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PODCAST

Fractals: Life Science Conversations

The Bracken Group

Insightful, informative, and warmly good-humored, Fractals features life sciences leaders sharing wisdom, career highs and lows, and compelling stories from the intersections of clinical development, health care, and technology. Presented by The Bracken Group.

science life sciences

All Episodes

00:42:38

Beyond the Scan: How Radioligands, Ultrasound, and AI...

Fractals: Life Science Conversations ·

2025/10/01

With more than four decades of experience in oncology, cardiovascular imaging, ultrasound, and radioligand therapy, Dr. François Tranquart has helped shape the field of molecular imaging from both sides of the table—first as an academic physician and researcher, and later as an industry leader driving global clinical development.In this French-language episode of Fractals: Life Science Conversations, François joins host Paul Martinetti to share:Why the transition from academia to industry brought

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00:04:54

From Big Pharma to Biotech: Lessons in...

Fractals: Life Science Conversations ·

2025/09/17

What does it take to lead successful drug development—whether at a global pharma giant or a small biotech start-up?In this episode of SNiPs, Dr. David Krause joins Bracken CEO Dr. Colin Miller to reflect on three decades of experience spanning large organizations like GSK to fast-moving start-ups. From aligning clinical development with medical affairs to serving “many masters” in drug development, patients, regulators, providers, and marketers, Dr. Krause shares insights on how to keep the patient

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00:24:40

Personalized Medicine, Pharma Leadership, and the...

Fractals: Life Science Conversations ·

2025/08/19

With more than 30 years of experience spanning global pharma, emerging biotech, and the evolving field of personalized medicine, Bracken Senior Partner Dr. David Krause has helped shape the clinical and regulatory landscape across therapeutic areas—from vaccines and anti-infectives to neuropsychiatry and oncology.As a physician, former Chief Medical Officer, and trusted development advisor, David brings a uniquely humanist and interdisciplinary lens to the science and strategy of drug development.In

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00:08:05

Beyond Human Vision: AI’s Role in the Future of...

Fractals: Life Science Conversations ·

2025/07/08

Can AI help radiologists see what humans can’t—and speed up drug development in the process?In this episode of SNiPs, Dr. Ben Larimer joins Bracken CEO Dr. Colin Miller to explore how artificial intelligence and machine learning are redefining what’s possible in molecular imaging. From interpreting complex PET scans to designing radiopharmaceuticals faster than ever, the future of diagnostics is being shaped by intelligent tools.Dr. Larimer shares real-world examples of how AI is already shaping

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00:35:22

Imaging the Invisible: Granzyme B and the Future of...

Fractals: Life Science Conversations ·

2025/06/11

As a scientist, innovator, and CEO of CytoSite BioPharma, Dr. Ben Larimer has reshaped how we think about imaging immune response in cancer. His work on Granzyme B PET imaging is unlocking unprecedented insights into whether—and where—immunotherapies are working inside the body.In this episode of Fractals, Ben joins host Colin Miller to discuss:The origins of Granzyme B imaging and what makes it a uniquely powerful imaging agent.How CytoSite’s imaging agent revealed success in preclinical models—and

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00:24:30

Measuring What Matters: Biomarkers, Imaging, and...

Fractals: Life Science Conversations ·

2025/05/27

With more than two decades of experience at the intersection of biostatistics and biomedical imaging, Bracken Senior Partner Dr. David Raunig has been a driving force in biomarker development, validation, and regulatory strategy. From leading FDA biomarker qualification review teams to co-inventing imaging advancements and setting industry-wide standards through QIBA, David has played a pivotal role in defining how we measure—and trust—biological data in clinical trials.In this episode of Fractals:

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00:05:33

Rapid Readouts: How Imaging Biomarkers Accelerate...

Fractals: Life Science Conversations ·

2025/04/22

In drug development, the right biomarker can mean the difference between success and a missed opportunity. In this episode of SNiPs, Bracken Senior Partner David Raunig, PhD explores how imaging biomarkers—like DXA and the fracture risk score—are being used in new ways to assess efficacy in clinical trials, especially for rare and complex diseases. David breaks down the evolving landscape of FDA qualification, highlighting a flexible path that allows sponsors to leverage novel endpoints without

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00:43:30

Biotech Venture Capital: Bubbles, Booms, & Bursts...

Fractals: Life Science Conversations ·

2025/01/29

Scientist, entrepreneur, and investor—three small words to describe the way Hatch BioFund Managing Partner Dr. Lorenzo Pellegrini has devoted his career to translating the cutting-edge into impactful solutions. From founding six biotech companies to driving investments in industry-shaping firms like Elevation Pharmaceuticals and Anacor, Lorenzo has consistently championed the necessity of fusion between innovation and practicality in the life sciences. In this episode of Fractals: Life Science

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00:04:53

A Wealth of Experience: Biotech M&A with Guest...

Fractals: Life Science Conversations ·

2025/01/08

What does it take to balance bold innovation with prudent decision-making in biotech? Lorenzo Pellegrini, PhD, Managing Partner at Hatch BioFund, shares his perspective and experience on the strategic choices that define success—and survival—in the industry.From securing $20M to $200M in funding, to grappling with the complexities of portfolio diversification, Lorenzo unpacks the critical factors biotech companies must consider. He discusses the nuances of resource allocation, the power of clear

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00:36:44

Reactive to Proactive: Product Development with Guest...

Fractals: Life Science Conversations ·

2024/12/04

With career highlights including the launch of Ivermectin and NuvaRing, along with expertise spanning microbiome therapeutics, M&A, regulatory affairs, and clinical and non-clinical development, it’s no surprise that Bracken Senior Partner Dr. Graham Lumsden is striving to shift our approach to healthcare. Holding a doctorate in veterinary medicine, Graham takes an integrated approach that bridges the various facets of life sciences. He advocates for preventative medicine and strategic partnerships

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00:04:29

Practical to Profitable: Product Development with...

Fractals: Life Science Conversations ·

2024/11/13

In the biopharmaceutical industry, groundbreaking discoveries may start in the lab—but to reach the market, they require more than just great science.In this SNiP, life sciences veteran Dr. Graham Lumsden highlights an essential yet often overlooked step: identifying unmet medical needs before developing a solution. Drawing from decades of experience, Graham shares the value and necessity of a market-first approach, where science and business strategy align to drive commercial success. Especially

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00:24:28

Creating Connectivity: Patient, Marketing, & Tech...

Fractals: Life Science Conversations ·

2024/10/30

One could describe Mary Costello as a world-class expert in international marketing, business initiatives, and leadership, with a background in patient advocacy, global marketing initiatives, and clinical trial solutions—and one would be correct. Her impressive career includes roles such as Head of Site and Investigator Network at Medable, Vice President of Clinic Development & Patient Advocacy at Elligo Health Research, and Vice President/Global Director of Marketing at leading life science

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00:07:52

From Vision to Validation: Life Sciences Marketing...

Fractals: Life Science Conversations ·

2024/10/14

When launching a product or service, it all comes down to one essential question: what problem are you really trying to solve?In this SNiP, global marketing strategist and life science industry expert Mary Costello breaks down the essential steps to uncovering the root causes of a company’s marketing challenges. From the importance of understanding buyer behavior to the consequences of burning through time and money without validating demand, Mary shares the realities of marketing that every life

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00:38:59

Science, Strategy, Success, and Psychedelics with...

Fractals: Life Science Conversations ·

2024/10/02

With expertise in pharmacology, due diligence, strategic planning, peptide-based therapeutics, and beyond, it’s no wonder that Bracken co-founder and Managing Partner Dr. Jim Gilligan is also leading the way in therapeutic psychedelic drug development. With 35+ years of expertise, Jim’s cutting-edge work is reshaping our approach to mental health and chronic pain management. This integrated approach combines clinical insight with scientific innovation, turning psychedelic research into practical,

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00:06:40

Psychedelics: A New Frontier with Guest Jim Gilligan

Fractals: Life Science Conversations ·

2024/09/18

Imagine a world where therapeutic psychedelic drugs aren’t just visionary, but practical, scalable, and scientifically sound. That world is almost here. In this SNiP, Bracken Co-Founder and Managing Partner Jim Gilligan, PhD takes us behind the scenes of his groundbreaking advances in psilocybin treatment. Jim reveals how an integrated approach can turn bold ideas into commercial reality, with insights on regulating psilocin for therapy and advice for bringing revolutionary, patient-focused

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00:28:57

From Medicine to Multimedia with Guest Paul Martinetti

Fractals: Life Science Conversations ·

2024/09/04

Medical doctor, digital software and hardware programmer, and professional trainer—Bracken Senior Partner Paul Martinetti continues to defy a singular career path. Paul exemplifies an integrated approach: leading collaborative efforts to invent, build, and implement innovative solutions, such as an online photo-based acne severity consensus tool and a clinical study t-shirt, setting new industry standards, and leveraging multimedia technology development to support oncology survivors in clinical

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00:04:20

Focus Forward: Technology & Healthcare with Guest...

Fractals: Life Science Conversations ·

2024/08/20

Start your project early, communicate with regulatory bodies often, and begin with the validation in mind—that’s Dr. Paul Martinetti’s starting advice for aspiring life scientists looking to bridge the gap between technology and healthcare. Tune into our latest SNiP, a special segment of Fractals Life Science Conversations, to hear more. Listen now, and stay tuned for the full episode of Fractals, releasing later this month.

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00:03:55

People & Platforms: Data Analytics Necessities with...

Fractals: Life Science Conversations ·

2024/08/07

When you think about “people and platforms”, does “data analytics” come to mind? In this SNiP, our new special recurring segment of Fractals: Life Science Conversations, Bracken Senior Partner Ben Mitchell tells us exactly why data analytics, people, and platforms are the foundations for which life sciences thrives. Tune in to learn more about the importance of adopting an integrated approach to your data analytics; Not only is data essential to business—it's equally fundamental to the life sciences

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00:05:29

After the Deal: Life Science M&A with guest Dawn...

Fractals: Life Science Conversations ·

2024/07/24

It's not just about the deal—it's about what happens next. In this episode of SNiPS, Bracken COO Dawn Flitcraft uncovers the surprising reactions and feelings of life science CEOs after their companies are acquired. Learn how having an integration leader and providing executive support can make all the difference. Listen now to hear how 95% of the time, these transitions lead to success.

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00:05:18

Life Science Marketing Matters with Guest Jeff Sorenson

Fractals: Life Science Conversations ·

2024/07/10

Yunu's co-founder and CEO, Jeff Sorenson, recognizes the pivotal role marketing plays in the life sciences sector, spanning brand communication and customer awareness. By prioritizing investments in streamlined user experience (UX), data-informed sales strategies, and cohesive messaging, the significance of marketing can reach new heights—and your company can reach a global audience. Hear more of Jeff’s insights in conversation with Colin Miller in this SNiP, a special segment of Fractals: Life

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34 results

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