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PODCAST

Biohacking Beauty: The Anti-Aging Skincare Podcast

Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond "single-molecule" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic

health & fitness alternative health

All Episodes

01:17:55

Dr. Alan Bauman: Why Biohackers Are Losing Their Hair...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/04/15

A lot of us treat hair loss the way skincare treats wrinkles, as a cosmetic problem to cover up. But almost every case of thinning, recession, or shedding has something deeper driving it, and by the time it shows up in the mirror, a significant amount of density is already gone.We at Young Goose believe that beauty is whole body care, and hair is one of the most metabolically active tissues in the body. It is also one of the first places systemic stress, hormone shifts, nutrient deficiencies, and

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32:20

The NAD+ Thief Your Skin Can't Escape: CD38, Zombie...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/04/08

Most people know NAD+ as a supplement trend. But very few understand what's actually happening inside their skin cells when it runs out or what's stealing it in the first place.By the time you're 45, you've lost half of the molecule that powers virtually every function keeping your skin young. Sadly, it only gets worse from there. The enzyme your skin uses for DNA repair can wipe out up to 90% of what's left after a single afternoon in the sun. This isn't a slow, graceful decline. It's a collapse

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57:37

Dani Conway: The Gut-Liver Detox Connection & How Gut...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/04/01

Most people treat their skin like a surface problem. But almost every persistent skin issue, from rosacea to eczema to accelerated aging, has something deeper driving it.That deeper driver is almost always the gut, the liver, or a backed-up detox pathway. We at Young Goose, always believe that skincare is whole body care and we want our community to identify the deeper causes of skin issues that products alone can’t fix.In this episode, functional nutrition practitioner Dani Conway joins us to break

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31:58

Skin Barrier Protocol: How One Reset Makes Every...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/03/25

Most people think that the stinging feeling, redness or tightness are always good signs of skin detoxification. Tricky enough, it can look like ‘glass skin’ or skin renewal. However, almost always the temporary tight and bright skin is a skin barrier issue in disguise.Skin barrier damage is one of the most misread signals in skincare. It looks like purging but it is actually your skin telling you it has been pushed past its limit.It’s easy to think there’s no damage at all because overexfoliation

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47:13

Sleep Is Skincare: How Timing Unlocks Your Body's...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/03/18

Did you know that the most powerful anti-aging protocol isn't about how long you sleep? It's about when. Getting eight hours of sleep for skincare feels like a tough feat to achieve especially when life gets in the way.By understanding how your skin begins its optimal repair time, it’s still possible to achieve the best skin results without the guilt of not sleeping enough.In our quest in finding the best skincare ingredient for our products, we discovered that hours of sleep do matter, but best

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58:47

Alex Tarnava: What Hydrogen Really Does to Your Skin

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/03/11

Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance, inflammatory regulation, and adaptive stress pathways. The key distinction is that delivery route changes mechanism. Oral, inhaled, and topical hydrogen act differently in the body, with different kinetics, tissue distribution, and biological implications.We dive deeper into this in the Biohacking

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01:12:53

Dr. Scott Sherr: Why Chronic Stress Disrupts...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/03/04

Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper symptoms appear.We dive deeper into this in the Biohacking Beauty Podcast with Dr. Scott Sherr. We also talk about the sympathetic spiral of doom, why skin reflects mitochondrial decline before other symptoms appear, and why sequencing interventions matter more than intensity.Dr. Scott Sherr is a

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01:24:17

Anastasia (Beauty Fascia): Facial Fascia and Massage...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/02/25

Fascia is one of the most overlooked conversations in skin aging. We spend so much time thinking about collagen, serums, injectables, and trending tools, but very few people are talking about the structural system underneath the skin that influences how we actually age.If you are dealing with under-eye puffiness, jaw tension, posture changes, facial asymmetry, or feeling like your face looks more tired than it should, this episode explores a deeper layer of the conversation. We dive into fascia,

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51:01

Dr. Jila Senemar, MD: How Early Perimenopause and...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/02/18

Being told your labs are “normal” and your cycle is still regular does not mean your metabolism and hormones are stable. Early insulin resistance can quietly increase inflammation, drive midsection fat gain, and accelerate skin aging years before menopause is officially diagnosed.In this Biohacking Beauty episode with Dr. Jila Senemar, we break down why regular periods do not rule out perimenopause, why building muscle is one of the most powerful metabolic tools in midlife, and how early testing

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58:47

Jess Kane (BodyBio): How Omega Ratios, Low Fat Diets,...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/02/11

Advanced skincare routines are more popular than ever, yet dryness, laxity, and visible aging still persist. The issue isn’t effort or discipline. It’s that skin aging is being treated as a surface-level problem instead of a cellular and structural one.We dive deeper into this in the latest Biohacking Beauty Podcast with Jess Kane. We also chat about how cell membrane health shapes visible aging, why omega fats are widely misunderstood, and how most “liposomal” supplements never reach the

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26:59

Valentine’s Day Special: Our Top Skincare...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/02/06

It’s Valentine’s Day, and while we don’t usually shape our work around holidays, this one felt different because we’re not just co-founders of Young Goose, we’re life partners. For us, care has always shown up in daily choices and consistency, the same philosophy behind how we think about skin longevity.In this special episode, we flip the format and recommend ingredients to each other based on real-time skin needs. We get into methylene blue, NAD support, ectoin, retinol, and repair-focused actives

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01:09:13

Marina Moiseyeva: Skin Detoxification, GLP-1s, and...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/02/04

Skin problems are often the body’s earliest warning sign that detoxification, inflammation control, and nutrient absorption are already compromised. When detox demand rises and recovery systems can’t keep up, skin changes and aging-related signs become more pronounced.In this episode of the Biohacking Beauty Podcast, we sit down with Marina Moiseyeva to explore why medications and aggressive topicals increase detox load, how sweating and lymphatic movement support skin longevity, and why “Ozempic

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01:09:43

Joe Radich (R3 Health): Why Skin Treatments Work...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/01/28

Advanced skin treatments often underperform for a reason rarely addressed: regeneration cannot occur in a chronically stressed or under-resourced system. Elevated cortisol, inflammation, and metabolic imbalance weaken collagen signaling and tissue repair before any device, injectable, or modality has a chance to work.In this episode of the Biohacking Beauty Podcast, we sit down with Joe Radich from R3 Health to unpack why physiological preparation determines treatment outcomes.We explore how

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53:14

Collagen vs. Elastin For Skin Aging: Why Collagen Is...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/01/21

Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping how skin functions long before changes fully register in the mirror.In this Biohacking Beauty episode, we unpack why rebuilding elastin is largely a myth, how elastin breakdown differs fundamentally from collagen loss, and how even a single period of stress can influence skin integrity for decades.We

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01:07:49

Dylan Gemelli: Injectable Peptides, PRP Exosomes and...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/01/14

Most conversations about advanced skin treatments stay at the surface, particularly around regenerative approaches, overlooking why lasting results are so hard to achieve.We dive deeper into this in the latest Biohacking Beauty episode with Dylan Gemelli. We explore why oral peptides often fall short, and how BPC-157 relates to gut healing, inflammation resolution, and collagen repair. We also unpack the real mechanism behind PRP facials, and how neuromodulating peptides compare to Botox over the

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01:08:13

How Winter Accelerates Skin Aging and the Best...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2026/01/07

Ever wonder why your skin changes so much in winter?In this episode of Biohacking Beauty, we explain what actually happens when humidity drops, TEWL rises and indoor heating pulls moisture from the skin. We also talk about UVA exposure in cold months, lifestyle shifts that increase oxidative stress and why winter puts more pressure on your skin’s repair systems.We break down the winter ingredients that matter most, like ceramides, barrier lipids, vitamin F, beta glucan, hyaluronic acid, peptides,

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58:05

Eva Hooft: How Emotions and Trauma Cause Aging Skin

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2025/12/31

What if fine lines, breakouts, and flare-ups are not just skin issues, but the body replaying old experiences it never got to resolve? In this episode, we explore how nervous system patterns, unresolved emotion, and the way we hold stress in the body can quietly shape how our skin ages over time. We look at the skin as a boundary, a canvas, and a reflection of how safe we feel in the world.We talk with practitioner Eva Hooft about psychosomatics, face mapping, and the cell danger response, and how a

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55:50

Liz Kennedy: Magnetic Beauty, Where Consciousness...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2025/12/24

Everyone is chasing the next skincare hack, yet true beauty begins far deeper than a product. It grows through awareness, alignment, and how we move through life.In this episode, we sit down with beauty expert and coach Liz Kennedy to explore how biohacking, mindset, and consciousness work together to create what she calls magnetic beauty. We discuss how affirmations, community, and daily rituals strengthen your energy, as well as how outer practices such as peptides, NAD, and red light therapy

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21:18

Exosomes 101: The Truth About Cellular Messaging in...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2025/12/17

Many listeners asked us to go deeper into exosomes, and this episode expands on everything that most brands avoid talking about: count, consistency, purity, and microRNA composition. We explain why exosomes on a label don’t mean much without verified numbers, and how dose shapes whether the skin actually receives a biologically meaningful message.We walk through why platelet-derived exosomes offer the clearest communication to human skin, why microRNAs matter more than growth factors alone, and how

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22:23

Exosomes 101: The Truth About Cellular Messaging in...

Biohacking Beauty: The Anti-Aging Skincare Podcast ·

2025/12/10

Many listeners have been curious about exosomes, and this episode offers a simple, science-based foundation for understanding them. We explore what exosomes are, how they act as communication packets between cells, and why they play such an important role in skin rejuvenation.We walk through the three main categories of exosomes found in skincare, plant, stem cell, and platelet-derived, and discuss how each behaves differently inside the skin. We explain what happens when cellular signals weaken

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