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PODCAST

NeuroFrontiers

Clinical research and advancements furthering clinicians’ ability to diagnose and treat neurological disorders never stop. And neither does NeuroFrontiers, a series dedicated to covering them all. Here neurology specialists will find essential updates on conditions affecting the nervous system, spinal cord, and overall brain health. So if you want to stay up to date on the latest clinical research and news on neurological disorders, then look no further. Because NeuroFrontiers is where neurology

science & medicine medicine

All Episodes

00:00:00

Understanding Antibody-Mediated Demyelinating...

NeuroFrontiers ·

2025/09/29

Guest: Michael Levy, MD, PhD Antibody-mediated demyelinating diseases, such as neuromyelitis optica spectrum disorder and MOG antibody disease, differ fundamentally from multiple sclerosis (MS) due to their association with specific antibodies. Dr. Michael Levy explains how these conditions progress, how relapses can drive disability, and why prevention is critical for improving long-term outcomes. Dr. Levy is an Associate Professor at Harvard Medical School working in the

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00:00:00

Navigating MS Diagnosis in Older Adults:...

NeuroFrontiers ·

2025/09/29

Guest: Le Hua, MD Diagnosing multiple sclerosis (MS) in older patients presents unique challenges, especially as age-related comorbidities and common neurological findings often mimic MS. Hear from Dr. Le Hua as she highlights the importance of thorough clinical history, cautious interpretation of imaging, and the role of paraclinical studies in ensuring accurate MS diagnosis, particularly in patients over 50. Dr. Hua is the Director of Clinical Operations and Director of the Multiple

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00:00:00

Genetic Pathways in MS: The Clinical Impact of a...

NeuroFrontiers ·

2025/09/29

Guest: Sergio Baranzini, PhD In a landmark study involving over 10,000 patients, the International MS Genetics Consortium (IMSGC) has identified the first genetic variant associated with disease severity in multiple sclerosis (MS). Dr. Sergio Baranzini, a Distinguished Professor of Neurology at the University of California, San Francisco Weill Institute for Neurosciences, explains what's next in researching this variant and working towards effective treatments. Dr. Baranzini

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00:00:00

MMN in Practice: A Rare Motor Neuropathy Often...

NeuroFrontiers ·

2025/09/23

Host: Jennifer Caudle, DO Guest: Katie Beadon, MD, MASc, FRCPC Multifocal motor neuropathy (MMN) is a chronic, immune-mediated motor neuropathy that can mimic other neuromuscular disorders1-3 and is one of the few motor neuron disorders that is treatable.4 However, disease severity correlates with the length of time a patient remains untreated, which is why early recognition and treatment initiation is essential for preserving long-term motor function.5-6 Joining Dr. Jennifer

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00:00:00

Decoding Disability Worsening in MS: The Case for...

NeuroFrontiers ·

2025/09/17

Host: Ryan Quigley A new multicenter study highlights how serum and CSF biomarkers can refine prognostic accuracy and guide treatment strategies in multiple sclerosis (MS). ReachMD's Ryan Quigley explains key findings and provides insights on how integrating these biomarkers at diagnosis could move MS care toward more personalized and effective interventions. This topic was also discussed at the 2025 Congress of the European Committee for Treatment and Research in Multiple Sclerosis

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00:00:00

The Future of MS Management: Novel Agents and...

NeuroFrontiers ·

2025/08/26

Guest: Marisa McGinley, DO The multiple sclerosis (MS) treatment landscape is rapidly evolving, with novel approaches on the horizon that may transform care for progressive patients. Explore the latest phase 3 data on BTK inhibitors like tolebrutinib and gain insights into ongoing CAR T-cell and remyelination research, including the BEAT-MS trial, with Dr. Marisa McGinley, a neurologist at the Cleveland Clinic.

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00:00:00

Recognizing MS: Understanding Symptoms and Avoiding...

NeuroFrontiers ·

2025/08/20

Early symptoms of multiple sclerosis (MS) often present as clear, localized neurological changes lasting several days. However, many nonspecific complaints and common MRI findings can mimic MS, leading to misdiagnosis and unnecessary treatment. Dr. Jonathan Howard, an Associate Professor of Neurology and Psychiatry at the NYU Grossman School of Medicine and the Director of the Neurology Service at Bellevue Hospital, reviews hallmark symptom patterns, explains how to differentiate benign

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00:00:00

Modern MS Care: Navigating Treatment Options for...

NeuroFrontiers ·

2025/08/20

Since 2010, the landscape of multiple sclerosis care has transformed to encompass a variety of medications, each having unique benefits, risks, and side effect profiles. Dr. Jonathan Howard discusses how to match treatment strength to disease severity and balance patient risk tolerance with evolving therapeutic options, from long-standing injectables to infusions and oral therapies. Dr. Howard is an Associate Professor of Neurology and Psychiatry at the NYU Grossman School of Medicine and

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00:00:00

Epigenetic Immune Signatures in Alzheimer’s:...

NeuroFrontiers ·

2025/08/19

Guest: David Gate, PhD Patients with Alzheimer's disease—especially APOE4 carriers—show distinct epigenetic immune alterations that may influence disease progression, treatment response, and side effect risk. In this episode, Dr. David Gate, an Assistant Professor of Behavioral Neurology at Northwestern University, dives into his research on this subject and explains how chromatin accessibility in proinflammatory genes and T-cell receptor changes link to neurological pathology.

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00:00:00

Epigenetic Immune Signatures in Alzheimer’s:...

NeuroFrontiers ·

2025/08/19

Guest: David Gate, PhD Patients with Alzheimer's disease—especially APOE4 carriers—show distinct epigenetic immune alterations that may influence disease progression, treatment response, and side effect risk. In this episode, Dr. David Gate, an Assistant Professor of Behavioral Neurology at Northwestern University, dives into his research on this subject and explains how chromatin accessibility in proinflammatory genes and T-cell receptor changes link to neurological pathology.

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00:00:00

Shaping the Future of MS Care: Novel Agents and...

NeuroFrontiers ·

2025/08/14

Guest: Marisa McGinley, DO The MS treatment landscape is rapidly evolving, with novel approaches on the horizon that may transform care for progressive patients. Explore the latest phase 3 data on BTK inhibitors like tolebrutinib and gain insights into ongoing CAR T-cell and remyelination research, including the BEAT-MS trial, with Dr. Marisa McGinley, a neurologist at the Cleveland Clinic.

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00:00:00

Advancing MS Care: Evolving Treatments and...

NeuroFrontiers ·

2025/08/14

Guest: Marisa McGinley, DO Multiple sclerosis (MS) treatment has transformed dramatically, with a wide range of high-efficacy options currently available. Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, explores how advancements in drug availability, administration methods, and efficacy are reshaping care, with a focus on sequencing strategies and the growing movement toward early, aggressive treatment. Learn how to integrate patient preferences, comorbidities, and shared

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00:00:00

Understanding MS: Managing Hidden and Overlooked...

NeuroFrontiers ·

2025/08/14

Guest: Marisa McGinley, DO Multiple sclerosis (MS) presents with far more than just mobility issues—fatigue, spasticity, bladder and bowel dysfunction, cognitive changes, and mood disorders are frequently underrecognized but deeply impactful. Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, explains how to identify subtle clinical changes, utilize patient-reported outcomes, and engage in proactive symptom discussions that support timely interventions.

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00:00:00

Multidisciplinary Approaches to MS: Enhancing Care...

NeuroFrontiers ·

2025/08/14

Guest: Marisa McGinley, DO Multiple sclerosis (MS) presents a diverse range of symptoms, requiring coordinated expert care. Hear from Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, as she provides practical strategies for neurologists to serve as the central point of contact for patients with MS and engage with specialty teams to provide personalized care.

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00:00:00

Recognizing the Full Spectrum of MS Symptoms:...

NeuroFrontiers ·

2025/08/13

Guest: Marisa McGinley, DO Multiple sclerosis presents with far more than mobility challenges—many symptoms are subtle, hidden, and easily overlooked. MS manifestations can range from fatigue, spasticity, and bladder issues to cognitive changes, mood disorders, and overlapping comorbidities. Join Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, as she shares practical strategies for early detection, patient-centered diagnosis, and symptom monitoring.

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00:00:00

Recognizing the Full Spectrum of MS Symptoms:...

NeuroFrontiers ·

2025/08/13

Guest: Marisa McGinley, DO Multiple sclerosis (MS) presents a diverse range of symptoms that require coordinated, expert care. Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, provides practical strategies for neurologists to serve as the central point of contact for patients with MS, initiate targeted treatments, and engage a variety of specialty teams in collaborative management.

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00:00:00

Tuning the Brain: Personalized Anxiety Relief with...

NeuroFrontiers ·

2025/06/30

Guest: John Golden Guest: Michael Greenberg, MD EEG-guided headphones from Vital Neuro present a new frontier in anxiety management through personalized, real-time neurofeedback and music therapy. Dr. Michael Greenberg speaks with Vital Neuro CEO John Golden about the science behind these devices, their effectiveness in reducing anxiety symptoms, and how they can integrate into daily life.

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00:00:00

Transforming Clinician Wellness: EEG Headphones...

NeuroFrontiers ·

2025/06/30

Guest: John Golden Host: Michael Greenberg, MD Neuro-responsive EEG headphones are helping healthcare professionals combat burnout by promoting calm, focus, and resilience. Backed by neuroscience and real-time brain monitoring, this personalized technology blends music and neurofeedback to optimize mental states and reduce stress. Hear from Vital Neuro CEO John Golden as he joins Dr. Michael Greenberg to discuss this device's impact in clinical workflows, from pre-op anxiety

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00:00:00

Innovations in Bladder Monitoring for MS: Advancing...

NeuroFrontiers ·

2025/06/03

Guest: Riley Bove, MD, MMSc Many patients with multiple sclerosis (MS) experience neurogenic bladder symptoms—ranging from urgency and incontinence to retention and infection risk—but these issues are often underprioritized in care. Based on recent research, remote, commercially available bladder monitoring tools can help address this unmet need and uncover day-to-day fluctuations in bladder function. To learn more about this research, tune in to hear from Dr. Riley Bove. Not only is

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00:00:00

How Diagnostic Delays in gMG Impact Disease Severity,...

NeuroFrontiers ·

2025/06/03

Guest: John A. Morren, MD, FAAN, FAANEM The symptom variability, prolonged asymptomatic periods, and inconsistent presentations of generalized myasthenia gravis (gMG) often lead to significant diagnostic delays and misdiagnoses. Based on recent studies, these delays then correlate with increased disease severity, longer time to symptom control, and worsened quality of life. Here to help uncover the hidden toll of diagnostic delays on patients with gMG is Dr. John Morren. He’s the

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