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PODCAST

Oxford Sparks Big Questions

"Will my bacon sandwich kill me?", "Is vaping better than smoking?", "How do you become an astronaut?" - just some of the Big Questions we ask some of the brightest minds behind Oxford science. Join us in each podcast as we explore a different area of science.

science natural sciences

All Episodes

12:15

How do you find a theoretical particle?

Oxford Sparks Big Questions ·

2025/08/06

How do you detect a particle that emits no light - in other words, something invisible? This is the intriguing challenge faced by scientists hunting for 'dark matter'. In our series finale, we talk to Elizabeth Bloomfield from Oxford's Department of Physics about dark matter, how we know it exists, and why her research is taking her deep beneath a mountain in Italy in the quest to find it.

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14:52

Is there a better way to screen blood?

Oxford Sparks Big Questions ·

2025/06/25

What's the best gift you can give? To the millions of people whose lives have been saved by complete strangers, the answer would be simple: blood. But what exactly happens when blood has been donated, and how do we know it is safe? We chat to Dr Richard Mayne from Oxford's Experimental Medicine Division about genomics, Next-Generation Sequencing, blood screening (...and Star Trek). Could you be a blood-donating hero? Blood stocks are currently critically low, with the NHS Blood and Transplant

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13:20

How does Ozempic actually work?

Oxford Sparks Big Questions ·

2025/06/11

Whether you've been served an advert for it, or just heard about it in the media, it's likely that 'Ozempic' isn't a totally unfamiliar word. Now often associated with weight-loss, Ozempic is actually the brand name for a drug used to treat diabetes. So what exactly is it, how does it work, and is it safe? We chat to diabetes and endocrinology (hormone) expert Dr Annie de Bray to find out.

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16:39

Why does a stranger's phone noise annoy me?

Oxford Sparks Big Questions ·

2025/05/28

We've all been there...you're on the train, maybe tired after a long day, and all you can hear is one side of a fellow passenger's not-too-interesting phone conversation. Or worse, their choice of music, made tinny and monotonous by the awkward angle of their phone speaker. It's irritating, sure, but for some people it goes beyond mild annoyance, into the realms of anger and panic. For these people - who suffer from a condition called 'misophonia' - phone noise, or sounds such as chewing or

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14:31

What's the origin of water on Earth?

Oxford Sparks Big Questions ·

2025/05/14

With more than 70% of its surface covered in water, Earth is rightly known as the "blue planet". But where did this water - so essential to life - originate? While some theories suggest that hydrogen was delivered to Earth from space via asteroids, new research indicates that the building blocks for water may have been present on our planet all along. We chat to Tom Barrett from Oxford's Department of Earth Sciences to find out more.

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13:56

How can robots investigate underwater volcanoes?

Oxford Sparks Big Questions ·

2025/04/30

What do you do when the subject of your research lies deep beneath the waves? Send down an underwater robot, of course! We chat to volcanologist Sofia Della Sala about her recent fieldwork expedition to Santorini, where she used a Remotely Operated Vehicle, or ROV, to search for hydrothermal vents in the Aegean Sea. These vents - which are like hot springs on the sea floor - could provide vital insight into the volcanic and tectonic activity in the region.

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15:57

What is it like to be on Countdown?

Oxford Sparks Big Questions ·

2025/04/16

"I still don't believe it happened..." What's it like to face the most famous clock on television? We chat to Oxford mathematician Dr Tom Crawford - best known as the creator of the award-winning 'Tom Rocks Maths' outreach programme - about what it was like to step into Rachel Riley's shoes on Countdown. What's the best tactic for tackling the numbers round? How did he prepare? Did he really only have 30 seconds to find a solution? Tom gives us a glimpse behind-the-scenes of this British

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14:35

What happens after a dementia diagnosis?

Oxford Sparks Big Questions ·

2025/04/02

One in two people will be affected by dementia in their lifetime - whether that is as a patient, or somebody caring for a loved one. But what happens after a dementia diagnosis? Is there a clear pathway ahead? We chat to Jasmine Blane, a DPhil researcher at the Oxford Brain Health Clinic, about the work she is doing to help support patients in the midst of a dementia diagnosis, and into the future.

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15:20

Is it OK to laugh at Tourette's?

Oxford Sparks Big Questions ·

2025/03/19

In popular culture, Tourette's syndrome is wrongly associated solely with outbursts of swearing in the context of lazy jokes. But in reality, the condition is far more complex than this stereotype suggests. When people without Tourette’s jokingly blame their lack of self-control on the condition, it spreads misinformation and invalidates those who actually live with it. Despite this, comedy - when created by those who experience stigma - can sometimes help challenge stereotypes and shift public

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13:57

What is a dinosaur highway?

Oxford Sparks Big Questions ·

2025/03/05

If you were hunting for some fossilised dinosaur footprints, where would you go? To a remote part of North or South America, perhaps? A deserted wilderness for sure... But how about Oxfordshire? We chat to Dr Duncan Murdock from the Oxford University Museum of Natural History about an incredible discovery made right on our doorstep. Photo © Dr Emma Nicholls / Oxford University Museum of Natural History

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15:20

How horny are hedgehogs?

Oxford Sparks Big Questions ·

2025/02/19

Shh...hedgehog! It always feels like a privilege to catch a glimpse of one, as it snuffles away under the garden fence. And come the spring, our spiny - and usually solitary - little friends will be feeling in the mood for...romance. But what exactly does a female look for in a mate? And how do their intimate encounters even work when things are so very... spiky? Join us for this special Valentine's Day edition of the Big Questions Podcast, as we ask Dr Sophie Lund Rasmussen (aka Dr Hedgehog) "how

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12:00

What can batteries of the future learn from eels?

Oxford Sparks Big Questions ·

2025/02/05

Electric eels are pretty amazing creatures. Their bodies can release powerful electric charges - in some cases reaching 650 volts! So, what can scientists learn from these animals? Could nature hold the key to advancing our own energy solutions? We chat to Dr Yujia Zhang about how electric eels might inspire the batteries of the future.

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11:17

Why is my bottle cap attached to my plastic bottle?

Oxford Sparks Big Questions ·

2025/01/22

Whether it's the bottle of water that you hastily grab at the train station, or your favourite guilty-pleasure fizzy pop, you may have noticed something different about your drinks lately - or at least their containers. Since July 2024, it's been EU law that bottle caps are attached, or 'tethered', on all single-use plastic bottles. But what exactly is the reason for this change? Will it really help to save the planet, or is it just there to annoy us? We chat to Dr Diogo Veríssimo about "nudge",

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13:19

Why are we seeing the Northern Lights more often?

Oxford Sparks Big Questions ·

2025/01/08

Even if you’d never previously given much thought to the Northern Lights, chances are they were brought to your attention in 2024, when our social media feeds were set ablaze with beautiful images captured by awe-struck stargazers. Usually restricted to more northerly latitudes, this colourful natural phenomenon could be observed in the UK as far south as Cornwall. But why were we treated to this spectacle, and why now? Dr Carly Howett from the Department of Physics explains why we’re seeing the

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13:40

Why track mistletoe?

Oxford Sparks Big Questions ·

2024/12/11

Mistletoe has long been associated with fertility, and even today, its presence hanging from the ceiling can prompt a few blushes. But, did you know, mistletoe is more than something beneath which to kiss at Christmas? It is actually a parasite, and has some rather peculiar biology behind it. We chat to mistletoe expert Ollie Spacey about what makes it so special, where you can spot it and - importantly - how you can get involved with his research through MistleGO!

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12:35

Why are birth rates falling in the UK?

Oxford Sparks Big Questions ·

2024/11/27

Evolutionarily speaking, it makes sense to have a lot of children. At the very least, we might expect a population to replace itself, with each couple having an average of two children. However, this evolutionary logic is not mirrored by current data: birth rates are falling in the UK, with many people choosing to either have one child, or no children at all. We speak to evolutionary anthropologist Dr Paula Sheppard about the drivers, and consequences, of this observed trend.

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12:55

What is a wind drought?

Oxford Sparks Big Questions ·

2024/11/13

Chances are, you didn't notice the week-long wind drought that the UK experienced towards the end of 2023. However, this period of low wind speeds, combined with a cold snap, drove up our energy prices - something that may have caught your attention. So, what exactly do we know about wind droughts, and how can we apply this knowledge to plan for the low-carbon energy systems of the future? We chat to Matthew Wright from Oxford's Department of Physics to find out.

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14:05

How do you sequence the genomes of 70,000 species?

Oxford Sparks Big Questions ·

2024/10/30

Welcome back to the new series of the Oxford Sparks Big Questions Podcast! We are here to answer weird and wonderful questions about our world, with the help of science. And we’re starting with a very big question! How do you sequence the genomes of 70,000 species? Dr Liam Crowley, from the Department of Biology, tells us about the ground-breaking Darwin Tree of Life project, which aims to sequence the genomes of over 70,000 species in Britain and Ireland. Discover the challenges and technological

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13:52

How do I keep my house cool without air conditioning?

Oxford Sparks Big Questions ·

2024/07/17

Summer is here, and with heatwaves forecast, how do we keep our homes cool without relying on air conditioning? In the UK, soaring summer temperatures can be brief but powerful. So, what can we do? Nicole Miranda, from the Department of Engineering, shares practical, energy-efficient and eco-friendly strategies to help you stay comfortable during the hot months. And yes, ice creams are encouraged! This is the final episode of this season. We hope that you have enjoyed learning the science behind

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14:45

What time is it on the moon?

Oxford Sparks Big Questions ·

2024/07/03

Scientists are returning to the moon, but when they get there, what time is it? Dr Carly Howett from the Department of Physics explains the basics: what time is, and how we found a globalised way of understanding time zones so we can meet for a 3pm coffee or international video call, and everyone is in the right place at the right time. But how does that translate to space and why could the consequences of incorrect timekeeping be disastrous for space craft docking missions? If you want to get to

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