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PODCAST

The Rounds Table

Dr. John Fralick and Dr. Michael Fralick

The Rounds Table is a free recurring medical podcast covering the latest and most important research from major medical journals. It is intended for all practicing healthcare professionals and aims to to help them keep up to date in the care of their patients.

science life sciences

All Episodes

5:34

Episode 137 - Fecal Transplant in Primary C. difficile

The Rounds Table ·

2025/10/02

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining fecal microbiota transplantation (FMT) in primary C. difficile infection. Here we go! Fecal Microbiota Transplantation Versus Vancomycin for Primary Clostridioides difficile Infection: A Randomized Controlled Trial (0:00 – 4:47).The Good Stuff (4:48 – 5:36): The I'm Pharmacy podcast, now featured on https://medicinepods.c...

en-ca

22:53

Episode 135 - Top Papers from the 2025 European...

The Rounds Table ·

2025/09/18

Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Drs. Mike and John Fralick discuss some of the top papers from the 2025 European Society of Cardiology (ESC) Congress. Hot off the presses, here we go! Increasing the Potassium Level in Patients at High Risk for Ventricular Arrhythmias (0:00 - 5:23)Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (5:24 - 10:23)RSV Prefusion F Vaccine for Prevention of Hospi...

en-ca

36:45

Episode 134 - Rounds Table x I'm Pharmacy: Tableside...

The Rounds Table ·

2025/09/11

Send us a text Welcome back Rounds Table Listeners! This week, Dr. Mike Fralick sits down with Dr. Mina Tadrous, a pharmacist, researcher, Assistant Professor at the University of Toronto's Leslie Dan Faculty of Pharmacy, and host of the I'm Pharmacy podcast. If you're curious about what it takes to run a podcast, musings on the future of AI and drug discovery, and whether Mike can hold his own in a 90's-style rap battle, this is a conversation you don't want to miss. Here we go! Check out th...

en-ca

11:19

Episode 133 - Dexamethasone for Bacterial Meningitis

The Rounds Table ·

2025/09/04

Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a throwback trial of dexamethasone in adults with acute bacterial meningitis. Here we go! Dexamethasone in Adults with Bacterial Meningitis (0:00 – 11:19).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

en-ca

10:24

Episode 132 - Mifepristone for Type 2 Diabetes and...

The Rounds Table ·

2025/08/28

Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the effects of mifepristone on glycemic control in adults with inadequately controlled type 2 diabetes and hypercortisolism. Here we go! Inadequately Controlled Type 2 Diabetes and Hypercortisolism: Improved Glycemia With Mifepristone Treatment (0:00 – 10:24).Questions? Comments? Feedback? We’d love to hear from you! @roundstable ...

en-ca

23:17

Episode 130 - Hypotension-Avoidance vs...

The Rounds Table ·

2025/08/14

Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go! Effects of...

en-ca

10:28

Episode 128 - Finerenone with SGLT2 inhibitors for...

The Rounds Table ·

2025/07/24

Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28) Trainees, med ...

en-ca

22:48

Episode 127 - Leukocytoclastic Vasculitis with Karim...

The Rounds Table ·

2025/07/17

Send us a text Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. Karim Ladak—rheumatologist and internist, Clinical Assistant Professor at McMaster University, and host of the Rheumatology for the Royal College podcast—to talk about leukocytoclastic vasculitis. Here we go! Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

en-ca

6:34

Episode 126 - Sotatercept for Pulmonary Arterial...

The Rounds Table ·

2025/07/10

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial exploring the effects of add-on sotatercept in patients with advanced pulmonary arterial hypertension and a high risk of death. Here we go! Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death (0:00 – 5:38).The Good Stuff: 2025 Scripps National Spelling Bee winning word: éclaircissement (5:39 - 6:34)Q...

en-ca

21:57

Episode 125 - Top Papers from the 2025 American...

The Rounds Table ·

2025/07/03

Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go! Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial (0:00 - 6:05)Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes (6:06 - 13:22)Stem Cell–...

en-ca

25:33

Episode 124 - 2024 KDIGO Clinical Practice Guidelines...

The Rounds Table ·

2025/06/26

Send us a text Welcome back Rounds Table Listeners! Today we have the next episode in our Clinical Practice Guidelines series. Drs. Mike and John Fralick discuss the top takeaways from the 2024 KDIGO Clinical Practice Guidelines for chronic kidney disease. Here we go! 1. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (0:00 - 24:24) Access the KDIGO 2024 "Top 10 Takeaways" PDFs here: https://kdigo.org/guidelines/ckd-evaluation-and-manage...

en-ca

14:19

Episode 123 - Trial Files Top 5 RCTs

The Rounds Table ·

2025/06/19

Send us a text Welcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15 minutes. Here we go! 1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 - 3:08) 2. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (3:09...

en-ca

8:40

Episode 122 - Opioids vs. Non-Opioids for Chronic...

The Rounds Table ·

2025/06/12

Send us a text Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids versus non-opioids for chronic pain; IV albumin for renal impairment and mortality; and omeprazole before endoscopy in patients with GI bleed. Three trials, 9 minutes, here we go! 1. Effect of Opioid vs Non...

en-ca

7:50

Episode 118 - Lorundrostat for Uncontrolled Hypertension

The Rounds Table ·

2025/05/15

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the safety and efficacy of lorundrostat (an aldosterone synthase inhibitor) in treatment of uncontrolled and treatment-resistant hypertension. Here we go! Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension (0:00 – 7:02).The Good Stuff: Trial Files, a free monthly newsletter on practice-changing tr...

en-ca

26:08

Episode 117 - Brensocatib for Bronchiectasis and...

The Rounds Table ·

2025/05/08

Send us a text Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast. This week, Dr. Mike Fralick and special guest Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration discuss two recent papers: the use of brensocatib (a DPP-1 inhibitor) to treat bronchiectasis, and the effect of alteplase administered 4.5 to 24 hours after stroke in patients with mild posterior circulation stroke who did not receive thrombectomy. ...

en-ca

11:23

Episode 115 - Tirzepatide for Obesity Treatment and...

The Rounds Table ·

2025/04/24

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go! Tirzepatide for Obesity Treatment and Diabetes Prevention (0:00 – 10:24).The Good Stuff: We've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here!&nb...

en-ca

9:15

Episode 113 - Vitamin D in Clinically Isolated...

The Rounds Table ·

2025/04/10

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go! High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).Announcements (7:36 – 9:15): Canadian ...

en-ca

22:25

Episode 107 - Point-of-Care Diabetes Management in...

The Rounds Table ·

2025/02/20

Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers - the role of continuous glucose monitoring for diabetes management in hospital and the benefit of tirzepatide in patients with heart failure with preserved ejection fraction and obesity. Two papers, here we go! Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity (0:00 – 11:26).DIATEC: A Randomized Controlled Trial (...

en-ca

18:36

Episode 106 - Screening for Diabetes and Dyslipidemia...

The Rounds Table ·

2025/02/19

Welcome back Rounds Table Listeners! We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat about her hot-off-the press publication - Population-Level Screening for Diabetes and Dyslipidemia After Pregnancies Complicated by Hypertension or Diabetes! Questions? Comments? Feedback? We’d love to hear from you! @ro...

en-ca

9:11

Episode 105 - Intravenous Thrombolysis in Minor...

The Rounds Table ·

2025/02/13

Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick! This week, he will discuss a paper exploring the role of intravenous thrombolytic therapy in patients with minor ischemic stroke and intracranial vessel occlusion. Here we go! Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open-label, phase 3 superiority trial (0:00 – 6:18).And for the Good Stuff: Trial Files (6:18 – 7:59).Questions?...

en-ca

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