Arjun Khemani Podcast

32:48

Aubrey de Grey: Longevity Escape Velocity, SENS & the...

Arjun Khemani Podcast ·

2026/10/01

My conversation with Aubrey de Grey, a biomedical gerontologist, founder of the LEV Foundation, and author of Ending Aging.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 - SENS vs. the Hallmarks of Aging2:47 - The Robust Mouse Rejuvenation experiment5:48 - Is SENS falsifiable?7:12 - CMLase and extracellular matrix damage10:28 - VEGF and extending lifespan in mice11:37 - Why longevity studies rarely

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56:25

Michael Levin: Bioelectricity, Aging, and the Future...

Arjun Khemani Podcast ·

2026/09/21

My conversation with Michael Levin, a biologist at Tufts University whose research explores bioelectricity, regeneration, morphogenesis, and how cells collectively process information to build and repair bodies.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 - Causes and downstream effects of aging3:31 - Bioelectric patterns and memory in

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67:09

Karl Pfleger: The Road to Solving Aging

Arjun Khemani Podcast ·

2026/08/08

Karl Pfleger is the founder of agingbiotech.info and an investor in several rejuvenation startups.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 - Why lifespan is the wrong metric for aging progress7:28 - Is the hallmarks of aging expanding a problem?11:36 - Structures vs. processes: the key distinction in aging targets16:14 - Why Karl

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69:14

David D. Friedman: Death, Taxes, and Other Solvable...

Arjun Khemani Podcast ·

2026/07/01

David D. Friedman is an anarcho-capitalist economist. He is the author of The Machinery of Freedom, Future Imperfect, and several other books. Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 – The economics of longevity8:05 – Epigenetic reprogramming12:37 – Overpopulation and the “ultimate resource”16:33 – Fluid vs. crystallized

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82:48

Sean Bowe and Dev Ojha: Architecture of Freedom

Arjun Khemani Podcast ·

2026/04/04

Sean Bowe is a core cryptographer and engineer who played a major role in building Zcash’s technology.Dev Ojha, also a cryptographer, is the founder of Osmosis. He is now working on helping Zcash scale and go post quantum.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 - Why Dev’s working on Zcash12:24 - AI is surveillance’s ultimate

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101:20

Sean Bowe and Jack Grigg: Encrypted Money at...

Arjun Khemani Podcast ·

2025/10/11

Sean Bowe and Jack Grigg aka str4d are both cryptographic engineers working on the Zcash protocol. Sean’s latest project is Tachyon, intended to bring encrypted money into the hands of 8 billion people. Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 - Project Tachyon10:20 - Privacy can’t be an afterthought for a protocol15:24 - Encrypted

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58:47

Samo Burja: Building an Immortal Society

Arjun Khemani Podcast ·

2025/07/11

My conversation with Samo Burja, founder of Bismarck Analysis. He chairs the editorial board of Palladium Magazine.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:00 - Intro1:18 - Live players5:41 - Great Founder Theory11:20 - Our material technology rests on our social interactions14:23 - Optimism, pessimism, and

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94:11

Zooko Wilcox and Josh Swihart: Unstoppable Private Money

Arjun Khemani Podcast ·

2025/06/03

My conversation with Zooko Wilcox and Josh Swihart on unstoppable private money.Zooko Wilcox is a legendary cypherpunk and one of the founders of Zcash—private, digital money.Josh Swihart is the CEO of Electric Coin Company, the team behind the Zcash protocol and the Zashi wallet app.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:00 - Maya

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52:37

Ethan Thornton: The Future of Warfare

Arjun Khemani Podcast ·

2025/03/15

My conversation with Ethan Thornton, founder of Mach Industries.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:00 - Intro1:07 - Why Mach needs to exist3:16 - Early experiments5:07 - Dropping out of MIT8:36 - Raising $85 million at 19 years old11:20 - Decentralized vertical supply chains13:54 - The most important

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75:57

Peter Boghossian: Moral Relativism and The Future of...

Arjun Khemani Podcast ·

2025/02/26

My conversation with philosopher and author Peter Boghossian.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:00 - The enlightenment5:51 - The dangers of moral relativism21:28 - Modern education is failing us31:14 - What’s worth preserving in the West37:00 - Is wokeism filling the void left by atheism?38:04 - The

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200:38

Zooko, Nate Wilcox, and Sean Bowe: Zcash

Arjun Khemani Podcast ·

2025/01/22

My conversation with Zooko, Nate Wilcox, and Sean Bowe about the Zcash protocol.Zooko is a cypherpunk who co-founded Zcash along with his brother, Nate Wilcox, and others. Sean Bowe is a cryptographer and engineer who has played a crucial role in the development of Zcash and has made significant contributions to advancements in zero-knowledge proofs, particularly zk-SNARKs, which underpin Zcash’s privacy features.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X

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73:45

Naval Ravikant: The Beginning of Infinity

Arjun Khemani Podcast ·

2024/12/18

My conversation with Naval Ravikant. Enjoy!Watch on YouTube or X. Listen on Apple Podcasts or Spotify.Click here to support my work.Timestamps0:00 - The Theory of Everything4:48 - How do you know what’s true?7:51 - Groups search for consensus, individuals search for truth13:07 - We have never run out of a single resource15:25 - Are we destroying the Earth?17:48 - Marxism denies wealth creation21:28 - Regulation kills innovation27:05 - Degrowth and the fall of Western universities33:31 - Why the West

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89:06

David Deutsch: The Era of Man, Popper, and Western...

Arjun Khemani Podcast ·

2024/11/11

I had the pleasure of sitting down with David Deutsch in his lovely garden in Oxford a few months ago. Here’s our conversation.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps1:01 - A tragic view of human history7:04 - Why did it take so long for civilization to arise?13:31 - Fallibilism21:32 - Cultural relativism

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115:00

#35 – Julian Barbour and Samuel Kuypers: The Nature...

Arjun Khemani Podcast ·

2024/09/15

Julian Barbour is a renowned physicist known for his groundbreaking work on the nature of time. In his influential books, The End of Time and The Janus Point he explores the concept of a timeless universe, challenging traditional views. Samuel Kuypers is a theoretical physicist, currently located in Montréal, who is interested in the foundations of quantum theory and time.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any

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63:29

#34 – Nat Eliason: Crypto Confidential, Writing, and...

Arjun Khemani Podcast ·

2024/07/26

Click here to support my work. You can also send me bitcoin to this address.Nat Eliason is a writer and crypto insider with a wildly popular newsletter and podcast. He is the author of the book Crypto Confidential: Winning and Losing Millions in the New Frontier of Finance.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Timestamps0:49 - Ayn Rand6:40 - The

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53:04

#33 – Johan Norberg: Capitalism, Degrowth, and Elon Musk

Arjun Khemani Podcast ·

2024/07/16

Johan Norberg is a senior fellow at the Cato Institute and a writer who focuses on globalization, human progress and intellectual history. He is the author of In Defense of Global Capitalism, Progress: Ten Reasons to Look Forward to the Future, and The Capitalist Manifesto: Why the Global Free Market Will Save the World.Topics we discuss are well captured by the timestamps below. I hope you enjoy this episode as much as I enjoyed recording it!Watch on YouTube or X. Listen on Apple Podcasts, Spotify,

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76:44

#32 – Riva Tez: Anarchy, Beauty, and Longevity

Arjun Khemani Podcast ·

2024/07/04

Riva Tez is a philosopher, writer, and venture capitalist. She’s the author of the blog Hard to Write.Topics we discuss are well captured by the timestamps below. I hope you enjoy this episode as much as I enjoyed recording it!Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:52 - Does crypto make anarcho-capitalism pragmatic?11:56 - Crypto is both technologically and

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36:38

#31 – Nicole Behnam: Leveraging Social Media,...

Arjun Khemani Podcast ·

2024/06/25

Nicole Behnam is a founder and journalist. She is the creator of Beyond The Interview where she’s interviewed people like Chris Voss, Konstantin Kisin, and Robert Greene.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:00 - Nicole’s relationship with her parents and books4:45 - On being a red carpet host9:57 -

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57:20

#30 – Niklas Anzinger: Longevity, Crypto, and Network...

Arjun Khemani Podcast ·

2024/06/05

Niklas Anzinger is the founder of Infinita VC and Vitalia. He is also the host of the Podcast.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:32 - Building Vitalia and Infinita VC6:05 - The parallels between longevity and crypto17:35 - How to convince people that living longer is a worthy goal22:54 - Network

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42:21

#29 – Ashley St. Clair: Immigration Crisis, Free...

Arjun Khemani Podcast ·

2024/05/14

Ashley St. Clair is the Operations Manager at Babylon Bee and author of the children’s book Elephants Are Not Birds. This interview was recorded on Airchat.Topics we discuss are well captured by the timestamps below.Watch on YouTube or X. Listen on Apple Podcasts, Spotify, or any other podcast platform. Follow me on X for updates on future episodes.Click here to support my work.Timestamps0:19 - The immigration crisis in the US11:08 - DEI and Mark Cuban14:29 - Anti-humanism and Gen Z18:17 - The rise

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