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Sensible Medicine

Sensible Medicine Authors and Editors

Common sense and original thinking in bio-medicine A platform for diverse views and debate www.sensible-med.com

science medicine

All Episodes

38:37

This Fortnight in Medicine XXXV

Sensible Medicine ·

2026/10/07

Colorectal Cancer and Mortality Risk Among Older Adults With vs Without Adenoma on Prior Colonoscopy* The Hubris of Screening for Disease — AgainPrognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment* Why Blood Tests Are a Poor Screening Tool for Alzheimer’s This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

31:48

This Fortnight in Medicine XXXIV

Sensible Medicine ·

2026/09/23

Cancer-Related Mortality Among US Pilots and Flight AttendantsResponse-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

19:32

Lecture 8 - endpoints

Sensible Medicine ·

2026/09/22

Our free series is almost over This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

29:59

Lecture 7

Sensible Medicine ·

2026/09/15

New lectures coming soon (after part 9) This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

9:33

Friday Reflection 63: Foxes, Hedgehogs, Generalists,...

Sensible Medicine ·

2026/09/11

This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

9:44

Fortnight in medicine

Sensible Medicine ·

2026/09/09

A royal mistake This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

35:10

Lecture 6 KM Curves

Sensible Medicine ·

2026/09/08

we are making all the old episodes available for free, and then on to the new ones-v This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

43:15

Lecture 5

Sensible Medicine ·

2026/09/01

New episodes coming soon. First 9 parts free now. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

50:36

This Fortnight in Medicine XXXIII

Sensible Medicine ·

2026/08/26

Coronary-Artery Revascularization before Elective Major Vascular SurgeryDiscontinuation of statins for primary prevention of atherosclerotic cardiovascular disease in adults aged 75 years or older (SAGA/SITE): a multicentre, open-label, pragmatic, non-inferiority randomised trial This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

36:40

Lecture 4 - How not to be fooled

Sensible Medicine ·

2026/08/25

I notice that someone was angry that we are re-posting old episodes BEFORE we post the new ones. Just a reminder, we said we would do this! We will make the old ones available for free, and then post the new ones. Bear with us.In the meantime, enjoy. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

35:06

Lecture 3: How Not to Be Fooled - VP's Intro

Sensible Medicine ·

2026/08/18

And here is lecture 3 of How Not to Be Fooled series19 parts coming! 9 for free, and 10 for subscribers. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

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46:25

This Fortnight in Medicine XXXII

Sensible Medicine ·

2026/08/12

Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical TrialImpact of cognitive training on claims-based diagnosed dementia over 20 years: evidence from the ACTIVE study This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

41:52

This Fortnight in Medicine XXXI

Sensible Medicine ·

2026/07/29

Tamsulosin Deprescribing for Lower Urinary Tract Symptoms in Older Men A Randomized Clinical Trial* Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No TreatmentCost-Effectiveness of Fecal Immunochemical Testing Alone vs Co-Testing With Helicobacter pylori Stool Antigen This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

44:34

This Fortnight in Medicine XXX

Sensible Medicine ·

2026/07/15

Polypill for heart failure with reduced ejection fraction: the POLY-HF randomized trialJohn Mandrola: I am torn on the PolyPill concept This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

37:28

This Fortnight in Medicine XXIX

Sensible Medicine ·

2026/07/01

Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia* Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysisThe Impact of Midodrine on Guideline-Directed Medical Therapy in Patients Admitted With Systolic Heart Failure This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

4:57

Friday Reflection 62: The Ethics of Telling Patients...

Sensible Medicine ·

2026/06/26

TR is an 88-year-old man who is disabled and in chronic pain from spinal stenosis and knee osteoarthritis. He has multiple other medical issues, including coronary artery disease and COPD.He has been through years of treatment for his knees and back, including physical therapy, multiple joint injections, and an in-office procedure for spinal stenosis. He has been on multiple regimens of oral pain medications. He is not interested in surgery (and probably would not be considered a reasonable

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32:16

This Fortnight in Medicine XXVIII

Sensible Medicine ·

2026/06/17

Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults* Prespecified Falsification End Points: Can They Validate True Observational Associations?* Ultrasonography versus Computed Tomography for Suspected NephrolithiasisGLP-1 receptor agonist use and cancer risk in obese nondiabetic adults* Risk for Cancer With Glucagon-Like Peptide-1 Receptor Agonists and Dual Agonists: A Systematic Review and Meta-analysis This is a public episode. If you'd like to discuss this with other subscribers

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33:01

This Fortnight in Medicine XXVII

Sensible Medicine ·

2026/06/03

Reduced Melanoma After Regular Sunscreen Use: Randomized Trial Follow-UpGLP-1 Receptor Agonists or SGLT2 Inhibitors and Nonarteritic Anterior Ischemic Optic Neuropathy* Previously discussed on Fornight XXII: Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

54:35

This Fortnight in Medicine XXVI

Sensible Medicine ·

2026/05/20

Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

en

30:20

This Fortnight in Medicine XXV

Sensible Medicine ·

2026/05/06

Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients* Real-World Effectiveness of Nirmatrelvir–Ritonavir Against Severe Outcomes of COVID-19 in Taiwan: A Nationwide Population-Based Cohort StudyThree Low-Dose Antihypertensive Agents in a Single Pill after Intracerebral Hemorrhage* Effect of Combination Therapy on Adherence Among US Patients Initiating Therapy for Hypertension: a Cohort Study This is a public episode. If you'd like to discuss this with other subscribers or get access

en

147 results

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