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PODCAST

The Brain Podcast

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals. The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists

science life sciences

All Episodes

22:11

Neurotransmitter-informed connectivity maps and...

The Brain Podcast ·

2025/11/26

Welcome to the 32th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author Dr Philipp J Koch of the Brain article entitled: Neurotransmitter-informed connectivity maps and their application for outcome inference after stroke We discuss a fascinating method to map neurotransmitter-informed brain network maps. From here, the authors examine two separate stroke cohorts and examine the degree of

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22:18

Do seizures drive the neuropathology of dementia?...

The Brain Podcast ·

2025/10/22

Welcome to the 31th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author Dr Ifrah Zawah of the Brain article entitled: The association of seizure control with neuropathology in dementia We discuss an impressive post-mortem investigation of the link between seizures and the associated neuropathology of dementia. Higher tau and beta-amyloid burden is associated with Alzheimer's disease and also other

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25:36

Investigating autoimmune mechanisms underlying...

The Brain Podcast ·

2025/09/25

Welcome to the 30th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Professor Gabor G Kovacs of the Brain article entitled: Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy Listen to the fascinating insights exploring the autoimmune side of progressive supranuclear palsy (PSP) following identification of cytotoxic T cells within the mid-brain

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20:34

Can transcriptional analysis detect efficient...

The Brain Podcast ·

2025/08/20

Welcome to the 29th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author of the Brain article entitled: Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis We are joined by Alida Chen for an interesting discussion into detecting transcriptional changes that may identify efficient remyelination in multiple sclerosis. Using brain bank donor tissue, the

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36:36

Nephrology Meets Neurology: how kidney health links...

The Brain Podcast ·

2025/06/25

Welcome to the 28th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with three authors of the Brain article entitled: The relationship between kidney health and neurodegenerative diseases Ms Melody Zuo, Dr Le Chang and Professor Sarah A Gagliano Taliun grace the Brain podcast with an insightful discussion into their recent review examining the connection between kidney disease and neurogeneration. They describe

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24:48

Understanding traumatic brain injury with high...

The Brain Podcast ·

2025/05/14

Welcome to the 27th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author Dr Lucia M Li of the Brain article entitled: High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury Listen to the fascinating insights into classifying traumatic brain injury (TBI) using high dimensional proteomic analysis. TBI may start with a head injury but evidence suggests that

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32:51

Glymphatic homeostasis in heart failure- more in but...

The Brain Podcast ·

2025/04/16

Welcome to the 26th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author Dr Marios Kritsilis and senior author Associate Professor Iben Lundgaard of the Brain article entitled: Loss of glymphatic homeostasis in heart failure This academic duo from Lund University discuss their fascinating findings exploring glymphatic homeostasis in a mouse model of heart failure. Counter-intuitively, there may be

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21:37

Adult congenital myasthenic syndromes - discussing...

The Brain Podcast ·

2025/02/27

Welcome to the 25th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Tanya Stojkovic of the Brain article entitled: Congenital myasthenic syndromes in adults: clinical features, diagnosis and long-term prognosis Dr Stojkovic discusses findings from an impressive longitudinal adult cohort of congenital myasthenia syndrome and important issues around accurate diagnosis of congenital myasthenic

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38:00

Nociceptors are functionally male or female: from...

The Brain Podcast ·

2025/01/22

Welcome to the first episode of 2025 for The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Frank Porreca of the Brain article entitled: Nociceptors are functionally male or female: from mouse to monkey to man? Dr Porreca discusses important findings into the sexual dimorphic nature of nociception and how it could and indeed should affect clinical trial participant design, precision medicine and need for

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28:59

Academic neurology in the UK: a plea to turn away...

The Brain Podcast ·

2024/12/11

Welcome to the 23nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode, we bring on authors Dr Helen Devine and Professor Simon Mead to discuss their opinion article entitled: Academic neurology in the UK: a plea to turn away from the precipice. The discussions covers the growing concerns regarding the future of academic neurology in the UK and potential solutions. They discuss the parallels seen around the world as this is a growing

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27:52

Can Epilepsy surgery improve or even reverse...

The Brain Podcast ·

2024/10/16

Welcome to the 22nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Torsten Baldeweg of the Brain article entitled: Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline? Dr Baldeweg discusses fascinating insight into the long term cognitive outcomes from an impressively large cohort of 500 children who had undergone epilepsy surgery and

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34:26

Anti-IgLon5 disease risk is mediated by HLA-DQB1*05...

The Brain Podcast ·

2024/08/14

Welcome to the 21th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with the first author Dr Selina Yogeshwar of the Brain article entitled: HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease Dr Yogeshwar offers exciting insight into the genetic mechanisms of a relatively recently discovered disease anti-IgLON5. She also discusses foundational information into how neuroimmunology,

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25:44

The essential Role of PAK2 in Myelinating the...

The Brain Podcast ·

2024/06/20

Welcome to the 20th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with the final author Dr Jun Li of the Brain article entitled: PAK2 is necessary for myelination in the peripheral nervous system How are peripheral nerve cells myelinated and what proteins are invoved? Is there a difference between PAK1 and PAK2? Listen for this and more in this exciting episode. Check out the full article on the Brain website:

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29:18

How is the gut microbiota related to cognition and...

The Brain Podcast ·

2024/05/15

Welcome to the 18th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author author Dr Stefanie Grabrucker of the Brain article entitled: Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis How does lifestyle and the environment affect cognition in Alzheimer's disease via the gut and what can we do about it? Listen for this and more in this exciting episode

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22:38

Do noradrenergic alterations in Parkinson’s disease...

The Brain Podcast ·

2024/04/03

Welcome to the 17th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Bénédicte Ballanger of the Brain article entitled: Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study Can this multi-modal study examining the role of Noradrenaline in Parkinson's disease offer insight into important neurotrasmitter pathophysiology and provide the basis for

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16:08

Altered brain glucose metabolism as a mechanism for...

The Brain Podcast ·

2024/02/14

Welcome to the 16th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. We are very excited to feature a January issue Brain article, where we speak with senior author Dr Lasse M Giil entitled: Impaired glucose utilization in the brain of patients with delirium following hip fracture Delirium is a common condition with significant impact on patient outcome. This episode discussed potential intrinsic brain mechanisms that may underly delirium. The

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19:35

Are there differences in the immune response among...

The Brain Podcast ·

2023/11/15

Welcome to the 15th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. We are very excited to feature our first article from Brain Communications, where we speak with first author Dr Kiel Telesford of the article entitled: Neuron-binding antibody responses are associated with Black ethnicity in multiple sclerosis during natalizumab treatment This episode discussed racial differences in antibody response to natalizumab treatment for individuals of

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20:12

Exploring a genetic basis for disordered speech and...

The Brain Podcast ·

2023/10/11

Welcome to the 14th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Fu-Chin Liu, senior author of the article entitled: Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons. This article explores a potential genetic basis for disordered speech by a mutation in the transcription factor FOXP2. This was discovered in KE family members with speech disturbances was a landmark example of

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28:29

Multisite thalamic recordings to characterize seizure...

The Brain Podcast ·

2023/09/13

Welcome to the 13th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Josef Parvizi, senior author of the article entitled: Multisite thalamic recordings to characterize seizure propagation in the human brain This article explores the role of the thalamus in seizure propagation and how multi-site intracranial electrode recordings identify new and unexpected findings regarding which thalamic nuclei may have the earliest

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16:25

A genome-wide association study in autoimmune...

The Brain Podcast ·

2023/08/14

Welcome to the 12th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Nico Melzer, senior author of the article entitled: A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies This article explores expanding entity of GAD-65 associated neurological syndromes, the exciting role of T-cells and potential therapeutic avenues that these findings may bring. Check out the full

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32 results

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