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PODCAST

Core IM | Internal Medicine Podcast

Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges

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All Episodes

36:50

#192 Debate on First-Line Medications for Diabetes

Core IM | Internal Medicine Podcast ·

2025/11/05

SGLT-2i vs. GLP-1? vs Metformin? How do you balance the cost and coverage of first-line options like metformin, SGLT-2, and GLP-1s? How do you choose between SGLT-2 and GLP-1s for comorbidities like CAD or CKD? And how do you weigh their side effects and practical use?🔹 Sponsor:Use the code "CORE30" for 30% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript and Show NotesTimestamps:(01:42) | Starting Treatment for Newly Diagnosed Type 2 Diabetes(08:40) | Balancing Cost, Coverage, and

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31:35

#191 Hepatorenal Syndrome Part 2 on Management: 5...

Core IM | Internal Medicine Podcast ·

2025/10/22

What really works when treating HRS? Vasoconstrictors like terlipressin vs. norepinephrine vs. midodrine: how do we decide which to use? Do you give albumin? When do you give Lasix or another diuretic? When is the better choice transplant, dialysis, or even palliative care?🔹 Sponsor: Oakstone CMEUse the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript & Show NotesTimestamps: (00:12) | Introduction and Overview of Hepatorenal Treatment (03:38) |

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36:11

#190: Hepatorenal Syndrome Part 1: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/10/15

HRS-AKI vs. other causes of AKI in cirrhosis: What do serum or urine sodium clues, albumin challenges, and shifting diagnostic criteria actually reveal about getting the diagnosis right?🔹 Sponsor: Oakstone CMEUse the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript & Show NotesTimestamps: (00:57) | Understanding the Pathophysiology of HRS (03:42) | How Portal Hypertension Traps the Kidneys (10:32) | Sorting the Differential of AKI in Cirrhosis Beyond

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30:50

#189 Bisphosphonates and Fracture Prevention Trial:...

Core IM | Internal Medicine Podcast ·

2025/10/01

Who’s really at risk for fractures, and how should we be treating them? Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions (spread years apart) of zoledronate prevent fractures for years? Have the concerns about bisphosphonates been overblown?Find out all the nuances on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.🔹 Sponsor: Oakstone CMEUse the code

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35:35

#188 Orthostatic Hypotension Part 2: Gray Matters...

Core IM | Internal Medicine Podcast ·

2025/09/22

Medications for orthostatic hypotension! When to initiate treatment, how to use them safely, and what to do when new issues arise during treatment. How do those change if someone has autonomic failure? What do you do when your patient has hypertension AND also has orthostatic hypotension?🔹 Sponsor: Oakstone CME’Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript & Show Notes Timestamps (+/- 1-2 mins):(00:28) | Case Recap: Beyond Non-Pharm

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37:20

#187 Orthostatic Hypotension Part 1: Gray Matters...

Core IM | Internal Medicine Podcast ·

2025/09/11

Learn specific, practical ways to counsel patients on non-pharmacologic interventions. What is our goal with OH treatment? Is it the blood pressure number that matters? How do we avoid missing neurogenic causes of orthostatic hypotension (OH)? 🔹 Sponsor: Oakstone CME’Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript & Show NotesTimestamps:(00:05) | Case Presentation: Urinary Retention → Lightheadedness(02:37) | Defining Orthostatic Hypotension &

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37:03

#186 Pneumothorax: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/08/25

Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks!🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio CompanionUse the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript & Show NotesTimestamps:(02:50) | Xray vs. POCUS vs. CT for Pneumothorax Diagnosis(07:29) | Do All PTXs Need Chest Tubes?(11:55) | Explaining Pneumothorax to Patients(14:58) | Understanding the Pleural

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42:21

#185 Neutropenia: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/08/13

How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only Pseudomonas coverage? When do you add fungal coverage?🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio CompanionUse the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript & Show Notes Timestamps:(02:24) | Approach to Neutropenia &

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10:44

#184 Stories for the Feels

Core IM | Internal Medicine Podcast ·

2025/07/28

Have a good laugh and reflect deeply with these three stories that hit the feels in different ways.If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast: July Stories and Handoffs & Contingency Planning.🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio CompanionUse the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript and Show NotesTimestamps:(01:04) | Story 1: Sharing a Personal Story for Patient

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33:11

#183 Diagnose the Clinician: Hoofbeats Segment

Core IM | Internal Medicine Podcast ·

2025/07/21

What went wrong? What were the reasoning or contextual missteps that led us astray?🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025🔹 Transcript and Show NotesTimestamps:(00:02) | Case Presentation and Initial Diagnosis(02:47) | Tachycardia and Early Impressions(04:10) | Clinical Deterioration and New Clues(07:19) | Problem Representation and Reflection(21:45) | Lessons on Reasoning and Bias(26:55) | Final Takeaways and Action StepsTags: Clinical Reasoning,

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36:15

#182 Pleural Effusions: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/07/09

Imaging Pearls | (01:12) Deciding on Thoracentesis | (04:00)Light’s Criteria and Pseudoexudates | (07:00)Pleural Fluid Studies: pH and Cell Differential | (16:56) Diagnosing and Treating Parapneumonic Effusions | (23:32)Malignant Pleural Effusions: Diagnosis and Management | (30:39)🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio CompanionUse the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP🔹 Transcript and Show NotesTags: Internal Medicine, Medical Education, Pulmonology,

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15:58

#181 July Stories 3.0

Core IM | Internal Medicine Podcast ·

2025/07/02

What happens when your first day as an intern spirals into your worst fears?In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine.🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025🔹 Transcript and Show NotesPrior July Stories:July Stories 2.0 (2023)July Stories (2019)Timestamps:(00:32) | Dr. Ali Trainor's First Day as an Intern(03:00) | The

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26:41

#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal...

Core IM | Internal Medicine Podcast ·

2025/06/25

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions whether beta blockers are still needed for all.Listen to this latest episode of Beyond Journal Club, a collaboration between Core IM and NEJM Group, where we put research into context tracing the arc of evidence, dissecting the clinical question, and exploring

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45:02

#179 Invasive Fungal Disease: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/06/11

🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46)🔹 What are the main classes of fungi? (~11:35)🔹 What are the pros and cons of B-D Glucan and Galactomannan (~19:16) 🔹 How to increase the yield of blood cultures? How to interpret yeast growth in sputum/BAL and urine cultures? (~ 30:42)🔹 How is invasive fungal disease treated? (~ 35:14)📌 Sponsor: Oakstone CME’s ACP MKSAP Audio CompanionUse the code "CORE25" for 25% off:

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33:34

#178 Continuous Glucose Monitor (CGM): 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/06/02

🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40)🔹What do the different parts of the ambulatory glucose profile tell you? (09:59)🔹What are common pitfalls, medications, lifestyle patterns that are important to ask your patient about when seeing them for a visit to manage blood sugar? (15:19)🔹 How can you titrate insulin based on when you see the hypoglycemia on the ambulatory glucose profile (20:00)🔹 When there is too much hyperglycemia, how do you titrate insulin when adding

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43:53

#177 Interventional Radiology (IR) 101: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/05/14

🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology?🔹What factors go into an IR pre-op evaluation?🔹 When do drains go in, and when do they come out?🔹 When a patient has trouble with a drain, what are things you can do before calling IR?🔹 What does outpatient IR follow up entail, and what does a capping trial of PCN tubes entail?📌 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion Use the code "CORE25" for 25% off:

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39:43

#176 Constipation Medications: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/04/30

🔹 High-yield reversible causes of constipation? (02:26)🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03)🔹 Osmotic vs Stimulant Laxatives (15:06)🔹 Suppositories and enemas? (25:39)🔹Best practices with opioid induced constipation (34:05)📌 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! Use the code CORE50 to get 50% off your first month

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27:44

#175 A Revolution in HIV Prevention & The PURPOSE...

Core IM | Internal Medicine Podcast ·

2025/04/16

How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP — a potential game-changer in the field of HIV.Listen to this latest episode of Beyond Journal Club, a collaboration between CoreIM and NEJM Group, where we put research into context, telling the story of how we arrived at the current standard of care,

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43:20

#174 Lp(a) and ASCVD Risk: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/04/02

What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment.🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! Use the code CORE50 to

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44:49

#173 Hypercoagulability Workup: 5 Pearls Segment

Core IM | Internal Medicine Podcast ·

2025/03/19

A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! Use the code CORE50 to get 50% off your first month with Freed🔹 This episode is also sponsored by Factor! Get fresh,

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