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PODCAST

Decoding Health

Dr. Urban A. Kiernan

Step into the world of Decoding Health, where Dr. Urban A. Kiernan and renowned experts delve into a myriad of fields, unraveling the complexities of science and its practical applications in our daily health. This show is committed to illuminating topics ranging from personal health and wellness to cutting-edge biopharmaceutical advancements and beyond.Join us each week for an enlightening journey through the realms of science and discover the incredible tools that can enhance your everyday

health & fitness medicine

All Episodes

62:55

Why 93% of Americans are Metabolically Broken with...

Decoding Health ·

2026/04/06

Send us Fan MailIn this episode of the Decoding Health podcast, Dr. Urban A. Kiernan sits down with metabolic health advocate and social media leader Trent Tueller (known as Trentytok) to unravel the mysteries of our metabolism. Trent shares the powerful personal story of losing his father to complications from chronic illness, which ignited his passion for helping others understand the root causes of disease. We dive deep into the science of insulin resistance, the 'supra-additive' effect

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12:43

Wegovy Pill: Easy Just Got Easier

Decoding Health ·

2026/04/02

Send us Fan MailIn this episode of Decoding Health, Dr. Urban A. Kiernan dives deep into the recent FDA approval of the oral version of Wegovy, a GLP-1 receptor agonist that aims to replace weekly injections with a simple pill. We explore the sophisticated SNAC technology required to help amino acid-based drugs survive the harsh environment of the stomach and the hidden trade-offs in clinical timelines that users need to know. Beyond the science, Dr. Kiernan breaks down the escalating legal battles

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66:02

The Truth About Insulin Resistance & The Hunger Code...

Decoding Health ·

2026/03/30

Send us Fan MailCould everything you know about weight loss be wrong? In this episode of Decoding Health, Dr. Urban A. Kiernan sits down with world-renowned kidney specialist and best-selling author Dr. Jason Fung to discuss the science behind weight gain, insulin resistance, and his new book, 'The Hunger Code'.Dr. Fung explains why the "calories in, calories out" model is a failure of logic and how hormones like insulin, cortisol, and GLP-1 act as the body’s metabolic

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11:09

Fasting Insulin: The Lost Biomarker

Decoding Health ·

2026/03/26

Send us Fan MailAre you relying on "normal" blood sugar levels to tell you you're healthy? You might be missing the most important metric of all. In this episode of Decoding Health, Dr. Urban A. Kiernan explains why fasting insulin is the "lost biomarker" that can predict metabolic issues years—or even decades—before they show up on a standard glucose test. In this episode, you’ll learn:- Why the term "pre-diabetes" gives patients a false sense of security.- The

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62:40

Carnivore for Women: Reversing PCOS and Infertility...

Decoding Health ·

2026/03/23

Send us Fan MailBella Ma (The Steak and Butter Gal) joins Decoding Health to reveal the shocking truth about her 6-year journey as a vegan and how it led to debilitating hormonal issues, cystic acne, and chronic anxiety. In this episode, we discuss:- Why Bella lost her period for 6 years and how she got it back in 3 months.- The 'brainwashing' she experienced in the plant-based community.- Her transition to the carnivore diet and why she ate 2 sticks of butter daily.- The connection

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13:46

Akkermansia: The Newest Metabolic Health Craze

Decoding Health ·

2026/03/19

Send us Fan MailAre you caught up in the GLP-1 weight loss craze? Before you look into injections, you need to hear about Akkermansia Muciniphila. In this episode of Decoding Health, Dr. Urban A. Kiernan breaks down the science of this "miracle" bacterium. We explore how it helps with gut healing, blood sugar control, and weight loss, but more importantly, we discuss why most supplements on the market might be failing you. Topics covered:- Why Dr. Urban A. Kiernan is skeptical of the

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64:56

Quantum Human Performance: Rebuilding Your Brain,...

Decoding Health ·

2026/03/16

Send a textIn this deeply moving and scientific episode of Decoding Health, Dr. Urban A. Kiernan interviews Alexander Pujol, founder of Quantum Human Performance. Alex opens up about his 24-year career as a Physician Assistant and the "perfect storm" that led to a mental health crisis and a suicide attempt in 2022. He shares how he rebuilt his life using the same holistic and quantum strategies he now uses to train elite athletes.In this episode, we cover:- The physiological impact of

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14:36

Glyphosate, GMOs & Superweeds: Is Our Food System...

Decoding Health ·

2026/03/12

Send a text In this timely episode of Decoding Health, Dr. Urban breaks down one of the most controversial topics in modern agriculture: glyphosate, GMOs, and the growing concern over long-term cancer risk. With renewed policy discussions under HHS and RFK’s leadership, the conversation explores how genetically modified crops were designed to increase yield—but how widespread glyphosate use has created unintended consequences, including “superweeds” resistant to herbicides. What started...

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53:24

Telemedicine, GLP-1 Shortcuts, and Sustainable...

Decoding Health ·

2026/03/09

Send a textIn this Decoding Health episode, Dr. Urban A. Kiernan sits down with Dr. Nick Nwabueze—known as “The Fittest Doc”—to unpack the real origin behind the name and the deeper philosophy it represents: becoming the fittest version of yourself through daily actions, behaviors, and sustainable habits. Dr. Nick shares his path from mechanical engineering at Michigan State to medical school at Ohio State, and how a pivotal CrossFit experience during training reframed his understanding of fitness,

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11:29

South Park Was Right: Flip The Food Pyramid (But...

Decoding Health ·

2026/03/05

Send a textIn this episode of Decoding Health, Dr. Urban reacts to a viral cultural moment—South Park’s “flip the food pyramid” satire—and uses it to unpack what a real shift in U.S. nutrition guidance would mean for metabolic health. He breaks down the core changes being celebrated: higher prioritization of protein and fat, reduced emphasis on grains and refined carbohydrates, and updated protein targets (including the renewed acceptance of red meat as a viable protein source). The takeaway is

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64:25

How To Build Confident Kids Without The “Pro Athlete”...

Decoding Health ·

2026/03/02

Send a textIn this Decoding Health episode, Dr. Urban A. Kiernan sits down with Alex Weisman, founder of Quantum Human Performance and a KidStrong owner/operator in the Phoenix market, for a wide-ranging conversation on what children’s health actually requires in 2026. They break down KidStrong’s science-based model built around physical development, cognitive training, and character-building, and why it matters in an era of screens, shrinking PE programs, and rising metabolic risk in kids. Alex

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20:24

The Rise of Insulin Resistance

Decoding Health ·

2026/02/26

Send a textIn this Decoding Health hot-seat episode, Dr. Urban A. Kiernan breaks down the real “upstream” story behind type 2 diabetes—and why the most dangerous phase often happens long before your labs ever flag you as “diabetic.” He explains the progression from insulin resistance → so-called “pre-diabetes” → type 2 diabetes, why he considers the “pre-diabetes” label a false comfort zone, and how modern life factors like endocrine disruptors, chronic stress, diet, and low movement quietly stack

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46:18

Skinny Fat Is Real: How To Read A DEXA Scan For True...

Decoding Health ·

2026/02/23

Send a textIn this Decoding Health episode, Dr. Urban A. Kiernan sits down with returning guest Dr. Micah Olson (pediatric endocrinologist turned longevity physician and founder of Valley HealthSpan in Phoenix) to unpack what DEXA scans can actually reveal about true health—not just aesthetics. They break down how DEXA goes beyond bone density to deliver actionable body-composition metrics like lean mass, body fat percentage, and—most importantly—visceral adipose tissue, the internal fat linked to

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17:22

Not All Body Fat Is The Same

Decoding Health ·

2026/02/19

Send a textIn this episode of Decoding Health, Dr. Urban breaks down one of the most misunderstood—and most dangerous—topics in modern health: visceral fat. While most people focus on the fat they can see or pinch, Dr. Urban explains why peripheral fat is largely aesthetic, while visceral (also called ectopic) fat is metabolically toxic. This internal fat infiltrates organs like the liver, pancreas, and muscle tissue, impairing function at both the organ and cellular level. The discussion clarifies

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63:06

From Big T To Fitness Phenom with Tony Drake

Decoding Health ·

2026/02/16

Send a textIn this episode of Decoding Health, Dr. Urban A. Kiernan sits down with Tony Drake—lifestyle transformation coach, former WWF wrestler, and the man who lost 130 pounds and dropped from ~40% body fat to ~6%—to unpack what actually drives sustainable fat loss and lasting metabolic health. Tony shares the pivotal mindset shift that forced “Big T” to die, how consistent training and nutrition rewired his identity, and how that transformation opened doors to wrestling with WWE/WWF and touring

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11:13

Urolithin A Explained: The Mitochondrial Upgrade...

Decoding Health ·

2026/02/12

Send a textIn this episode of the Decoding Health, Dr. Urban Kiernan breaks down the science behind Urolithin A, a gut-derived compound gaining attention for its role in mitochondrial health, muscle performance, and metabolic function.The conversation explains what Urolithin A actually is (and what it isn’t), how it’s produced through the gut microbiome, and why it’s fundamentally different from peptides. Dr. Urban walks through the concept of mitophagy—the cellular process that clears damaged

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59:41

Insulin Resistance & Prediabetes: Metabolic Reset...

Decoding Health ·

2026/02/09

Send us a textDr. Kaitlin Castillo pulls back the curtain on why so many people can look healthy on the outside while quietly living in a metabolic “danger zone” underneath the surface. Using real-world clinical context, she breaks down what processed, packaged eating does to blood sugar regulation, why insulin resistance can progress for years before patients are clearly warned, and what “good doctor” communication should look like when labs start trending in the wrong direction.The conversation

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13:06

GHK-Cu Explained: The Science Behind Copper Peptides,...

Decoding Health ·

2026/02/05

Send us a textGHK-Cu (copper peptide) has surged in popularity across regenerative medicine, aesthetics, and biohacking—but what does the science actually say? In this episode of Decoding Health, Dr. Urban breaks down the real physiology behind GHK-Cu, a naturally occurring copper-binding tripeptide composed of glycine, histidine, and lysine. You’ll learn how this peptide supports wound healing, collagen remodeling, tissue regeneration, and why it’s increasingly used for skin rejuvenation and hair

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65:33

Metabolic Syndrome: The Real Heart Attack Warning...

Decoding Health ·

2026/02/02

Send us a textRonald M. Krauss joins the show for a practical, myth-busting deep dive into cardiometabolic risk, lipidology, and why the LDL conversation is often framed in the wrong direction. Building on his long-standing advisory-level relationship with Dr. Urban and his “disruptor” approach to improving outcomes, Dr. Krauss clarifies the critical difference between LDL and LDL cholesterol, uses a memorable “bus cholesterol” analogy to explain particle number vs. cholesterol content, and ties the

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11:58

Why Natural GLP-1 Disappears So Fast: DPP-4,...

Decoding Health ·

2026/01/29

Send us a textGLP-1 is a gut-derived hormone designed to signal the pancreas to produce insulin—but in its natural form, it’s notoriously short-lived. In this Decoding Health segment, we break down why endogenous GLP-1 has an ultra-short half-life (about three minutes), and how the enzyme DPP-4 rapidly “clips” incretin hormones by targeting specific amino acids near the N-terminus—effectively destroying the signal before it can last.You’ll learn how GLP-1 receptor agonist drugs were engineered to

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