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PODCAST

Raising Health

Andreessen Horowitz, a16z Bio + Health

A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vineeta Agarwala, Julie Yoo, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg Verdine, Fei-Fei Li, and Suchi Saria, as they explore the

science life sciences

All Episodes

00:27:53

CVS Health: Building Healthcare’s Consumer Platform

Raising Health ·

2025/11/10

Josh Weiner left Meta to return to CVS Health with two painful realizations: consumers don't manage their health—they expect it, and the healthcare market fundamentally violates every principle of economics. In this conversation with a16z's Julie Yoo, the CVS Senior VP explains why 50% of Americans can't afford a healthcare emergency, how CVS is becoming a platform to solve structural healthcare problems, and why the future depends on consumers finally controlling their own health

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00:47:28

Dyno Therapeutics: Empowering Patients with Genetic...

Raising Health ·

2025/11/07

For the first time in human history, we can diagnose thousands of genetic diseases—often for under $1,000—but we still can't treat most of them. The problem isn't understanding what's broken; it's delivering the fix to the right cells.Eric Kelsic, CEO of Dyno Therapeutics, joins a16z's Jorge Conde to explain how AI-designed protein shells are solving gene therapy's delivery crisis. They explore why Huntington's patients can now get 15 extra years of healthy life, how Dyno inverted the liver-to-brain

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00:41:16

Value-Based Oncology at Scale: Inside Thyme Care

Raising Health ·

2025/09/29

Cancer care in the U.S. costs over $250 billion each year, and nearly 2 million Americans receive a new diagnosis annually, yet too often the journey begins with silence: no call, no plan, no guide.In this episode, a16z’s Vineeta Agarwala and Jay Rughani talk with Thyme Care leaders Robin Shah (cofounder and CEO), Bobby Green, MD (president and CMO), and Brad Diephuis, MD (president and COO) about rebuilding oncology around the patient. They cover where the system breaks, how navigation plus

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00:28:05

The Consumer Becomes the Payor: How ICHRA Unlocks a...

Raising Health ·

2025/08/06

In this episode, Julie Yoo and Jay Rughani are joined by Thatch cofounders Chris Ellis and Adam Stevenson to explore why ICHRA—a more recent policy innovation—might quietly revolutionize employer-sponsored health benefits. Unpacking the surprising history of how U.S. healthcare became entangled with employment, they make the case for a defined-contribution future that mirrors the rise of the 401(k) and HSA. Tailored especially for today’s distributed and fast-moving workforce, ICHRA allows employers

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00:22:32

Engaging the Unengaged at Home with Max Cohen and...

Raising Health ·

2025/07/22

In this episode, Sprinter Health co-founders Max Cohen and Cameron Behar sit down with Julie Yoo to unpack how their home-based care model reaches underserved populations and reintegrates “the unengaged” into the healthcare system. From starting with blood draws in living rooms to scaling a high-complexity, tech-enabled logistics platform, they share how operations, empathy, and human connection power their success. The duo reflects on the constraints and regulatory nuance of healthcare, revealing

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00:19:53

Streamlining the Patient Referrals Chain with Trey...

Raising Health ·

2025/06/20

In this episode, Tennr cofounder and CEO Trey Holterman sits down with a16z’s David Haber and Jay Rughani to unpack one of healthcare’s most overlooked pain points: patient referral logistics. When a patient is referred to a specialist and told that the specialist will follow up with them, what happens next? A convoluted system sometimes involving dozens of staff and multiple portals, all of which may or may not result in the specialist actually following up. Trey shares how Tennr leverages AI to

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00:23:23

From Chaos to Clarity in Data with Malinka Walaliyadde

Raising Health ·

2025/06/10

What if one of healthcare’s most complex administrative challenges—revenue cycle management—was reframed as a data science problem? In this episode, Malinka Walaliyadde, cofounder and CEO of AKASA, joins Julie Yoo to unpack how large language models have the potential to transform hospital revenue by automating highly nuanced coding and billing workflows. Malinka discusses how AI is finally making it possible to extract simplicity from a sea of clinical complexity and unstructured data, simplifying

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00:42:42

Superaging with Eric Topol

Raising Health ·

2025/05/27

What if we stopped trying to cure disease and started preventing it instead? In this episode, Eric Topol, founder and director of the Scripps Research Translational Institute and a cardiologist, scientist, and author, joins a16z general partner Vijay Pande to unpack the future of aging, prevention, and precision health—as explored in Eric's new book, Super Agers: An Evidence-Based Approach to Longevity.Together, they discuss AI-driven risk prediction and next-gen immunotherapies — a roadmap for how

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00:24:46

Fueling Innovation with Data with Arif Nathoo

Raising Health ·

2025/05/13

Arif Nathoo, cofounder and CEO of Komodo Health, joins Jorge Conde and Jay Rughani to explore the transformative potential of healthcare data in reshaping biotech and healthcare innovation. Arif reflects on a decade-long journey of unlocking the power of fragmented healthcare data, delving into Komodo Health’s “full-stack thesis” — a strategy that combines rich datasets, advanced analytics, and AI to enable life sciences companies, payors, and providers to make better decisions at scale.Together,

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00:33:32

The Paradox of U.S. Healthcare with Marc Andreessen

Raising Health ·

2025/04/29

Join a16z general partners Marc Andreessen, Julie Yoo, and Vijay Pande for an incisive exploration of what's driving—and stalling—transformation in healthcare. With the industry now consuming nearly 20% of U.S. GDP yet delivering poor outcomes relative to other developed countries, is technology the remedy or a red herring?This episode, cross-posted with the a16z podcast, dissects the inertia holding healthcare back, from regulatory bottlenecks to misaligned incentives, while offering actionable

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00:26:00

The (Epic) Arc of a Patient Journey with Seth Hain

Raising Health ·

2025/04/15

Seth Hain, SVP of R&D at Epic, joins a16z Bio + Health general partner Julie Yoo to explore technology in healthcare. Reflecting on over two decades of industry shifts, Seth shares how Epic has transitioned from enabling integrated systems within health systems to driving cross-ecosystem collaboration and rapid innovations like generative AI.They also discuss orchestration of patient care across diverse settings, the transformative impact of AI on clinical workflows, and whether "electronic health

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00:26:01

Building for the Healthcare Consumer with Elliot Cohen

Raising Health ·

2025/04/01

Elliot Cohen, cofounder of PillPack, joins Julie Yoo, a16z Bio + Health general partner. Together, they discuss Elliot's experience designing and building a consumer-first pharmacy alongside TJ Parker.Elliot's journey with PillPack began when he noticed his father struggling with a mail-order pharmacy that couldn’t get the simplest thing right: the correct version of a pill.Elliot shares the nitty-gritty of building a consumer-centric business in healthcare, including how they had to adapt CSV files

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00:25:40

Scaling Mental Health Access through AI with Neil...

Raising Health ·

2025/03/11

In this episode, Slingshot AI cofounders Daniel Cahn and Neil Parikh join a16z Bio + Health general partner Julie Yoo to explore how their mission to transform mental health care with AI took shape. Drawing from their unique journeys—Daniel as the son of a psychologist and Neil as a former medical student-turned-entrepreneur—they discuss the challenges and opportunities of building AI models to model psychological processes and how this could expand access for subclinical mental health

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00:23:33

An Ironman Suit for Doctors with Muthu Alagappan

Raising Health ·

2025/02/25

Dr. Muthu Alagappan, MD, founder and CEO of Counsel Health, joins Julie Yoo, a16z Bio + Health general partner, to dive deep into the company's vision for revolutionizing healthcare through AI-powered asynchronous care. Together, they unpack how Counsel enables on-demand access to real doctors for instant medical guidance, lessening patient reliance on Google and alleviating system inefficiencies and physician burn-out. Dr. Alagappan also explores the duo of efficiency and scale that large language

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00:30:03

Voice AI: Solving Healthcare's Workforce Challenges...

Raising Health ·

2025/02/11

Ankit Jain, CEO and cofounder of Infinitus Systems, Inc, joins Julie Yoo, a16z Bio + Health general partner, to discuss Infinitus's work in solving one of healthcare's most pressing challenges: workforce shortages. Leveraging LLMs and AI voice agents, Infinitus automates repetitive tasks, such as benefits verification and prior authorization, freeing up human talent for higher-value roles. Ankit reflects on the company’s journey—from early proof-of-concept calls to scaling over five million

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00:24:53

Transforming Clinical Trials with Alexander Saint-Amand

Raising Health ·

2025/01/28

Alexander Saint-Amand, cofounder and CEO of Topography, reflects on his journey from leading Gerson Lehrman Group (GLG), a pioneer in expert networks, to tackling systemic barriers in clinical trials at his current company, Topography. Inspired by personal experiences, Alexander’s mission centers on democratizing access to clinical research by transforming community-based practices into thriving hubs for trials. Alongside a16z Bio + Health general partner Julie Yoo, he discusses the pervasive

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00:33:45

Scaling Medicaid Innovation with Afia Asamoah, Rajaie...

Raising Health ·

2025/01/14

Rajaie Batniji, MD, PhD, Afia Asamoah, JD, and Sanjay Basu, MD, PhD, cofounders of Waymark, join Vineeta Agarwala, MD, PhD, a16z Bio + Health general partner, to discuss their transformative approach to Medicaid care delivery. This episode dives into their rising risk signal prediction framework, where cutting-edge machine learning predicts patient needs and enables community-based care teams to reduce preventable ER visits and improve health outcomes at scale. The team recently published their

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00:24:36

Super Staffing in Healthcare with Munjal Shah

Raising Health ·

2025/01/09

Hippocratic AI cofounder and CEO Munjal Shah joins a16z Bio + Health general partner Julie Yoo to explore the incredible potential of generative AI in transforming healthcare delivery. Together, they discuss the emerging "voice renaissance" in healthcare, the nuances of designing safe and empathetic AI interactions, and how Hippocratic AI is addressing safety concerns with innovations like multi-LLM architecture and rigorous training with thousands of nurses. This episode also discusses a shift

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00:23:26

Lessons from Healthcare Infrastructure Pioneers with...

Raising Health ·

2024/12/30

Jeff Margolis, founder of TriZetto, joins Julie Yoo, a16z Bio + Health general partner, to share the journey of building an iconic company in healthcare infrastructure. From the early days of managed care to creating a three-pronged platform uniting computing power, software, and data analytics, Jeff reflects on TriZetto’s groundbreaking model that reshaped payer-provider transactions and set industry standards. Together, they also delve into the strategic importance of scaling through acquisitions,

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00:23:08

Rare Disease, Big Impact with Matt Wilsey

Raising Health ·

2024/12/10

In this episode, Matt Wilsey joins Jorge Conde to share the profound personal story of his daughter Grace's diagnosis with NGLY1 deficiency and how it catalyzed his journey to founding a biotech startup, Grace Science, aimed at developing a cure for his daughter’s condition.Matt emphasizes the importance of strategic partnerships, like his collaboration with Nobel laureate Carolyn Bertozzi, and sheds light on the search for gene therapies for rare diseases. Check out our previous episode with

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188 results

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