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PODCAST

The Neuron: AI Explained

The Neuron is a daily newsletter with 700,000+ readers that covers the latest AI developments, trends and research; this is our podcast, hosted by Grant Harvey and Corey Noles. We aim to create digestible, informative and authoritative takes on AI that get you up to speed and help you become an authority in your own circles. Available Wednesdays and Sundays on all podcasting platforms and YouTube. Subscribe to our newsletter: https://www.theneurondaily.com/subscribe

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All Episodes

00:56:44

Can AI Help Cure Genetic Disease?

The Neuron: AI Explained ·

2026/10/08

Corey and Grant sit down with Mammoth Biosciences co-founder and CEO Dr. Trevor Martin to explain how CRISPR is moving from a laboratory tool toward one-time medicines. Trevor breaks down how Mammoth searches massive biological datasets for new CRISPR systems, why AI is useful but still constrained by missing clinical data, and what it would take to build a feedback loop between AI models, wet labs, and human trials. The conversation also covers personalized medicine, the economics of one-time

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00:56:54

BONUS: GPT-6 Sol vs Claude Opus 5.5 LIVE: Which AI...

The Neuron: AI Explained ·

2026/10/02

GPT-6 Sol, GPT-6 Luna, AND Claude Opus 5.5 all just dropped. So which model should you actually use?Join Grant Harvey and Corey Noles from The Neuron LIVE today as we put the newest models from OpenAI and Anthropic head-to-head.OpenAI says GPT-6 Sol makes roughly half as many mistakes as GPT-5.6 Sol, bringing Astra-level reliability to a much cheaper model, while GPT-6 Luna is designed for fast, high-volume work like summarization, extraction, and quick questions. OpenAI is also dramatically cutting

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00:58:33

How Hume AI Is Teaching Voice Systems to Understand...

The Neuron: AI Explained ·

2026/09/30

AI voices can already sound startlingly human. The harder problem is whether they actually understand how humans speak.Andrew Ettinger, CEO of Hume AI, joins Corey Noles and Grant Harvey to explain why voice AI still has a “listening problem.” A transcript can capture the words someone says while stripping away tone, hesitation, frustration, background noise, dialect, speaker identity, and the other signals that shape what those words actually mean.The conversation explores how Hume evaluates voice

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01:19:51

BONUS: OpenClaw 2.0 with Chief Architect Vincent Koc

The Neuron: AI Explained ·

2026/09/25

OpenClaw 2.0 just landed, and we’re going straight to the person helping build it. 🦞This week on The Neuron LIVE, Vincent Koc, Chief Architect of OpenClaw, joins us for a hands-on look at the biggest OpenClaw update yet.Vincent will demo OpenClaw 2.0, break down what’s new, and show how OpenClaw is evolving from an open-source personal AI assistant into a broader agentic computing platform.We’ll cover:🦞 OpenClaw 2.0 and the biggest changes🖥️ The new OpenClaw experience and easier setup🤖 Running

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00:39:50

Inside CoreWeave’s AI Infrastructure With Chen Goldberg

The Neuron: AI Explained ·

2026/09/23

AI infrastructure used to be the part developers were supposed to forget about. What happens when the infrastructure itself starts determining what AI can doCorey Noles sits down with Chen Goldberg, Executive Vice President, Product & Engineering at CoreWeave, to unpack the systems underneath the next wave of AI. Using CoreWeave’s newly announced multi-rack NVIDIA Vera Rubin NVL72 deployment as a jumping-off point, Chen explains why modern AI infrastructure is no longer just a question of how

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01:58:15

BONUS: A Beginner’s Guide to GitHub, LIVE with...

The Neuron: AI Explained ·

2026/09/18

UPDATE: Blog version here https://theneuron.ai/explainer-articles/github-for-beginners-how-to-use-it-with-ai-coding-agents/GitHub can feel intimidating if you didn’t come up as a developer, especially now that AI coding agents can build software before you’ve learned what a repo, branch, or pull request even is.That’s why The Neuron is going LIVE with Cassidy Williams from GitHub for a beginner-friendly walkthrough of how GitHub actually works.📅 Thursday, September 10 ⏰ 12 PM CT / 10 AM PT / 1 PM

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01:05:12

GPT-6 Astra One-Shot Demos

The Neuron: AI Explained ·

2026/09/16

Corey and Grant put GPT-6 Astra through six identical one-shot build tests to see what it can create with almost no follow-up instruction. The episode covers an interactive black hole lab, a Blender scene, a physics game, a photo-to-sci-fi-world reconstruction, a mechanical sound diagnostic prototype, and the latest version of Cat Doom. The biggest through-line is how much capability now comes out of a single prompt, while the remaining weaknesses show up in taste, UI restraint, game balancing, and

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01:35:28

BONUS: Apple’s AI Era Starts Now? Meta’s Free AI...

The Neuron: AI Explained ·

2026/09/11

We’re going LIVE after Apple’s biggest event of the year to break down John Ternus’s first major keynote as CEO and the big question: Is Apple finally entering its AI era?We’ll unpack what Apple revealed around Siri, Apple Intelligence, and its broader AI strategy, plus what feels different under Ternus.Then, we’re breaking down a packed day of AI news:🍎 Apple’s AI era: What the announcements tell us about Apple’s AI strategy.🧮 OpenAI’s $1M math fight: OpenAI says a massive AI effort made progress

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01:34:40

OpenAI Astra, Local AI, and the Hardware Race

The Neuron: AI Explained ·

2026/09/09

What happens when AI models get powerful enough that the bottleneck stops being the model, and starts becoming the computer, the power grid, or the safeguards around it?Corey Noles and Grant Harvey break down a packed week in AI, starting with OpenAI’s expected Astra model and the controversy around recurrent-depth reasoning, chain-of-thought monitoring, and critical cybersecurity capabilities. They also dig into Google’s Gemini 3.8 Flash and Flash Cyber, and why benchmark charts increasingly matter

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01:00:02

BONUS: Claude Fable 5.1 LIVE: Testing Anthropic’s New...

The Neuron: AI Explained ·

2026/09/04

Anthropic just released Claude Fable 5.1, its newest frontier model for long-running coding, research, and agentic work.So naturally, we’re putting it to the test LIVE. 🤖Early testing suggests Fable 5.1 is faster, easier to work with, and capable of handling massive coding projects, long-form writing, and autonomous agent tasks more efficiently. Every even found that it used less than half as many tokens as Opus 5 in one internal test.But it has some quirks too. It can blow past word counts, create

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00:54:50

Where Does AI Agent Security Actually Live?

The Neuron: AI Explained ·

2026/08/28

AI companies spend enormous effort making models safer, but the model tested in the lab isn't necessarily the system a company eventually deploys. Alice CEO and co-founder Noam Schwartz joins Corey and Grant to explain why prompts, tools, memory, permissions, data, and agent-to-agent interactions create an entirely new security surface. They dig into the growing “trust gap” around enterprise AI, why prompt injection may become a permanent cat-and-mouse game, what open-weight models change for

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01:51:32

BONUS: AI Tool Roundup: What’s Actually Worth Trying?

The Neuron: AI Explained ·

2026/08/21

AI tools are shipping faster than most normal humans can figure out what half of them actually do.So Thursday, August 20 at 10 AM PT / 1 PM ET, we’re going LIVE to translate this week’s biggest AI launches into plain English. 😸The goal: understand what these tools actually are, who they’re for, what’s useful vs. hype, and which ones are worth trying.No three developers yelling model benchmarks at each other for an hour. Instead, we’re covering:🤖 Qwen 3.8: What a powerful open model is, why you

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00:45:53

This AI model will run the economy in 2030 w/...

The Neuron: AI Explained ·

2026/08/19

AI can write code, summarize documents, and hold a conversation. But it still struggles with the structured data businesses rely on to predict churn, fraud, demand, pricing, and risk. Alexandre Pasquiou explains why language models flatten the relationships inside spreadsheets, how tabular foundation models learn from rows and columns, and why Neuralk believes one general model could replace hundreds of custom predictive systems. The conversation also covers Seldon, AI agents, enterprise adoption,

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00:58:52

BONUS: Learn Video Prompting for TOTAL Beginners w/...

The Neuron: AI Explained ·

2026/08/14

Want to make better AI videos but have absolutely no idea what you’re doing?Perfect. Neither did most of us at first. 😹Join The Neuron LIVE this Thursday at 10 AM PT for a total beginner’s guide to AI video generation and video prompting, featuring the team behind the newly announced LTX-2.5.We’re going hands-on with the new model while learning the fundamentals of actually prompting video models effectively.What we’ll cover:🎬 How video prompting is different from image prompting✍️ How to write

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00:51:17

AI Can Now Write DNA. What Does This Promise, And...

The Neuron: AI Explained ·

2026/08/12

AI can now read DNA like language, generate working biological sequences, and help scientists identify disease-related mutations. Radical Numerics CEO Eric Nguyen explains how genome language models work, why his earlier model Evo helped scientists design CRISPR systems and bacteriophage genomes, and how the company’s newer model, Omnii, combines DNA with RNA, proteins, and other biological signals. The conversation explores personalized medicine, gene therapy, AI-designed biological threats,

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01:59:30

BONUS: How to Use AI Agents for Total Beginners: A...

The Neuron: AI Explained ·

2026/08/07

This is the #1 request we get every week: how to actually use agents to save time in your business.We’re bringing in James McAulay, founder of The Agent Accelerator, for a practical crash course on what AI agents are, how they work, and how beginners can start using them to get real work done.James has spent the past year building at the front lines of the agent economy. After helping ElevenLabs grow from $110M to more than $300M in annual recurring revenue, he launched a fully AI-native business

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00:54:37

AI Agents Are About to Move Off the Cloud. Here’s...

The Neuron: AI Explained ·

2026/08/05

What happens when the most capable AI lives in the cloud, but the work you want it to do is too private, expensive, or repetitive to send there every time?Dr. Olena Zhu, Head of AI Solutions & Ecosystem for Intel’s Client Computing Group, joins Corey Noles and Grant Harvey to explain Intel’s vision for hybrid AI: systems that route each task to the right place, whether that is a local model on a PC, a larger model on an edge server, or a frontier model in the cloud.The conversation explores why

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01:08:42

BONUS: How to Publish Your AI-Built App to the App Store

The Neuron: AI Explained ·

2026/07/31

Update! The definitive follow-along walkthrough guide is ready! Check it out here: https://theneuron.ai/explainer-articles/how-to-publish-an-ai-built-iphone-app-to-the-app-store/Building an app with AI is getting easier. Getting it through Apple's doors is still a different adventure.Join Corey Noles and Grant Harvey live on Thursday, July 30 at [10AM PT / 12PM CT / 1PM ET] as they walk through what it actually takes to move an AI-built app from a working prototype into TestFlight and the Apple

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00:23:33

AI Can Build It, But Can AI Ship It?

The Neuron: AI Explained ·

2026/07/29

AI can now help almost anyone turn an idea into a working prototype. But what happens when that vibe-coded experiment needs to become secure, reliable software that real customers can trust—and pay for?Corey Noles and Grant Harvey speak with Deap Ubhi, Global Director of Technology for Startups at AWS, about AWS Startup Advisor, an AI-powered builder assistant designed to bring AWS architecture, security, cost, deployment, and scaling guidance directly into a founder’s workflow.Deap explains why

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02:20:41

BONUS: We Built 15+ Apps With AI. Here’s What...

The Neuron: AI Explained ·

2026/07/24

Join Grant Harvey and Corey Noles live on Thursday, July 23, for a show-and-tell featuring the apps, games, extensions, and delightfully specific tools they’ve built with AI, plus tips to help you build your own without burning through as many tokens.Corey will demo:☕ Bean Counter, which tracks how many cups of coffee he has saved🗂️ Tab Crusher, a Chrome extension for conquering tab overload✍️ Threadline, his editorial operating system for writers🎮 Circle Back, a gamified task-management app🍽️ On

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129 results

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