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MedEvidence Articles

MedEvidence Articles

Welcome to MedEvidence Articles, where we encourage community research and education with weekly articles. Our articles review the history, risks, symptoms, complications, and treatments of diseases with a healthy dose of humor. Visit our website at MedEvidence.com.MedEvidence helps answer the question of “Who can you trust?” for medical information. The MedEvidence platform provides valuable information about many medical issues and the insights of evidence-based medicine. MedEvidence educates

health & fitness medicine

All Episodes

4:34

Turning Up the Heat on Weight Loss

MedEvidence Articles ·

2026/04/06

In this week's episode, we explore some of the roles receptors play in the body. We focus on Cannabanoid 1 (CB1) receptors, which regulate appetite and energy expenditure in the body, but can have effects in the brain as well. We look at how receptors can do different things depending on location and that the challenge of medications is in targeting right receptors in the right place. References: Crater GD, Lalonde K, Ravenelle F, Harvey M, Després JP. Effects of CB1R inverse agonist, INV‐2...

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6:10

Sjögren’s Disease is When the Immune System Chases...

MedEvidence Articles ·

2026/03/30

In this week's episode, we talk about Sjögren's disease, a relatively common autoimmune disease. We explore the risks of contracting the disease, who gets it, symptoms, and complications. We also explore how the disease works on a mechanical level inside the body by hijacking the immune system, and finish by looking at what treatment looks like today and what's coming down the clinical trial pipeline tomorrow. References: Patel R, Shahane A. The epidemiology of Sjögren’s syndrome. Clinical ...

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7:56

Gene Editing and Cholesterol: The Road Less Traveled

MedEvidence Articles ·

2026/03/23

In this week's episode we explore gene therapies. We look at what genes are, why mutations can be dangerous, and what methods are being investigated to solve these problems. Then we focus on familial hypercholesterolemia as an example and look at what's being researched today to solve this problem. References: Hoekstra M, Van Eck M. Gene editing for the treatment of hypercholesterolemia. Current Atherosclerosis Reports. 2024 May;26(5):139-46. https://doi.org/verve10.1007/s11883-024-01198-3S...

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6:28

Anemia Disrupts the Body’s Oxygen Supply Chain

MedEvidence Articles ·

2026/03/16

In this week's episode, we explore what happens when the body can't supply enough oxygen to cells. This condition, called anemia, is caused by a drop in red blood cells or the oxygen-carrying hemoglobin inside them. We dive into some of the risks, causes, complications, and treatments associated with anemia. References: Johnson RL, Rubenstein SD. Anemia in the emergency department: evaluation and treatment. Emergency Medicine Practice. 2013 Nov;15(11):1-5. https://pubmed.ncbi.nlm.nih.gov/24...

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7:15

Bipolar Disorder on the Knife’s Edge of Emotion

MedEvidence Articles ·

2026/03/09

In this week's episode, we take a look at bipolar disorder. Bipolar disorder is what happens when out-of-control brain chemicals cut our ability to regulate our mood. The condition results in uncontrollable mood swings that can last for weeks at a time, ranging from impuslive mania to debilitating depression. References: Miller S, Dell'Osso B, Ketter TA. The prevalence and burden of bipolar depression. Journal of affective disorders. 2014 Dec 1;169:S3-11. https://doi.org/10.1016/S0165-0327(...

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4:34

Can Amylin Help Us Navigate Our Way to a Healthy Weight?

MedEvidence Articles ·

2026/03/02

On this week's episode we investigate the molecule amylin, a hormone that also affects the body and brain. Amylin is released in response to eating, and helps us know when we're full. We look at what amylin is, how it works, and how investigational versions of the hormone may help with obesity and weight loss. References: Lange O, Perez L. Traffic prediction with advanced graph neural networks. Google Deepmind Blog. Published September 3, 2020. Accessed February 11, 2026. https://deepmind.g...

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5:46

Eating Carbs Last May Help With Diabetes, No Kidding!

MedEvidence Articles ·

2026/02/23

In this week's episode, we explore the concept of Carbs Last. This is an eating tactic where foods high in fiber and protein are eaten before sugary carbohydrates. A solid history of clinical research studies has shown that this method of eating smooths out spikes in blood glucose and is associated with better outcomes for diabetic patients. Tune in to learn about this fast, free method of helping your body process sugars! References: Willett W, Manson J, Liu S. Glycemic index, glycemic loa...

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7:38

Neurotrophic Keratopathy (NK) Is When the Eye Can’t...

MedEvidence Articles ·

2026/02/16

In this week's episode, we take a closer look at Neurotrophic Keratopathy (NK), a rare nerve condition affecting the eye. We explore how the eye works, the risks of developing NK, possible complications of the disease, and what is actually happening within the eye. We also dive into current treatments, including an new investigational class of medications being researched. References: Dua HS, Said DG, Messmer EM, Rolando M, Benitez-del-Castillo JM, Hossain PN, Shortt AJ, Geerling G, Nub...

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6:47

The Power of Triglyceride Research

MedEvidence Articles ·

2026/02/09

In this week's episode, we explore hypertriglyceridemia: high triglyceride levels in the blood. We look at what triglycerides are, why they might be elevated, and some of the risks and causes of hypertriglyceridemia. We also look at the pivotal role clinical research has and continues to play in controlling this dangerous condition, and give a powerful look at what's being investigated now in the research space. References: Reeskamp LF, Tromp TR, Stroes ES. The next generation of triglyceri...

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6:14

What Does Mouthwash Have to Do with Blood Pressure?

MedEvidence Articles ·

2026/02/02

In this week's episode, we look at the surprising link between mouthwash use and high blood pressure. We explore what mouthwash does, how the bacteria in our mouths are beneficial, and how the products of those bacteria can indirectly affect blood pressure. References: Joshipura K, Muñoz-Torres F, Fernández-Santiago J, Patel RP, Lopez-Candales A. Over-the-counter mouthwash use, nitric oxide and hypertension risk. Blood pressure. 2020 Mar 3;29(2):103-12. https://doi.org/10.1080/08037051.2019.1...

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6:56

DDT, Atopic Dermatitis, and the Consequences of...

MedEvidence Articles ·

2026/01/26

This week we explore atopic dermatitis, oftne called eczema. This skin condition is common, long lasting, and can have serious effects on mental health and relationships. We explore who gets it, how it works in the body, and what treatments are available and on the horizon. References: Fisher G. Presentation speech by professor G. Fischer, member of the staff of professors of the Royal Caroline Institute. Nobel Lectures, Physiology or Medicine 1942-1962. Amsterdam: Elsevier Publishing Company...

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5:36

Clearing the Traffic for Treating Major Depression

MedEvidence Articles ·

2026/01/19

On this week's episode, we show an increased drive into vagus nerve stimulation clinical research. This FDA-approved therapy for major depressive disorder (MDD) is undergoing further trials in an effort to get it approved by big insurance carriers like Medicaid. Hasin DS, Sarvet AL, Meyers JL, et al. Epidemiology of adult DSM-5 major depressive disorder and its specifiers in the United States. JAMA Psychiatry. 2018;75(4):336–346. doi:10.1001/jamapsychiatry.2017.4602Substance Abuse and Menta...

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5:44

Big Clinical Trials on the Horizon for Obesity

MedEvidence Articles ·

2026/01/12

On this week's episode, we look into the calculations being made to develop new obesity treatments. We go into the history, current best practices, body changes, and some possible new solutions in the weight loss field. References: NIDDK. Overweight & Obesity Statistics. U.S. Department of Health and Human Services. https://www.niddk.nih.gov/health-information/health-statistics/overweight-obesity Accessed December 22, 2025.Kuk JL, Rotondi M, Sui X, Blair SN, Ardern CI. Individuals ...

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6:29

Don’t drop the ball on your New Year’s Resolution

MedEvidence Articles ·

2026/01/05

In this week's episode, originally written in 2022, we look at some of the science behind creating and maintaining a successful New Year's resolition. We explore how language, habit, and brain science can all make a difference in makign a better you.

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3:01

Clinical Research Is a Care Option

MedEvidence Articles ·

2025/12/29

In this week's episode, written by guest author Chase Berger, we explore the positive health benefits of clinical research beyond the obvious. We look at how those who can particiapte in clinical research have an alternative method of interacting with healthcare professionals that is quick, consistent, and pateint-oriented. References: Koren, M.J., Geddings, K., (17 November, 2025). Coordinated care through clinical research. On MedEvidence! Truth Behind the Data. [Podcast]. https://www.med...

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4:39

The Science of Gift Giving

MedEvidence Articles ·

2025/12/22

In this week's episode, which revisits a topic from several years ago, we go deep into the brain to explore what happens inside whe nwe give gifts. We explore a few studies which have looked at brain activity during gifting - including during diffrent types of gifting - and explore why giving gifts makes you feel good, connects you with friends, and acts as a prosocial activity. References: Aknin, L. B., Barrington-Leigh, C. P., Dunn, E. W., Helliwell, J. F., Burns, J., Biswas-Diener, R., ....

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4:59

How to Avoid Holiday Heart Syndrome

MedEvidence Articles ·

2025/12/15

In this episode we explore the less cheery side of the holidays: holiday heart syndrome. This syndrome is defined as irregular heartbeats that occur as a result of binge drinking, the type of which is frequently seen around the holidays. We explore the risks, outcomes, mechanics, and treatments of this not-so-happy heart syndrome. References: Jain, A., Yelamanchili, V. S., Brown, K. N., & Goel, A. (2024). Holiday heart syndrome. In StatPearls [Internet]. StatPearls Publishing. https://w...

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7:17

Gout Isn’t Purely a Problem Of Passing Purine

MedEvidence Articles ·

2025/12/08

In this week's episode, we explore the stream of causes that can lead to the painful inflammatory condition gout. We look at the risks, progression, mechanics, and solutions available for this most common inflammatory arthritis. The primary cause of gout is excessive urate in the the blood depositing itself, especially toes. We then look ahead to clinical trials that recently wrapped up or are currently underway and which target the underlying urate in the blood or the immune response to urat...

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4:33

The Placebo Effect Uses Fake Medicine to Get Real...

MedEvidence Articles ·

2025/12/01

In this week's episode, we talk about placebos, which are inert "medications" used to compare with active drugs. We talk about how the use of medications that "do nothing" can provide pain relief, change hormone balance int he body, and lower symptoms across a broad variety of diseases.

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5:57

Thinking Our Way to Better Health

MedEvidence Articles ·

2025/11/24

In this week's episode, we explore some specific, actionable methods for increasing gratitude. These include gratitude journaling, gratitude letters, mental subtraction, and experiantial consumption. We go over what the methods are, how they work, and how expressing gratitude may help mental health.

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111 results

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