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PODCAST

Rapid Response RN

Sarah Lorenzini

Do you want to go from dreading emergencies to feeling confident and ready to jump into action to rescue your patient? Well, this show will let you see emergencies unfold through the eyes of a Rapid Response Nurse. With real life stories from the frontlines of nursing, host Sarah Lorenzini MSN, RN, CCRN, CEN, a Rapid Response Nurse and educator, shares her experiences at rapid response events and breaks down the pathophysiology, pharmacology, and the important role the nurse plays during

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All Episodes

37:22

160: The 2026 AHA/ACC New PE Guidelines with Dr. Mark...

Rapid Response RN ·

2026/04/10

The AHA just updated the playbook on acute pulmonary embolism. The old classification system is gone. Heparin drips are no longer the default. And if your instinct is to push for intubation, that could be the thing that makes your patient worse.In this episode, Dr. Mark Creager, lead author of the 2026 AHA Multi-Society Guideline on Acute Pulmonary Embolism, breaks down exactly what's changed, how the new guidelines help teams make better decisions faster, and what nurses need to know about

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40:21

159: Nurse Led Stroke Alert Process with Kat Siaron RN

Rapid Response RN ·

2026/03/27

"Therehastobeabetterway."We'veallthoughtit.Thisepisodeisproofthatnursescanbetheonestomakeithappen.Inthisepisode,SarahisjoinedbyKatSiaron,rapidresponsenurseandco-authoroftheRRTSTARstudythatshowswhathappenswhennursesareempoweredtoactbeforeaclearstrokediagnosisismade.Theywalkthroughapatientcasethatexposedadangerousgapininpatientstrokeresponse,trapslikesedationhangoverthatmaskstrokepresentations,andhowthenurse-ledCodeStrokeprocesshasdrasticallyimprovedtimetocrucialintervention.You'llhearaboutthestep-by-s

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32:29

158: What’s Changed in Acute Stroke Care? New AHA...

Rapid Response RN ·

2026/03/13

The stroke guidelines just changed and it’s exciting and nuanced! What you do in the first 30 minutes could drastically change your patient's outcome. In this episode, Dr. Shyam Prabhakaran, neurologist and chief writer of the new 2026 AHA Stroke Guidelines, explains what's changed and how these guidelines are changing practice at the bedside.Stroke treatment decisions are getting faster, more nuanced, and more imaging-driven. Inclusion/exclusion criteria and whether to give thrombolytics, who is a

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51:27

157: Cracking the ARDS Code: A Deep Dive on ARDS Vent...

Rapid Response RN ·

2026/02/28

ARDS is one of the more complex syndromes we manage in critical care. More than just pulmonary edema, we are battling stiff lungs, refractory hypoxemia, rising pressures, and frequently making decisions that can either protect the lung or make things worse.In this episode, I’m joined by respiratory therapist Melody Bishop for a deep dive into ARDS ventilator management through the lens of physiology, evidence, and real bedside practice. We break down what’s actually happening in the lung, why some

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27:37

156: When the Body Rejects the Cure: Graft Verses...

Rapid Response RN ·

2026/02/13

A transplant saves a life… but can also make the body attack itself. That's what Graft Versus Host Disease (GVHD) does, and why nurses need to catch it early. You may have never seen it before, but this episode will tell you what it looks like at the bedside and the early clues you can’t afford to miss.Through a real patient case, Anthony, RN explains why GVHD is easy to overlook, how to think through common differentials, and what matters most when it comes to helping patients stabilize and

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43:59

155: Rewinding the Clock: Teamwork That Prevents the...

Rapid Response RN ·

2026/01/30

You know those moments when something just “feels off?” That’s when you should trust your instincts and speak up because timing can completely change a patient’s outcome.In this episode, Sarah is joined by Dr. Oscar Mitchell, Associate Director of the Center for Resuscitation Science and Director of the Medical Rapid Response Team at the Hospital of the University of Pennsylvania. They break down one septic shock case across two timelines: first, when rapid response is called early and there's still

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47:56

154: Physiology-Guided Sepsis Resuscitation:...

Rapid Response RN ·

2026/01/16

The science is finally catching up to what clinicians have long known: more fluids aren't always the answer to septic shock. In this episode, host Sarah Lorenzini and Jaclyn Bond MSN-LM, MBA-HM explain what the ANDROMEDA-SHOCK 2 trial reveals about physiology-guided sepsis resuscitation and why fixed-volume fluid strategies can lead to avoidable harm.They break down how dynamic fluid responsiveness testing helps teams stop guessing, and how tools like FloPatch support real-time assessment of carotid

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26:54

153: Remix: Managing Crashing Pulmonary Embolism...

Rapid Response RN ·

2026/01/02

Pulmonary embolisms don’t always announce themselves... sometimes they ambush. One minute your patient is walking with physical therapy, the next they’re hypotensive, hypoxic, and coding. This re-released early episode dives deep into why PE patients can look deceptively stable… right up until they aren’t.In this episode, I revisit one of my earliest case-based teachings on pulmonary embolism, updated with an added segment on vasopressin use in obstructive shock from PE. Through real bedside stories

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55:28

152: "Don't Touch That Button!" Respiratory Wisdom,...

Rapid Response RN ·

2025/12/19

Some of the most common respiratory myths are still showing up at the bedside. But it's not your fault — most of us were never taught what an oxygenation problem versus a ventilation problem looks like in real time.In this episode, Melody Bishop RT explains how respiratory therapists think through oxygenation and ventilation to choose the right intervention and recognize when a patient is ready to breathe on their own. We’re calling out the old dogma and myths that can delay treatment and worsen

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30:20

151: Caring Close to Home: How Point-of-Care EEG and...

Rapid Response RN ·

2025/12/05

Rural nursing is anything but simple. They have limited resources, fewer specialists, and often have to send patients hours away from their families for a higher level of care. But all that is changing as new tech like Zeto brings monitoring right to the bedside and keeps more patients close to home.In this episode, ICU nurse leader Kristen RN shares how point-of-care EEG has empowered her team to catch subclinical seizures sooner and make faster, more informed clinical decisions. From buy-in to

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48:04

150: Sepsis-Induced Cardiomyopathy with Dr. Mahmoud...

Rapid Response RN ·

2025/11/21

Your pneumonia patient is hypotensive, tachycardic, and not responding to fluids… what did you miss? It could be sepsis-induced cardiomyopathy, a common under-recognized shock state you could see at the bedside.In this episode, Dr. Mahmoud Ibrahim MD and host Sarah Lorenzini use a case study to highlight how nurses, intensivists and the ICU team can work together to recognize the signs of sepsis-induced cardiomyopathy early and give patients a better chance at recovery. You'll learn the diagnostic

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55:54

149: Inside the New 2025 AHA Resuscitation...

Rapid Response RN ·

2025/11/07

Every five years, resuscitation guidelines get a refresh. This year, a few have changed, many have stayed the same, and some are creating major controversy.In this episode, Dr. Ashish Panchal, Chair of the AHA Emergency Cardiovascular Care Committee, helps us unpack what’s new, what might surprise you, and the science behind each decision. You'll learn why there’s serious debate around epinephrine dosing, what changes matter most for the bedside, and how these updates will change the way you and

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36:01

148: Differentiating Pulmonary Hypertension vs...

Rapid Response RN ·

2025/10/24

Differential diagnosis is part physiology, part detective work. Especially in heart failure, where similar vital signs can mean very different things.In this episode, Natalie RN is back on the show to break down two pediatric cases that looked almost identical on arrival to the ED but their workups led to two very different treatment plans. She shares the assessment findings, diagnostics, and clinical clues that helped them uncover what was really going on.Learn how to connect the dots and find the

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57:22

147: Recognize, Decompress, Stabilize: Managing a...

Rapid Response RN ·

2025/10/10

Every trauma nurse knows this feeling: your stable patient suddenly starts to decompensate and instinct tells you there’s more to the story. Today’s case starts with a stable, post-arrest patient and ends in a full-blown tension pneumothorax.Hear why this patient went from stable to crashing in minutes, how delayed recognition changed the course of care, what diagnostics and assessments could have caught earlier. Trauma Pete breaks down the tell-tale signs, how it differs from a simple pneumothorax,

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44:26

146: From Alveoli to Aftermath: The Science and...

Rapid Response RN ·

2025/09/26

This is one of those cases that tests you in every way as a nurse. A toddler is pulled out of a pool and rushed to the ER, unresponsive and deteriorating fast. Today, Nurse Amber walks us through the critical moments that followed and how this case inspired her to turn her grief into a positive resource for nurses.We discuss what was going on at the alveolar level in this patient, the interventions Amber and her team performed, and the emotional aftermath of working on critical pediatric patients

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37:36

145: Genetic Arrhythmogenic Cardiomyopathy: Sarah and...

Rapid Response RN ·

2025/09/12

Some conditions hide in your genes, without any symptoms. One of these conditions is genetic arrhythmogenic cardiomyopathy, an inherited condition that can lead to sudden cardiac arrest — even if you feel completely fine.In this episode, Sarah and Leslie talk about their shared diagnosis of FLNC cardiomyopathy — from how this gene mutation affects the function of the heart to how they're managing this rare condition. You'll hear how Leslie's ICD has saved her life more than once, how it feels to be

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52:10

144: Trauma Plus: Navigating Complex Trauma Care with...

Rapid Response RN ·

2025/08/29

What happens when a trauma patient isn’t just a trauma patient? In today’s episode, we’re diving into “Trauma Plus” — those high-stakes situations where comorbidities, medications, environmental exposures, or underlying medical emergencies complicate recognition of decompensation and change everything about how we care for our patients.I’m joined by Flight Nurse Gwenny, who brings her expertise from the field to walk us through three complex trauma cases where things aren’t what they first appear to

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49:58

143: Neonatal Cardiogenic Shock: What Every Pediatric...

Rapid Response RN ·

2025/08/15

Why would a healthy newborn suddenly stop eating and start vomiting? When a fussy baby comes into the ER, it's easy to assume it's nothing urgent — like colic or gas. But in today's case, there were small signs that pointed to something more.This episode unpacks the high-risk condition and treatment of neonatal cardiogenic shock with Natalie Pleiman, pediatric nurse and clinical coach. From the early (often misleading) signs to critical assessments, you'll learn what makes cardiogenic shock

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01:06:12

142: High Risk PCI for STEMI With Guests Sarah Vance...

Rapid Response RN ·

2025/08/01

One unstable patient, three departments, and every nurse on alert... Let's break down what really happens during a high-risk STEMI. This episode follows the case of a 62-year old patient from ER to the Cath Lab to the ICU. Nurses Sarah Vance and Caitlyn Nichols help us explore the role of nurses in each stage of care, from stabilizing the patient to placing an Impella device.We cover everything from IV placement and medications to monitoring patients through each phase of care. Learn how to prepare

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26:17

141: Hypertrophic Cardiomyopathy: Why Bigger is NOT...

Rapid Response RN ·

2025/07/18

Often, the first symptom of hypertrophic cardiomyopathy is sudden death. But sometimes, we get a warning— and that’s where clinical judgment at the bedside saves lives.Today, Sarah goes over the case of her patient Ben, a 20-year-old experiencing syncope and chest pain. As his condition quickly deteriorated, the team had to carefully manage the patient before reaching a diagnosis of hypertrophic cardiomyopathy. Hear what pointed them to this diagnosis, why some standard interventions can be

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165 results

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