Oncology Unscripted With John Marshall

00:35:42

Oncology Unscripted With John Marshall: Episode 35:...

Oncology Unscripted With John Marshall ·

2026/09/29

Main TopicIn this episode of Oncology Unscripted, Dr. John Marshall explores how new approaches are shaping cancer treatment decisions, from using AI to help personalize treatment for individual patients to the unexpected results of a randomized trial of adagrasib in colorectal cancer. He also examines how precision medicine may help guide treatment for patients with cancers of unknown primary.MedBuzzIn this MedBuzz, Dr John Marshall examines the rising cost of cancer treatments and the difficult

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00:34:46

Oncology Unscripted With John Marshall: Episode 34:...

Oncology Unscripted With John Marshall ·

2026/08/28

Main TopicIn this episode of Oncology Unscripted, Dr John Marshall reflects on growing vaccine hesitancy and contrasts that with new reports that a personalized melanoma messenger RNA vaccine improved outcomes in a phase 3 study. MedBuzz In this MedBuzz, Dr John Marshall reflects on recent changes in prescription drug pricing and the rapid rise of GLP-1 receptor agonists, their long-term impacts, and how he handles answers to questions from patients about impacts on cancer outcomes. Interview In

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00:13:48

Oncology Unscripted With John Marshall: Episode 33:...

Oncology Unscripted With John Marshall ·

2026/07/29

Main TopicIn this episode of Oncology Unscripted, Dr Marshall examines the evolving role of blood-based cancer screening and highlights new research showing how dogs may help detect early cancers from breath samples. Alternative Data Centers, Medicine, and AI Guilt? In MedBuzz, Dr Marshall discusses the emergence of betting on clinical trial outcomes, the rise of AI in medicine, the environmental impact of data centers, and whether growing reliance on artificial intelligence should leave

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00:40:27

Oncology Unscripted With John Marshall: Episode 32:...

Oncology Unscripted With John Marshall ·

2026/06/29

Main Topic:In this episode of Oncology Unscripted, Dr John Marshall discusses major post-ASCO developments in GI oncology, including new RAS inhibitor data in pancreatic cancer and the path forward. MedBuzz: In this episode of Oncology Unscripted, Dr John Marshall reflects on a trip to South Africa and what it revealed about survival, inequity, and the luxury of modern cancer care. Through experiences in Johannesburg and on safari, he connects cancer care access to broader questions of

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00:12:22

Oncology Unscripted With John Marshall: Episode 31:...

Oncology Unscripted With John Marshall ·

2026/05/27

MedBuzz:In this episode of Oncology Unscripted, John Marshall, MD, discusses a troubling week in health care news, including upheaval at the FDA, concerns about reduced federal support for medical education, and growing evidence that AI-generated fabricated references are appearing in published scientific literature. Main Topic: In this episode of Oncology Unscripted, Dr John Marshall previews the practice-changing data expected at ASCO 2026, highlighting advances in precision medicine. Tune in

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00:31:49

Oncology Unscripted With John Marshall: Episode 30:...

Oncology Unscripted With John Marshall ·

2026/05/21

MedBuzz:In this episode of Oncology Unscripted MedBuzz, Dr Marshall discusses evolving rectal cancer data and the growing role of genomic testing. He also reflects on US science policy and concerns about instability, and the need to modernize clinical trials while protecting independent oversight and patient data. Main Topic: In this episode of Oncology Unscripted, Dr Marshall discusses the growing role of precision medicine in oncology and how it is shifting from an optional tool to a standard

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00:38:23

Oncology Unscripted With John Marshall: Episode 29:...

Oncology Unscripted With John Marshall ·

2026/04/29

MedBuzz:In this MedBuzz, Dr John Marshall discusses Steve Ubl’s departure from PhRMA and what it may signal for drug pricing, pharmaceutical policy, payer dynamics, and patient access. Main Topic: In this episode of Oncology Unscripted, Dr John Marshall explores the growing role of AI in cancer care, from analyzing patient data and predicting treatment responses to supporting clinical trials, guidelines, manuscripts, and patient communication. He also reflects on the risks of AI, including

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00:30:16

Oncology Unscripted With John Marshall: Episode 28:...

Oncology Unscripted With John Marshall ·

2026/03/25

MedBuzz:After a trip to the Galapagos, Dr John Marshall reflects on evolution in nature, cancer, and medicine. From Darwin’s observations to the rise of AI and precision oncology, he explores how rapidly cancer adapts, how technology is reshaping care, and why the future of medicine must still preserve the human touch. Main Topic: In this episode of Oncology Unscripted, Dr John Marshall reflects on a practice-changing cholangiocarcinoma study from China and what it reveals about the rapid

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00:33:03

Oncology Unscripted With John Marshall: Episode 27:...

Oncology Unscripted With John Marshall ·

2026/02/23

MedBuzz:Watch now as Dr Marshall discusses the growing instability at the FDA, including job cuts, leadership turnover, and structural reorganization. Main Topic: This episode of Oncology Unscripted explores the projected $25 trillion global cost of cancer care, rising cancer incidence, and declining mortality, all set against political and funding uncertainty in frozen Washington, DC. Interview: In this episode of Oncology Unscripted, John Marshall, MD, sits down with Richard Pazdur, MD,

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00:33:31

Oncology Unscripted With John Marshall: Episode 26:...

Oncology Unscripted With John Marshall ·

2026/01/28

Oncology Unscripted at ASCO GI: People, Pipelines, and PrecisionJohn Marshall, MD:Hello, everybody, from San Francisco, California. My name is Dr. John Marshall, and you are on—maybe unwisely—Oncology Unscripted. But thanks for joining me. I love this meeting, but let's first talk about the news of 2026.Top of the line is: we're out to get new countries. Now, I'm sort of running for mayor of Havana. I don't know if it's important that I, in fact, speak Spanish—because I don't. I speak a little bit

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00:22:20

Oncology Unscripted With John Marshall: Episode 25:...

Oncology Unscripted With John Marshall ·

2025/12/18

MedBuzzTariffs, Taxes, and Trade-Offs: Can Raising Taxes in the UK Get You Cheaper Drugs in the US?John Marshall, MD: John Marshall for Oncology Unscripted. There's been all sorts of stuff going on out there in healthcare—in the business of healthcare—and a recent article that was just published in The New York Times told us something about the relationship between the National Health Service, how patients get access to drugs there in Great Britain, and our relationship with them and the tariffs

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00:23:34

Oncology Unscripted With John Marshall: Episode 24:...

Oncology Unscripted With John Marshall ·

2025/12/15

MedBuzz: From Hormones to Heroines: Couric, Cancer, and the Case for ChangeJohn Marshall, MDHello, everybody. John Marshall for Oncology Unscripted, coming to you from my now almost empty office. I've been in this office for, gosh, 20-plus years. It's the big office. You may or may not know I stepped down as the division chief here at Georgetown. We planned it—I wanted to do it a while ago. They said no. So, I finally got to step down because I wanted to do some other things. I get a lot of time

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00:33:14

Oncology Unscripted With John Marshall: Episode 23:...

Oncology Unscripted With John Marshall ·

2025/11/18

MEDBUZZ [0:00:05]When the Sources of Trusted Information Change—Who Do We Believe?John Marshall, MD:Happy whatever day it is today when you're watching this. John Marshall for Oncology Unscripted. A little bit of a rainy day here in Washington, DC. It's been a little bit of a weird time here in Washington, DC—even weirder than it normally has been.Let's start with a little of the business of our world today—the business of oncology. You may have seen that we have a new National Cancer Institute

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00:33:14

Oncology Unscripted With John Marshall: Episode 22:...

Oncology Unscripted With John Marshall ·

2025/10/14

[00:00:05] Main Topic ESMO, Efficiency, and Evidence: New Data, China’s Science Leap, and Leucovorin and Autism John Marshall, MD: Hey everybody, John Marshall from Oncology Unscripted. There is so much going on right now that we're gonna need a full hour-long show, but we're not gonna do that to you. We still promise short bites here and there of the stuff that's going on, just to make sure you're in the loop. I'm sure you are.But let's start with a little science. And the science we wanna focus on

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00:20:23

Oncology Unscripted With John Marshall: Episode 21:...

Oncology Unscripted With John Marshall ·

2025/09/16

[00:00:05] MedBuzz: Back to Being ‘Just a Doctor’John Marshall, MD: John Marshall for Oncology Unscripted, coming to you live from this big office. This is the biggest office because, you know, I've been the Chief of the Division here at Georgetown for 20 years. I didn't want the job when I was first offered it a long time ago. I ended up saying yes. Of course, that's a dramatic change in one's academic career—taking on administrative roles like this. You do get the big office, which is nice, but

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00:38:07

Oncology Unscripted With John Marshall: Episode 20:...

Oncology Unscripted With John Marshall ·

2025/08/20

Why Are More Healthy Young Adults Getting GI Cancer?[00:05]John Marshall, MD:John Marshall for Oncology Unscripted. Big paper coming out of _JAMA_—it's actually a review article. Really, really smart people and friends up in Boston looked at this. We all see it: this emerging trend of younger and younger people getting all kinds of cancer. This particular paper wasn’t about all kinds of cancer, but we’re clearly seeing it in GI cancers. We don’t really understand what’s going on, but we see it—it’s

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00:55:05

Oncology Unscripted With John Marshall: Episode 19:...

Oncology Unscripted With John Marshall ·

2025/07/15

ACCESS THROUGH INNOVATION: THE POWER OF SMARTER CANCER CARE STRATEGIES[00:00:05] John Marshall, MD: John Marshall for Oncology Unscripted. Really no script at all, but we are post-ASCO here in Washington, DC, trying to take all of those major innovations that we all get so excited about—curves with big deltas that we saw in all sorts of different cancers, including the humblest of them all: GI cancers.So, now the question is: how do you take those innovations and those changes—some of them are added

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00:11:27

Oncology Unscripted With John Marshall: Episode 18:...

Oncology Unscripted With John Marshall ·

2025/06/10

“Badge-up” with Dr Marshall at ASCO 2025John Marshall, MD: John Marshall coming to you live Oncology Unscripted, not from my office back in Georgetown, but from beautiful downtown Chicago, Illinois at ASCO 2025. Look at this amazing place. 40,000 of our closest friends.To get in, you need to have one of these. So, I'm gonna go ahead and badge up. I got a fancy red collar thing here, boy, that makes me stand out even that much more.But what we're gonna talk about today first is the social aspect. You

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00:32:16

Oncology Unscripted With John Marshall: Episode 17:...

Oncology Unscripted With John Marshall ·

2025/05/28

Badges, Booths, and Buses: Welcome to ASCO 2025John Marshall, MD: John Marshall Oncology Unscripted. You know what this is? Yeah. You know what this is. This is my ASCO badge. It is that time of year again where I. I don't know, 40, 50, 60,000 of us and our closest friends all fly up to Chicago, stay in hotels that are overpriced, get bused around downtown Chicago, even on Saturday and Sunday. We get in nice clothes. We go to the convention center. We probably share a virus or two, but we mostly

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00:34:33

Oncology Unscripted With John Marshall: Episode 16:...

Oncology Unscripted With John Marshall ·

2025/05/12

No Evidence of Disease—No Need for the Knife?John Marshall, MD: John Marshall for Oncology Unscripted. Let's talk a little science and cancer medicine. I’m gonna come at you from a little bit of a different angle. Yep. A GI cancer angle, but a little bit different.We have long felt in order to cure GI cancers, we had to do surgery, that it was the only way to ultimately cure people. But we all know that when we do neoadjuvant something could be chemo chemoradiation. we operate. A certain sub portion

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