Loading...

PODCAST

Talk Python To Me

Michael Kennedy

Talk Python to Me is a weekly podcast for Python developers, data scientists, and AI builders, hosted by developer and entrepreneur Michael Kennedy. We dive deep into the packages, tools, and people shaping Python, from web development and data science to AI and LLMs. If you"re new to Python, you"ll quickly learn the ins and outs of the community by hearing from its leaders. And if you"ve been Pythoning for years, you"ll hear about your favorite

technology

All Episodes

87:46

#565: Tachyon, Python 3.15's Built-in Sampling Profiler

Talk Python To Me ·

2026/10/02

Do you know what's actually slow in your Python app? Or are you guessing? Until now, profiling Python meant a tracing profiler that made your code 2 to 3 times slower. Or a third-party tool that broke with every new release. Python 3.15 fixes that. It ships Tachyon, a sampling profiler built into the standard library. It attaches to live production apps with almost zero overhead. My guests are Pablo Galindo Salgado, CPython core developer and Steering Council member, and László Kiss

en-us

67:52

#564: EVE Online Departs for Python 3

Talk Python To Me ·

2026/09/22

Every ship in EVE Online eventually undocks and leaves the station. This time, it's the whole game. EVE has run on Python 2 since it launched in 2003, all 2.4 million lines of it, on a custom Stackless interpreter that stopped at 3.8 and was archived last year. Destination: Python 3.12. The route runs through 6,500 lines of division that decide who wins a fight, and 100 gigabytes of pickled Python objects that have to survive the jump intact. Kristinn Sigurbergsson was on this show

en-us

70:50

#563: Getting Started with Rust as Python Devs

Talk Python To Me ·

2026/09/16

Lint the entire CPython code base from scratch. It takes 0.3 seconds. Three blinks of an eye.That is ruff, and it is written in Rust. So are Pydantic, Polars, uv, and Granian. Rust shows up in Python three ways: tools that happen to be Rust, libraries Python imports, and servers that run Python inside Rust. This is Rust for Python developers, not Rust experts. Christopher Trudeau is back on Talk Python to discuss Rust and his latest course Up and Running with Rust. The core

en-us

71:09

#562: DuckLake: The Lakehouse That's Just SQL and...

Talk Python To Me ·

2026/09/10

How many files does your query read before it reads any data? On some data lakes, you go through JSON and metadata files first, just to learn which Parquet files matter. DuckLake asks one SQL question instead. The metadata lives in a real database. The data stays in plain Parquet. That's the entire format.Pedro Holanda joined DuckDB in 2018, when it was still a research prototype at CWI. He's the lead DuckLake developer. Guillermo Sanchez Dionis works on DuckLake and the new

en-us

75:47

#561: TonIO, a Multi-threaded Async Runtime for Python

Talk Python To Me ·

2026/09/04

How many cores does your machine have, 10, 18? Your async Python code uses just one of them. That isn't a bug in asyncio. That's the design, and optimizing event loops to be faster by 20% doesn't change it. So Giovanni Barillari started over. Joe is the creator of Granian, the Rust-based server that powers Talk Python. His new project is TonIO, an async runtime written from scratch for free-threaded Python. Real threads, a handful of primitives instead of asyncio's pile of them, and

en-us

62:49

#560: Building a Research OS: From Django to 30,000...

Talk Python To Me ·

2026/08/26

In 2020, a gastroenterologist in Glasgow did the math on his new research study and came up with 30,000 samples, arriving over two years from three cities and a dozen hospitals. He asked around about how researchers keep track of that. The answer was Microsoft Excel. Shaun Chuah had written some HTML by hand in Notepad back in high school and that was about the whole of his programming experience, so he opened the Django tutorial and started reading. Six years later that app is

en-us

67:51

#559: 12 Things You Should (and Shouldn't) Do in AWS

Talk Python To Me ·

2026/08/19

Your site is down. It's 3am. Is it a bug, a bill, or a breach? You can't tell yet, and everyone is watching you find out. Matt Lea has spent fifteen years being the person companies call when an outage is costing them real money per hour, and his whole argument is that everything you'd want in that moment gets decided months earlier, on ordinary afternoons, when someone chose the convenient thing. We walk his top twelve dos and don'ts in AWS - infrastructure as code, IAM roles

en-us

62:13

#558: Hyper-Personal Software with Python

Talk Python To Me ·

2026/08/10

Every company has one. The little internal tool that Jane built back in 2021, and then Jane left. Nobody understands it, nobody will touch it. There are two unwritten rules around it: don't change it, it's working. And if you break it, you bought it. That's dark-matter enterprise software.For every app you can actually see, there are ten of these sitting in the shadows, frozen. Michael Booth thinks that just changed. He read my article on hyper-personal software and ran with it,

en-us

68:00

#557: Security of everything at PyCon 2026

Talk Python To Me ·

2026/08/02

Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this year, that changed. For the first time ever, security got its own dedicated, day-long track, one of just two at the whole conference, sitting right next to AI. And the room was packed to the back wall.On this episode, I'm joined by the three people at the center of it. Seth Larson, Security Developer in Residence at the Python

en-us

64:56

#556: Updates on Django's Async Story

Talk Python To Me ·

2026/07/26

For years, "Django and async" came with an asterisk. The docs themselves warned you off it. Scary performance notes, a story that felt half-finished. Well, that story just got rewritten, literally, and the person who rewrote it is here to tell you why the old framing was wrong.Carlton Gibson is a former Django Fellow, sat on the security team for eight years, and he's on the steering council. On this episode we get into the async topic doc rewrite, what actually remains versus

en-us

64:59

#555: Marimo Pair - A Canvas for Agent + Developers...

Talk Python To Me ·

2026/07/13

Coding agents have gotten really good at one kind of work. You scope a feature, edit some files, run the tests, ship it. It all happens on disk. But that is not how data work feels. You load something, you look at it, you run a cell, you watch how it responds, and you decide the next move from whatever is sitting in memory. And until now, your agent couldn't see any of that. It only saw the files. Never the live state. This episode, that wall comes down. marimo pair drops a

en-us

60:40

#554: Trustworthy AI in Healthcare and Longevity

Talk Python To Me ·

2026/07/10

You ask an AI a question and it answers with total confidence. Most of the time, a confidently wrong answer is just an annoyance. But what if the question is medical, and there's a real patient on the other end? In that world, a hallucination isn't a bug, it's a patient-safety event. Sumit Gundawar is a London-based software engineer who builds the clinical platform for a UK longevity and aesthetic-medicine clinic, and his whole argument is that in high-stakes AI, the model is the

en-us

55:15

#553: All of our tools

Talk Python To Me ·

2026/06/26

This episode is a fun crossover from our Python news and tips podcast, Python Bytes. We have had some big changes over there. Brian Okken has moved on and Calvin Hendryx-Parker has joined the show as the new co-host. To kick off this new era, we decided to do a longer and more personal episode called "All Our Tools". The idea is both of us talk about some of our most useful day-to-day developer and business owner tools that we think you all would find useful. It was so well

en-us

65:08

#552: Astral joins OpenAI

Talk Python To Me ·

2026/06/17

OpenAI just acquired Astral, the company behind uv, Ruff, and ty. And if your first thought was "wait, is uv toast?", you are not alone. But here's the twist Charlie Marsh shared with me: he thinks they may ship more open source at OpenAI than they ever did at Astral. On this episode, we get into the acquisition, the mixed feelings, the future of your favorite Python tools, and what it's like to build right at the center of the AI universe.Episode sponsors Sentry Error

en-us

108:54

#551: Stroll Down Startup Lane - 2026

Talk Python To Me ·

2026/06/11

If you've ever been to PyCon, you know one of the best parts of the expo hall is Startup Row, a stretch of booths where early-stage companies built on Python show off what they're creating. But only attendees get to walk that lane, so let's bring it to everyone. In this episode, we stroll down Startup Row together. We kick things off with the organizers, Jason and Shay, who share the program's origin story going back to Paul Graham and the PSF, plus some surprising stats, including

en-us

62:42

#550: AI Contributions and Maintainer Load in Open...

Talk Python To Me ·

2026/05/30

You wake up, brew the coffee, open GitHub, and there it is. Another pull request on your open source project. Thirteen thousand lines added. No issue filed first. No discussion. Just "here, please review this for me."Over the past year, GitHub activity has spiked roughly twelve times in a few short months, and a huge chunk of that signal is landing on the same small group of maintainers who were already stretched thin. The curl bug bounty got buried under AI-generated noise

en-us

67:00

#549: Great Docs

Talk Python To Me ·

2026/05/25

Your documentation has two audiences now - humans reading the rendered HTML, and AI agents trying to make sense of your library. Rich Iannone and Michael Chow from Posit are back on Talk Python with a brand new Python documentation tool called Great Docs that takes both seriously. Rich is the creator of Great Tables, and before that the R package GT, the man has a serious eye for design, and he's pointed that energy at the Python docs ecosystem. We'll talk about how Great Docs spins

en-us

68:49

#548: Event Sourcing Design Pattern

Talk Python To Me ·

2026/05/11

What if your database worked more like Git? Every change captured as an immutable event you can replay, instead of a single mutating row that quietly forgets its own history. That's event sourcing, and Chris May is back on Talk Python, fresh off our Datastar panel, to walk us through what it actually looks like in Python. We'll cover the core patterns, the libraries to reach for, when not to use it, and why event sourcing turns out to be a surprisingly good fit for AI-assisted

en-us

59:16

#547: Parallel Python at Anyscale with Ray

Talk Python To Me ·

2026/05/06

When OpenAI trained GPT-3, they didn't roll their own orchestration layer. They used Ray, an open source Python framework born out of the same Berkeley research lab lineage that gave us Apache Spark. And here's the twist: Ray was originally built for reinforcement learning research, then quietly faded as RL hit a wall. Until ChatGPT showed up. Suddenly reinforcement learning was back, as the post-training step that turns a raw language model into something genuinely

en-us

63:12

#546: Self hosting apps for Python people

Talk Python To Me ·

2026/04/27

The cloud is convenient until it isn't. You upload your photos, sync your contacts, click through the cookie banners. Then prices go up again or you read about a family that lost their entire Google account over a medical photo sent to a doctor. At some point, the question shifts from "why would I run this myself?" to "why aren't I?" My guest this week is Alex Kretzschmar, head of DevRel at Tailscale, longtime host of the Self-Hosted podcast, and co-founder of Linuxserver.io. We

en-us

564 results

Similar Podcasts

Lead With AI

Tamara Nall

The Automated Daily

TrendTeller

My Weird Prompts

Daniel Rosehill

LessWrong (Curated & Popular)

LessWrong

脈報

思思主播