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PODCAST

Hormones, Metabolism & You!

Your hormones controleverything—from energy levels to weight, mood, and overall health. But understanding them shouldn’t feel like decoding a medical textbook. Welcome toHormones, Metabolism & You!, the podcast where board-certified endocrinologist Dr. Cassie Smith breaks down the science behind your body’s most powerful regulators. Each week, Dr. Smith tackles the real questions about metabolism, weight management, thyroid health, menopause, PCOS, insulin resistance, and more—giving you clear,

health & fitness medicine

All Episodes

60:03

131: Cell Care Over Self-Care: A New Way to Think...

Hormones, Metabolism & You! ·

2026/10/04

Dr. Monisha Bhanote joins me to talk about cellular health and resilience, and why fatigue, brain fog, digestive issues, and other everyday symptoms may be signals from our cells rather than things we should simply accept. We talk about her approach to cell care, cellular consciousness, and why health practices need to be personalized rather than copied from the latest trend.We also explore why Dr. Bhanote considers travel a stress test for the body, how digestion, immunity, focus, energy, and

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61:06

130: Why Your Hormone Protocol Isn’t Working: Mold,...

Hormones, Metabolism & You! ·

2026/09/27

What happens when you’re doing all the “right” things for your hormones and health, but you still don’t feel better? In this episode, I sit down with Dr. Neil Nathan to explore why underlying factors like mold, Lyme disease, inflammation, nervous system dysregulation, and detoxification challenges may complicate treatment. We also talk about why some patients react unexpectedly to hormones or supplements, how Dr. Nathan approaches complex chronic illness, and why looking beyond the obvious

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49:16

129: Why Is Testosterone Still Off-Limits for Women?

Hormones, Metabolism & You! ·

2026/09/20

Testosterone in women is finally getting more attention, but what does that actually mean for women and their care? In this episode, I sit down with Dr. Terri DeNeui to discuss the FDA’s focus on testosterone, why there still isn’t an FDA-approved testosterone treatment specifically for women, and the questions surrounding safety, dosing, and access.We also talk about symptoms of testosterone deficiency, why “normal” lab ranges don’t always tell the full story, and the larger conversation around

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43:06

128: Viral Hormone Trends: What’s Actually Worth Your...

Hormones, Metabolism & You! ·

2026/09/13

Social media is full of hormone hacks promising better energy, easier weight loss, balanced hormones, and fewer symptoms. But how much of it is actually backed by science? In this episode, I’m breaking down seven viral trends, including cortisol cocktails, fiber maxing, pink salt, metabolism morning routines, and “hormone-balancing” foods, and separating reasonable health habits from overhyped claims.I also talk about the way social media approaches PCOS and perimenopause, and why oversimplifying

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48:07

127: Birth Control Masterclass: The Mash-Up Every...

Hormones, Metabolism & You! ·

2026/09/06

In this mash-up episode, I’m bringing together key conversations about birth control, PCOS, PMS, and the hormonal changes women experience from their 20s through perimenopause.We unpack why birth control is so often used to manage symptoms, what it may be masking, and how hormones like estrogen, progesterone, testosterone, insulin, and cortisol all fit into the bigger picture. We also talk about the different birth control options women may consider as they get older and why the right approach can

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48:42

126: Health Care is So Broken - 3 Typical Patient Cases

Hormones, Metabolism & You! ·

2026/08/30

The healthcare system is not designed to keep you well, and I am done pretending that is okay. In this episode, I am breaking from the usual format to talk honestly about why I believe healthcare in the United States has become so reactive instead of preventative, and how that approach is leaving people sick, frustrated, and without answers. I share my perspective as both a patient and a provider, including the ways insurance companies, healthcare systems, limited appointment times, and a

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66:21

125: How to Dementia-Proof Your Brain: Dr. David...

Hormones, Metabolism & You! ·

2026/08/23

What if protecting your brain starts decades before memory problems ever appear? In this conversation, I sit down with neurologist and bestselling author Dr. David Perlmutter to talk about what current research says about dementia prevention, why metabolic health may play a much larger role than many people realize, and why waiting until cognitive symptoms develop may be waiting too long. We get into the connection between blood sugar, insulin resistance, inflammation, gut health, sleep, exercise,

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51:09

124: Heart Disease Myths Exposed: Statins, LDL,...

Hormones, Metabolism & You! ·

2026/08/16

Heart disease is still the leading cause of death, yet many people are left wondering whether they're focusing on the right risk factors.In this episode, I sit down with board-certified cardiac surgeon Dr. Philip Ovadia to discuss how his perspective shifted from treating advanced heart disease in the operating room to helping people prevent it in the first place. We talk through common questions about cholesterol, LDL, statins, coronary calcium scores, and why he believes heart health requires

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65:22

123: Hashimoto’s, Thyroid Labs, and Exercise: Are You...

Hormones, Metabolism & You! ·

2026/08/09

If you have Hashimoto’s and feel like you’re doing everything “right” but somehow feeling worse, this episode is for you. I’m answering your most frequently asked questions about Hashimoto’s, exercise, thyroid labs, thyroid antibodies, medication adjustments, estrogen, and why symptoms don’t always match what your lab work says. Throughout our conversation, I explain why looking at one lab value or one symptom in isolation often leads to frustration, and why understanding the bigger picture is

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47:30

122: Drain Before You Detox: The Missing Link Between...

Hormones, Metabolism & You! ·

2026/08/02

If you're dealing with constipation, bloating, brain fog, or you feel like every detox protocol makes you feel worse instead of better, this conversation is for you.In this episode, I'm joined by Marina Ortega, founder of Scottsdale Hydrotherapy and co-founder of Trust Your Gut, to talk about one piece of healing she believes is often overlooked: supporting your body's drainage pathways before asking it to detox. Marina shares her own journey through chronic constipation, mold exposure, and years

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48:17

121: Why Successful Men Are Secretly Running...

Hormones, Metabolism & You! ·

2026/07/26

What does it really mean when a man starts feeling constantly exhausted, loses motivation, struggles with brain fog, or notices changes in his physical and sexual health?In this episode, I sit down with Dr. Stephen Sanders, founder of Whole Men's Health, to talk about why these symptoms deserve more attention and why men's health is about far more than testosterone alone. We discuss the growing number of younger men experiencing hormone and metabolic challenges, how stress, sleep, nutrition,

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33:00

120: From PCOS to PMOS; Why Hormones Are Not the Only...

Hormones, Metabolism & You! ·

2026/07/19

In this interview with Terri DeNeui, we explore why the conversation around PCOS is shifting toward a broader understanding of metabolic health with the emerging term PMOS. Rather than viewing irregular cycles, infertility, and hormone imbalances as isolated ovarian problems, we discuss how insulin resistance, gut health, inflammation, stress, and lifestyle factors may be driving many of the symptoms women experience. I also share why this updated perspective could change the way clinicians

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59:44

119: Beyond Sick Care: Why Insurance Isn’t Coming To...

Hormones, Metabolism & You! ·

2026/07/12

For many people, the healthcare system becomes frustrating long before they receive a diagnosis. Symptoms are dismissed, lab work comes back "normal," and the next step is often another prescription rather than a conversation about why those symptoms developed in the first place. In this episode, I'm joined by board-certified anesthesiologist and hormone optimization specialist Dr. Mike Fortunato to discuss his journey from conventional medicine into functional medicine, and why he believes many

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54:36

118: Stop Starving, Start Healing: The Real Root...

Hormones, Metabolism & You! ·

2026/07/05

What if the reason you're struggling with weight, low energy, or hormone symptoms isn't just about eating less and exercising more? In this episode, I sit down with functional medicine practitioner Dani Conway to talk about the bigger picture of metabolic health. We discuss why so many women are told their lab work is "normal" even when they still feel exhausted, inflamed, or stuck, and why looking beyond the scale often leads to better answers. Dani shares how her own health journey shaped the

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53:57

117. Perimenopause Is Wild: Symptoms, Support, and...

Hormones, Metabolism & You! ·

2026/06/28

Perimenopause and menopause affect every woman, yet many are still caught off guard by the wide range of symptoms that can come with this stage of life. In this episode, I sit down with nutritionist, menopause researcher, and author Andrea Donsky to discuss what she's learned from studying thousands of women and why so many continue to feel confused, dismissed, or unsupported when seeking answers. We explore common symptoms like fatigue, brain fog, sleep disruption, anxiety, memory issues, and

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57:40

116: What Screen Time Is Really Doing to Your Eyes,...

Hormones, Metabolism & You! ·

2026/06/21

One of the most overlooked aspects of health may be influencing how you think, learn, focus, perform, and even respond to stress every single day. In this episode, I sit down with neuro-optometrist Dr. Bryce Appelbaum to explore the difference between eyesight and vision, and why seeing 20/20 doesn't necessarily mean your visual system is functioning optimally. We discuss how the eyes and brain work together, the role vision plays in learning, reading, athletic performance, spatial awareness, and

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42:55

115: PCOS Has a New Name: Why It’s More Than an...

Hormones, Metabolism & You! ·

2026/06/14

In this episode, I explain why PCOS is now better understood as Polyendocrine Metabolic Syndrome (PMOS).While the traditional name focuses on the ovaries, the reality is that this condition often extends far beyond reproductive health. I discuss why many women with PCOS don't actually have ovarian cysts, how the condition can affect everything from insulin and metabolism to cortisol, inflammation, gut health, and hormone balance, and why this updated framework may lead to more accurate diagnoses

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66:50

114. Why Your Brain Feels Drained... and How to Reset...

Hormones, Metabolism & You! ·

2026/06/07

In this episode, I sit down with Dr. Patrick Porter, founder of BrainTap and a longtime researcher in brain fitness and human performance, to explore why so many people today are struggling with brain fog, poor focus, low energy, and chronic stress. We discuss the relationship between the brain, gut, and nervous system, and how modern life may be affecting the way we think, feel, and function. Dr. Porter shares his perspective on brain fitness, why recovery is just as important as stress itself, and

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44:42

113: Why Cholesterol Isn’t the Villain and Estrogen...

Hormones, Metabolism & You! ·

2026/05/31

For years, cholesterol numbers have been treated as one of the primary indicators of heart health, but are we focusing on the right markers? In this episode, I sit down with Dr. Terri DeNeui to discuss the bigger picture behind cardiovascular risk. We talk through the limitations of looking at LDL cholesterol in isolation, the importance of factors like inflammation, insulin resistance, ApoB, lipoprotein(a), calcium scores, and lifestyle habits, and why a more comprehensive assessment may be

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25:54

112: The Birth Control Conversation We Need to Have:...

Hormones, Metabolism & You! ·

2026/05/24

What if the birth control pill you’ve been told is safe for decades is affecting far more than just pregnancy prevention? In this episode, I sit down with OB-GYN Dr. Johnny Peet for a powerful and nuanced conversation about oral birth control, hormone health, and the risks many women are never fully informed about, especially as they enter their 40s and 50s. We unpack the real differences between oral contraceptives and progesterone-only IUDs, why birth control pills can impact testosterone, mood,

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131 results

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