x

75% of people globally want unbiased news (Pew Research) but are concerned they're not getting that.

Get balanced coverage with Symby. See how stories are covered across diverse outlets and spot when one side covers a story the other skips.

PODCAST

Discovery Matters

Discovery Matters

A collection of stories and insights on matters of discovery that advance life sciences. Brought to you by the curious people at Cytiva.

science life sciences

All Episodes

00:38:55

108. Metastatic breast cancer

Discovery Matters ·

2025/10/09

This episode is all about the purisuit to understand and treat metastatic breast cancer. Dr. Martine Piccart and Dr. Lisa Carey delve into the complexities of metastatic breast cancer (MBC), highlighting why it remains one of the most challenging forms of the disease to treat.

en

00:43:27

103. How space impacts the body

Discovery Matters ·

2025/04/25

Ever wonder what happens to your body when you leave Earth behind? In this gravity-defying episode, we launch into the weird, wild world of human biology in space. From the first C. elegans in space to the NASA Twins Study to future deep space missions, we have a lot to discuss. Strap in as we float through the science of space adaptation. Spoiler: space may teach us about our Earth-bound health. Show notes• Deane, Colleen S, et al. (2023) Comparative analysis of muscle atrophy during spaceflight,

en

00:27:13

102. Fighting diabetes differently

Discovery Matters ·

2025/03/27

What's new with insulin? Jeppe Sturis and his team at Novo Nordisk have a new hypothesis. They challenge the long-held belief that insulin resistance comes from faulty tissues, suggesting instead that the real culprit is insulin breaking down before it even reaches its target. This fresh perspective could reshape how we fight diabetes.We will also hear from Diamyd Medical’s advancing research on antigen-specific immunotherapy which could change the game by protecting insulin-producing cells and

en

00:30:31

101. Unleashing AI: Adventures in discovery

Discovery Matters ·

2025/03/06

Join us for a fascinating deep dive into how generative AI is revolutionizing healthcare and life sciences! We unveil groundbreaking advancements in drug discovery, clinical trials, and diagnostics—showcasing AI’s growing role in shaping the future of medicine. With expert insights from Shweta Maniar (Google Cloud) and Martin Stumpe (Danaher), we’ll explore how AI accelerates innovation through data-driven breakthroughs while keeping humans at the heart of the process for trust and

en

00:18:27

99. Re-run: One hundred years of insulin

Discovery Matters ·

2024/12/23

Insulin's discovery in 1921 transformed diabetes from a certain death sentence to a manageable chronic condition, revolutionizing modern medicine. In this episode of Discovery Matters, we look back to our episode on a fascinating journey through 100 years of insulin advancements and its profound impact on diabetes treatment.Listen in to appreciate 100 years of ground-breaking science and anticipate what the future holds for diabetes treatment.

en

00:25:36

98. Detective work in Parkinson's Disease

Discovery Matters ·

2024/12/20

In this episode of Discovery Matters we delve into groundbreaking advancements in Parkinson’s disease research. Dodi and Conor transport us to the frontier of medical innovation, exploring the latest discoveries and techniques that hold promise for early diagnosis and treatment of Parkinson’s disease. Show notes • Decet, Marianna et al. ‘A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism’, Cell Reports Medicine, Volume 5, Issue 10. • Hällqvist, J.,

en

00:15:03

97. Re-run: The discovery of Protein A

Discovery Matters ·

2024/11/27

In this re-released episode we revisit protein A. We will dive back into the history and science of protein A. But what exactly sets protein A apart? Is it really the top choice for antibody purification because of its alphabetical ranking, or is there more to the story? And what about its counterparts, proteins G and L?

en

00:17:52

96. Re-run: Tea, jam and protein separation

Discovery Matters ·

2024/11/21

As we approach our one hundredth episode, travel back with us to the origins of the podcast in our premiere episode, "Team and Jam and Protein Separation." In this debut, we explored the vital process of protein separation—an essential technique in biochemistry and pharmaceuticals that continues to impact human health in significant ways.

en

00:20:24

95. Modality convergence in advanced therapies

Discovery Matters ·

2024/10/24

Join us as Dr. Aravind Asokan from Duke University explores cutting-edge technologies revolutionizing advanced therapies, including CRISPR, mRNA, viral vectors, and cell therapies. He shares key lessons from past challenges, discusses scalability, product quality, and how integrating various therapeutic approaches is shaping the future of disease treatment.This episode covers exciting advancements in AAV with CRISPR, CAR T cell therapy, circular RNA, and virus-like particles (VLPs). Show

en

00:27:06

93. How sustainable is biopharma?

Discovery Matters ·

2024/09/26

Eco-design, collaboration, circular economy. These are the bywords of sustainability in biopharma.Join Ryan Walker, Senior Director of Sustainability at Cytiva, and Aude Arkham, Global Head of Eco Design and Circular Economy at Sanofi, as they explore how eco-design and circular economy initiatives are shaping the future of healthcare. We delve into challenges, achievements, and the transformational potential of sustainability efforts within biopharma. From Sanofi’s life cycle assessments to

en

00:26:20

92. Big data, AI, and the problem of averages

Discovery Matters ·

2024/09/05

In this episode of "Discovery Matters," we dive into the powerful intersection of big data and artificial intelligence. Joined by Matej Macak, a partner from McKinsey, we unravel how AI and machine learning are revolutionizing our approach to finding new, effective medications.With Tom Yankeelov, Professor of Biomedical Engineering, Diagnostic Medicine, Oncology at the University of Texas for Austin, we'll explore the "problem of averages" and much more.

en

00:33:30

91. The body as a bioreactor

Discovery Matters ·

2024/08/22

What does 'the body as a bioreactor' mean? In this discussion how scientists use the body's machinery to produce therapeutic proteins. Scott Ripley, General Manager of Nucleic Acids at Cytiva, explains that traditional bioprocessing uses external bioreactors, while the new approach leverages the body's natural processes. This method offers benefits like longer protein half-life and the ability to express multiple proteins simultaneously. Justin Eyquem, assistant professor at

en

00:20:42

90. What's next for advanced therapies?

Discovery Matters ·

2024/08/08

We're diving into advanced therapies with industry leaders. Emmanuel Abate, President of Genomic Medicine at Cytiva discussed the strategies to accelerate clinical work and reduce costs. Nathaniel Wang, CEO and Co-Founder of Replicate Bioscience highlighted their ground breaking self-replicating RNA technology, showcasing impressive clinical results for a rabies vaccine. Both experts emphasized the momentum in biotech, the potential of AI in advancing science, and the importance of making

en

00:34:33

89. Advanced therapies

Discovery Matters ·

2024/05/21

From gene and cell therapies, to the use of CRISPR and other precision engineering technologies, this episode dives into the opportunities and challenges of the emerging field of advanced therapies.On Discovery Matters this week, Dodi and Conor are joined by Daria Donati, Chief Scientific Officer of Genomic Medicine at Cytiva, as well as Jen Moody, Vice President of External Innovation of Genomic Medicines at Danaher, to discuss the science, progress, and potential of advanced therapeutics

en

00:21:15

88. Replicants and reality

Discovery Matters ·

2024/04/30

Can you tell the difference between a human and AI? Of course you can…right? We challenge Conor and Dodi to tell the difference between Conor and Conor BOT all while uncovering how AI is transforming the life sciences.Uncover how AI is transforming the life sciences. Together with an AI-bot the pair explore the potential applications of AI in drug discovery, personalizing medical treatments, protein folding, and more. They also consider the ethical considerations required when developing AI models,

en

00:29:14

87. Cephalopods: From camouflage to communication

Discovery Matters ·

2024/04/11

Let's explore the remarkable colour-changing abilities of cephalopods. Joined by Dan Wilson from the Costas Research Institute at Northeastern University, the team dive into the fascinating research behind the development of paints that respond to environmental stimuli, such as sunlight. They also discuss titanium dioxide and how it acts as a facilitator of the colour-changing process. Professor Alon Gorodetsky, Associate Professor of Chemical and Biomolecular Engineering at the University of

en

00:29:40

86. Synthetic biology

Discovery Matters ·

2024/03/28

In this episode of Discovery Matters, hosts Dodi and Conor explore how synthetic biology can lead to transformative breakthroughs when it comes to dealing with global health problems. Through their conversation with Justin Vigar, a PhD student in Dr. Keith Pardee's lab at the University of Toronto in Canada, we learn how his paper-based diagnostic tool has the potential to provide faster, more cost-efficient, and accessible diagnostics for underserved locations. This is complemented by Amir

en

00:26:23

85. Drugging the undruggable

Discovery Matters ·

2024/03/14

Tune in to Discovery Matters to see how we can drug the undruggable. Dodi and Conor talk to Mark Bray, a second year PhD student in the Bowman Lab at the University of Pennsylvania, about the concept of “drugging the undruggable” for drug discovery and development. They discuss advances in medical research which has enabled us to drug molecular targets that were previously inaccessible, and the strategies that are used to devise and find effective drugs. Vicky Richon, CEO at Entact Bio, elucidates

en

00:30:25

84. Unraveling biotech's AI transformation

Discovery Matters ·

2024/02/23

Explore the potential of artificial intelligence (AI) and machine learning to revolutionize biomedical research and make personalized healthcare a reality.Tune in to Discovery Matters to see how AI and machine learning will be the future of biomedical research. Featuring interviews with Professor Kourosh Saeb-Parsy and Dr Namshik Han — leaders in the AI and biotech space — this episode delves into the significance of advanced technology for unlocking discoveries in transplantation, understanding

en

00:29:05

83. Antibody drug conjugates

Discovery Matters ·

2024/01/19

Let’s explore the world of antibody drug conjugates (ADCs) and their potential for improving human health. Our two guests—Principal Investigator Sasha Ebrahimi from GSK and oncologist Dr. Paolo Tarantino—discuss the development and advantages of ADCs, and how they can be used to personalize treatments for cancer and other illnesses. Sasha explains how ADCs combine the targeting capabilities of antibodies with the cytotoxic effects of drugs, while Dr. Tarantino delves into his research with breast

en

103 results

Similar Podcasts

Classic Radio Science Fiction

solgoodmedia.com

Mission to Mars

Inception Point Ai

The 365 Days of Astronomy

365DaysOfAstronomy.org

Creek Devil

william Jevning

UFO Chronicles Podcast

Nik Hunter