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PODCAST

Precision Medicine Made Simple

Welcome to the “Precision Medicine Made Simple Podcast,” where we simplify the complex world of precision medicine. We"re here to explore how personalized healthcare can empower you to understand and improve your health to live a longer and healthier life. Join us as we break down the latest in medical science into actionable insights. Let"s make precision medicine accessible and actionable for everyone. Sponsored by: Biography Health, where healthcare meets personalization. With their DNAbled™

health & fitness medicine

All Episodes

01:23:41

Optimizing Health Span: How Fitness, Sleep, and...

Precision Medicine Made Simple ·

2025/10/27

In this episode of Precision Medicine Made Simple, we’re joined by Dr. Mohammad Jarbou, co-founder of the Longevity Clinic. Dr. Jarbou, a board-certified physician in pulmonary medicine, critical care, sleep medicine, and clinical informatics, discusses how his clinic uses a holistic approach to aging and health span. The clinic focuses on prevention and early detection, utilizing personalized medicine, genetic testing, fitness plans, and sleep optimization.Dr. Jarbou explains how cutting-edge

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53:40

Understanding Polygenic Risk Scores: A Deep Dive into...

Precision Medicine Made Simple ·

2025/10/10

In this episode of Precision Medicine Made Simple, we’re joined by Dr. Jeff Gulcher, co-founder of Decode Genetics and current leader at Galateo Bio. Dr. Gulcher shares his vast experience in the field of genomics and precision medicine, covering everything from polygenic risk scores (PRS) to the challenges of integrating diverse genetic data into predictive healthcare.Dr. Gulcher takes us back to the early days of genetic research with Decode Genetics, where his team pioneered genome-wide

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41:52

Navigating Healthcare Complexity: DIY Testing, AI,...

Precision Medicine Made Simple ·

2025/09/26

In this episode of Precision Medicine Made Simple, we’re joined by Lucy Janoyan, the Chief Operations Officer and Chief Strategy Officer at Biography Health. Together with Taylor Cu, Lucy dives into a wide-ranging discussion on the state of healthcare, DIY testing, and the future of personalized care.Lucy and Taylor reflect on their experience at Rosetta Fest, where they explored the complexities of the healthcare system, the growing trend of employer-sponsored healthcare, and the role of digital

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36:53

Polygenic Risk Scores 101: A Key to Predicting and...

Precision Medicine Made Simple ·

2025/09/08

In this episode of Precision Medicine Made Simple, we welcome back Dr. Yelena Bykhovskaya, the Chief Scientific Officer at Biography Health, for a deep dive into polygenic risk scores (PRS) and their emerging role in precision medicine. Dr. Bykhovskaya breaks down the complexities of genetics and its application in clinical practice, focusing on how polygenic risk scores can be used to assess an individual's risk for common complex diseases.We discuss the evolution of genetics in healthcare, how PRS

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01:01:49

Why Performance Medicine Matters More Than Prevention

Precision Medicine Made Simple ·

2025/08/25

In this episode of Precision Medicine Made Simple, we’re joined by Dr. Rich Joseph, a physician with a rare blend of expertise as both a strength and conditioning specialist and a competitive athlete. Dr. Joseph is the founder of VIM Medicine and the Board Chair of Vital Connections. He’s also a faculty member at Harvard Medical School and Brigham and Women’s Hospital, where he focuses on preventive medicine.Dr. Joseph’s unique approach integrates performance medicine, which he defines as the

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01:00:17

7 Paradigm Shifts That Will Rewrite Medicine

Precision Medicine Made Simple ·

2025/08/11

Most of today’s healthcare still treats problems after they happen. Dr. Leroy Hood thinks that needs to change. In this episode of Precision Medicine Made Simple, he explains how genomics, regular health tracking, and AI can shift the focus to preventing disease before it starts. Dr. Hood is one of the scientists who helped build the automated DNA sequencer that powered the Human Genome Project. He also founded the Institute for Systems Biology. He has worked across research, government, and

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57:48

The Osteopathic Doctor Who Maps Your Genetics, Mental...

Precision Medicine Made Simple ·

2025/07/28

What does it really take to solve the medical mysteries most doctors dismiss? In this episode of Precision Medicine Made Simple, we sit down with Dr. Hengameh Monsef, DO, an internal medicine physician trained in high-acuity care, now reinventing how we treat chronic and complex illness through concierge precision medicine at Ascending Medicine. She shares her journey from Iran to the U.S., from frustrated hospitalist to data-powered detective. We dive into how whole genome sequencing,

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01:03:51

The Hardest Part of Longevity Medicine According to...

Precision Medicine Made Simple ·

2025/07/15

What if your doctor could predict what will kill you—before it ever becomes a problem? In this episode of Precision Medicine Made Simple, we dive into the evolving landscape of longevity medicine and health AI with Dr. Hillary Lin, Stanford-trained internist, former oncologist, and co-founder of CareCore—a platform empowering wellness creators and brands to offer doctor-supervised, data-driven care. Dr. Lin shares her personal journey from frustration with traditional medicine to building one of the

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53:19

Ep. 25: The Side of Personalized Healthcare No One...

Precision Medicine Made Simple ·

2025/06/30

In this episode of Precision Medicine Made Simple, hosts Dr. William Stanford and Taylor Cu sit down with Dr. Genise Fraiman, founder of Ascending Medicine and a trailblazer in concierge care. With over two decades of experience—from co-founding one of Cedars-Sinai’s top hospitalist groups to mentoring young physicians—Dr. Fraiman shares her personal and professional evolution toward a more human, proactive approach to medicine.Together, they unpack the pressures of traditional practice, the

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53:29

Ep. 24: This Ex-Surgeon Is Reprogramming Aging with...

Precision Medicine Made Simple ·

2025/06/16

We’re living in the age of health data overload—but how do you turn all those insights into real-life transformation? This episode of Precision Medicine Made Simple features Dr. Daniel Stickler, former vascular surgeon turned systems medicine pioneer, who’s leading the charge in longevity, AI-powered diagnostics, and cutting-edge clinical tools.In this candid conversation with hosts Dr. Stanford and Taylor, Dr. Stickler opens up about the moment he walked away from surgery for good—and how it led to

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01:16:33

Ep. 23 - The Former ER Doctor Challenging How We...

Precision Medicine Made Simple ·

2025/06/02

The Former ER Doctor Challenging How We Practice Medicine w/Dr. Sukhjit "Sarge" TakharPrimary-MD.comEmail: drtakhar@primary-md.comTakeawaysDr. Takhar emphasizes the importance of understanding the patient as a person.Concierge medicine allows for more personalized and attentive care.The healthcare system often limits the time doctors can spend with patients.AI can assist in healthcare but cannot replace the human connection.Precision medicine focuses on individual patient needs rather than

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01:08:53

Ep. 22 - The Doctor Who Says Dialysis Is Preventable...

Precision Medicine Made Simple ·

2025/05/19

In this episode, Dr. David Moskowitz shares how thousands of patients have avoided dialysis through genomic medicine — and why most kidney failure is preventable.We dive deep into ACE genes, repurposed drugs like quinapril and ProGraph, and explore what genomic insights could mean for diseases like Alzheimer's and cancer.Heads up: this one gets detailed with a lot of medical terminology. If you're curious but lost, drop the transcript into ChatGPT — it'll help translate the science.Dr. David

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57:50

Ep. 21 - What Jensen Huang Got Right About the Future...

Precision Medicine Made Simple ·

2025/05/05

In this episode, Dr. Stanford, Lucy Janoyan, and Taylor Cu reflect on key takeaways from the Precision Medicine World Conference — from AI’s role in understanding disease to the future of polygenic risk scores. They discuss the challenges of data validity, patient privacy, and the evolving role of patients and providers in a tech-driven healthcare landscape, including a highlight from NVIDIA CEO Jensen Huang on how AI is set to reshape the future of medicine.TakeawaysThe conversation around

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02:17

We Want To Hear From You For Season 2

Precision Medicine Made Simple ·

2025/01/13

Podcast Suggestion Survey

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01:24:43

When Genes Collide: A Rare Diagnosis Reveals Complex...

Precision Medicine Made Simple ·

2024/12/30

When Genes Collide: A Rare Diagnosis Reveals Complex Health Interactions with Dr. Philip BretskyFor this episode, Dr. Bretsky shares a remarkable case study that unravels the complex relationship between genes and inflammation. When a patient's mysterious symptoms led to the rare diagnosis of VEXAS syndrome, it revealed an unexpected connection with cardiovascular health, demonstrating how different genetic factors can interact to amplify health risks.Timestamps:3:50 - Introduction to Lp(a) and its

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01:32:46

Beauty Span and Health Span: Where Aesthetics Meets...

Precision Medicine Made Simple ·

2024/12/16

Beauty Span and Health Span: Where Aesthetics Meets Longevity with Dr. Cory GoldbergFor this episode, we dive deep into the intersection of aesthetics and longevity with Dr. Cory Goldberg, a renowned plastic and craniofacial surgeon. Dr. Goldberg bridges the art of aesthetic medicine with the science of precision medicine, sharing groundbreaking insights on how oxidative stress affects both beauty and overall health, and discussing innovative approaches to extending both beauty span and health

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01:02:47

From Flight Medic to Precision Medicine with Dr. Kat...

Precision Medicine Made Simple ·

2024/12/02

From Flight Medic to Precision Medicine with Dr. Kat SchmollyIn this episode, we're joined by Dr. Kat Schmolly. From her adventurous past as an Air Force Flight Medic to her current mission revolutionizing rare disease diagnosis, Dr. Schmolly shares her unique journey into precision medicine. We discuss why bringing personalized care to the frontlines of medicine is crucial, and explore how innovative technologies can transform the future of healthcare.Timestamps:2:58 - How Dr. Schmolly and Dr

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55:22

A Doctor's Mission: How Dr. Scoles Used Genetics to...

Precision Medicine Made Simple ·

2024/11/18

A Doctor's Mission: How Dr. Scoles Used Genetics to Transform Patient Care with Dr. Lyndell ScolesIn this episode, we explore pharmacogenomics, also known as genetic pharmaceutical profiling with Dr. Lyndell Scoles with MDVIP. He’s an early pioneer in using genetic testing to optimize medication choices. With over 30 years of experience in internal medicine, Dr. Scoles shares how genetic pharmaceutical profiling helps determine which medications will work best for each patient based on their unique

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01:14:11

Beyond One-Size-Fits-All: The Science of Drug-Gene...

Precision Medicine Made Simple ·

2024/11/04

Ep. 15 - Beyond One-Size-Fits-All: The Science of Drug-Gene Interactions with Michelle BeckwithThis episode features Michelle "Shelly" Beckwith, a genetics pioneer since the 1990s who worked on the Human Genome Project. She breaks down how pharmacogenetic testing helps optimize medication choices by analyzing how patients' genetic variations affect drug metabolism. The discussion covers testing methods, insurance challenges, and the real-world implementation of pharmacogenetics in clinical practice

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27:05

Genotyping vs. Sequencing: What's the Difference?...

Precision Medicine Made Simple ·

2024/10/21

Genotyping vs. Sequencing: What's the Difference?In this episode, Dr. William Stanford, Dr. Yelena Bykhovskaya and Taylor Cu discuss various genetic testing methods. The conversation compares genotyping, exome sequencing, and whole genome sequencing, with an emphasis on whole genome sequencing, which provides the most comprehensive genetic information.Timestamps:00:03:22 - Discussion begins on what popular genetic testing companies use (genotyping)00:05:09 - Explanation of how genotyping chips

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