predictions and trends that founders and operators should pay attention to. We cover: 📉 Why 2025 was "the most brutal year ever" for health plans 🏥 Why providers outpaced payers in AI adoption and where the next wave of enterprise software will land 💸 Where she’s spending her time in 2026 (and what space she’s

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00:35:40

The Antidote to the “Industrial Wellness Complex” |...

The Heart of Healthcare | A Digital Health Podcast ·

2026/01/05

For our first episode of 2026, Dr. Ezekiel “Zeke” Emanuel, oncologist, bioethicist, architect of the Affordable Care Act, and author of Eat Your Ice Cream joins us to share why he believes the longevity movement is overblown and how real health comes down to simplicity. In his new book, Zeke argues that instead of chasing expensive fads and wellness trends, we should focus on six straightforward habits that make life healthier and more enjoyable. In this conversation with co-host Steve Kraus, he

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00:46:11

Former Presidential Candidate Gets Real About...

The Heart of Healthcare | A Digital Health Podcast ·

2025/12/29

We’re closing out the year with a candid conversation about where America is headed.For our final episode of 2025, Halle and Steve sit down with entrepreneur and former presidential candidate Andrew Yang to talk plainly about the forces reshaping American life, from rising healthcare costs and gaps in coverage to AI-driven job disruption and the strain on the social safety net. We cover: 🏛️ Andew’s idea of “Medicare for all who want it” 🤖 How AI is already wiping out entry-level jobs, and

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00:36:40

The Rise of Clinician Innovators | Dr. Reena Pande

The Heart of Healthcare | A Digital Health Podcast ·

2025/12/22

Many clinicians quietly wonder if there's a “next chapter” beyond the hospital walls, and an increasing number are stepping into health tech roles that didn’t exist a decade ago. Dr. Reena Pande has lived that shift firsthand: from cardiologist at a top academic center, to early employee and CMO at AbleTo, to now leading clinician executive search at Oxeon. She joins us to unpack what it really takes for clinicians to succeed in startups, why these roles matter more than ever, and how AI is

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00:30:10

Soul-Driven Healthcare Investing | General Catalyst...

The Heart of Healthcare | A Digital Health Podcast ·

2025/12/15

Hemant Taneja believes you can sneeze and reach a billion dollars in healthcare revenue, but that most of that revenue tells you nothing about whether the system is actually getting better.This week, Halle sits down with the CEO of General Catalyst and author of The Transformation Principles to discuss what happens when you stop treating revenue as the primary KPI and start asking harder questions about impact, incentives, and system change. They get into his “health assurance” thesis, what it

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00:45:11

The Haves & Have-Nots Of 2025 | Threshold Ventures...

The Heart of Healthcare | A Digital Health Podcast ·

2025/12/08

This week for our 2025 recap, we’re joined by VC Emily Melton, co-founder of Threshold Ventures. Melton highlights her reflection of 2025, which splits the market into "haves and have-nots" with nothing in between, noting the concentration of venture dollars on "high flyers" and the indifference shown to established companies with respectable revenue.

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00:34:19

📣 Digital Health Download: December 2025

The Heart of Healthcare | A Digital Health Podcast ·

2025/12/01

The first trillion-dollar healthcare company, a $298M longevity round, and a telehealth CEO headed for federal sentencing. Last month had range.Today on the show, Halle and Michael sort through the biggest December stories shaping the year ahead, from runaway longevity funding to a telehealth scandal headed for federal sentencing. We cover: 🧬 Two hot funding rounds in longevity, including Function Health’s $298M B-round and Blueprint’s all-angel, no-VC $60M raise 💊 How Eli Lilly became the

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00:34:55

Fixing Rural Healthcare Before It Collapses |...

The Heart of Healthcare | A Digital Health Podcast ·

2025/11/24

As millions of Americans hit the road to visit family for Thanksgiving, many will pass through, or return to, rural communities. Nearly 60 million Americans live in these areas, yet many struggle to access even basic healthcare as rural hospitals close at record rates.Dr. Jennifer Schneider, co-founder and CEO of Homeward Health, is tackling this crisis head-on by reimagining how care is delivered to Medicare Advantage members in rural America. Drawing on her experiences as a physician, a patient

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00:36:02

How a Small Team Built the Fastest-Growing Clinician...

The Heart of Healthcare | A Digital Health Podcast ·

2025/11/17

On the heels of raising $210 million at a $3.5 billion valuation, OpenEvidence is the fastest-growing physician app in history, now reaching over 40% of U.S. physicians and powers 17 million monthly clinical queries.

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00:47:28

Truth, Power, and the Cost of Speaking Up | Theranos...

The Heart of Healthcare | A Digital Health Podcast ·

2025/11/10

A billion-dollar startup. A promise to change healthcare forever. And behind the scenes… a massive lie.

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00:39:44

📣 Digital Health Download: November 2025

The Heart of Healthcare | A Digital Health Podcast ·

2025/11/03

Does it feel like we packed in a decade of progress this year in digital health? We think so. Today, Halle and Steve break down the biggest digital health stories of the moment, from funding trends to AI rivalries and new rules shaping the future of care.

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00:31:41

UpToDate’s AI Glow Up | Wolters Kluwer Health VP BD &...

The Heart of Healthcare | A Digital Health Podcast ·

2025/10/27

Over 3 million clinicians around the world depend on UpToDate to guide patient care, and now the gold standard in clinical decision support is integrating generative AI. But in a world where AI models often hallucinate, how do you build something that doctors can actually trust?In this episode, Halle talks with Dr. Holly Urban, VP of Business Development and Strategy at Wolters Kluwer Health, about UpToDate Expert AI, a new tool trained exclusively on UpToDate’s physician-authored content — not

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00:42:57

Inside the Rise of AI Agents | Sierra Co-founder Clay...

The Heart of Healthcare | A Digital Health Podcast ·

2025/10/20

Most people spend over 30 hours a year dealing with customer service—on hold, repeating account numbers, and navigating endless phone trees. But what if AI could fix that without losing the human touch?Clay Bavor, co-founder of Sierra (now valued at $10B) and former VP at Google, joins us to explore how AI agents are reshaping how companies interact with customers and what that means for the most complex service industry in the world: healthcare. We cover: 🧠 The difference between horizontal

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00:32:32

Build, Scale, Repeat | Serial Founder Tom X. Lee

The Heart of Healthcare | A Digital Health Podcast ·

2025/10/13

This milestone 200th(!!!) episode of The Heart of Healthcare Podcast features none other than Dr. Tom X. Lee, the serial physician-founder behind Epocrates (acquired for $293M), One Medical (acquired by Amazon for $3.9B), and now Galileo, a tech-enabled medical group aiming to rewire care delivery from the ground up.We cover: 🧠 Why most doctors aren’t wired for management (and what traits he thinks translate to startup success) 📉 How medical education is falling behind the pace of change in

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00:40:06

📣 Digital Health Download: October 2025

The Heart of Healthcare | A Digital Health Podcast ·

2025/10/06

Happy Q4 Heart of Healthcare Listeners! We’re back with your monthly Digital Health Download, where we discuss the biggest industry headlines of the month. We cover: 💊 Pharm tariffs, D2C drug ads, and TrumpRx? 📉 The ACA tax credit standoff and how it could double premiums for millions 🛒 UnitedHealthcare’s new storefront and what it signals about point solution fatigue 📈 The GLP-1 gold rush: Remedy’s $450M revenue, Virta’s $160M, and FDA’s warning shot ⚖️ The Doximity vs. Open Evidence

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00:30:40

Can We Make Cancer Nonlethal? | Reed Jobs & Matt...

The Heart of Healthcare | A Digital Health Podcast ·

2025/09/29

Cancer drugs cost more than ever, yet survival benefits are often modest—and in some cases, patients can’t even access the care that already exists. After losing his father, Steve Jobs, to pancreatic cancer, Reed Jobs committed himself to making this the last generation that loses parents to the disease. Reed now leads Yosemite, a venture fund spun out of Emerson Collective in 2023, alongside Investor Matt Bettonville. Yosemite pairs life sciences and digital health investments with a grantmaking

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00:43:52

Lessons From 5,000 Hours of Startup Pitches | EIC of...

The Heart of Healthcare | A Digital Health Podcast ·

2025/09/25

Some founders win support because of their product, others because of their story. In healthcare, where trust is everything, the ability to tell a compelling and authentic narrative can make or break a company.

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00:43:25

Can Wearables Move from Wellness to Medicine? | ŌURA...

The Heart of Healthcare | A Digital Health Podcast ·

2025/09/22

Thanks to improved accuracy and new form factors, wearables have evolved from novelty step counters to tools that can predict illness, nudge healthier behaviors, and even influence alcohol consumption. But can they really bridge the gap between consumer wellness and enterprise healthcare?In this episode, ŌURA CEO Tom Hale discusses the lessons his team has learned from developing one of the most widely used health-tracking devices. We explore what draws people to wearables, what sustains their

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00:43:12

Dissecting the BVP State of AI Report 2025 and What...

The Heart of Healthcare | A Digital Health Podcast ·

2025/09/15

AI companies are hitting growth milestones in record time—some reaching $100 million in revenue in just two years. But while this pace feels familiar in tech, healthcare has always been slower to adopt new tools. That may finally be changing.

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00:29:57

📣 Digital Health Download | September 2025

The Heart of Healthcare | A Digital Health Podcast ·

2025/09/08

Healthcare’s “back-to-school” season delivered no shortage of big headlines! From Epic’s big leap into AI to a looming insurance “blood bath,” Steve and Michael break down the stories that shaped digital health this month.We cover: 🖥 Epic’s 200 new AI “colleagues” and what it means for the battle between systems of record vs. systems of action 💼 Why healthcare CEOs are cashing record paychecks despite shaky stock performance 📉 The warning signs of soaring insurance premiums and their

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212 results

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