The Matter Blotter

In this short audio, I reflect on the release of El Agente and El Agente Cuántico, thank the team that made them possible, and invite the scientific community to help shape what comes next. Rather than outlining our internal roadmap, I ask chemists, materials scientists, and computational researchers to share which agentic workflows they truly want—especially the tasks that are slow, fragile, or unnecessarily complex today. The goal is to build agentic systems that solve real scientific pain points,

In this podcast, I reflect on a call to arms to the emerging area of agents for science. Benchmarking is crucial for all of us to build a strong and transparent field. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit aspuru.substack.com

In this second episode of our podcast, we discuss our recent paper Keeping it Simple: Language Models can learn Complex Molecular Distributions with Daniel Flam-Shepherd. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit aspuru.substack.com

Hi Matter Blotter readers (and now listeners!) This is my first attempt at creating a simple podcast. I aim to have 5-minute clips with minimal editing to make them pleasant to listen to. I finally bit the bullet and bought a subscription to Adobe Creative Cloud and I am using Adobe Audition. I am reacting to the announcement of inSilico AI about the first-in-human trials of an AI-discovered drug and target.Some links to some of the things I mention in the podcast.* Our 2019 paper with inSilico*