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PODCAST

The Incubator

Ben Courchia & Daphna Yasova Barbeau

A weekly discussion about new evidence in neonatal care and the fascinating individuals who make this progress possible. Hosted by Dr. Ben Courchia and Dr. Daphna Yasova Barbeau.

health & fitness medicine

All Episodes

88:53

#396 - 📑 Journal Club - The Complete Episode from...

The Incubator ·

2026/02/14

Send a text How much oxygen is enough when resuscitating extremely preterm infants? This week on The Incubator Podcast, Ben and Daphna explore the TORPIDO 30/60 trial comparing 60% versus 30% FiO2 at birth. While primary outcomes were similar, babies in the 60% group needed fewer chest compressions and less epinephrine—a signal worth discussing. They examine an Indian non-inferiority study on surfactant thresholds (40% vs 30% FiO2), where waiting until 40% meant significantly fewer intubation...

en-us

24:31

#396 - [Neo News] - 📌 Does Immigration Enforcement...

The Incubator ·

2026/02/13

Send a text In this episode of Neo News, the team examines the intersection of immigration policy and neonatal care. We review a recent op-ed discussing the "chilling effect" of immigration enforcement on families seeking care in "sensitive locations" like hospitals. The discussion highlights a harrowing report from The 19th about a family detained by ICE while en route to the NICU, sparking a conversation on how fear impacts parental presence and follow-up adherence. The hosts explore the Pr...

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22:57

#396 - [Journal Club] - 📌 Cooling Late Preterms:...

The Incubator ·

2026/02/12

Send a text In this segment, Ben and Daphna review a retrospective study from the Hospital for Sick Children comparing outcomes of therapeutic hypothermia in late preterm (34-35 weeks) versus early term (36-37 weeks) infants. They discuss the significantly higher rates of mortality, hemodynamic instability, and hypoglycemia found in the younger cohort, known as "Group 1". The hosts explore the implications of using MRI scoring systems like the Weeke score for preterm brains and debate the eth...

en-us

17:49

#396 - [Journal Club] - 📌 The 6-Fold Risk of NEC in...

The Incubator ·

2026/02/11

Send a text In this episode of Journal Club, Ben and Daphna review a prospective cohort study from the Journal of Perinatology that examines the care of neonates following in-utero growth restriction. The hosts unpack the critical distinction between Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA), highlighting how the "decay of information" in the NICU can lead clinicians to overlook early risk factors as babies grow. They discuss the study’s alarming findings regarding th...

en-us

15:32

#396 - [Journal Club] - 📌 Surfactant Thresholds: Is...

The Incubator ·

2026/02/10

Send a text In this episode of Journal Club, Ben and Daphna review a non-inferiority trial from the European Journal of Pediatrics exploring surfactant administration thresholds in preterm neonates. The study, conducted in India, compares a 30% versus 40% FiO2 threshold for babies 26-32 weeks gestational age. The hosts break down the counterintuitive findings regarding respiratory support duration in younger subgroups and discuss the broader implications of using rigid FiO2 heuristics versus ...

en-us

21:11

#396 - [Journal Club] - 📌 TORPIDO 30/60: Is Higher...

The Incubator ·

2026/02/09

Send us a text In this episode of The Incubator, Ben and Daphna return from the Delphi Conference to dive back into Journal Club. They review the highly anticipated TORPIDO 30/60 trial published in JAMA, comparing initial oxygen concentrations of 30% versus 60% for preterm resuscitation. The hosts discuss the primary outcomes of survival and brain injury, while highlighting intriguing secondary findings regarding chest compressions and epinephrine use in the delivery room. They also share exc...

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65:30

#395 - [DELPHI PANEL] - How is Artificial...

The Incubator ·

2026/01/29

Send us a text This recording captures the AI panel discussion from the 2026 Delphi Neonatal Innovation Conference, held live on Monday afternoon. Dr. Jim Barry (University of Colorado), Dr. Thao Ho (UCSF), Lindsey Knake (University of Iowa), Selva Selvaraj (Nicklaus Children's Health System), and Dr. Ryan McAdams (University of Wisconsin-Madison) discuss where AI stands in the NICU today. The panelists cover predictive models for sepsis and NEC, AI documentation tools, and the gap between re...

en-us

25:06

#394 - The Pxxs: Pampers Creates the World's Smallest...

The Incubator ·

2026/01/18

Send us a text What if the smallest patients finally had a diaper designed just for them? For years, NICUs have struggled to find appropriately sized diapers for extremely premature infants, often resorting to makeshift solutions that compromised skin integrity and care quality. That changes now. In this breaking news episode, Ben sits down with Harry McCusker, Director of Research and Development for North America Pampers Diapers, to discuss the groundbreaking launch of the Pxxs diaper—the w...

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90:24

#393 - 📑 Journal Club - The Complete Episode from...

The Incubator ·

2026/01/17

Send us a text Could a simple blood test help identify chronic pulmonary hypertension when echo access is limited? This week on The Incubator Podcast, Ben and Daphna explore this question and others relevant to daily NICU practice. A Toronto study examines NT-proBNP as a practical diagnostic tool in extremely preterm infants. They also examine a puzzling finding from Italy and Belgium: despite near-universal antibiotic use in neonates with HIE undergoing cooling, actual culture-positive sep...

en-us

22:30

#393 - [Neo News] - 📌 CDC vs. AAP: What Is the Right...

The Incubator ·

2026/01/16

Send us a text This week on Neo News, we tackle the recent and controversial divergence between CDC and AAP guidelines regarding the birth dose of the Hepatitis B vaccine. With the CDC now recommending a deferred schedule for infants of Hepatitis B-negative mothers, we explore the clinical implications, the risks of vertical transmission, and the challenge of navigating discordant public health advice. We discuss how to handle shared decision-making in an era of waning vaccine confidence and ...

en-us

24:57

#393 - [Journal Club] - 📌 Are We Too Busy? NICU...

The Incubator ·

2026/01/15

Send us a text In this episode of Journal Club, Ben and Daphna review a retrospective cohort study from the Journal of Perinatology examining the association between NICU capacity strain and neonatal outcomes. We discuss how high census and acuity on admission day correlate with increased mortality and morbidity when adjusted for hospital and patient factors. Join us as we explore why being "slammed with admissions" is more than just a badge of honor—it’s a critical safety metric for our pati...

en-us

18:25

#393 - [Journal Club] - 📌 Replacing Sepsis Screens...

The Incubator ·

2026/01/14

Send us a text In this episode of The Incubator Podcast, Ben and Daphna review a pivotal population-based study from Norway examining a new approach to Early-Onset Sepsis (EOS). The hosts discuss whether serial physical examinations can safely replace routine antibiotic prophylaxis in at-risk term and late-preterm infants. With antibiotic exposure often far exceeding sepsis incidence, this study offers compelling data for a "less is more" strategy. Tune in as Ben and Daphna explore the safety...

en-us

22:06

#393 - [Journal Club] - 📌 Antibiotic Use in HIE, A...

The Incubator ·

2026/01/13

Send us a text In this episode of Journal Club, Ben and Daphna dive into a multicenter retrospective study from the European Journal of Pediatrics questioning the necessity of universal empiric antibiotics in neonates undergoing therapeutic hypothermia for HIE. Comparing Italian and Belgian cohorts, the team discusses the reality of a 111 Number Needed to Treat (NNT) for a single case of culture-proven sepsis. From the diagnostic challenges of overlapping clinical markers to the fascinating "...

en-us

22:08

#393 - [Journal Club] - 📌 Can NT-proBNP Guide...

The Incubator ·

2026/01/12

Send us a text In this Journal Club episode of the Incubator Podcast, Ben Courchia and Daphna Yasova-Barbeau review a study from the Journal of Perinatology evaluating NT-proBNP as a diagnostic tool for chronic pulmonary hypertension in extremely preterm infants. The discussion walks through the clinical burden of pulmonary hypertension in babies with bronchopulmonary dysplasia, the limitations of echocardiography, and the appeal of accessible biomarkers. Using data from a SickKids Toronto co...

en-us

90:48

#392 - 📑 Journal Club - The Complete Episode from...

The Incubator ·

2026/01/10

Send us a text This week on The Incubator Podcast, Ben and Daphna review several recent studies in neonatal care. They start with a JAMA trial comparing expectant versus active PDA management in preterm infants, noting a survival signal favoring expectant care and discussing how this fits within current practice. They then review outcomes of 21-week gestation infants from the University of Iowa, focusing on resuscitation strategies and survival at the limits of viability. The conversation co...

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24:46

#392 - [Neo News] - 📌 Beyond the $32 Million Verdict,...

The Incubator ·

2026/01/09

Send us a text In this episode of Neo News, Ben, Daphna, and Eli tackle the complex and emotionally charged landscape of legal liability in the NICU. Following a recent $32 million settlement involving necrotizing enterocolitis (NEC) and cow's milk-based formula, the team debates the future of informed consent for routine nutritional care. They explore how legal precedents may force neonatologists to replace bedside counseling with transactional forms, potentially eroding trust and complicati...

en-us

17:02

#392 - [Journal Club] - 📌 Do Antenatal...

The Incubator ·

2026/01/08

Send us a text In this Journal Club episode, Ben and Daphna review a large national cohort study examining the association between antenatal corticosteroid exposure and survival in extremely preterm infants born between 21 and 24 weeks’ gestation. They discuss biologic plausibility, practice variation, and the challenges of interpreting retrospective data, while focusing on how these findings may inform counseling and shared decision-making at the margins of viability. ---- The Effects of Ant...

en-us

14:57

#392 - [Journal Club] - 📌 Could Longer Caffeine...

The Incubator ·

2026/01/07

Send us a text Ben and Daphna review the ICAF randomized clinical trial evaluating extended caffeine therapy in preterm infants and its impact on intermittent hypoxia through 41 weeks postmenstrual age. They discuss the study design, oximetry outcomes across multiple saturation thresholds, inflammatory biomarkers including TNF-α, and clinically relevant safety signals such as oxygen restart rates, length of stay, and weight gain. The conversation focuses on what intermittent hypoxia may mean ...

en-us

28:22

#392 - [Journal Club] - 📌 Early Outcome Data After...

The Incubator ·

2026/01/06

Send us a text In this Journal Club episode, Ben and Daphna review a salient study from JAMA Network Open examining outcomes of infants born at 21 weeks’ gestation at the University of Iowa. They walk through resuscitation practices, early physiologic challenges, survival trends, and short-term developmental outcomes, while placing the data in the broader context of shifting limits of viability. The discussion highlights both cautious optimism and the many unanswered questions that remain as ...

en-us

21:52

#392 - [Journal Club Shorts] - 📌 Is PDA Treatment...

The Incubator ·

2026/01/05

Send us a text In this Journal Club episode, Ben and Daphna review a major randomized clinical trial published in JAMA comparing expectant management with active pharmacologic treatment of patent ductus arteriosus in preterm infants. They walk through the trial design, inclusion criteria, and outcomes, highlighting the unexpected survival difference favoring expectant management despite similar rates of bronchopulmonary dysplasia. The discussion explores the implications for bedside decision-...

en-us

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