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PODCAST

Intelligent Medicine with Dr. Ronald Hoffman | The Best of High Tech Medicine and Alternative Modalities

Dr. Ronald Hoffman | Pioneering Complementary Medicine Practitioner

Pioneering complementary medicine practitioner Dr. Ronald Hoffman takes a cutting-edge approach to health, wellness, and aging. He covers both conventional and alternative modalities, as well as nutrition, exercise, and supplements.

health & fitness alternative health

All Episodes

35:25

Intelligent Medicine Radio for October 3, Part 1:...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/10/05

Ever more powerful weight loss drugs are on the launchpad as FDA issues warnings about bootleg versions—and potential hazards of drastic weight loss to seniors and those with eating disorders; Botched Tennessee execution—how can that happen? Immune support for respiratory syncytial virus (RSV) in a lung cancer survivor; Should beta-glucans be taken with—or away from—food for optimal absorption? Boosting bone density with an exercise program targeted for osteopenia/fall prevention.

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35:23

Intelligent Medicine Radio for October 3, Part 2: The...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/10/05

Do you have to worry about too much vitamin A from supplements? Urolithin A scores against a common form of heart failure; Most blood tests don’t require fasting; The health scourge of E-bikes; Slashing sugar before antibiotics reduces harms to microbiome; Study shows inadequate REM sleep associated with 83 diseases—but doubts persist over accuracy of sleep wearables.

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22:21

Leyla Weighs In: Time-Restricted Eating vs. Usual...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/10/02

Time-Restricted Eating Study: Nutritionist Leyla Muedin details a Johns Hopkins Medicine study (published July 27 in Obesity) on time-restricted eating (TRE), a form of intermittent fasting that limits eating to a consistent 8–10 hour daily window, in adults with obesity and prediabetes or diet-controlled type 2 diabetes. In a 12-week trial of mostly female and Black participants, groups followed either a 10-hour TRE schedule or a usual 16-hour eating pattern, while all received a provided,

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28:36

Q&A with Leyla, Part 1: Detoxing Microplastics

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/10/01

The benefits of kimchi for detoxing microplasticsWhat do you recommend my husband take to recover from Bell's Palsy? Follow-up on coronary artery inflammation question

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38:52

Q&A with Leyla, Part 2: Benefits of Pilates

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/10/01

The benefits of PilatesWhat does it mean that certain brands of nattokinase are "free of K2"?Should I avoid soy products due to my history of breast cancer?How can I choose the best fish oil? Is there a certain dose you recommend?Is there any other supplement I can take besides 5-HTP for mood? What about SAMe?Is there any relief for my friend with ulcerative colitis?

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22:05

Decoding Omega-3 Benefits: A Discussion with the...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/30

Fish Oil, Full-Spectrum Omega-3s, and Immunometabolism with Dr. Jeffrey Bland: Dr. Ronald Hoffman interviews Dr. Jeffrey Bland, founder of the Personalized Lifestyle Medicine Institute and Big Bold Health, about fish oil and omega-3 science. Bland recounts becoming involved with commercial fish oil in 1980 while promoting MaxEPA amid the “fat is bad” era and discusses Greenland Inuit research showing high omega-3 blood levels and low heart disease. They contrast whole-food omega-3 intake

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29:10

Decoding Omega-3 Benefits: A Discussion with the...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/30

Dr. Hoffman continues his conversation with Dr. Jeffrey Bland, founder of the Personalized Lifestyle Medicine Institute and Big Bold Health, about fish oil and omega-3 science.

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27:53

How’s Your Cholesterol Level? Why Your LDL Numbers...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/29

Cholesterol Beyond the Basics: ApoB, Lp(a), Stress, and Aged Garlic Extract for Cardiovascular Risk: Dr. Ronald Hoffman interviews clinical pharmacist and nutritionist Jim LaValle about cardiovascular risk factors beyond total cholesterol, emphasizing that blood tests measure lipoprotein particles and subfractions rather than cholesterol itself. They discuss limitations of relying on surrogate markers, the role of lifestyle (diet, exercise, sleep, stress, glucose control), and advanced

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26:51

How’s Your Cholesterol Level? Why Your LDL Numbers...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/29

Dr. Hoffman continues his conversation with clinical pharmacist and nutritionist Jim LaValle about cardiovascular risk factors beyond total cholesterol.

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35:23

Intelligent Medicine Radio for September 26, Part 1:...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/28

We take the keys away from older drivers—why not older doctors? Nearly 3 in 4 Americans battling this health problem—fatigue! What super-agers over 100 have in common—a hyper-vigilant immune system guarding against cancers and infections. How does “anabolic resistance” contribute to frailty—and what to do about it? Recurrent bouts of “burning sensations” on the face—diagnosis please?

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34:26

Intelligent Medicine Radio for September 26, Part 2:...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/28

Deadline looms for ban on hemp-derived CBD/THC products—while legal pot proliferates; Scientists disclose IBD benefits of urolithin A; “Dry-fasting” is a new fad—is it healthy? Short “exercise snacks” to break up prolonged inactivity benefit attention and cognition; Kimchi and designer probiotics show promise for flushing out microplastics; LSD soon to be approved as a prescription for anxiety.

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25:11

Leyla Weighs In: The Connection Between Sleep Cycles,...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/25

Sleep, Growth Hormone, and Autophagy: How Rest, Diet, and Fasting Support Metabolic Health and Longevity: Nutritionist Leyla Muedin discusses how deep, early non-REM sleep boosts growth hormone for muscle, bone, fat burning, and metabolic health, and reviews a Cell study in which UC Berkeley researchers mapped hypothalamic circuits and feedback through the locus coeruleus showing a tight balance between sleep, growth hormone release, and wakefulness, with implications for metabolic disease

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22:11

Culinary Medicine in Focus: Teaching Tomorrow's...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/22

Teaching Nutrition to Doctors: Dr. Nate Wood, MD, inaugural director of Culinary Medicine at Yale School of Medicine, discusses the persistent lack of nutrition education in medical training. Wood defines culinary medicine as combining nutrition science, medicine, education, and culinary skills to help patients and trainees cook health-promoting food. He reviews diet’s broad impact on chronic disease (cardiometabolic disease, dementia, cancer, mental health, MS), challenges in nutrition

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23:16

Culinary Medicine in Focus: Teaching Tomorrow's...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/22

Dr. Hoffman continues his conversation with Dr. Nate Wood, MD, inaugural director of Culinary Medicine at Yale School of Medicine.

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35:23

Intelligent Medicine Radio for September 19, Part 1:...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/21

MDs react to JAMA op-ed claiming autonomous AI will outperform doctors on routine medical tasks by 2030, spurring widespread layoffs: When even intravenous iron isn’t enough to stave off anemia; “Emergency “ home medical kits draw ire of medical experts: Meta dinged $567 for teen addiction—why spending it for therapy of adolescents who are hooked on social media may be a waste of money; Adequate vitamin D minimizes post-op pain; When is a second prostate biopsy called for?

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35:20

Intelligent Medicine Radio for September 19, Part 2:...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/21

Cancer rise in younger adults may be explained by accelerated cellular aging; “Quadriceps activation failure” may explain common waking difficulty following successful knee replacement; Is “Calocurb” a good natural alternative to GLP-1 drugs? New study claims 4 to 6 servings of whole grains may be the key to heart health—but doubts arise due to its authorship in Iran, a hotbed of scientific research fraud; Splenda back in the crosshairs as new evidence points to genetic damage; Bright

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23:49

Leyla Weighs In: The Balance of Cardio and...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/18

Concurrent Training for Healthy Aging and the Overlooked B12 Risk of Metformin: Nutritionist Leyla Muedin discusses how concurrent training—combining cardio and strength work—supports healthy aging by building endurance, preserving muscle, and maintaining independence and “healthspan.” She explains that aerobic exercise improves cardiorespiratory efficiency while resistance training preserves lean tissue and functional strength, and offers practical scheduling tips: place strength sessions

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34:31

Q&A with Leyla, Part 1: AI and The Future of Medicine

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/17

Autonomous Artificial Intelligence (AI) and the future of medicineAre there any alternative ways to lower my blood pressure other than taking prescription medication?

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32:45

Q&A with Leyla, Part 2: The Coronary Artery...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/17

As soon as I take my blood pressure meds, I get tired and lack energy for the rest of the day. What gives?I'm 77 and have Sjögren's syndrome. Can I take carnitine? How much should I take?Are there cardiac side effects to berberine? Both my husband and I take it for blood sugar.What types of protein are most helpful for osteoporosis and weight gain?The coronary artery inflammation controversy

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30:05

A Comprehensive Look at Immunity and Supplementation,...

Intelligent Medicine with Dr. Ronald Hoffman | The... ·

2026/09/16

Innate–Adaptive Balance and BWH 85 Beta-Glucan with Functional Medicine Physician Dr. Rob Rountree: He brings a nuanced view of immunity that rejects the simple “immune boosting” dimmer-switch model and emphasizes immune regulation and readiness. He reviews innate immunity as sentinel cells using pattern recognition receptors (e.g., macrophages) and explains how innate and adaptive systems interface, with innate signaling training adaptive responses; chronic inflammatory disease is framed

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