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PODCAST

Weight and Healthcare

with Ragen Chastain

Examining the intersections of weight science, weight stigma, and healthcare and what evidence, ethics, and lived experience teach us about healthcare and public health best practices for higher-weight people. weightandhealthcare.substack.com

health & fitness medicine

All Episodes

23:38

Study Links Weight Stigma and Inflammation Part 1 -...

Weight and Healthcare ·

2026/02/25

A new study in this vein has come out that looks at the link between weight stigma and inflammation. The study is called The Acute Inflammatory Effects of Weight Stigma: An Experimental Pilot Study and it was published in August, 2025. In part 1 we’ll look at the study authors and the methodology, and in part 2 we’ll look at the results. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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7:13

Healthcare's Weight Loss Best Case Scenario Problem...

Weight and Healthcare ·

2026/02/21

In part 1 we discussed the issues with the decades-long practice of healthcare providers prescribing behavior-based weight loss not based on the evidence (which shows that the vast majority of patients will lose weight short-term and then regain it long-term) but on the belief/hope that every one of their patients will experience the very rare “Best Case Scenario” of significant, sustained weight loss. Today we’re going to talk about how the new GLP-1 weight loss drugs are taking this problem to new

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4:17

Healthcare's Weight Loss Best Case Scenario Problem...

Weight and Healthcare ·

2026/02/18

When it comes to recommending weight loss, healthcare has always had what I call a Best Case Scenario Problem. I think the best way for patients to protect ourselves from this is to understand it so that we can spot it when it’s happening so in Part 1 I’ll examine how this works (in the past and currently) around behavior-based interventions and then in part 2 we’ll look at how GLP-1s are driving an increase in this problem and creating even more harm and what we can do if this problem happens to

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10:47

Novo Nordisk Is In Trouble For Misleading Advertising...

Weight and Healthcare ·

2026/02/14

I’ve had a bunch of requests to write about this so here you go! Novo Nordisk has a long and sordid history of misdeeds, many of which I’ve written about previously. Now they have a new one to add to the list. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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7:46

The Million Pound Challenge Part 2 - The Program

Weight and Healthcare ·

2026/02/07

This is the Weight and Healthcare newsletter! If you like what you are reading, please consider subscribing and/or sharing!In Part 1 we started discussing the “Million Pound Challenge” created by Toby Cosgrove and Dr. Michael Roizen in which they are “challenging” an unknown number of people to collectively lose one million pounds. In part 2 we’ll discuss the program itself. (If you haven’t read part 1, I recommend it to fully understand part 2.) As always I’ll indent the quotes from the website so

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11:27

The Million Pound Challenge Part 1 - The Basics

Weight and Healthcare ·

2026/02/04

Reader Shannon Roosma-Goldstein, MPH, BSN, RN, NPD-BC recently reached out to me because a professional healthcare organization she belongs to had sent her an email encouraging her, as a member, to participate with the organization in the “Million Pound Challenge.”In Part 1 we’ll look at the basic issues with the challenge and who is behind it. In part 2 we’ll look at the details of the program, and in part 3 we’ll talk about what you can do if your workplace announces a program like this, including

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7:14

Three Mistakes Providers Make Recommending Behaviors...

Weight and Healthcare ·

2026/01/31

Behavior-based interventions (sometimes under the auspices of lifestyle medicine) can be evidence-based, health-supporting, and weight-neutral. Unfortunately, when it comes to recommending behavior-based interventions to higher-weight people, there are common mistakes that providers make. We’ll talk about the mistakes and then what patients and providers can do to avoid and/or navigate them. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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17:20

Study Shows Rapid Weight Regain after Ceasing Weight...

Weight and Healthcare ·

2026/01/29

In part 1 we started looking at a study called Weight Regain after cessation of medication for weight management systemic review and meta-analysis by West et al. and in part 2 we looked at the findings. Today I thought it would be helpful to look at how the media is covering this study so we can see how these findings translate. If you haven’t read part 2 (or, at least, the summary) then I recommend starting there. Get full access to Weight and Healthcare at

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18:34

Study Shows Rapid Weight Regain after Ceasing Weight...

Weight and Healthcare ·

2026/01/24

In Part 1 we began discussing Weight Regain after cessation of medication for weight management systemic review and meta-analysis by West et al. Today we’ll discuss the findings. This is a long one so I’ve got a summary and then a deeper dive. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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8:14

Study Shows Rapid Weight Regain after Ceasing Weight...

Weight and Healthcare ·

2026/01/21

I’ve received well over a hundred questions about this new study, all asking roughly the same thing - what does this mean?In Part 1 we’ll talk about the study authors and methodologyPart 2 we’ll talk about the findingsPart 3 we’ll talk about how the media is covering the studyThe study we are looking at is called Weight Regain after cessation of medication for weight management systematic review and meta-analysis by West et al. Get full access to Weight and Healthcare at

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6:15

The Case Against Blaming “Body Habitus” in...

Weight and Healthcare ·

2026/01/17

I was recently advocating for a patient who needed an emergency head CT to rule out some potentially serious complications. (Luckily she was fine and her symptoms had the least concerning diagnosis.) Of course, I have her permission to write about this.A content note, this post is going to include medical weight stigma.After the imaging was done and the report completed the doctor came into the room to tell her that everything on the CT looked “great”.The next day, the results were released to her

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8:21

What's with the Wegovy Pill - Part 3 Trial Findings

Weight and Healthcare ·

2026/01/14

In part 1 we looked at the basics of the newly approved Wegovy pill for weight loss. In part 2 we began looking at the trial that was used for approval (Oral Semaglutide at a Dose of 25 mg in Adults with Overw*ight or Ob*sity.) Today we’ll look at the findings of that trial. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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7:47

What’s with the Wegovy Pill - Part 2

Weight and Healthcare ·

2026/01/10

In Part 1 we looked at what Novo Nordisk’s page said about the new Wegovy Pill for weight loss. Today we’ll look at the trial. Now, Novo didn’t link to the trial (or even mention the name or the authors) on the webpage. They did say twice that it was a 64 week trial. That threw me off for a minute because it was actually written up as a 71 week trial, but we’ll get to that. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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7:34

What's with the Wegovy Pill - Part 1

Weight and Healthcare ·

2026/01/07

Wow did I get a lot of requests to write about this! We’ll start with some basic information today and then break down the actual trial data in the rest of this series. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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5:39

Reader Question - Weight-Neutral Ways to Navigate...

Weight and Healthcare ·

2026/01/03

I received the following question from reader Rebecca:This is my first New Years away from dieting and while I am happier (and healthier, though I know that’s complicated) than ever. Still I am struggling with New Years Resolution season, do you have any tips for making non-diet resolutions that focus on my health?I’m happy to help, you are definitely not alone in trying to navigate this time of year in weight-neutral, non-diet ways! Get full access to Weight and Healthcare at

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8:52

GLP-1s and Knee Osteoarthritis Part 3 - Behavioral...

Weight and Healthcare ·

2025/12/20

In part 1 we talked about a trial of semaglutide for knee osteoarthritis. In part 2 we compared that trial to a trial that used metformin. Today we’re going to talk about research around behavioral (non-pharmacotherapy) weight-neutral interventions. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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16:15

GLP-1s and Knees Osteoarthritis Part 2 - Metformin...

Weight and Healthcare ·

2025/12/17

In part 1 we looked at a study of the effect of semaglutide 2.4mg (Wegovy) on knee osteoarthritis. Today we’ll look at two studies that consider the effect of metformin and compare that with the semaglutide study. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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14:40

GLP-1s and Knee Osteoarthritis - Part 1 Semaglutide

Weight and Healthcare ·

2025/12/13

I've received a number of questions about GLP1s and knee pain/osteoarthritis and in this series we’ll look at what the research says.In part 1 we’ll look at the trial for semaglutide and knee osteoarthritis.In part 2 we’ll look at 2 studies that consider the effects of metformin on knee osteoarthritis.In part 3 we’ll look at a study of a weight-neutral intervention Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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3:47

Quick Guide - Weight-Centric vs Weight-Inclusive...

Weight and Healthcare ·

2025/12/10

I received a question from reader Brit who said “I see you and other people talking and writing about the weight-inclusive and weight-centric (and sometimes weight-neutral and weight-loss paradigm). I think I know what they mean but could you give a quick explanation?I’m happy to Brit, sometimes it’s good to go back to basics! Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

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7:47

Applying Lancet Commission's Concerning Ideas in the...

Weight and Healthcare ·

2025/12/07

In Part 1 we began discussing the article “Implications of a New Ob*sity Definition Among the All of Us Cohort” by Fourman et al. This is a study that took the recommendations of the (heavily financially entangled with the weight loss industry) Lancet Commission around increasing the methods by which “ob*sity” can be “diagnosed” (the massive issues with which I wrote about here,) and applied it to the All of Us population. So what did they find? Get full access to Weight and Healthcare at

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