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PODCAST

Unexplainable

Unexplainable takes listeners right up to the edge of what we know…and then keeps on going. The Unexplainable team — Noam Hassenfeld, Julia Longoria, Byrd Pinkerton, and Meradith Hoddinott — tackles scientific mysteries, unanswered questions, and everything we learn diving into the unknown. New episodes Mondays and Wednesdays. From Vox and the Vox Media Podcast Network.

science life sciences

All Episodes

29:02

The accidental rise of Botox

Unexplainable ·

2026/03/18

One of the deadliest poisons known to man is now used to treat wrinkles, migraines, and even, maybe, depression. How did that happen?Guests: Jean Carruthers, ophthalmologist and “godmother” of cosmetic Botox. David Simpson, neurologist at Mount Sinai hospital in New York. Axel Wollmer, psychiatrist at the Asklepios clinic in Hamburg, Germany. For more, go to http://vox.com/unexplainable It’s a great place to sign up for our newsletter, view show transcripts, and read more about the topics on

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31:41

Who are we to fight the alchemy?

Unexplainable ·

2026/03/16

Many alchemical texts are full of bizarre, metaphorical language. But what if there's interesting science hiding behind some of those metaphors?Guest: Lawrence Principe, professor of the history of science and professor of chemistry at Johns Hopkins University For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us! ⁠⁠⁠unexplainable@vox.com⁠⁠⁠ We read every email. Support

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28:31

Snow day!

Unexplainable ·

2026/03/11

Grab some hot cocoa and a warm blanket and let’s talk about the tiny crystals that fall from the sky.Guest: Jessica Lundquist, professor of civil & environmental engineering at the University of Washington For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us! ⁠⁠⁠unexplainable@vox.com⁠⁠⁠ We read every email. Support Unexplainable (and get ad-free episodes) by becoming a Vox

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27:20

My brain made me do it

Unexplainable ·

2026/03/09

A man committed a crime. He admitted it. Then something alarming showed up on an image of his brain. The criminal case that followed in 1991 brought neuroscience into the courtroom for good. How does our ever-changing understanding of the brain impact how we approach justice? Guests: Josh May, professor of philosophy, University of Alabama, Birmingham, author of Neuroethics: Agency in the Age of Brain Science, Anthony Wagner, neuroscientist and professor of psychology, Stanford University Memory

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39:21

The Codfather

Unexplainable ·

2026/02/25

How many fish are in the sea? It's a question that has had enormous consequences for the fishing community in New Bedford, Massachusetts. But one man managed to find a way around it. That man? The Codfather.Guest: Ian Coss, host and producer of WBGH's Catching the Codfather For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us

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14:58

Stress ages us on a cellular level

Unexplainable ·

2026/02/23

It's no secret that stress isn't good for you… But just how bad is it? NPR's Short Wave podcast gets some answers. Host: Regina G. Barber, host of NPR’s Short Wave podcast Guest: Diana Kwon, science journalist Follow NPR's Short Wave podcast on Apple Podcasts and Spotify for more episodes like this, featuring new discoveries, everyday mysteries and the science behind the headlines. Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+

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26:26

The Amazing Extremophiles

Unexplainable ·

2026/02/11

In the dark depths of the Gowanus Canal, strange lifeforms lurk...Guests: Brad Vogel, volunteer at the Gowanus Dredgers Canoe Club; Elizabeth Hénaff, computational biologist and artist at New York University For more, go to http://vox.com/unexplainable It’s a great place to sign up for our newsletter, view show transcripts, and read more about the topics on our show. Also, email us! unexplainable@vox.com We read every email. Support Unexplainable by making a financial contribution to Vox

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39:35

Everyone does it. Why can’t I?

Unexplainable ·

2026/02/09

I’m about to burst.Guests: Laryngologist Dr. Robert Bastian and Noel King, co-host and editorial director of the Vox daily news podcast Today, Explained For more, go to http://vox.com/unexplainable It’s a great place to sign up for our newsletter, view show transcripts, and read more about the topics on our show. Also, email us! unexplainable@vox.com We read every email. Support Unexplainable by making a financial contribution to Vox! bit.ly/givepodcasts Learn more about your ad choices

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26:16

Mysterious objects near the beginning of time

Unexplainable ·

2026/02/04

Astronomers are putting together a new picture of the early universe. It involves a lot of very weird black holes, and it could help us understand how our own galaxy formed.Guest: Caitlin Casey, astronomer at UC Santa Barbara ⁠ For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us! ⁠⁠⁠⁠⁠⁠unexplainable@vox.com⁠⁠⁠⁠⁠⁠ We read every email. Support

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29:02

Cloud atlas

Unexplainable ·

2026/02/02

It’s surprisingly hard to predict how clouds form, move, and change, but it’s essential to try. Because how clouds react to a warming world helps determine how hot our future will be.Guests: Vox contributor Umair Irfan, scientists Scott M. Collis, Angeline Pendergrass, and author Gavin Pretor-Pinney For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more, go to

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26:29

What's good sound?

Unexplainable ·

2026/01/28

Every hand-crafted instrument from violin maker Michael Doran holds its own unexplainable questions. Guest: Michael Doran of Doran’s Violin’s For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us! ⁠⁠⁠⁠⁠⁠unexplainable@vox.com⁠⁠⁠⁠⁠⁠ We read every email. Support Unexplainable (and get ad-free episodes) by becoming a Vox Member today:

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23:26

No data, just vibes

Unexplainable ·

2026/01/26

There's been a real rollback of one of the US government's most fundamental tasks: gathering data. Vox correspondents Dylan Scott and Umair Irfan take a look at what a future with less data means for climate and health care in the US. Guests: Vox correspondent Umair Irfan and Vox senior correspondent Dylan Scott For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email

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25:23

It's not all bad

Unexplainable ·

2026/01/14

Things in the news have been feeling kind of…bleak, so we called in some reinforcements. Vox's senior editorial director and resident good news expert Bryan Walsh joins editor Joanna Solotaroff to remind us that there’s still a lot of good stuff happening, too.Guest: Vox senior editorial director Bryan Walsh. Sign up for the Good News newsletter HERE. For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠For more, go to

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25:56

Superbabies?

Unexplainable ·

2026/01/12

Parents are supposed to provide the best life possible for their kids, right? But what does that mean when genetic testing for the baby enters the picture? And how far should they go? Vox senior reporter Sigal Samuel received that ethically ambiguous question for her advice column Your Mileage May Vary from a parent-to-be, and in this episode walks Noam through her thinking using a philosophical framework. For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For

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26:47

The G-word

Unexplainable ·

2026/01/07

Is geoengineering the answer to the climate crisis? Or is it too dangerous to even discuss? It’s been theoretical so far, but now, one startup says their technology could soon shield the Earth from the sun.Guest: Robinson Meyer, climate journalist and founding executive editor of Heatmap News. For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us

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23:02

Who's afraid of big, bad Yellowstone?

Unexplainable ·

2026/01/05

Yellowstone can be a deadly place... but not for the reasons you might think. Guest: Mike Poland, scientist in charge at the Yellowstone Volcano Observatory For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ And please email us! ⁠⁠⁠⁠unexplainable@vox.com⁠⁠⁠⁠. We read every email Support Unexplainable (and get ad-free episodes) by becoming a Vox Member today:

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32:26

Vitamin C and the common cold

Unexplainable ·

2025/12/17

A two-time Nobel Prize-winning scientist changed chemistry, biology, and the politics of science. But when he pushed vitamin C as a cure-all, did he go too far? Guest: Daniel M. Davis, head of the department of life sciences and professor of immunology at Imperial College London. He is the author of Self-Defense: A Myth-Busting Guide to Immune Health. For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to

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31:42

Your moments of silence (The Sound Barrier #5)

Unexplainable ·

2025/12/15

This episode is a follow-up to The Sound Barrier series, which explores our brain's relationship to sound. In our third episode of the series, we asked listeners to try to experience silence and record what they heard. Today, we share the sounds of quiet from across the world in a tribute to John Cage’s 4’33”. Plus, Tinnitus researcher and Unexplainable guest Dan Polley answers your questions from the series. Guest: Dan Polley, tinnitus researcher at Mass Eye and Ear. Thank you to everyone who

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27:13

Diary of a teenage brain, part 2

Unexplainable ·

2025/12/10

As our brains develop throughout our childhood and teens, they form connections and then prune back the ones that aren't used. What can we learn from them?Guests: Alison Barth, professor in the life sciences at Carnegie Mellon University; Saket Navlakha, associate professor at Cold Spring Harbor Laboratory This series was made possible by support from the Annie E. Casey Foundation. Vox had full discretion over the content of this reporting. For show transcripts, go to

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28:38

Diary of a teenage brain

Unexplainable ·

2025/12/08

What's going on in teens' heads? Scientists working on a country-wide study following thousands of young people have spent the last decade trying to answer that question. Guests: Raul Gonzalez Jr., psychology professor at Florida International University This series was made possible by support from the Annie E. Casey Foundation. Vox had full discretion over the content of this reporting. For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to

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