Fractals: Life Science Conversations

00:35:05

Decoding the Real-World Language of Healthcare with...

Fractals: Life Science Conversations ·

2026/09/11

Life sciences doesn’t have a data problem. It has a making-sense-of-the-data problem.In this episode of Fractals: Life Science Conversations, Jo Halliday, CEO and Founder of Talking Medicines, joins host Colin Miller to explore how AI, natural language processing, and real-world signals can help life science organizations better understand what patients and healthcare professionals are actually saying—and turn those insights into better decisions.From the episode:Why unstructured healthcare

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00:31:17

Beyond the Snapshot: Imaging Biology in Motion with...

Fractals: Life Science Conversations ·

2026/08/12

Imaging has traditionally been used to document what (already) happened. What if it could help determine what happens next?On the newest episode of Fractals, Colin Miller is joined by Fidēs Imaging CEO Roughan Sheedy and Head of Women’s Health Beth Fisher to discuss how advanced imaging can support earlier, sharper development decisions. They explore: Why early-phase programs need more than standardized endpoints How imaging biology in motion can uncover previously invisible phenomena

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00:33:36

Beyond Pain Management: A One Medicine Approach to...

Fractals: Life Science Conversations ·

2026/07/08

What happens when human health, animal health, and entrepreneurial drug development intersect?In this episode of Fractals: Life Science Conversations, Bracken CEO Colin Miller is joined by Senior Partners Graham Lumsden, BVM&S, Dip.M., MRCVS, and Jonathan Larkin, PhD, to discuss osteoarthritis innovation, One Medicine, and the collaborative pathways that can move novel therapies forward. Together, they discuss: Why osteoarthritis remains a major unmet need in both human and animal health How

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00:33:43

From Simulation to Scale: Rethinking Pharmaceutical...

Fractals: Life Science Conversations ·

2026/04/07

Pharmaceutical manufacturing still struggles with a fundamental challenge: turning complex science into reliable, scalable, real-world processes.Dr. Michael Choi has spent his career solving exactly that. As Founder of PCTS and a pioneer in tablet coating simulation, Michael has developed tools that bring clarity to one of the most complex—and often misunderstood—steps in drug production. In this episode of Fractals: Life Science Conversations, Michael and host Colin Miller discuss: The hidden

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00:21:36

From Baby Feeding to Better Outcomes: Building...

Fractals: Life Science Conversations ·

2026/02/04

What if maternal care was a proactive partner in your baby’s development, not just stepping in at a point of crisis?On this episode of Fractals, Cory Wyman, Director of Marketing at SimpliFed, joins Colin Miller to unpack how virtual lactation and baby-feeding support can reshape maternal health: clinically, emotionally, and economically.From the episode:Why baby feeding is often the first point of contact in postpartum careHow virtual care creates deeper honesty and stronger provider-patient

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00:29:21

Imaging, Trust, and the Real-World: The Current State...

Fractals: Life Science Conversations ·

2026/01/07

With more than two decades of experience spanning clinical practice, translational research, and global industry leadership, Bracken Senior Partner Dr. Deepak Behera has actively shaped how radiopharmaceuticals are developed, evaluated, and delivered to patients. As President and CEO of Adaptive Research and Senior Partner at Bracken, Deepak is an expert in connecting science, strategy, and real-world execution.In this episode of Fractals: Life Science Conversations, Deepak and host Colin Miller

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00:33:59

Beyond Baby Steps: Transforming Maternal Health with...

Fractals: Life Science Conversations ·

2025/11/19

Mary Hardy, Chief Commercial Officer at SimpliFed, is helping reshape maternal health care with a virtual platform that supports families before birth and well beyond the baby’s first milestones. By combining lactation guidance, postpartum care, maternal mental health screening, and remote monitoring, SimpliFed is setting a new standard for holistic, accessible maternal care.In this episode of Fractals: Life Science Conversations, Mary joins host Colin Miller to explore:How SimpliFed’s virtual care

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00:36:02

Nose to Neurons: The Future of Acute Neuropsychiatric...

Fractals: Life Science Conversations ·

2025/10/29

What if a nasal spray could switch off acute social anxiety in minutes—without systemic side effects?Shawn Singh, CEO of Vistagen, joins Fractals to explain how pherines work: odorless intranasal molecules that tap the olfactory pathway to flip specific brain circuits on and off.Highlights from the episode:How pherines activate the nose → olfactory bulb → targeted brain regions in milliseconds.Why fasadienol could be the first acute pharmacologic option for social anxiety disorder.The practical

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00:42:38

Beyond the Scan: How Radioligands, Ultrasound, and AI...

Fractals: Life Science Conversations ·

2025/10/01

With more than four decades of experience in oncology, cardiovascular imaging, ultrasound, and radioligand therapy, Dr. François Tranquart has helped shape the field of molecular imaging from both sides of the table—first as an academic physician and researcher, and later as an industry leader driving global clinical development.In this French-language episode of Fractals: Life Science Conversations, François joins host Paul Martinetti to share:Why the transition from academia to industry brought

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00:04:54

From Big Pharma to Biotech: Lessons in...

Fractals: Life Science Conversations ·

2025/09/17

What does it take to lead successful drug development—whether at a global pharma giant or a small biotech start-up?In this episode of SNiPs, Dr. David Krause joins Bracken CEO Dr. Colin Miller to reflect on three decades of experience spanning large organizations like GSK to fast-moving start-ups. From aligning clinical development with medical affairs to serving “many masters” in drug development, patients, regulators, providers, and marketers, Dr. Krause shares insights on how to keep the patient

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00:24:40

Personalized Medicine, Pharma Leadership, and the...

Fractals: Life Science Conversations ·

2025/08/19

With more than 30 years of experience spanning global pharma, emerging biotech, and the evolving field of personalized medicine, Bracken Senior Partner Dr. David Krause has helped shape the clinical and regulatory landscape across therapeutic areas—from vaccines and anti-infectives to neuropsychiatry and oncology.As a physician, former Chief Medical Officer, and trusted development advisor, David brings a uniquely humanist and interdisciplinary lens to the science and strategy of drug development.In

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00:08:05

Beyond Human Vision: AI’s Role in the Future of...

Fractals: Life Science Conversations ·

2025/07/08

Can AI help radiologists see what humans can’t—and speed up drug development in the process?In this episode of SNiPs, Dr. Ben Larimer joins Bracken CEO Dr. Colin Miller to explore how artificial intelligence and machine learning are redefining what’s possible in molecular imaging. From interpreting complex PET scans to designing radiopharmaceuticals faster than ever, the future of diagnostics is being shaped by intelligent tools.Dr. Larimer shares real-world examples of how AI is already shaping

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00:35:22

Imaging the Invisible: Granzyme B and the Future of...

Fractals: Life Science Conversations ·

2025/06/11

As a scientist, innovator, and CEO of CytoSite BioPharma, Dr. Ben Larimer has reshaped how we think about imaging immune response in cancer. His work on Granzyme B PET imaging is unlocking unprecedented insights into whether—and where—immunotherapies are working inside the body.In this episode of Fractals, Ben joins host Colin Miller to discuss:The origins of Granzyme B imaging and what makes it a uniquely powerful imaging agent.How CytoSite’s imaging agent revealed success in preclinical models—and

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00:24:30

Measuring What Matters: Biomarkers, Imaging, and...

Fractals: Life Science Conversations ·

2025/05/27

With more than two decades of experience at the intersection of biostatistics and biomedical imaging, Bracken Senior Partner Dr. David Raunig has been a driving force in biomarker development, validation, and regulatory strategy. From leading FDA biomarker qualification review teams to co-inventing imaging advancements and setting industry-wide standards through QIBA, David has played a pivotal role in defining how we measure—and trust—biological data in clinical trials.In this episode of Fractals:

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00:05:33

Rapid Readouts: How Imaging Biomarkers Accelerate...

Fractals: Life Science Conversations ·

2025/04/22

In drug development, the right biomarker can mean the difference between success and a missed opportunity. In this episode of SNiPs, Bracken Senior Partner David Raunig, PhD explores how imaging biomarkers—like DXA and the fracture risk score—are being used in new ways to assess efficacy in clinical trials, especially for rare and complex diseases. David breaks down the evolving landscape of FDA qualification, highlighting a flexible path that allows sponsors to leverage novel endpoints without

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00:43:30

Biotech Venture Capital: Bubbles, Booms, & Bursts...

Fractals: Life Science Conversations ·

2025/01/29

Scientist, entrepreneur, and investor—three small words to describe the way Hatch BioFund Managing Partner Dr. Lorenzo Pellegrini has devoted his career to translating the cutting-edge into impactful solutions. From founding six biotech companies to driving investments in industry-shaping firms like Elevation Pharmaceuticals and Anacor, Lorenzo has consistently championed the necessity of fusion between innovation and practicality in the life sciences. In this episode of Fractals: Life Science

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00:04:53

A Wealth of Experience: Biotech M&A with Guest...

Fractals: Life Science Conversations ·

2025/01/08

What does it take to balance bold innovation with prudent decision-making in biotech? Lorenzo Pellegrini, PhD, Managing Partner at Hatch BioFund, shares his perspective and experience on the strategic choices that define success—and survival—in the industry.From securing $20M to $200M in funding, to grappling with the complexities of portfolio diversification, Lorenzo unpacks the critical factors biotech companies must consider. He discusses the nuances of resource allocation, the power of clear

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00:36:44

Reactive to Proactive: Product Development with Guest...

Fractals: Life Science Conversations ·

2024/12/04

With career highlights including the launch of Ivermectin and NuvaRing, along with expertise spanning microbiome therapeutics, M&A, regulatory affairs, and clinical and non-clinical development, it’s no surprise that Bracken Senior Partner Dr. Graham Lumsden is striving to shift our approach to healthcare. Holding a doctorate in veterinary medicine, Graham takes an integrated approach that bridges the various facets of life sciences. He advocates for preventative medicine and strategic partnerships

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00:04:29

Practical to Profitable: Product Development with...

Fractals: Life Science Conversations ·

2024/11/13

In the biopharmaceutical industry, groundbreaking discoveries may start in the lab—but to reach the market, they require more than just great science.In this SNiP, life sciences veteran Dr. Graham Lumsden highlights an essential yet often overlooked step: identifying unmet medical needs before developing a solution. Drawing from decades of experience, Graham shares the value and necessity of a market-first approach, where science and business strategy align to drive commercial success. Especially

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00:24:28

Creating Connectivity: Patient, Marketing, & Tech...

Fractals: Life Science Conversations ·

2024/10/30

One could describe Mary Costello as a world-class expert in international marketing, business initiatives, and leadership, with a background in patient advocacy, global marketing initiatives, and clinical trial solutions—and one would be correct. Her impressive career includes roles such as Head of Site and Investigator Network at Medable, Vice President of Clinic Development & Patient Advocacy at Elligo Health Research, and Vice President/Global Director of Marketing at leading life science

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