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PODCAST

Fat Science

Dr Emily Cooper

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go (and stay!) away. In each episode, we share little-known facts and personal experiences to dispel misconceptions, reduce stigma, and instill hope. Fat Science is committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical

health & fitness medicine

All Episodes

00:47:20

Breaking Drug News: Combination GLP-1s, Treatment for...

Fat Science ·

2026/10/05

What do new drug reports really mean for your treatment?Explore groundbreaking updates on potential diabetes and weight-loss drugs from Novo Nordisk and Eli Lilly. Dr. Emily Cooper dives into top-line results, explaining what these findings mean for those struggling with metabolic issues.KEY TAKEAWAYSUnderstanding the difference between efficacy estimand and treatment policy estimand.Cagrisema’s potential in aiding weight loss compared to Mounjaro in patients with type 2 diabetes.Semaglutide's

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01:22:55

The Fat Science Origin Story

Fat Science ·

2026/09/28

Have you ever felt that diets don't work for you? Mark Wright, Andrea Taylor, and Dr. Emily Cooper dive deep into the science of metabolism, challenging the myths surrounding diets and weight gain. With personal stories and expert insights, they explore how metabolic function and genetics play vital roles in our health.KEY TAKEAWAYSDiets often don't address underlying metabolic issues.Metabolic syndrome involves multiple health systems and requires comprehensive care.GLP-1 medications have

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00:53:42

Listener Spotlight: Alessio’s Metabolic Wake-Up Call

Fat Science ·

2026/09/21

Can metabolic dysfunction be the cause of anxiety?Join Dr. Emily Cooper, Andrea Taylor, and guest Alessio De Martis as they explore the fascinating intersection of metabolic health, anxiety, and the struggle with traditional diet advice. Learn how under-fueling can exacerbate metabolic issues and what that means for your overall health. KEY TAKEAWAYSAlessio's experience highlights the struggle of self-managing metabolic health in Europe.Under-fueling can worsen metabolic dysfunction, disrupting body

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00:51:31

Back to School Metabolism Tips for the Whole Family

Fat Science ·

2026/09/14

What's the back-to-school metabolism shift all about? The return to a school routine can have surprising impacts on metabolic health. Dr. Emily Cooper explains how sleep, nutrition, and scheduling affect metabolism, and offers practical advice for parents managing these transitions. KEY TAKEAWAYSSleep quality is crucial for kids' and parents' metabolic health.Proper fueling before, during, and after exercise is essential for kids.Maintaining a consistent schedule can help manage stress

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00:47:32

Mailbag: Navigating Menopause and Metabolic Health

Fat Science ·

2026/09/07

Is menopause impacting your weight and health in unexpected ways? In this episode, the hosts tackle an assortment of listener questions about weight loss, metabolic health, and menopause. They delve into the intricacies of medication tolerance, the ethics of unregulated weight loss drugs, and the physiological changes that can affect women during menopause. KEY TAKEAWAYSUnderstanding metabolic and hormonal impacts during menopause is crucial.Unregulated weight loss drugs pose significant risks and

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00:43:27

Top Metabolism Killers Revealed

Fat Science ·

2026/08/31

What are the top causes of metabolic disruption?In this informative episode, Dr. Emily Cooper dives into the factors that quietly sabotage metabolic health. From the intricacies of sleep to the surprising connection between love and metabolism, listeners will learn what enhances or damages their metabolic system.KEY TAKEAWAYSSleep is crucial for metabolic and hormonal balance.Weight cycling severely impacts metabolic health.Underlying stress and emotional wellbeing affect metabolism.NOTABLE

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00:38:33

Mailbag: GLP-1 Injection Reactions

Fat Science ·

2026/08/24

Do you ever wonder how medications like Wegovy and Mounjaro influence your metabolic health? Dr. Emily Cooper, along with Andrea Taylor and Mark Wright, dives into listener questions about maintaining metabolic health when medication coverage is lost, understanding the role of leptin after weight loss, and the effects of medications like Mounjaro. They also explore the injection site reactions and the complex interplay between thyroid, exercise, and inflammation.KEY TAKEAWAYSLoss of medication

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00:38:57

How Wildfire Smoke Affects Metabolism

Fat Science ·

2026/08/17

Is wildfire smoke affecting more than just your lungs?Poor air quality affects not only respiratory health but also metabolic functions. Wildfire smoke can trigger inflammation, oxidative stress, and hormone release, leading to metabolic disturbances.KEY TAKEAWAYSWildfire smoke can impact metabolism, leading to insulin resistance.Stress hormones released during smoke exposure can raise blood sugar levels.Air pollution is linked to increased risk of metabolic syndrome components. NOTABLE

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00:49:15

Inside the GLP-1 Secret Shopper Study

Fat Science ·

2026/08/10

Is it really a good idea to get medical care from online pharmacies posing as clinics?This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor dig into a Yale secret shopper study that tested 49 websites selling GLP-1 medications online. The websites look and market like medical clinics, but the study found that most patients never spoke to a clinician at all before getting a prescription. Dr. Cooper, Mark, and Andrea unpack what real medical care requires, why these platforms skip

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00:46:04

The Truth About Exercise and Metabolism

Fat Science ·

2026/08/03

Does exercise really boost metabolism, or is there a hidden truth?In this episode, Dr. Emily Cooper uncovers the science behind why exercise isn’t just about burning calories. Dive into the fascinating world of myokines, the chemical messengers released by muscles that impact everything from mood to inflammation. Discover why it's not your fault if exercise alone isn't solving your metabolic issues.KEY TAKEAWAYSExercise impacts more than calorie burn; it's a signaling system for the

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00:40:38

Mailbag: Understanding Body Dysmorphia

Fat Science ·

2026/07/27

How does biology affect our perception of body size?Dr. Emily Cooper answers listener questions about body dysmorphia and metabolic dysfunction. Mark and Andrea discuss the challenges with compounded medications and the implications of insurance-driven diet requirements.KEY TAKEAWAYSBody dysmorphia can have biological components related to metabolic dysfunction.Compounded medications may lack the testing and safety guarantees of brand names.Insurance requirements often lack a medical basis and can

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00:50:36

Understanding Metabolism: Latest Scientific Insights

Fat Science ·

2026/07/20

Why is your fat talking to you?In the latest solo episode, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore groundbreaking research into metabolic health. Learn why the scale doesn't always reflect metabolic risk, and discover the science behind fat's active role in the body. KEY TAKEAWAYSMetabolic dysfunction cannot be judged by scale weight alone.Visceral fat is a stronger predictor of heart failure than BMI.Hormonal environments profoundly affect fat storage and health

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00:49:41

Why Carbs Are Good For Your Brain

Fat Science ·

2026/07/13

Is your brain starving for glucose?In this episode, Dr. Emily Cooper explores the critical role of the brain as a metabolic organ and its dependence on glucose and insulin. Listeners will learn why good sleep and a holistic lifestyle are vital for cognitive health.KEY TAKEAWAYSThe brain uses about 20% of your body's energy at rest.Insulin plays a non-fuel role in brain function, supporting neural connections and mood.Sleep is essential for the brain's waste clearance system, the glymphatic

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00:45:12

Mailbag: When Weight Loss Stalls on GLP-1s

Fat Science ·

2026/07/06

Is it normal for GLP-1 medications to become less effective over time?Dr. Emily Cooper discusses listener questions about the nuances of metabolic health and the real reasons behind weight fluctuations and food cravings. With insights into GLP-1 medications, mechanical eating, and more, the episode aims to debunk myths and provide science-based encouragement.KEY TAKEAWAYSTrusting your body's hunger signals can prevent metabolic slowdown.Mechanical eating can help manage sugar cravings and

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00:50:40

Plastic Chemicals in Your Blood and What Actually...

Fat Science ·

2026/06/29

Have you ever wondered why your body holds onto weight despite your best efforts?In this eye-opening episode, Dr. Cooper reveals groundbreaking research showing that 100% of healthy adults carry at least six different plastic-related chemicals in their bodies daily. These endocrine disruptors don't just affect your hormones - they may be stored in your fat tissue and could be a hidden driver of metabolic dysfunction. The good news? New Australian research proves you can dramatically reduce these

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00:47:32

Why Weight Loss Stalls on GLP-1s — Even When You’re...

Fat Science ·

2026/06/22

What happens when GLP-1 medications stop working the way you hoped they would? In this mailbag episode, Dr. Emily Cooper answers listener questions about fasting, insulin levels, PCOS, lipedema, plateaus on Zepbound, and the complicated reality behind metabolic dysfunction. From the dangers of under-fueling to why individualized treatment matters so much, this conversation unpacks the science behind weight resistance with clarity and compassion.Key TakeawaysWhy fasting and restrictive eating may

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00:31:31

Normal Weight Abnormal Metabolism: Why Your Scale...

Fat Science ·

2026/06/15

Could you have metabolic dysfunction even at a normal weight?This episode challenges everything we've been taught about weight and health. Dr. Cooper reveals that up to 25% of normal-weight people have metabolic syndrome, yet they're rarely screened because doctors assume they're healthy based on appearance alone.KEY TAKEAWAYSWeight and metabolic health are not the same thing - you can be metabolically unhealthy at any sizeNormal weight people with metabolic dysfunction are often

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00:51:06

Mailbag: Why GLP-1 Medications Sometimes Stop Working

Fat Science ·

2026/06/08

Have you been told your metabolism is broken and there's nothing you can do about it?This mailbag episode tackles tough questions about medication effectiveness, unexpected side effects, and the complex realities of treating metabolic dysfunction. Dr. Cooper addresses why some people regain weight while still on GLP-1s, explores the connection between hair loss and weight loss medications, and explains why leptin levels can remain stubbornly low even with proper nutrition.KEY TAKEAWAYSWeight

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00:49:12

Why Three Major Obesity Organizations Just Changed...

Fat Science ·

2026/06/01

Ever wonder why you can improve your health but still feel like you're failing because the scale isn't cooperating?Dr. Cooper breaks down groundbreaking new clinical guidelines from three major obesity organizations that are completely reframing what success in obesity treatment actually means. For the first time, these groups are saying quality of life, energy levels, and overall health matter more than the number on the scale.KEY TAKEAWAYSThree major obesity organizations worked

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00:39:56

PCOS is Now PMOS: The Name Change That Changes...

Fat Science ·

2026/05/25

Have you been told you have PCOS but nothing seems to help?In May 2024, after 14 years of global collaboration involving 56 organizations and 22,000 stakeholders, the medical community officially changed PCOS to PMOS - and the reason why reveals everything that's been wrong with how this condition has been understood and treated for decades. Dr. Cooper breaks down why this isn't just a name change, but a complete reframe that puts metabolic dysfunction at the center where it belongs.KEY

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