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PODCAST

AI + a16z

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.

technology entrepreneurship

All Episodes

00:39:25

Building the “See Something, Say Something” AI for...

AI + a16z ·

2025/12/16

a16z's Martin Casado sits down with Shikhar Shrestha, CEO and cofounder of Ambient, the company bringing agentic AI to physical security.Shikhar shares how a traumatic armed robbery at age 12—and a security camera that no one was watching—sparked his mission to make every camera intelligent.They discuss how Ambient's AI monitors camera feeds in real-time to detect threats and prevent incidents before they happen, navigating COVID as a physical security company, building their own reasoning VLM

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00:39:12

The AI That Found A Bug In The World’s Most Audited Code

AI + a16z ·

2025/12/10

Matt Knight spent five years as OpenAI’s CISO. Now he runs what colleagues call “the most interesting job at the company”: leading Aardvark, an AI agent that finds security vulnerabilities the way a human researcher would—by reading code, writing tests, and proposing patches. It recently found a memory corruption bug in OpenSSH, one of the most heavily audited codebases in existence.In this conversation with a16z’s Joel de la Garza, Matt traces the evolution from GPT-3 (which couldn’t analyze

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01:22:53

The Death of Data Gatekeeping: AI Makes Everyone An...

AI + a16z ·

2025/12/05

Most companies still rely on dashboards to understand their data, even though AI now offers new ways to ask questions and explore information. Barry McCardel, CEO of Hex and former engineer at Palantir, joins a16z General Partner Sarah Wang to discuss how agent workflows, conversational interfaces, and context-aware models are reshaping analysis. Barry also explains how Hex aims to make everyone a data person by unifying analysis and AI in one workflow, and he reflects on his post about getting rid

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00:25:14

Why Social Engineering Now Works on Machines

AI + a16z ·

2025/12/02

Ian Webster built PromptFoo after watching 200 million Discord users systematically dismantle his AI agent—now Fortune 10 companies pay him to break theirs before customers do. The "lethal trifecta" sounds academic until you realize it's already happening: untrusted input plus sensitive data plus an exfiltration channel equals the security incident that just cost a SaaS company its multi-tenancy guarantees. Webster's red-teaming agents don't use signatures—they have 30,000 conversations with your

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00:57:59

“Anyone Can Code Now” - Netlify CEO Talks AI Agents

AI + a16z ·

2025/11/28

Netlify's CEO, Matt Biilmann, reveals a seismic shift nobody saw coming: 16,000 daily signups—five times last year's rate—and 96% aren't coming from AI coding tools. They're everyday people accidentally building React apps through ChatGPT, then discovering they need somewhere to deploy them. The addressable market for developer tools just exploded from 17 million JavaScript developers to 3 billion spreadsheet users, but only if your product speaks fluent AI—which is why Netlify's founder now submits

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00:46:35

From Code Search to AI Agents: Inside Sourcegraph's...

AI + a16z ·

2025/11/25

Sourcegraph's CTO just revealed why 90% of his code now comes from agents—and why the Chinese models powering America's AI future should terrify Washington. While Silicon Valley obsesses over AGI apocalypse scenarios, Beyang Liu's team discovered something darker: every competitive open-source coding model they tested traces back to Chinese labs, and US companies have gone silent after releasing Llama 3. The regulatory fear that killed American open-source development isn't hypothetical anymore—it's

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00:52:01

Ryo Lu (Cursor): AI Turns Designers to Developers

AI + a16z ·

2025/11/21

Ryo Lu spent years watching his designs die in meetings. Then he discovered the tool that lets designers ship code at the speed of thought: Cursor, the company where Ryo is now Head of Design. In this episode, we discuss why "taste" is the wrong framework for understanding the future, why purposeful apps are "selfish," how System 7 holds secrets about AI interfaces, and the radical bet that one codebase can serve everyone if you design the concepts right instead of the buttons.Follow Ryo Lu on X:

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00:57:06

How Foundation Models Evolved: A PhD Journey Through...

AI + a16z ·

2025/11/18

The Stanford PhD who built DSPy thought he was just creating better prompts—until he realized he'd accidentally invented a new paradigm that makes LLMs actually programmable. While everyone obsesses over whether LLMs will get us to AGI, Omar Khattab is solving a more urgent problem: the gap between what you want AI to do and your ability to tell it, the absence of a real programming language for intent. He argues the entire field has been approaching this backwards, treating natural language prompts

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00:28:37

TruffleHog Creator: You Can’t Have AI Agents Without...

AI + a16z ·

2025/11/11

If you can’t robustly protect your secrets, you can’t have reliable AI agents.In this episode, Truffle Security cofounder and CEO Dylan Ayrey joins a16z partner Joel de la Garza to discuss the emergent security stack for AI agents, why leaks are actually getting worse, and how Truffle evolved from an open-source side project to a major VC-backed startup. Follow Dylan here: https://x.com/InsecureNatureFollow Joel here: https://www.linkedin.com/in/3448827723723234/Check out everything a16z is doing

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00:38:43

Tigris Data CEO on Building Your Own Datacenters

AI + a16z ·

2025/11/07

In this episode, a16z General Partner Martin Casado sits down with Ovais Tariq, Cofounder and CEO of Tigris Data, to discuss why independent storage is so hard, what operating your own datacenters is like, and what’s in store for the future of cloud.ResourcesFollow Ovais on X: https://x.com/ovaistariqFollow Tigris Data on X: https://x.com/tigrisdataFollow Martin on X: https://x.com/martin_casadoCheck out everything a16z is doing with artificial intelligence here, including articles, projects, and

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00:47:31

Pylon: Reimagining B2B Customer Support

AI + a16z ·

2025/10/31

Customer support platforms lacked adequate solutions for B2B companies - until Pylon entered the scene.We sat down with Pylon cofounders Marty Kausas, Advith Chelikani, and Robert Eng to discuss why they went into B2B, how they plan to beat huge competitors, and why they still live together in a windowless apartment and work 9-9-6 hours despite having raised tens of millions.Follow Pylon on X: https://x.com/usepylonFollow Marty on X: https://x.com/marty_kausasFollow Advith on X:

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00:32:41

Keycard: 2026 is the Year of Agents

AI + a16z ·

2025/10/22

In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycard to manage fleets of agents.In this conversation, a16z Partner Joel de la Garza sits down with Keycard Cofounder and CEO Ian Livingstone to discuss the continuum from copilots to agents, the security realities of tool-calling, why enterprises will adopt before consumers, and how to control your agents. Follow Joel on LinkedIn:

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00:38:06

The Trillion Dollar AI Software Development Stack

AI + a16z ·

2025/10/10

AI coding has emerged as a major market for AI: one that’s already rewriting how software gets built.a16z Infra Partners Yoko Li and Guido Appenzeller break down how “agents with environments” are changing the dev loop; why repos and PRs may need new abstractions; and where ROI is showing up first (like legacy code migration). We also cover token economics for engineering teams, the emerging agent toolbox (sandboxes, code search/parsing, agent-optimized docs, orchestration), and founder

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00:34:26

Material Security CEO: How To Find Your Ideal Customer

AI + a16z ·

2025/10/06

What if the hardest part of building a company isn’t the product, but knowing exactly who it’s for?In this episode, a16z General Partner Martin Casado sits down with Abhishek Agrawal, Cofounder and CEO of Material Security, to discuss how an ideal customer profile is discovered, how to manage any kind of customer, and how frothy markets can distort real signal.Follow Martin on X: https://x.com/martin_casadoFollow Material Security on X: https://x.com/material_secFollow Abhishek on LinkedIn:

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00:22:11

When Deepfakes Steal $30M: The New Edge of Cybercrime

AI + a16z ·

2025/09/26

AI is transforming both sides of the cybersecurity cat-and-mouse game. Attackers are using LLMs to scale impersonation, phishing, and even deepfake fraud—while defenders are racing to automate detection and takedowns at the same speed.In this episode, a16z partner Joel de la Garza talks with Kevin Tian, cofounder & CEO of Doppel Security (and former Uber engineer), about building in this new landscape. They cover:Why outsider founders sometimes build the most effective security companiesThe “3 V’s”

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00:51:41

How AI Will Change Photography Forever

AI + a16z ·

2025/09/17

What if you could retake your favorite memories years after they happened, fixing the lighting, catching the smile, or even opening your eyes?In this conversation, a16z General Partner Martin Casado and Partner Yoko Li sit down with scientist and Lytro founder Ren Ng along with Phota Labs cofounders Cecilia Zhang and Zhihao “Zach” Xia to explore the past, present, and future of computational photography. They trace the story from the invention of light-field cameras and the evolution of smartphone

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01:19:36

How OpenAI Built Its Coding Agent

AI + a16z ·

2025/08/29

OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software?In this episode, General Partner Anjney Midha goes behind the scenes with one of Codex’s product leads- Alexander Embiricos - to unpack its origin story, why its PR success rate is so high, the safety challenges of autonomous agents, and what this all means for developers, students, and the future of coding.Resources: Find Alex

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00:47:15

Models, Modalities, and Memes: Creating Compelling AI...

AI + a16z ·

2025/08/14

Models, Modalities, and Memes: Creating Compelling AI CharactersIn this episode of AI + a16z, Hedra founder and CEO Michael Lingelbach joins a16z partners Justine Moore and Matt Bornstein to talk about building AI-native video — and why the next wave of generative content is all about characters, not just clips.They discuss how Hedra’s expressive, full-body, dialogue-centric video models are powering everything from viral meme content to enterprise training tools. Michael explains why “character” is

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00:40:10

Performance and Passion: Fal's Approach to AI Inference

AI + a16z ·

2025/08/01

If you've been experimenting with image, video, and audio models, the chances are you've been both blown away by how good they're becoming, and also a little perturbed by how long they can take to generate. If you've been using a platform like Fal, however, your experience on the latter point might be more positive.In this episode, Fal cofounder and CEO Burkay Gur and head of engineering Batuhan Taskaya join a16z general partner Jennifer Li to discuss how they built an inference platform — or, as

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00:26:35

How to Vibe Code Securely

AI + a16z ·

2025/07/25

In this episode, a16z partner Joel de la Garza sits down with Socket founder and CEO Feross Aboukhadijeh to dive into the intersection of vibe coding and security. As one of the earliest security founders to fully embrace LLMs, Feross shares firsthand insights into how these technologies are transforming software engineering workflows and productivity — and where there are sharp edges that practitioners need to avoid.The TL;DR: Treat AI-assisted programming the same way you'd treat other

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72 results

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