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PODCAST

What"s Up Docs?

In this BBC Radio 4 podcast, Drs Chris and Xand van Tulleken are on a mission to help us take better care of ourselves.Although they are identical twins, Chris and Xand are very different and they never stop thinking and arguing about science and health. They want to lead healthy, happy lives and as doctors, they want this for everyone. Yet they tussle over how best to get there.When it comes to looking after our own health, it can be confusing. Medicine and science produce amazing new treatments

health & fitness nature

All Episodes

15:57

Doctors' Notes: Endometriosis

What"s Up Docs? ·

2026/02/24

Chris and Xand continue their conversation about endometriosis with Dr Chi Eziefula, Associate Professor in Global Health and Infection at Brighton and Sussex Medical School.The doctors want to know what the deeper biology of endometriosis is, how general attitudes around women’s health impact the time it takes to be diagnosed with conditions, and if we are seeing any change in the research and social landscape surrounding endometriosis. They also explore how medical training impacts doctors'

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29:14

How can we better understand endometriosis?

What"s Up Docs? ·

2026/02/24

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.In this episode, Chris and Xand dive into endometriosis, a condition that occurs when cells similar to the ones in the lining of the womb (uterus) grow in other areas of the body. It affects around one in ten women of reproductive age, often causing severe pain, mental health issues and in some cases, it can result in

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26:46

Doctors' Notes: Immune Health

What"s Up Docs? ·

2026/02/17

Chris and Xand continue their conversation about immune health with Prof Dan Davis, Head of Life Sciences and Professor of Immunology at Imperial College London.The doctors want to know more about the deeper biology of the immune system. Is it true that a bit of stress prevents infection, while chronic stress is detrimental to your immune system? Why does intense exercise drop the immune response? They also examine autoimmune diseases, what they are and what they do to the body.If you’d like to

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29:00

Does your immune system need boosting?

What"s Up Docs? ·

2026/02/17

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.What defines a well-functioning immune system, and why are some people seemingly "immune" to everything while others catch every cold? In this episode, Chris and Xand dive into the complex mechanics of immunology. They tackle the controversial trend of "immune boosting" and discuss the delicate balance between under-active and

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20:22

Doctors' Notes: Kissing

What"s Up Docs? ·

2026/02/10

Chris and Xand dig deeper into the evolution of kissing. They ask what first drew our guest into this unusual area of research, why evidence that humans and Neanderthals kissed is so significant, and why it’s so challenging to explain why kissing developed in the first place.If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at whatsupdocs@bbc.co.uk or Whatsapp on 08000 665 123.Presenters: Drs Chris and Xand van TullekenGuest: Dr Matilda

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28:30

Why do we kiss?

What"s Up Docs? ·

2026/02/10

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken try to get to the bottom of the ideas shaping our health and wellbeing. In this Valentine’s Day-themed episode, they turn their attention to kissing. Why do humans kiss, how did it evolve, and does it offer any biological advantage? They also explore the meaning behind different types of kisses and whether kissing is truly universal among humans – and what it means if it isn’t.To help them untangle

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24:04

Doctors' Notes: Focus

What"s Up Docs? ·

2026/02/03

Drs Chris and Xand continue their conversation about focus with Duncan Astle, Professor of Neuroinformatics at the Department of Psychiatry at Cambridge University.Chris and Xand want to know what the impact of having ADHD is, whether a diagnosis can help and if it can predict anything, the neurology and evolutionary explanations for ADHD, and which interventions are currently available. They also explore some controversial ways of improving focus and hear Dr Astle’s personal and clinical

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28:38

How can you improve your focus?

What"s Up Docs? ·

2026/02/03

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.In this episode, Chris and Xand dive into focus and how it can be improved. How do focus and attention work? Are there different types of attention? What impacts your ability to focus? Is social media ruining your focus? How can you improve? They explore the neurology of focus and attention, why you might find it difficult to

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3:42

Daily Dose: Laughter

What"s Up Docs? ·

2026/01/30

In this Daily Dose, Chris and Xand return to their episode on laughter with Professor Sophie Scott CBE, a leading expert in the neuroscience of laughter, from University College London. Sophie explained how laughter is a positive, evolutionary trait that we all go on a journey to understand as we grow up. Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed on BBC Sounds, alongside all the

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3:16

Daily Dose: Core Strength

What"s Up Docs? ·

2026/01/29

In this Daily Dose, Chris and Xand return to their episode on core strength with physiotherapist James Moore. James highlighted why exercising our core can help us live long and strong, but doesn’t have to mean hitting the gym hard.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed on BBC Sounds, alongside all the main episodes of the podcast.

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4:10

Daily Dose: Fibre

What"s Up Docs? ·

2026/01/28

In this Daily Dose, Chris and Xand return to their episode on fibre with Dr Deirdre Tobias. Deirdre outlined why fibre is important for our diets and where we should be getting it from.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed on BBC Sounds, alongside all the main episodes of the podcast.

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25:50

Doctors' Notes: Diet

What"s Up Docs? ·

2026/01/27

Drs Chris and Xand continue their conversation about food with Professor of Psychology Ashley Gearhardt. Drawing on her clinical experience, they explore what it means to live with food addiction and how shame and stigma make it harder to talk openly, seek help, or make changes. They also explore how Ashley came to study food addiction, and the links between industrial processing of food and tobacco.Presenters: Drs Chris and Xand van TullekenGuest: Professor Ashley Gearhardt Researcher: Samara

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28:52

How can we sustain a healthy diet?

What"s Up Docs? ·

2026/01/27

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.In this episode, Chris and Xand turn their attention to food. It’s January, and many of us have resolved to “eat better” but why does it so often feel like an uphill battle? Why do we crave certain foods and not others? And what does a genuinely healthy relationship with food look like?They explore the science behind how our

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4:38

Daily Dose: Fresh Breath

What"s Up Docs? ·

2026/01/26

In this Daily Dose, Drs Chris and Xand return to their episode on fresh breath with Dr Praveen Sharma. Praveen walked the docs through the best way to take care of our teeth and how we should be thinking about our oral health.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed on BBC Sounds, alongside all the main episodes of the podcast.

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3:54

Daily Dose: Saying 'No'

What"s Up Docs? ·

2026/01/23

In this Daily Dose, Chris and Xand return to their episode on the power of saying no, with Dr Sunita Sah from Cornell University. Sunita had a fantastic point on how saying no is linked to our values - and how we can figure out what our values are.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed on BBC Sounds, alongside all the main episodes of the podcast.

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5:11

Daily Dose: Backs

What"s Up Docs? ·

2026/01/22

In this Daily Dose, Chris and Xand return to their episode on backs with Dr Mindy Cairns, Specialist Musculoskeletal Physiotherapist and Associate Professor at the University of Hertfordshire. Mindy offered some excellent insight into fear avoidance when it comes to back pain, and why we perhaps don’t need to be a fearful as we may think.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed

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4:55

Daily Dose: Protein

What"s Up Docs? ·

2026/01/21

In this Daily Dose, Chris and Xand are return to their episode on protein with Nita Forouhi, Professor of Population Health and Nutrition at the University of Cambridge. Nita had a very clear message - get your protein from wholefoods, rather than supplements.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs? feed on BBC Sounds, alongside all the main episodes of the podcast.

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21:04

Doctors' Notes: Exercise

What"s Up Docs? ·

2026/01/20

Chris and Xand continue their conversation about exercise with Dr Jo Blodgett, Senior Research Fellow at the Institute of Sport, Exercise and Health at University College in London. She’s a life-course epidemiologist whose work focuses on how movement across the whole 24-hour day shapes population health.They talk to Jo about her own sporting background as a semi-professional national league footballer, the impact of the menstrual cycle on sporting performance and the best way to approach exercise

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28:53

How much exercise should you do?

What"s Up Docs? ·

2026/01/20

Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.In this episode, Chris and Xand explore the role and impact of exercise on our bodies and mood. Is going to the gym three times a week the best way of keeping fit? Or should you spread out your activity in shorter bursts throughout the day? They also discover which one of the brothers is ‘an active couch potato’ and why you

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4:03

Daily Dose: Nails

What"s Up Docs? ·

2026/01/19

In this Daily Dose, Chris and Xand return to their episode on nails with Dr Yusur Al-Nuaimi, Consultant Dermatologist at the Royal Devon and Exeter Hospital and Clinical Lead for the British Hair and Nail Society. Yusur highlighted how our nails have developed to optimize human function and are deeply rooted without our evolutionary history.Daily Doses of expert wisdom from previous episodes will be dropping each weekday throughout January (except Tuesdays). You'll find them in the What’s Up Docs

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