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PODCAST

Mayo Clinic Talks

Timely consultations relevant for family medicine, primary care, and general internal medicine topics for physicians, nurse practitioners, physician assistants, and residents. Offering CME credit for most episodes at https://ce.mayo.edu/podcast. Produced by @MayoMedEd.

education medicine

All Episodes

33:34

Mayo Clinic Proceedings: Diabetes and Novel Therapies...

Mayo Clinic Talks ·

2026/04/09

Host: Darryl S. Chutka, M.D. Guest: Vinaya Simha, M.B.B.S., M.D. For years, we saw very little change in the management of type 2 diabetes. However, over the past decade, numerous new pharmacologic treatment options, innovations in glucose monitoring, and new insulin delivery systems have become available. We’ve also seen a new philosophy regarding the goals of diabetes management. What are the latest medications for diabetes and is there still a role for the older, traditional options? How have

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28:30

Mayo Clinic Proceedings: Healthy Aging

Mayo Clinic Talks ·

2026/04/07

Host: Darryl S. Chutka, M.D. Guest: Robert Pignolo, M.D., Ph.D. Our population is aging as our life expectancy increases with time. In general, we’re living longer than those before us. Aging is an interesting concept; we all want to achieve old age, but it’s not something we look forward to. What we really want is to maintain our physical, mental and social well-being in order to achieve a high quality of life as we age. I’m talking about healthy aging and that’s the topic of this podcast. What

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31:38

Mayo Clinic Proceedings: Sleep Disorders and How They...

Mayo Clinic Talks ·

2026/04/02

Host: Darryl S. Chutka, M.D. Guest: Bhanu Kolla, M.D. We commonly take sleep for granted. That is, until our sleep quantity or quality is compromised. This can result in both mental and physical health problems, including daytime fatigue and sleepiness. Sleep disorders are quite common and often undiagnosed, yet they can contribute to diabetes, cognitive impairment, and cardiovascular disease, potentially leading to premature mortality. Primary care clinicians play a major role in the

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32:35

Retinal Disorders

Mayo Clinic Talks ·

2026/03/31

Host: Darryl S. Chutka, M.D. Guest: Brittni A. Scruggs, M.D., Ph.D. There are a variety of eye disorders which involve the retina, and they all have the potential to cause significant vision loss or blindness if not detected early. Two of the most common retinal disorders we see in primary care include diabetic retinopathy and macular degeneration. Since most health conditions affecting the retina are asymptomatic early in their course making patient screening and risk factor management an

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28:50

Update in the Management of Hyperlipidemia

Mayo Clinic Talks ·

2026/03/24

Host: Darryl S. Chutka, M.D. Guest: Stephen Kopecky, M.D. Cardiovascular disease is highly prevalent in our society. Fortunately, we have a variety of treatment options to lower the risk of developing its complications. Over the past decade, there’ve been many changes in managing hyperlipidemia, one of the most important risk factors for cardiovascular disease. This includes a change in assessing our patients’ risk, identification of new risk factors, new testing options, and new pharmacologic

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24:25

Pulmonary Vascular Complications of Liver Disease

Mayo Clinic Talks ·

2026/03/17

Host: Darryl S. Chutka, M.D. Guest: Kathryn del Valle, M.D. Chronic liver disease can result in a variety of complications which can involve multiple organs. One of these complications can occur in the pulmonary vascular system. Two of the most clinically significant include hepatopulmonary syndrome and Portopulmonary hypertension. Patients with these syndromes may present to their primary care provider and if the medical condition is unrecognized, it can affect morbidity and ultimately

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20:20

Non-Hodgkin's Lymphoma

Mayo Clinic Talks ·

2026/03/12

Host: Darryl S. Chutka, M.D. Guest: Stephen Ansell, M.D., Ph.D. Non-Hodgkin’s Lymphoma is a group of hematologic malignancies originating in the lymphatic system. There are over 60 subtypes of lymphoma with varying degrees of aggressiveness. It can present with a variety of rather subtle symptoms, often making the diagnosis challenging. Although Non-Hodgkin’s Lymphoma is typically managed by a hematologist or oncologist, the primary care provider plays a role in its recognition, preliminary

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24:39

Hodgkin's Lymphoma

Mayo Clinic Talks ·

2026/03/10

Host: Darryl S. Chutka, M.D. Guest: Stephen Ansell, M.D., Ph.D. Hodgkin’s Lymphoma is an uncommon but very curable malignancy involving the lymphatic system. It most commonly presents in young adults as well as middle-aged and older individuals. Although Hodgkin’s is generally managed by hematologists or oncologists, the primary care provider plays a major role in its recognition, hopefully leading to a timely diagnosis and eventual staging. What are some early signs of Hodgkin’s and what

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29:57

Heart Health Series | Diastolic Heart Failure

Mayo Clinic Talks ·

2026/03/03

Host: Darryl S. Chutka, M.D. Guests: Jae K. Oh, M.D., Tahir S. Kafil, M.D. Diastolic heart failure is also known as heart failure with preserved ejection fraction. Although we don’t hear the term all that often, it actually represents a fairly large percentage of all cases of heart failure. Some studies suggest it represents the majority of heart failure cases. Older adults are most commonly affected with symptoms similar to those of systolic heart failure. So how do we suspect diastolic heart

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26:11

Heart Health Series | Cardiotoxicity of Cancer Therapies

Mayo Clinic Talks ·

2026/02/24

Host: Darryl S. Chutka, M.D. Guest: Balaji Tamarappoo, M.D., Ph.D. With advances in oncology, patients are living longer than ever following a diagnosis of cancer. Newer treatments have dramatically improved survival. However, we’re also seeing an increasing number of cancer survivors who are at risk for cardiovascular complications; at times during treatment, and sometimes years later. Complications such as heart failure, cardiac arrhythmias, hypertension, and accelerated coronary disease

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28:01

Heart Health Series | Pericardial Disease

Mayo Clinic Talks ·

2026/02/17

Host: Darryl S. Chutka, M.D. Guest: Hema Narayanasamy, M.B.B.S. Pericardial disease represents a spectrum of both inflammatory and non-inflammatory disorders which involve the pericardium, with acute pericarditis being the most common disorder. Although not often seen in a primary care practice, we still need to consider pericarditis as it can masquerade several other more commonly seen conditions. It’s important to recognize pericardial disease early and decide who needs an urgent referral or

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20:03

The Power of Intervals: High Intensity Interval...

Mayo Clinic Talks ·

2026/02/10

Host: Darryl S. Chutka, M.D. Guest: Stephen Kopecky, M.D. We have a variety of pharmacologic options and lifestyle changes we recommend to our patients to reduce their cardiovascular risks. One frequent recommendation is participation in a regular exercise program. One specific type of exercise is high intensity interval training. It’s been shown to improve a variety of metabolic parameters. What does high intensity interval training consist of? What are the specific metabolic benefits? Can all

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29:23

Heart Health Series | Bicuspid Aortic Valve Disease

Mayo Clinic Talks ·

2026/02/05

Host: Darryl S. Chutka, M.D. Guest: George Wang, M.D. Bicuspid aortic valve is a relatively common congenital heart disease. It can be associated with other genetic disorders such as Turner’s Syndrome or exist as an isolated entity. In most cases, patients with a bicuspid aortic valve are initially asymptomatic; however later in the course, they may develop symptoms related to a subsequent aortic stenosis or regurgitation. It’s also associated with a dilated ascending aorta with potential rupture

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29:35

Heart Health Series | Cardiac Amyloidosis

Mayo Clinic Talks ·

2026/02/03

Host: Darryl S. Chutka, M.D. Guest: Julie Rosenthal, M.D. Cardiac amyloidosis is not a common condition, but it is important for primary care clinicians to recognize it in our patients. It’s commonly underdiagnosed as the symptoms are often assumed to be due to other, more common cardiac problems. Early recognition is important since this can result in improved treatment options and better patient outcomes. So how do we recognize cardiac amyloidosis? What are the presenting symptoms and what’s the

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27:36

Concussions: What Every Primary Care Provider Should...

Mayo Clinic Talks ·

2026/01/27

Host: Darryl S. Chutka, M.D.Guest: Matthew B. Anastasi, M.D. Patients with concussions are commonly seen in primary care practices and concussions don’t spare any particular age group. Children, young adult athletes and older individuals are all at increased risk. They’re a form of traumatic brain injury and while most are self-limiting, they require an accurate assessment, proper management and appropriate follow-up to make sure the patient is recovering and not experiencing complications. When

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26:17

Rx for Weight Loss: A Closer Look Series "The Wins of...

Mayo Clinic Talks ·

2026/01/20

Host: Darryl S. Chutka, M.D. Guest: Stephen Kopecky, M.D. One of the biggest surprises we’ve seen in medicine in the past several years has been the numerous health benefits realized from the GLP-1 agonists. Originally developed for the management of diabetes, they’ve shown significant potential to improve cardiovascular risks, beyond controlling blood glucose and lowering hemoglobin A1c. Several studies have shown reductions in cardiovascular events including MI, stroke as well as reducing

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24:22

Rx for Weight Loss: A Closer Look Series...

Mayo Clinic Talks ·

2026/01/15

Host: Darryl S. Chutka, M.D. Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B. The class of medications known as the GLP-1 agonists is very popular with our patients. Although initially indicated for management of diabetes, they’re frequently taken for the weight loss they commonly produce. How long should these medications be taken? Is there anything we can do to help maintain the weight loss achieved with these medications? How significant is the loss of muscle mass which can occur

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26:02

Rx for Weight Loss: A Closer Look Series "Importance...

Mayo Clinic Talks ·

2026/01/13

Host: Darryl S. Chutka, M.D. Guest: Tamim Rajjo, M.D., M.P.H. Using GLP-1 medication for weight loss has become very popular with our patients. In the recent past, this has produced a shortage of these medications available, and those taking them for management of diabetes have found them difficult to obtain. Although in most cases, they are quite successful in producing substantial weight loss, many have regained weight after the medication was discontinued. How much weight can patients expect to

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26:17

Rx for Weight Loss: A Closer Look Series “Who is a...

Mayo Clinic Talks ·

2026/01/08

Host: Darryl S. Chutka, M.D.Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B. Using GLP-1 medications for weight loss has become extremely popular. Is this the latest fad in losing weight, or will these medications completely change our approach to managing obesity? They do appear to be very effective in promoting substantial weight loss. What is the history of these medications? Are there differences in the various GLP-1 medications available? What are the potential adverse effects of

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23:34

The Risks and Benefits of Alcohol

Mayo Clinic Talks ·

2026/01/06

WELCOME TO SEASON 6 OF THE MAYO CLINIC TALKS PODCAST! Host: Darryl S. Chutka, M.D. Guest: Warren G. Thompson, M.D. Alcohol can offer a variety of social and potential health benefits when consumed in moderation. However, alcohol is also associated with a variety of health risks, including addiction, increased likelihood of accidents, impaired judgment, cardiovascular problems, hepatic disease and even malignancy. Other than the social benefits, are there true health benefits of alcohol? Is there an

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