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PODCAST

The ImmunoVerse™

Moffitt Cancer Center

The ImmunoVerse™ is a monthly podcast exploring the past, present and future of immunotherapy and delving into every intricacy of the body"s immune system. Hosted by Moffitt Cancer Center President and CEO, Dr. Patrick Hwu, each episode highlights the trailblazing visionaries who are pushing boundaries in this ever-evolving, world-changing field.

health & fitness life sciences

All Episodes

24:05

LIVE from the 2025 SITC Annual Meeting, ft. Sandra...

The ImmunoVerse™ ·

2025/11/09

Dr. Patrick Hwu welcomes Dr. Sandra Demaria, Professor of Radiation Oncology and Pathology at Weill Cornell Medicine and a global leader in cancer immunology. Dr. Demaria shares her pioneering research demonstrating how radiotherapy can transform tumors unresponsive to immune checkpoint inhibitors into responsive ones—a discovery that has reshaped cancer treatment strategies worldwide.Recorded live from the 2025 SITC Annual Meeting, this episode highlights the emerging science shaping the

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20:43

From Cytokines to Checkpoint Blockade: Advancing...

The ImmunoVerse™ ·

2025/10/23

Dr. Patrick Hwu welcomes Dr. Mario Sznol, professor of medicine at Yale School of Medicine and co-director of the Cancer Immunology Program at Yale Cancer Center. Dr. Sznol shares his journey from early work with high-dose interleukin-2 at the NCI to leading pivotal trials in checkpoint blockade and combination immunotherapies. He discusses the science behind cytokines, immune checkpoints, bispecific antibodies, and T-cell therapies, along with strategies for managing immune-related toxicities. Dr

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21:10

CAR T Therapy and the Future of Cellular Treatments,...

The ImmunoVerse™ ·

2025/09/25

Dr. Patrick Hwu welcomes Dr. Fred Locke, chair of Blood and Marrow Transplant and Cellular Immunotherapy at Moffitt Cancer Center. Dr. Locke shares his personal and professional journey into CAR T-cell therapy, shaped in part by his own father’s cancer battle. A leader in pivotal clinical trials, Dr. Locke explains how engineered T cells are transforming lymphoma treatment — offering durable, sometimes curative responses. He discusses the science behind CAR T-cell manufacturing, trial design and its

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24:49

Hot vs. Cold Tumors: Decoding the Tumor...

The ImmunoVerse™ ·

2025/08/28

Dr. Patrick Hwu sits down with Dr. Thomas Gajewski, a leader in tumor immunology at the University of Chicago. Dr. Gajewski discusses his pioneering work defining “hot” versus “cold” tumors — an insight that transformed how immunotherapists understand tumor response. The conversation dives into how the tumor microenvironment, patient genetics and even the gut microbiome shape immune activity in cancer. His work continues to drive strategies to turn cold tumors into responsive ones, giving new hope

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22:32

Targeting KRAS: A New Era for Pancreatic Cancer, ft....

The ImmunoVerse™ ·

2025/07/31

Dr. Patrick Hwu welcomes Dr. Elizabeth Jaffee of Johns Hopkins, a renowned leader in cancer immunotherapy. Dr. Jaffee shares the personal and scientific journey that led her to tackle one of oncology’s toughest challenges: pancreatic cancer. From her early fascination with virology to pioneering the use of genetically modified tumor vaccines, she has pushed the boundaries of what’s possible in cancer prevention and treatment. What You’ll Learn from Dr. Jaffee The role of KRAS mutations in

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22:27

Skepticism to Standard of Care: The T-Cell Journey,...

The ImmunoVerse™ ·

2025/06/26

Host Dr. Patrick Hwu sits down with immunotherapy pioneer Dr. James Mulé to discuss the origins and evolution of T cell therapies, groundbreaking discoveries at the NCI, and the translation of research to patient care at Moffitt Cancer Center.

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23:18

The T-Cell Transformation, ft. Dr. Philip Greenberg

The ImmunoVerse™ ·

2025/05/22

Host Dr. Patrick Hwu sits down with trailblazing immunologist Dr. Phil Greenberg of Fred Hutchinson Cancer Center to explore how engineered T cells are revolutionizing cancer treatment. From early experiments in synthetic biology to today's clinical breakthroughs, Dr. Greenberg shares his decades-long journey to harness and rewire the immune system, turning obstacles into opportunities and transforming science fiction into standard of care.

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24:54

Origins of Cancer Immunotherapy, ft. Dr. Steven...

The ImmunoVerse™ ·

2025/04/24

In the premiere episode of The ImmunoVerse, host Dr. Patrick Hwu sits down with pioneering physician-scientist Dr. Steven A. Rosenberg, Chief of Surgery Branch at the National Cancer Institute. Together, they explore the roots of Dr. Rosenberg’s fascination with the immune system, tracing his remarkable journey from early scientific curiosity to the groundbreaking immunology discoveries that have reshaped cancer treatment.

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0:30

The ImmunoVerse™ - Trailer

The ImmunoVerse™ ·

2025/04/05

Welcome to The ImmunoVerse™, a podcast exploring the past, present, and future of immunotherapy. In each episode, join Dr. Patrick Hwu as he sits with pioneering experts who are shaping the future of cancer treatment—uncovering breakthroughs, challenges, and the science driving this life-saving innovation. Don’t miss out—subscribe to The ImmunoVerse™ now and listen on your favorite podcast platforms!

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