Gynecologic Oncology Update

13:57

HER2-Positive Gynecologic Cancers — Microlearning...

Gynecologic Oncology Update ·

2026/10/07

Featuring perspectives from Dr Joyce F Liu, Dr David M O'Malley and Dr Brian M Slomovitz, moderated by Dr O'Malley, including the following topics:Case: A woman in her mid 60s with Stage II uterine carcinosarcoma treated with surgery followed by paclitaxel/carboplatin, whole-pelvic radiation and vaginal cuff brachytherapy — Dr Angeles Alvarez Secord (0:00)Case: A woman in her mid 50s with ovarian cancer and a genomic instability score of 50, folate receptor alpha 90%, HER2 IHC 2+, and BRCA1/2

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23:25

HER2-Positive Gynecologic Cancers — Microlearning...

Gynecologic Oncology Update ·

2026/10/01

Featuring perspectives from Dr Joyce F Liu, Dr David M O'Malley and Dr Brian M Slomovitz, moderated by Dr O'Malley, including the following topics:Case: A woman in her mid 60s with metastatic serous endometrial carcinoma that is HER2 IHC 3+ who received first-line carboplatin/paclitaxel/trastuzumab and second-line trastuzumab deruxtecan — Ursula Matulonis, MD (0:00)Commentary: Role of HER2-directed therapy in the maintenance setting for patients with HER2-positive disease — Professor Jonathan A

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51:21

Ovarian and Endometrial Cancer — Proceedings from a...

Gynecologic Oncology Update ·

2026/09/30

Featuring perspectives from Dr Shannon N Westin and Dr Stephen "Fred" Divers, moderated by Dr Divers, including the following topics:Introduction (0:00)Ovarian Cancer (2:22)Endometrial Cancer (37:48)CME information and select publications

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48:25

Glucocorticoid Receptor Antagonists for Ovarian...

Gynecologic Oncology Update ·

2026/09/29

Featuring an interview with Professor Nicoletta Colombo, including the following topics:Mechanistic effects and rationale underlying the use of relacorilant/nab paclitaxel (0:00)Rationale underlying the study design of the Phase II BELLA trial and avenues for future exploration (8:31)Definition of platinum ineligibility; importance of platinum-containing chemotherapy for patients with ovarian cancer (14:02)Findings from a Phase II trial and the subsequent confirmatory Phase III ROSELLA study

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09:31

HER2-Positive Gynecologic Cancers — Microlearning...

Gynecologic Oncology Update ·

2026/09/24

Featuring perspectives from Dr Joyce F Liu, Dr David M O'Malley and Dr Brian M Slomovitz, moderated by Dr O'Malley, including the following topic:Case: A woman in her late 50s with a BRCA1 germline mutation and platinum- and PARP inhibitor-resistant metastatic ovarian cancer with low folate receptor alpha level and HER2 IHC 1+ — Professor Jonathan A LedermannCME information and select publications

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58:14

Gynecologic Cancers — Reviewing Key Presentations...

Gynecologic Oncology Update ·

2026/09/17

Featuring perspectives from Dr Gottfried E Konecny and Dr Brian M Slomovitz, including the following topics:Introduction (0:00)Preventing Ovarian Cancer (1:04)Endometrial Cancer (5:27)Ovarian Cancer (25:36)Cervical Cancer (54:04)CME information and select publications

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26:21

Low-Grade Serous Ovarian Cancer — Rapid Case Review:...

Gynecologic Oncology Update ·

2026/09/14

Featuring perspectives from Dr Rachel N Grisham, including the following topics:Case: A woman in her early 40s with recurrent low-grade serous ovarian cancer (LGSOC) and prior treatment with a MEK inhibitor receives avutometinib/defactinib on the RAMP 301 trial (0:00)Case: A woman in her early 70s with recurrent KRAS-mutated LGSOC receives avutometinib/defactinib and develops muscle weakness (10:03)Case: A woman in her late 70s with KRAS-mutated recurrent LGSOC develops congestive heart failure on

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28:46

Low-Grade Serous Ovarian Cancer — 5-Minute Journal...

Gynecologic Oncology Update ·

2026/09/13

Featuring perspectives from Dr Rachel N Grisham, including the following topics:Mechanism, clinical evidence and practical use of avutometinib with defactinib for recurrent low-grade serous ovarian cancer (LGSOC) (0:00)A Phase III trial of letrozole alone as front-line treatment for LGSOC (11:11)Current and future role of avutometinib with defactinib for LGSOC (19:23)A Phase II/III trial of trametinib for recurrent LGSOC: Biomarker analyses and clinical implications (21:37)CME information and select

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20:04

Endometrial Cancer — Microlearning Activity 3:...

Gynecologic Oncology Update ·

2026/09/11

Featuring perspectives from Dr Floor J Backes, Dr Matthew A Powell and Dr Ritu Salani, moderated by Dr Salani, including the following topics:Case: A woman in her late 60s with recurrence of metastatic estrogen receptor-positive endometrial cancer enrolls in a trial of CDK4/6 inhibition with an aromatase inhibitor 1 year into maintenance dostarlimab after carboplatin/paclitaxel/dostarlimab and has no evidence of disease 3 years later (0:00)Adding a PARP inhibitor to immunotherapy and chemotherapy:

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01:31:15

TROP2- and CDH6-Directed ADCs in Gynecologic Cancers...

Gynecologic Oncology Update ·

2026/08/01

Featuring an interview with Dr Ramez Eskander, including the following topics:Overview of antibody-drug conjugates (ADCs) and their role in the management of gynecologic cancers; considerations in sequencing (0:00)Choosing between FRɑ- and HER2-directed ADCs for dually eligible patients; role of antigenic target in predicting efficacy benefit of ADCs (7:53)Comparative efficacy and safety of ADCs and conventional chemotherapy (12:58)Current and investigational targets of ADCs in gynecologic cancers

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01:30:20

For Oncology Nurses: Ovarian Cancer — Proceedings...

Gynecologic Oncology Update ·

2026/07/23

Featuring perspectives from Dr Bradley J Monk, Dr David M O’Malley, Ms Kathryn M Schlenker and Ms Jaclyn Shaver, moderated by Dr O’Malley, including the following topics: Introduction (00:00)Overview of Ovarian Cancer (OC) (2:12)Role of PARP Inhibitors in Advanced OC (4:56)Current and Potential Future Role of Mirvetuximab Soravtansine in OC (28:45)Role of Relacorilant in Advanced OC (57:08)Utility of Immune Checkpoint Inhibition in Advanced OC (1:14:12)NCPD information and select publications

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01:29:57

Endometrial Cancer — Proceedings from a Session Held...

Gynecologic Oncology Update ·

2026/07/20

Featuring perspectives from Dr Floor J Backes, Dr Brian M Slomovitz and Dr Shannon N Westin, moderated by Dr Westin, including the following topics:Introduction (00:00)Current Up-Front Chemoimmunotherapeutic Approaches for Advanced Endometrial Cancer (EC) — Dr Backes (1:50)Current and Future Role of Anti-PD-1/PD-L1 Antibodies in Combination with Systemic Therapies Beyond Chemotherapy for Advanced EC — Dr Westin (33:15)Promising Agents Under Investigation for EC — Dr Slomovitz (1:01:41)CME

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02:01:19

Ovarian Cancer — Proceedings from a Session Held in...

Gynecologic Oncology Update ·

2026/07/15

Featuring perspectives from Dr Ramez N Eskander, Dr Ursula Matulonis, Dr Kathleen N Moore, Dr Alexander B Olawaiye and Dr David M O'Malley, moderated by Dr Moore, including the following topics:Introduction (00:00)Current Role of PARP Inhibitors in the Management of Advanced Ovarian Cancer (OC) — Prof Eskander (2:40)Strategies Targeting Folate Receptor Alpha in Advanced OC — Dr Matulonis (27:41)Other Approved and Promising Investigational Antibody-Drug Conjugates for Advanced OC — Dr Moore

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15:08

Endometrial Cancer — Microlearning Activity 2:...

Gynecologic Oncology Update ·

2026/07/12

Featuring perspectives from Dr Floor J Backes, Dr Matthew A Powell and Dr Ritu Salani, moderated by Dr Salani, including the following topics:Case: A woman in her late 60s presents with mismatch repair-deficient metastatic endometrial cancer(00:00)Perspectives on neoadjuvant immunotherapy for microsatellite instability-high endometrial cancer (06:25)CME information and select publications

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11:23

Endometrial Cancer — Microlearning Activity 1:...

Gynecologic Oncology Update ·

2026/07/10

Featuring perspectives from Dr Floor J Backes, Dr Matthew A Powell and Dr Ritu Salani, moderated by Dr Salani, including the following topics:Case: A woman in her late 70s with de novo metastatic mismatch repair-proficient metastatic endometrioid endometrial cancer (00:00)Molecular analyses in the assessment and management of endometrial cancer (07:33)CME information and select publications

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56:05

Endometrial Cancer — An Interview with Dr Floor J Backes

Gynecologic Oncology Update ·

2026/07/07

Featuring an interview with Dr Floor J Backes, including the following topics:Overview of the treatment landscape of endometrial cancer (00:00)Immunotherapy for advanced endometrial cancer (03:58)Contraindications for immunotherapy (18:15)PARP inhibitors for endometrial cancer (20:12)Management of localized endometrial cancer (28:23)Novel strategies under investigation for endometrial cancer (42:27)CME information and select publications

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01:28:54

For Oncology Nurses: Strategies to Safely and...

Gynecologic Oncology Update ·

2026/07/06

Featuring perspectives from Ms Courtney Arn, Ms Jamie Carroll, Dr Edward B Garon, Dr Heather McArthur and Dr Kathleen N Moore, moderated by Dr Moore, including the following topics:Introduction (0:00)Overview of Antibody-Drug Conjugates (ADCs) (2:07)Current and Future Role of HER2-Targeted ADCs for Breast Cancer (6:23)Currently Available ADCs for Gynecologic Cancer Management (26:37)Currently Available ADCs for Lung Cancer Management (44:07)Current and Future Role of TROP2-Targeted ADCs for

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01:28:13

For Oncology Nurses: Endometrial Cancer — Proceedings...

Gynecologic Oncology Update ·

2026/06/24

Featuring perspectives from Dr Dana M Chase, Ms Sarah Karpen, Dr J Alejandro Rauh-Hain and Ms Jaclyn Shaver, moderated by Dr Chase, including the following topics:Introduction: Biology of Endometrial Cancer (EC) (0:00)First-Line Therapy for Advanced or Recurrent EC (14:15)Potential Benefits of PARP Inhibition Combined with Immunotherapy in Advanced EC (35:13)Role of Lenvatinib/Pembrolizumab in the Management of Progressive Advanced EC (57:48)Other Nursing Considerations in the Care of Patients with

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54:28

Ovarian Cancer — Fifth Annual National General...

Gynecologic Oncology Update ·

2026/06/19

Featuring perspectives from Dr Deborah K Armstrong and Dr David M O’Malley, including the following topics: Introduction (0:00)PARP Inhibitors and Strategies Targeting Folate Receptor Alpha in Advanced Ovarian Cancer — Dr Armstrong (4:37)Other Novel Agents and Strategies for the Treatment of Advanced Ovarian Cancer — Dr O’Malley (35:18)CME information and select publications

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01:27:59

HER2-Positive Gynecologic Cancers — Proceedings from...

Gynecologic Oncology Update ·

2026/06/17

Featuring perspectives from Dr Joyce F Liu, Dr David M O’Malley and Dr Brian M Slomovitz, moderated by Dr O’Malley, including the following topics:Introduction (0:00)Strategies to Identify Patients with HER2-Positive Gynecologic Cancers — Dr Liu (2:52)Available Data with and Practical Application of HER2-Targeted Therapy in Advanced Gynecologic Cancers — Dr Slomovitz (25:16)Identification and Management of Adverse Events with Trastuzumab Deruxtecan — Dr O’Malley (1:00:31)CME information and select

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