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PODCAST

Parkinson Weekly

Parkinson Weekly is your go-to podcast for the latest insights in Parkinson’s disease. Each week, Professor Bas Bloem, Consultant Neurologist in the Department of Neurology at Radboud University Medical Center, Nijmegen, takes you through his chosen “Article of the Week” – highlighting new research, clinical perspectives, and what it means for patients, carers, and healthcare professionals.Have a question you’d like Bas to answer on the podcast? Email us at parkinsonweekly@gmail.com – we’d love to

health & fitness medicine

All Episodes

22:13

EP 28 - The Parkinson Weekly Helpdesk

Parkinson Weekly ·

2026/04/20

🎙️ We’re back with the twenty-eighth episode of Parkinson Weekly, hosted by Bas Bloem. In Episode 28, we introduce a brand-new segment — the Parkinson Weekly Helpdesk — where Prof. Bloem answers listener-submitted questions from across the global Parkinson’s community. Following an overwhelming response, this new format tackles three key questions per episode, offering practical, evidence-based insights while ensuring advice remains general and applicable to all. This first Helpdesk episode

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12:31

EP 27 - Parkinsonism and Related Disorders

Parkinson Weekly ·

2026/04/09

🎙️ We’re back with the twenty-seventh episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In Episode 27, Prof. Bloem explores an intriguing and under-researched question in Parkinson’s disease: can temperature influence symptoms? Inspired by a 2024 study published in Parkinsonism and Related Disorders by Nahid Mohammadzadeh & Joseph Friedman the episode examines how exposure to cold may worsen tremor in people with Parkinson’s disease. Drawing on both clinical observations and

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16:15

EP 26 - Article Of The Week: Clinical severity in...

Parkinson Weekly ·

2026/04/01

🎙️ We’re back with the twenty-sixth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In Episode 26, Prof. Bloem explores a thought-provoking shift in how we understand Parkinson’s disease progression. Inspired by a 2024 study published in Brain by Martin Johansson and colleagues, the episode examines whether we may have been focusing too heavily on the substantia nigra — and overlooking the crucial role of the brain’s cortex. Drawing on data from the Parkinson Precision Project, the

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18:28

EP 25 - Article Of The Week: The impact of diet on...

Parkinson Weekly ·

2026/03/27

🎙️ We’re back with the twenty-five episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In Episode 25, Prof. Bloem explores the complex and evolving role of diet in the risk of developing Parkinson’s disease. Inspired by a recent study published in the Journal of Parkinson’s Disease (2026) by Angelo Gigante and colleagues, the episode examines how different dietary patterns may influence Parkinson’s risk alongside established environmental and genetic factors. Prof. Bloem discusses

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18:56

EP 24 - Article Of The Week: Spiritual Assessment of...

Parkinson Weekly ·

2026/03/19

🎙️ We’re back with the twenty-fourth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In Episode 24, Prof. Bas Bloem discusses an important and often overlooked topic in Parkinson’s care: spirituality. Inspired by a recent paper published in Neurology Clinical Practice (2026) by Dr Indu Subramanian and colleagues, the episode explores how spirituality — the search for meaning, purpose, and connection — can help people living with Parkinson’s disease cope with the challenges of

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28:13

EP 23 - Papers on 'Response Fluctuations'

Parkinson Weekly ·

2026/03/12

🎙️ We’re back with the twenty third episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In Episode 23 of Parkinson Weekly, Prof. Bas Bloem explores the phenomenon of response fluctuations, where the benefits and side effects of oral Parkinson’s medications vary throughout the day. Rather than focusing on a single new study, this episode revisits several influential papers that have reshaped how clinicians understand these fluctuations and their underlying mechanisms. Listeners will learn

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18:48

EP 22 - Article Of The Week: Dual-Risk axis: GBA1...

Parkinson Weekly ·

2026/02/26

🎙️ We’re back with the twenty second episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas explores the role of gene–environment interactions in Parkinson’s disease, examining why some individuals develop Parkinson’s following environmental exposure while others do not. Discussing a recent study published in the Journal of Parkinson’s Disease, he reviews new evidence linking GBA1 genetic mutations with occupational pesticide exposure, highlighting how genetic susc...

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12:49

EP 21 - Article Of The Week: Hearing Loss in...

Parkinson Weekly ·

2026/02/19

🎙️ We’re back with the twenty first episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas explores a surprising and often overlooked question: is hearing loss part of the Parkinson’s disease phenotype? Discussing a 2026 systematic review and meta-analysis published in Movement Disorders, he highlights compelling evidence that hearing impairment is common in Parkinson’s — affecting nearly 80% of patients across pooled studies. High-frequency hearing loss was

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12:46

EP 20 - Article Of The Week: Exploring the impact of...

Parkinson Weekly ·

2026/02/12

🎙️ We’re back with the twentieth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas discusses Exploring the impact of Parkinson’s disease on driving: a population-based survey, a large real-world study examining how Parkinson’s affects driving ability, licence retention, and conversations between patients and healthcare professionals. Driving is closely tied to independence, identity, and quality of life — yet both motor and non-motor symptoms of Parkinson’s can

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15:12

EP 19 - Parkinson’s disease: cognitive challenges and...

Parkinson Weekly ·

2026/02/05

🎙️ We’re back with the nineteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas shines a light on an often overlooked aspect of Parkinson’s disease: cognitive challenges and the practical “detours” people use to navigate them in daily life. He pays tribute to the late Marina Noordegraaf — artist, advocate, and person with Parkinson’s — whose pioneering work helped make these invisible thinking obstacles visible. Building on her earlier work around motor

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18:23

EP 18 - Article Of The Week: Effect on Dyskinesia of...

Parkinson Weekly ·

2026/01/29

🎙️ We’re back with the eighteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas discusses new evidence on an old drug: amantadine. He reviews the PREMANDYSK study, a large multicentre, randomised, placebo-controlled trial conducted across 15 specialist centres in France and published in Movement Disorders, which investigated whether early use of amantadine can delay or prevent the development of levodopa-induced dyskinesias in people with Parkinson’s disease.

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29:36

EP 17 – Article Of The Week: Incidence and Spatial...

Parkinson Weekly ·

2026/01/22

🎙️ We’re back with the seventeenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. Bas discusses the Article of the Week: Incidence and Spatial Variation of Parkinson’s Disease in the Netherlands in 2017–2022, published in The Lancet Regional Health – Europe. He breaks down the study’s innovative methodology, which used multiple national data sources to map new Parkinson’s cases across the Netherlands, and highlights the key findings, including stable incidence over the study period,

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30:58

EP 17 – Article Of The Week: Incidence and Spatial...

Parkinson Weekly ·

2026/01/22

🎙️ We zijn terug met de zeventiende aflevering van Parkinson Weekly, gepresenteerd door prof. Bas Bloem. Bas bespreekt het Artikel van de Week: Incidence and Spatial Variation of Parkinson’s Disease in the Netherlands in 2017–2022, gepubliceerd in The Lancet Regional Health – Europe. Hij licht de innovatieve methodologie van het onderzoek toe, waarbij meerdere nationale databronnen zijn gebruikt om nieuwe gevallen van de ziekte van Parkinson in Nederland in kaart te brengen. Daarnaast

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10:01

EP 16 – Article Of The Week: Mucuna pruriens in...

Parkinson Weekly ·

2026/01/08

🎙️ We’re back with the sixteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas discusses the Article of the Week: Mucuna pruriens in untreated Parkinson’s disease in sub-Saharan Africa: A 12-month, multicenter, randomized, controlled trial. He explores the study’s design, key findings, and what this important research tells us about alternative, accessible treatment options for Parkinson’s disease, particularly in under-resourced settings, as well as its

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5:52

Bonus Episode - Christmas Special

Parkinson Weekly ·

2025/12/25

🎄🎙️ We’re back with a special Christmas bonus episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this festive episode, Bas reflects on the many developments, conversations, and lessons from 2025, offering a thoughtful and wide-ranging look at where Parkinson’s disease research and care stand today. From scientific progress and clinical practice to people, policy, and purpose, he shares his perspective on what has changed — and what still needs to evolve. Bas also looks ahead to the

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18:20

EP 15 - Adaptive Deep Brain Stimulation (aDBS) with...

Parkinson Weekly ·

2025/12/18

🎙️ We’re back with the fifteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas explores the next generation of neuromodulation with a focus on Adaptive Deep Brain Stimulation (aDBS), joined by special guest Dr. Martijn Beudel. Together, they unpack how aDBS moves beyond traditional continuous stimulation by dynamically responding to a patient’s brain signals in real time. The discussion highlights the potential of this personalised approach to improve

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7:05

EP 14 - Artificial intelligence — Great Promises &...

Parkinson Weekly ·

2025/12/11

🎙️ We’re back with the fourteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas delves into the rapidly evolving world of artificial intelligence and its growing influence on Parkinson’s disease care and healthcare in general. He explores how AI-driven tools offer remarkable new possibilities — from earlier diagnosis to personalised treatment strategies — while also highlighting the ethical, clinical, and practical concerns that come with relying on

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8:00

EP 13 - Article Of The Week: Shades Of Grey: The...

Parkinson Weekly ·

2025/12/04

🎙️ We’re back with the thirteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas explores the powerful intersection between art and Parkinson’s disease — how creativity, expression, and the artistic process can offer unique insights into living with the condition. From movement and emotion to identity and resilience, Bas reflects on the ways art can illuminate aspects of Parkinson’s that clinical measures often overlook. The article of the week, “Shades

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6:15

EP 12 – Will clinical study assessments stand the...

Parkinson Weekly ·

2025/11/27

🎙️ We’re back with the twelfth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas examines whether today’s clinical study assessments are truly prepared for the future of Parkinson’s research and care. With rapid advances in technology, emerging biomarkers, and new digital tools, long-established rating scales and outcome measures are increasingly being questioned. Do they genuinely reflect what matters most to people living with Parkinson’s? And how might

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15:01

EP 11 - Fecal Microbiota Transplantation for...

Parkinson Weekly ·

2025/11/20

🎙️ We’re back with the eleventh episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week delves into the emerging role of faecal microbiota transplantation (FMT) as a potential treatment for Parkinson’s disease. Building on growing evidence linking gut health and neurological function, the study examines whether restoring a healthy gut microbiome could help alleviate symptoms and possibly influence disease progression. 👉 You can read the full article below:

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