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MedEvidence Articles

MedEvidence Articles

Welcome to MedEvidence Articles, where we encourage community research and education with weekly articles. Our articles review the history, risks, symptoms, complications, and treatments of diseases with a healthy dose of humor. Visit our website at MedEvidence.com.MedEvidence helps answer the question of “Who can you trust?” for medical information. The MedEvidence platform provides valuable information about many medical issues and the insights of evidence-based medicine. MedEvidence educates

health & fitness medicine

All Episodes

6:47

The Power of Triglyceride Research

MedEvidence Articles ·

2026/02/09

In this week's episode, we explore hypertriglyceridemia: high triglyceride levels in the blood. We look at what triglycerides are, why they might be elevated, and some of the risks and causes of hypertriglyceridemia. We also look at the pivotal role clinical research has and continues to play in controlling this dangerous condition, and give a powerful look at what's being investigated now in the research space. References: Reeskamp LF, Tromp TR, Stroes ES. The next generation of triglyceri...

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6:14

What Does Mouthwash Have to Do with Blood Pressure?

MedEvidence Articles ·

2026/02/02

In this week's episode, we look at the surprising link between mouthwash use and high blood pressure. We explore what mouthwash does, how the bacteria in our mouths are beneficial, and how the products of those bacteria can indirectly affect blood pressure. References: Joshipura K, Muñoz-Torres F, Fernández-Santiago J, Patel RP, Lopez-Candales A. Over-the-counter mouthwash use, nitric oxide and hypertension risk. Blood pressure. 2020 Mar 3;29(2):103-12. https://doi.org/10.1080/08037051.2019.1...

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6:56

DDT, Atopic Dermatitis, and the Consequences of...

MedEvidence Articles ·

2026/01/26

This week we explore atopic dermatitis, oftne called eczema. This skin condition is common, long lasting, and can have serious effects on mental health and relationships. We explore who gets it, how it works in the body, and what treatments are available and on the horizon. References: Fisher G. Presentation speech by professor G. Fischer, member of the staff of professors of the Royal Caroline Institute. Nobel Lectures, Physiology or Medicine 1942-1962. Amsterdam: Elsevier Publishing Company...

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5:36

Clearing the Traffic for Treating Major Depression

MedEvidence Articles ·

2026/01/19

On this week's episode, we show an increased drive into vagus nerve stimulation clinical research. This FDA-approved therapy for major depressive disorder (MDD) is undergoing further trials in an effort to get it approved by big insurance carriers like Medicaid. Hasin DS, Sarvet AL, Meyers JL, et al. Epidemiology of adult DSM-5 major depressive disorder and its specifiers in the United States. JAMA Psychiatry. 2018;75(4):336–346. doi:10.1001/jamapsychiatry.2017.4602Substance Abuse and Menta...

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5:44

Big Clinical Trials on the Horizon for Obesity

MedEvidence Articles ·

2026/01/12

On this week's episode, we look into the calculations being made to develop new obesity treatments. We go into the history, current best practices, body changes, and some possible new solutions in the weight loss field. References: NIDDK. Overweight & Obesity Statistics. U.S. Department of Health and Human Services. https://www.niddk.nih.gov/health-information/health-statistics/overweight-obesity Accessed December 22, 2025.Kuk JL, Rotondi M, Sui X, Blair SN, Ardern CI. Individuals ...

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6:29

Don’t drop the ball on your New Year’s Resolution

MedEvidence Articles ·

2026/01/05

In this week's episode, originally written in 2022, we look at some of the science behind creating and maintaining a successful New Year's resolition. We explore how language, habit, and brain science can all make a difference in makign a better you.

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3:01

Clinical Research Is a Care Option

MedEvidence Articles ·

2025/12/29

In this week's episode, written by guest author Chase Berger, we explore the positive health benefits of clinical research beyond the obvious. We look at how those who can particiapte in clinical research have an alternative method of interacting with healthcare professionals that is quick, consistent, and pateint-oriented. References: Koren, M.J., Geddings, K., (17 November, 2025). Coordinated care through clinical research. On MedEvidence! Truth Behind the Data. [Podcast]. https://www.med...

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4:39

The Science of Gift Giving

MedEvidence Articles ·

2025/12/22

In this week's episode, which revisits a topic from several years ago, we go deep into the brain to explore what happens inside whe nwe give gifts. We explore a few studies which have looked at brain activity during gifting - including during diffrent types of gifting - and explore why giving gifts makes you feel good, connects you with friends, and acts as a prosocial activity. References: Aknin, L. B., Barrington-Leigh, C. P., Dunn, E. W., Helliwell, J. F., Burns, J., Biswas-Diener, R., ....

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4:59

How to Avoid Holiday Heart Syndrome

MedEvidence Articles ·

2025/12/15

In this episode we explore the less cheery side of the holidays: holiday heart syndrome. This syndrome is defined as irregular heartbeats that occur as a result of binge drinking, the type of which is frequently seen around the holidays. We explore the risks, outcomes, mechanics, and treatments of this not-so-happy heart syndrome. References: Jain, A., Yelamanchili, V. S., Brown, K. N., & Goel, A. (2024). Holiday heart syndrome. In StatPearls [Internet]. StatPearls Publishing. https://w...

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7:17

Gout Isn’t Purely a Problem Of Passing Purine

MedEvidence Articles ·

2025/12/08

In this week's episode, we explore the stream of causes that can lead to the painful inflammatory condition gout. We look at the risks, progression, mechanics, and solutions available for this most common inflammatory arthritis. The primary cause of gout is excessive urate in the the blood depositing itself, especially toes. We then look ahead to clinical trials that recently wrapped up or are currently underway and which target the underlying urate in the blood or the immune response to urat...

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4:33

The Placebo Effect Uses Fake Medicine to Get Real...

MedEvidence Articles ·

2025/12/01

In this week's episode, we talk about placebos, which are inert "medications" used to compare with active drugs. We talk about how the use of medications that "do nothing" can provide pain relief, change hormone balance int he body, and lower symptoms across a broad variety of diseases.

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5:57

Thinking Our Way to Better Health

MedEvidence Articles ·

2025/11/24

In this week's episode, we explore some specific, actionable methods for increasing gratitude. These include gratitude journaling, gratitude letters, mental subtraction, and experiantial consumption. We go over what the methods are, how they work, and how expressing gratitude may help mental health.

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4:41

The Goodness of Gratitude

MedEvidence Articles ·

2025/11/17

On this week's episode, we talk about gratitude, and how it can affect mood, positive emotions, and even biological markers of health.

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4:26

Cool Developments in COPD Medicine

MedEvidence Articles ·

2025/11/10

In this week's episode, we talk about how targeting a specific immune cell called an eosinophil may help lower the burden of COPD (chronic obstructive pilmonary disease). We explore the epidemiology, pathophysiology, and treatment options for COPD, including targeting the eosinophil pathway.

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4:52

Improving Flu Vaccine Effectiveness Through Clinical...

MedEvidence Articles ·

2025/11/04

In this episode, we explore the role of adjuvants in vaccines. These addatives help the immune response to a vaccine, making it more effective at stoping infection, complication, hospitalization, and or death. We discuss the need for better vaccines and how adjuvants may be able to help.

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6:41

The Scariest Skeleton Is the One with Osteoporosis

MedEvidence Articles ·

2025/10/28

In this week's episode, we explore osteoporosis, a condition where there's "too little bone in the bone." We look at how bones work normally, and compare that to the risks, pathophysiology, and treatments available to those with osteoporosis. https://medevidence.com/

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5:16

What My Cat Taught Me About Monoclonal Antibodies

MedEvidence Articles ·

2025/10/20

In this week's episode, we explore what monoclonal antibodies are, how they make things happen in the body, and how they can be used in medicine. We discuss how they can be used for identifying cells, delivering drugs to specific cells, or anything in between. Tune in to learn about monoclonal antibodies and hwo they relate to a cat who's a picky eater.

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6:31

What a Cold War Hero Can Teach Us About Chronic Hives

MedEvidence Articles ·

2025/10/13

On this week's episode, we explore the ins and outs of chronic spontaneous urticaria. We discuss the signs, symptoms, complications, and how-it-works of the disease, including how linchpin molecules in the cell like Bruton's tyrosine kinase may be the key to tempering extreme reposnses from a hair-trigger immune system.

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7:12

Untreated MASH Can Be a Driver of Liver Disease

MedEvidence Articles ·

2025/10/02

In this week's episode we review fatty liver disease, called metabolic dysfunction–associated steatotic liver disease (MASLD) and its advanced form, metabolic dysfunction-associated steatohepatitis, or MASH. We look at the prevalence, risks, and complications of this dangerous disease. Then we get into the nuts and bolts of how MASLD and MASH work and some of the treatment options available. References: Allen, A. M., Younossi, Z. M., Diehl, A. M., Charlton, M. R., & Lazarus, J. V. (2024)....

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6:12

Banking on New Eosinophilic Esophagitis (EoE) Treatments

MedEvidence Articles ·

2025/09/29

In today's episode we discuss an immune-mediated disease, eosinophilic esophagitis, or EoE. We review the symptoms, risks, and damage this disease can cause. We also get into what happens inside the body during and what's being done in both standard medicine and clinical research to try to end EoE. References: [1] Muir, A., & Falk, G. W. (2021). Eosinophilic esophagitis: a review. Jama, 326(13), 1310-1318. https://pmc.ncbi.nlm.nih.gov/articles/PMC9045493/ [2] Nurko, S., & Furuta, G...

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