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PODCAST

Longevity Optimization with Kayla Barnes-Lentz

Kayla Barnes-Lentz

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

health & fitness

All Episodes

01:54:54

Dr. Aimie Apigian, MD: The Biology of Trauma +...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/02/19

Longevity isn’t just workouts, supplements, and recovery tools, it starts with nervous system health. In this episode, Dr. Aimie Apigian explains what trauma actually is (not a label, but a measurable physiological response), how the body shifts from stress into overwhelm, and why “pushing through” often turns into years of avoidance, numbing, and hidden internal strain.She breaks down the biology behind the trauma response, including the role of adrenaline, cortisol timing, and how mitochondrial

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00:18:48

I Became the First Woman in the World to Test Her...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/02/14

For the first time in history, ovarian biological age can be measured, and I became the first woman in the world to take the test.Until now, women have had no real way to understand how their ovaries are aging beyond rough estimates like AMH. But this new machine-learning algorithm, trained on over 40,000 real women across different life stages, analyzes hormone biomarkers, body composition, and reproductive history to estimate ovarian age relative to chronological age.This is a massive step forward

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00:58:49

Cynthia Thurlow, NP: Perimenopause, Insulin...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/02/12

Perimenopause is not just about hormones, it’s a metabolic transition that affects insulin sensitivity, gut health, stress tolerance, and long-term disease risk.In this episode, Cynthia Thurlow, board-certified nurse practitioner and functional medicine expert, explains how women’s metabolism changes in midlife and why insulin resistance, poor stress resilience, and gut dysfunction often appear years before menopause.She breaks down how perimenopause can begin earlier than most women expect, why

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02:39:42

Dr. Chris Masterjohn, PhD - Mitochondria,...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/02/05

When cellular energy production is impaired, no diet, supplement, or health protocol can work as intended.In this episode, Dr. Chris Masterjohn, nutrition scientist and expert in micronutrients and metabolism, explains why mitochondrial function is the limiting factor behind stalled progress, persistent fatigue, and supplements that stop working over time.He breaks down why vitamin D supplementation often creates new problems when it is taken without proper nutrient balance, how high doses can

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00:49:13

Dr. Jessica Shepherd, MD – Menopause, Hormone Therapy...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/01/29

In this episode, Dr. Jessica Shepard, board-certified OB/GYN and Chief Medical Officer of Hers, shares that the FDA just removed the black box warning on hormone replacement therapy after 23 years. We discuss what actually happened with the WHI study that created all the fear around estrogen and breast cancer, and why the research never actually supported that narrative.Dr. Shepard explains why you shouldn't wait until menopause to start the HRT conversation and how starting in your

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01:09:08

Dr. Khanh Nguyen - The Blood Swap: Why Doctors Are...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/01/22

What if your blood is what’s making you sick and the key to reversing it is removing it?In this episode, I sit down with Dr. Khanh Nguyen, a regenerative and anti-aging physician, to explore therapeutic plasma exchange and the rising use of young plasma. We talk detox, autoimmune disease, aging, peptides, and why your blood might be holding you back.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and

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01:01:40

Dr. Ann Shippy, MD - The Fertility Alarm: Why 1 in 31...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/01/15

Is your environment silently sabotaging your fertility? Dr. Ann Shippy joins the show to reveal how hidden toxins, mold, and overlooked cellular damage may be accelerating ovarian aging and how to reclaim your fertility before it’s too late. From infertility misdiagnoses to rising autism rates, we dive deep into the tests most doctors never run, and the real impact your body’s toxic load has on future generations. Kayla's social + website:Instagram: kaylabarnesTikTok: femalelongevityTwitter:

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01:15:40

Ashley Koff, RD - Dietitian Reveals: The Hormone...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/01/08

Ashley Koff is a registered dietitian and author who spent 20 years discovering that weight and health aren't separate issues, they're connected through "weight health hormones." After her own struggles with restrictive eating despite doing everything "right," a functional medicine doctor helped her understand what was actually broken, and that was, her body's natural hormone function.In this episode, Ashley explains why GLP-1 medications like Ozempic work, who

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01:38:37

Dr. Will Bulsiewicz, MD - The #1 Nutrient for...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/01/01

In this video, Dr. Will Bulsiewicz shares his transformation from an overweight, depressed gastroenterologist to a gut health expert after meeting his now-wife changed his entire approach to food. He reveals why 95% of Americans are fiber deficient and how this single nutrient could be the key to longevity. Dr. B breaks down the science of the gut microbiome, explains why hyperpalatable foods force us to overeat 500 extra calories per day, and shares actionable strategies for rebuilding your gut

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00:25:04

How to Make 2026 Your Healthiest Year Ever (Complete...

Longevity Optimization with Kayla Barnes-Lentz ·

2026/01/01

Women don’t fail January — January fails women. Nearly 80% of New Year health goals are abandoned within weeks, not because of discipline, but because most plans ignore female biology. That’s why I created the 30-Day Female Longevity Challenge — a physiology-first way to prepare calmly and build health that actually lasts. Save $50 with code 2026. https://kayla-barnes-lentz.circle.so/checkout/female-longevity-challenge-2026?coupon_code=2026When you join, you also get one full year access to my

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01:16:02

Dr. Sarah E. Hill, PhD - PMS Expert: Get Through Your...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/12/18

In this conversation, Kayla sits down with Dr. Sarah E. Hill, PhD to talk about the science behind PMS, cycle syncing, and why most health advice completely fails women. Dr. Hill explains the three main causes of PMS symptoms, natural hormonal shifts, one-size-fits-all protocols designed for men, and lack of cellular resilience.Join the most comprehensive female-specific community for health and longevity optimization. After over a decade dedicated to human performance and women’s health, I created

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01:52:54

Deanna Minich, PhD - Doctor Shares: 5 Superfoods...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/12/11

For years, functional medicine has focused on lab results and supplement protocols. Dr. Deanna Minich knows there's a deeper layer most practitioners miss. As a nutrition scientist who worked under Dr. Jeffrey Bland and educated for the Institute for Functional Medicine, she's witnessed how artificial light at night disrupts women's hormones more than almost any other factor, yet it's completely ignored.In this episode, Dr. Minich reveals why 85% of people are Omega-3 deficient

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00:53:45

Aly Cohen, MD - The Autoimmune Epidemic: Why Everyone...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/12/04

Everyday “healthy” choices might be silently rewiring your immune system—from canned soup and tap water to perfume, makeup, and even your couch—while autoimmune diseases quietly explode, especially in women. In this gripping conversation, Dr. Aly Cohen reveals how under-regulated chemicals, hidden toxins, and epigenetic changes may be driving the autoimmune epidemic, but also how strategic swaps, smarter water, food, air, and a 4-A framework can actually change the destiny of your health. If you’ve

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01:02:59

Dr Karan Rajan - Gut Surgeon: STOP Probiotics (Heal...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/11/27

In this episode, Kayla sits down with Dr. Karan Rajan, who is one of the most followed medical professionals on social media, and he breaks down the gut microbiome like you've never heard before. If you've ever felt bloated after eating fiber, tried keto and felt amazing temporarily, or wondered why your "clean" diet isn't delivering results, this episode is for you.They talk about why fiber is non-negotiable fuel for your gut bacteria, how to gradually increase intake from 10g

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00:56:10

Dr Tania Elliot - Healing Allergies and Histamine

Longevity Optimization with Kayla Barnes-Lentz ·

2025/11/20

Your home could be triggering your allergies and nobody's checking. Dr. Tania Elliott sees patients struggling with reactions that disappear before they can get to the doctor's office. That's why she started doing virtual home tours to find what's really causing the problem.In this episode, Dr. Elliott explains why that new couch smell is actually toxic, how synthetic candles mess with your hormones, and why our obsession with being too clean backfired into an allergy epidemic. She digs into Mast

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01:03:38

Lily Nichols, RDN - Fertility Nutrition: These Diet...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/11/13

Are you planning to get pregnant, currently pregnant, or postpartum? This conversation with dietitian Lily Nichols will change how you think about nutrition during these critical life stages.Lily reveals that over 90% of women have nutrient deficiencies that directly impact fertility, pregnancy outcomes, and postpartum recovery. Most women have no idea they're lacking essential nutrients like protein, iron, zinc, B12, choline, and vitamin A until it's already affecting their hormones and

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01:13:58

Dr Jessica Peatross, MD: This Hidden Toxin Causes Bad...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/11/06

Are you dealing with unexplained fatigue, hormonal imbalances, brain fog, or chronic inflammation that doctors can't figure out? In this episode, Dr. Jess Peatross explains why so many people are sick with "mystery symptoms" that doctors can't solve. She breaks down the toxins and infections making you sick, how to test for them properly, and her step-by-step "Kill Bind Sweat" detox method. So, if you've been told "it's all in your head" or that your

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01:08:28

Dr Darshan Shah: The Early Death Metric: This Blood...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/10/30

When a top surgeon faces his own health collapse, he’s forced to question everything he’s ever believed about medicine. In this gripping conversation, Dr. Darshan Shah reveals how hitting rock bottom led him to uncover the true keys to longevity — from biomarker mastery and advanced testing to the future of AI-driven health and gene therapy. This episode will make you rethink what it means to live — and how long you can do it.Join the most comprehensive female-specific community for health and

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01:46:45

Dr. Christopher Davis - Heart Doctor: Low-Fat Foods...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/10/23

Most people think heart disease is just about cholesterol. But what if the real issue is in your genes, your environment, and even your daily stress?In this episode, I’m joined by Dr. Christopher Davis, a triple board-certified interventional cardiologist who’s redefining what it means to take care of your heart. After years of performing stent procedures, he realized the conventional system was only treating symptoms, not causes. So he made a bold shift from reactive cardiology to a root-cause

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01:20:52

Jim Kwik - This 6-Second Trick Helps You Remember...

Longevity Optimization with Kayla Barnes-Lentz ·

2025/10/16

Brain coach Jim Kwik went from being called “the boy with the broken brain” to teaching millions how to unlock their limitless potential. In this episode, he reveals the simple shifts that supercharge focus, memory, and learning speed—helping you read faster, think clearer, and retain more.Discover why mindset, motivation, and method are the three keys to peak mental performance, and how to apply them in everyday life. Whether you’re an entrepreneur or lifelong learner, this conversation will change

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148 results

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