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PODCAST

The Orange Pill Podcast

The Orange Pill Podcast 🎙️ Your go-to source for the latest in the dietary supplement and natural health product industry! Brought to you by KGK Science, a global leader in clinical research and regulatory consulting, this podcast delivers: ✔️ Breaking industry news and trends ✔️ Educational insights and practical takeaways ✔️ Discussions on cutting-edge research ✔️ Landmark cases and notable events shaping the field Join us as we bridge the gap between science, regulation, and everyday impact.

health & fitness nutrition

All Episodes

33:27

Episode 79- Why You Can’t See Government-Backed...

The Orange Pill Podcast ·

2026/01/09

When you scan a food or supplement label, you might assume you’re seeing the most credible health information available. But what if some of the most authoritative, government-backed science is being kept off labels altogether?In this episode of the Orange Pill Podcast, we unpack a new legal battle that’s putting the FDA’s regulatory authority, free speech, and consumer rights under the spotlight. At the center of the case is a surprising contradiction: claims drawn directly from research published

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37:44

Episode 78- From Tossing and Turning to Real Rest:...

The Orange Pill Podcast ·

2026/01/06

More than one in four adults struggle to fall or stay asleep and while prescription sleep aids can help, they often come with side effects like grogginess, confusion, and memory impairment. That’s why researchers are increasingly searching for safer, evidence-based alternatives. In this episode of the Orange Pill Podcast, we dive into a fascinating new triple-blind, placebo-controlled clinical trial published in Food Science & Nutrition that explored a standardized Corn Leaf Extract (CLE) as a

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37:22

Episode 77- Inflammation, Cheese, and Personal...

The Orange Pill Podcast ·

2025/12/18

As dementia rates climb worldwide, projected to reach nearly 153 million cases by 2050, diet has emerged as one of the most important modifiable risk factors. But the science behind “brain food” is far more complex than simply avoiding certain foods or adding others.In this final episode of the year, the Orange Pill Podcast takes a deep dive into three surprising scientific findings that are reshaping how we think about diet and long-term cognitive health. In Episode 77, we explore: • Why the

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35:08

Episode 76- Supplements on the Front Line: What the...

The Orange Pill Podcast ·

2025/12/16

Dietary supplements promise strength, focus, resilience, and disease prevention, but how well do we truly understand their benefits and risks?In Episode 76 of the Orange Pill Podcast, we take a deep dive into one of the most comprehensive investigations of supplement use ever conducted: a Department of Defense–commissioned report by the Institute of Medicine examining dietary supplement use among U.S. military personnel- one of the world’s most physically and mentally stressed populations. This

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28:54

Episode 75- This Gut Bacteria Byproduct Melts Fat...

The Orange Pill Podcast ·

2025/12/11

Weight-loss science is having a renaissance. While today’s blockbuster drugs curb appetite by acting on the brain, a groundbreaking new discovery points to an entirely different frontier - one inside the gut. In Episode 75 of the Orange Pill Podcast, we explore a remarkable molecule produced not by our bodies, but by our gut bacteria. It’s called Desaminotyrosine (DAT), and new research suggests it could help the body burn fat faster, cleaner, and without ever decreasing appetite. This discovery

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25:36

Episode 74- Beyond Calm: 4 Surprising Scientific...

The Orange Pill Podcast ·

2025/12/09

In a world where stress is constant and focus feels fleeting, many people turn to L-theanine, the calming amino acid found in green tea. But new clinical research on a purified form, AlphaWave® L-Theanine, reveals a story far more sophisticated than the usual “relaxation without drowsiness” claim. In Episode 74 of the Orange Pill Podcast, we unpack four surprising scientific discoveries that challenge long-held assumptions about L-theanine and how it affects the brain: 1️⃣ It creates a measurable

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26:29

Episode 73- A Gene-Edited Fungus That Eats Less,...

The Orange Pill Podcast ·

2025/12/02

The global protein crisis is here and science may have just delivered an unexpected solution: a gene-edited fungus that uses 44% less sugar, grows 88% faster, produces clean, complete protein, and still tastes remarkably like meat.In this episode of the Orange Pill Podcast, we dive into groundbreaking new research on Fusarium venenatum, the same fungus behind mycoprotein, and explore how a precise, “scarless” CRISPR edit is reshaping the sustainability, nutrition, and future potential of

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43:17

Episode 72- Beyond the Hype: 5 Surprising Truths...

The Orange Pill Podcast ·

2025/11/20

The supplement aisle is packed with promises - better sleep, stronger immunity, improved focus - but how much of it is truly backed by science?In this episode of the Orange Pill Podcast, we go beyond the marketing noise to explore five surprising truths decades of research have revealed about dietary supplements. From the downfall of once-hyped herbal remedies to the rise of personalized nutrition and the untapped influence of the gut microbiome, this episode challenges the outdated “one nutrient,

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35:05

Episode 71- 4 Surprising Reasons the “Better FDA Act”...

The Orange Pill Podcast ·

2025/11/18

Most of us trust that the foods we buy are safe and clearly labeled, but a new bill in Washington may quietly change the rules.In this episode, we break down the “Better Food Disclosure Act of 2025”, a bill introduced by Senator Roger Marshall that promises to strengthen transparency in the food system. At first glance, it looks like progress. But beneath the surface are four major structural issues that critics warn could actually weaken food safety regulation, not strengthen it. We explore: •

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36:28

Episode 70- 5 Surprising Truths About Health Products...

The Orange Pill Podcast ·

2025/11/13

That “Clinically Proven” label on your favorite supplement might not mean what you think. In this episode, we peel back the curtain on the world of health product research, where not all studies are created equal.Join us as we explore five surprising truths about how health products are tested, from the misuse of patient-reported outcomes (PROs) to the hidden pitfalls of fully virtual trials. You’ll learn why the FDA is cracking down on vague “quality of life” claims, how some trials rely on

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28:45

Episode 69- 3 Surprising Legal Trends Every U.S....

The Orange Pill Podcast ·

2025/11/11

The U.S. dietary supplement industry is thriving, but beneath the surface of growth lies a rising wave of class action litigation that’s reshaping how brands think about packaging, marketing, and labeling. In this episode of the Orange Pill Podcast, we uncover three emerging legal trends every supplement company should know: 1️⃣ Slack-fill lawsuits - why “empty space” in your packaging could cost millions. 2️⃣ Protein spiking claims - the controversy shaking up the protein powder market. 3️⃣ “Made

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36:38

Episode 68- From Substance to State: How the...

The Orange Pill Podcast ·

2025/11/06

The legalization of cannabis has created a billion-dollar problem that technology is only now catching up to solve: how can we accurately measure impairment, not just use?In this episode of the Orange Pill Podcast, we dive into groundbreaking research featuring the Cognalyzer®- a novel EEG-based device that measures brainwave alterations to detect cannabis impairment directly. Unlike traditional methods such as saliva or blood tests, which can penalize sober individuals long after consumption, this

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46:52

Episode 67- A Major New Study Reveals a Surprising...

The Orange Pill Podcast ·

2025/11/04

Aggression, from playground fights to serious violence, has long challenged families and communities alike. But what if one of the simplest, safest, and most effective tools for reducing aggression has been sitting on our dinner plates all along? In this episode, we explore a groundbreaking new meta-analysis spanning nearly 30 years of research that reveals how omega-3 supplementation, the same fatty acids found in fish oil, can reduce aggression by up to 30%. Join us as we unpack: The evidence

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42:40

Episode 66: The Super-Nutrients in Your Food Aren’t...

The Orange Pill Podcast ·

2025/10/23

We all try to eat better, loading up on antioxidant-rich berries, turmeric, and green veggies, but here’s the surprising truth: many of those “super-nutrients” never make it past your digestive system.In this episode of the Orange Pill Podcast, we explore how nanotechnology is rewriting the rules of nutrition. From nanoencapsulation that protects fragile compounds like curcumin and quercetin, to upcycling food waste into potent new supplements, science is finally addressing the “bioavailability

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39:50

Episode 65- The Hidden Dangers of Biogenic Amines:...

The Orange Pill Podcast ·

2025/10/21

Fermented foods like cheese, wine, and cured meats are celebrated for their complex flavors, but they may harbor hidden risks. In this episode of The Orange Pill Podcast, we explore the world of biogenic amines (BAs), naturally occurring compounds that can pose health hazards despite their delicious origins. From the “cheese effect” of tyramine to toxic synergy among multiple amines, we discuss why regulating histamine alone isn’t enough. Learn why food safety experts are calling for clear

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29:02

Canada’s CBD Crossroads: Health Canada’s Next Big...

The Orange Pill Podcast ·

2025/10/16

In Episode 64, we continue to unpack the regulatory evolution of cannabis and cannabidiol (CBD) in Canada (continuation of Episode 44) and what’s next for the industry. From the Cannabis Act to proposed pathways that could finally allow CBD Natural Health Products (NHPs) to be sold without prescriptions, this episode dives deep into how Health Canada’s changing stance could reshape accessibility, innovation, and economic opportunity.

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24:34

Episode 63- Government Shutdown 2025: From Furloughs...

The Orange Pill Podcast ·

2025/10/14

For most Americans, a government shutdown means furloughs, temporary disruptions that end when funding returns. But October 2025 marks a turning point. The Trump administration’s move to issue Reductions in Force (RIFs) across key agencies like HHS, FDA, and the CDC has transformed a short-term budget standoff into a permanent restructuring of the federal workforce.In this episode, we break down: The difference between a furlough and a RIF, and why it matters now more than ever. The scale of

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23:32

Episode 62- NMN is Back: Inside the FDA’s Reversal...

The Orange Pill Podcast ·

2025/10/07

After nearly three years of uncertainty, the FDA has officially reversed its stance on Nicotinamide Mononucleotide (NMN), the popular anti-aging compound once banned from supplement shelves.In this episode, we unpack the twists and turns that led to the agency’s dramatic U-turn, the key legal reinterpretation that changed everything, and how relentless industry advocacy forced the FDA’s hand. From Citizen Petitions to regulatory chaos, discover what really happened behind the scenes, and why this

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40:34

Episode 61-More Than Weight Loss: How the Bone Broth...

The Orange Pill Podcast ·

2025/10/02

Most diets promise weight loss but leave you battling hunger, losing precious muscle, and facing rebound weight gain. But what if there’s another way?In this episode of the Orange Pill Podcast, we break down a recent clinical trial published in Clinical Nutrition Open Science that tested the Bone Broth Diet (BBD), a mix of intermittent fasting, high-protein/low-carb meals, and collagen-rich bone broth. The results? Surprisingly powerful: ✅ Fat loss with muscle preservation ✅ Reduced hunger and

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40:52

Episode 60- The Fermentation Revolution: 5 Ways an...

The Orange Pill Podcast ·

2025/09/30

From sourdough bread to kombucha, fermentation has long been a cornerstone of human diets. But what was once a preservation method is now driving some of the boldest innovations in food science. In this episode, we explore five surprising ways fermentation is transforming the future of food—from unlocking hidden nutrition and reintroducing microbial diversity, to turning food waste into gourmet ingredients, breeding microbes for flavor, and even creating animal products without the

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79 results

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