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PODCAST

To Health With That! MTHFR Mutations and Methylation.

This podcast breaks up BIG health topics, like MTHFR and methylation, into small, easy bites. All in ten minutes or less. We"ll discuss why folic acid can be toxic, how the MTHFR enzyme links to estrogen and toxins, why you want to turn genes off, and how folate and mental health are connected. 2024-2025 will add new "bonus" episodes to Season 1 to clarify and revise concepts while Dr. Amy is writing a book. Check linked blogs at tohealthwiththat.com for more info and downloadable. Join us in

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All Episodes

00:14:27

Kelsey's MTHFR Story - Hormones, blood sugar and...

To Health With That! MTHFR Mutations and Methylation. ·

2025/12/21

Today, Kelsey is kind enough to share her and her family's journey with MTHFR. Like the rest of us, their journey has unfolded slowly with a lot of personal research along the way.00:00 - Intro00:38 - Meeting Kelsey01:11 - How she found out about MTHFR02:18 - Quest to learn about MTHFR03:23 - High dose folic acid in pregnancy and pregnancy complications04:09 - The MTHFR highlights - ADHD, difficult fertility, weird pregnancy symptoms, sensitivities.04:39 - Eliminating folic acid, starting gummy

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00:12:20

Betsy's MTHFR Story - Rheumatoid Arthritis,...

To Health With That! MTHFR Mutations and Methylation. ·

2025/12/07

Season 5, Episode 7 of the To Health With That! podcast. Betsy and I recorded this video several years ago (hence the hair!) and she was kind enough to consent to share it in this format as well. Betsy's history as a nurse gives her a wonderful, insightful perspective on healthcare and her journey with autoimmune disease and having to take an antifolate will help so many other individuals who are struggling with this issue.00:00 - Intro00:36 - Betsy’s Story with Autoimmune disease03:20 -

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00:13:49

Kristyn's MTHFR Story - Fatigue, Anxiety, Pericarditis

To Health With That! MTHFR Mutations and Methylation. ·

2025/11/23

Thank you so much to Kristyn for sharing her MTHFR story with us. Kristyn has only known she had an MTHFR gene variant for three months, but it makes sense of many of the symptoms she has had her whole life like fatigue, difficulty sleeping, and anxiety. MTHFR could be contributing to her recurrent pericarditis and kidney disease.Kristyn shares her journey with diet and supplements and trying to balance more energy with more sleep.This story is generously shared with permission to post to

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00:15:56

Tony's MTHFR Story Part 2 - Tumors, surgery, and...

To Health With That! MTHFR Mutations and Methylation. ·

2025/11/09

To Health With That! Podcast Season 5, Episode 5. Thank you so much to Tony for generously sharing his story - the full interview was fabulous and included much more than we could put in one podcast episode, so we broke it into two. In this episode, Tony continues to share with the idea of MTHFR being a rebirth, new information he has about a tumor and his concerns about folate and tumor growth, and questions about MTHFR and anesthesia.00:00 - Introduction00:43 - Manageable steps01:07 - Symptom

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00:15:39

Tony's MTHFR Story - Part I. Anxiety, overwhelm,...

To Health With That! MTHFR Mutations and Methylation. ·

2025/10/26

To Health With That! Podcast Season 5, Episode 4. Thank you so much to Tony for generously sharing his story - the full interview was fabulous and included much more than we could put in one podcast episode, so we broke it into two. In this episode, Tony shares his frustration at feeling bad, but doctors telling him he's "normal", the relief at finding MTHFR, which makes his symptoms make more sense, and the beginnings of his journey so far. He talks about brain fog, fears of cognitive

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00:14:01

Karene's MTHFR Story - ADHD, Sensitivity and Nutrient...

To Health With That! MTHFR Mutations and Methylation. ·

2025/10/12

Thank you so much to Karene for generously sharing her story! Karene is new to MTHFR - she just found out that she and her children have an MTHFR gene mutation one week ago. Karene tested because of ADHD for herself and one of her sons, and is just starting to learn about the gene SNP and what to do. 00:30 - Introducing Karene01:03 - ADHD diagnosis01:39 - Why MTHFR explains so much for her son02:14 - MTHFR and ADHD02:47 - Methyl folate start02:14 - Trying to make sense of all the information04:01 -

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00:14:06

Mary's MTHFR story - MTHFR and repeat pregnancy loss.

To Health With That! MTHFR Mutations and Methylation. ·

2025/09/28

MTHFR Stories are interviews with regular people who have MTHFR and are willing to share their health journey to help others. Mary's MTHFR journey centers around pregnancy loss with several second-trimester miscarriages and a stillbirth. She bravely talks about the exhaustion that she has struggled with after such a deep physical toll was taken on her body by the pregnancies, and the emotional journey she has been on. Mary has other issues associated with MTHFR as well including hypermobility

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00:12:33

Lisa's MTHFR story - perfection, MTHFR, and...

To Health With That! MTHFR Mutations and Methylation. ·

2025/09/07

Lisa's story is a testament to what having a community of people can do for your health journey. Lisa touches on many familiar MTHFR issues - allergies, impatience, food sensitivities, blood sugar imbalance, struggles with weight, lip tie, and perfectionism. Her biggest hurdles on this journey have been about self-acceptance and also learning to have patience and not over-push her body. She is sharing those lessons with her children and grandchildren in a way that is so inspiring for all of us

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00:03:41

What is Happening In Season Five? YOU'RE COMING ON...

To Health With That! MTHFR Mutations and Methylation. ·

2025/07/20

The To Health With That! Podcast for MTHFR folks has been a wild ride, but so far it's really just Dr. Amy talking about MTHFR.In Season Five, which will start airing in September, I want YOU to talk. Tell me about your experience of being a person with MTHFR gene mutations, tell me what has helped you, what hasn't been helpful, and what you want all the other MTHFR folks out there to know.Your journey probably has other conditions intersecting as well. Maybe it's diabetes, migraines,

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00:09:39

Methylation Adaptogens, or Proof that God Loves Us.

To Health With That! MTHFR Mutations and Methylation. ·

2025/06/01

In the last episode, we talked about CBD as a methylation adaptogen, but we haven' talked too much about that term so let's dive in. We know that everyday methylation is important for people with the MTHFR gene or with any methylation dysfunction, but it turns out that long-term methylation care is important too and this can be achieved by getting methylation adaptogens.Methylation adaptogens are substances that help to regulate the amount your genes are methylated. Remember that when genes are

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00:09:42

MTHFR and Marijuana. - What We Know Now.

To Health With That! MTHFR Mutations and Methylation. ·

2025/04/27

Pot is the third most used drug in North America after alcohol and tobacco, so questions about Cannabis and MTHFR are important to ask. The answers, of course, are mixed with some serious pitfalls and also some surprising benefits of CBD for people with MTHFR gene mutations.Nothing is ever fully good or fully bad, and marijuana for MTHFR is the same. When you have an MTHFR gene variant, it is important to know your own risks to make an educated decision about what you want to put in your body

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00:09:51

The Artist and The Activist Methylation Personality...

To Health With That! MTHFR Mutations and Methylation. ·

2025/03/16

Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, show themselves in four distinct personality types. These methylation personality types, methylation archetypes, or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Activist and The Artist are very closely linked. Neither are terribly ambitious or driven, except in the thing that matters to them, whether it's their art, their job (which might

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00:08:08

The Achiever and The Athlete Personality Types

To Health With That! MTHFR Mutations and Methylation. ·

2025/02/23

,Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, shows itself in four distinct personality types. These methylation personality types, methylation archetypes or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Achiever and The Athlete are very closely linked. Both are extremely ambitious, perfectionistic, competitive, and driven. Both tend to have more allergic-type reactions to the world

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00:09:01

Discover Your Methylation Personality: Achiever,...

To Health With That! MTHFR Mutations and Methylation. ·

2025/01/12

Methylation imbalance, often caused by the MTHFR gene mutation, by folic acid excess, or by nutritional deficiencies, shows itself in several personality traits. Some personality traits are common to people with methylation dysfunction, like perfectionism, OCD-tendencies, anxiety, hyper-focus or hypo-focus, and others. These common traits emerge in each methylation archetype pattern in slightly different ways, and by using your personality to determine your methylation archetype, you can benefit

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00:07:54

Are Overmethylator and Undermethylator Still Useful...

To Health With That! MTHFR Mutations and Methylation. ·

2024/12/22

I have used the terms over methylator and undermethylation in the past to help categorize people to streamline their supplement start with MTHFR or other methylation imbalance, but the terms themselves can be confusing and misleading because they imply a biochemical state that isn't actually there. Logically, it makes sense that an undermethylator would be globally undermethylating things, but that doesn't bear out in reality, and part of that is because these terms (over- and under-methylator)

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00:06:40

How Much Methyl Folate is Too Much for MTHFR?

To Health With That! MTHFR Mutations and Methylation. ·

2024/11/17

She breaks down the considerations for symptom management and potential risks, particularly regarding tumors and blood labs. In this episode of 'To Health With That,' naturopathic doctor Amy Neuzil discusses the complexities surrounding methylfolate dosing for individuals with MTHFR. High doses of methylfolate could come with some of the same risks as high-dose folic acid, so it's essential to find the right dose for you without overdoing it. The three factors to consider are symptom management,

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00:09:03

The Risks of High Dose Folate

To Health With That! MTHFR Mutations and Methylation. ·

2024/10/20

Folate is a great thing - it's vitamin B9 and your body needs it to make new cells, replicate DNA, and so much more. But there are risks of too much folate, so how much folic acid is too much? And how dangerous is it to take high dose folic acid over time? The research exists for high dose folic acid, but what about L-5MTHF, or methyl folate? Does high dose methyl folate have the same risks as high dose folic acid?We have so many questions, and very few definitive answers, but there is lots of

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00:02:55

What's Happening With The THWT Podcast in September?

To Health With That! MTHFR Mutations and Methylation. ·

2024/07/14

That's right - season 4 of the To Health With That podcast is finished, so let's talk about what you should be doing this summer (having fun), what I should be doing in the fall (writing), and what kind of episodes you can expect. I'd like to call it To Health With That! Season One BONUS Episodes. Thanks so much for being here and adding so much in terms of comments and questions - I couldn't do this without you. In September we'll have occasional episodes about methylation

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00:10:49

Gentle Six Week Detox For MTHFR

To Health With That! MTHFR Mutations and Methylation. ·

2024/06/30

Gentle MTHFR Detox ProtocolA gentle six-week detoxification protocol tailored for individuals with MTHFR polymorphism. She explains how decreased methylation in MTHFR polymorphism sufferers leads to toxin accumulation and stresses the importance of detoxification. The protocol includes preparatory steps, recommended supplements like NAC and liposomal glutathione, dietary adjustments, and lifestyle changes aimed at supporting the body's detox process. Additionally, she discusses the health

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00:06:07

Heal Your Adrenals - Part Two

To Health With That! MTHFR Mutations and Methylation. ·

2024/06/16

In Season 4, Episode 21 of the To Health With That podcast, naturopathic doctor Amy Neuzil discusses strategies to combat fatigue by focusing on adrenal health. The episode covers the concept of adrenal fatigue, identifying it in various phases, and introduces a holistic approach to healing the adrenals, emphasizing the role of supplements such as Vitamin C, Magnesium, B Vitamins, and melatonin, along with a special focus on adaptogens like Siberian ginseng, ashwagandha, and holy basil. Neuzil

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