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PODCAST

The Biorevolution Podcast

Louise von Stechow

The Biorevolution Podcast with Andreas Horchler and Louise von Stechow – father and daughter, journalist and biologist, talking about the technologies of the biorevolution. Can genetic engineering, synthetic biology, and artificial intelligence save humanity from disease, climate change, and overpopulation, or are these technologies the first step towards its downfall? Content and Editing: Louise von Stechow and Andreas Horchler Disclaimer: Louise von Stechow, Andreas Horchler and their guests

science life sciences

All Episodes

42:42

Virtual cells - Decoding life's basic units

The Biorevolution Podcast ·

2025/11/07

Cells are the basic units of life. For over a century, understanding cellular processes has been the basis for understanding human development and disease, and for deciphering the actions of novel disease treatments. But there’s a caveat: wet-lab studies in cells take time and money, they are often reductionist. To overcome those challenges of the wet lab, researchers have for some time tried to model cellular processes mathematically, in so-called virtual cells. With the availability of large-scale

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43:31

The 8 Essentials For Overcoming Cancer

The Biorevolution Podcast ·

2025/10/20

Every second man and every third woman will experience a cancer diagnosis during their lives. Getting the news can be devastating and paralyzing, but making the right decisions about treatment, care, mindset and lifestyle is a crucial part of finding a cure.In her book “The 8 Essentials for Overcoming Cancer - Cancer, I can” medical doctor and pharma executive, Stefanie Walther describes her very personal journey and gives holistic advice for battling a cancer diagnosis, from finding the right

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42:03

Creative Matter: Where Art Meets Science

The Biorevolution Podcast ·

2025/10/01

This time Louise and Andreas invited the artist Annette Goessel into the show to discuss the once united forces of art and science that seem so seperate in our day and age. And: For the first time since the beginnings of the show we speak German once more (apologies to the non German speakers) In dieser Episode diskutieren wir die faszinierende Verbindung zwischen Kunst und Wissenschaft. Wir erkunden, wie Neugier und Emotionen sowohl Künstler als auch Wissenschaftler antreiben und welche Rolle der

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29:38

Out of the Lab, Into the Code: An Age of AI Scientists?

The Biorevolution Podcast ·

2025/09/01

It sounds promising: AI chatbots acting as scientists, condensing the work of weeks, months, or even years of reading, debate, and hour-long lab meetings into minutes. Researchers at Stanford University and Google DeepMind have released multi-agent AI “scientist” systems. But how good are they, really, and will they overcome current limitations of large language models like OpenAI’s GPT or Google’s Gemini—such as the lack of robust reasoning capabilities, which are crucial for scientific discovery

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27:41

The biorevolution podcast #37

The Biorevolution Podcast ·

2025/08/01

The $600 billion MedTech industry is undergoing a technological transformation. From AI-powered medical imaging to smart diagnostics and remote monitoring tools, artificial intelligence and machine learning are reshaping how care is delivered — and increasingly how patients manage their own health.In this episode of the BioRevolution podcast, we are joined by our guest, idalab’s MedTech expert Julian Beimes to discuss how this AI-driven wave aligns with broader shifts in medicine: virtualization,

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41:45

The biorevolution podcast #36

The Biorevolution Podcast ·

2025/07/02

Food is a topic that is both deeply personal and of global importance. What we eat affects our health and longevity, but also the lives of animals and the future of our planet.New technologies and scientific discoveries are now enabling us to transform how we produce food and personalize nutrition in entirely new ways. In this episode, Andreas Horchler and Louise von Stechow speak with food expert and CEO of Berlin Food Campus, Lia Carlucci, about key trends shaping the future of food—from

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41:15

The biorevolution podcast #35

The Biorevolution Podcast ·

2025/06/02

Despite great hopes for Artificial Intelligence (AI) in biotech and pharma—with investments exceeding $50 billion over the past ten years—the question of when the technology will reach maturity remains difficult to answer. How can biotech and pharma leaders navigate this complex gray area, where hype around the technology obscures the outlook and few concrete milestones provide clear signposts for decision-making?In this episode of the BioRevolution podcast, Louise von Stechow and Andreas Horchler

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38:11

The biorevolution podcast #34

The Biorevolution Podcast ·

2025/05/05

More than 20 years after the Human Genome Project, enabled by new sequencing technologies, researchers are making progress in exploring the vast non-coding space that constitutes 98% of our genomes. This non-coding, or "dark," DNA harbors elements with important regulatory functions in health and disease. But pinpointing disease-relevant DNA elements within this massive DNA space can be like searching for a needle in a haystack. This difficult search can be eased by artificial intelligence

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42:21

The biorevolution podcast #33

The Biorevolution Podcast ·

2025/04/01

When the Swiss chemist synthesized and tested the psychedelic compound LSD in the 1930s, he knew he had found a tool to explore the human mind.Indeed, before psychedelics became illegal in the late 1960s, a mountain of evidence had been produced, showing potential benefits of psychedelic-assisted therapy for depression, anxiety, and substance abuse. After a decades-long hiatus, research on psychedelics as a treatment for psychiatric diseases is experiencing a renaissance—and initial results look

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39:38

The biorevolution podcast #32

The Biorevolution Podcast ·

2025/03/03

This time on the BioRevolution podcast: science itself.While recent surveys show persistently high trust in science worldwide, certain scientific topics have become the subject of intense societal and political debate. This politicization of science puts scientists in a difficult position when they are trying to argue based on facts. The value of facts and evidence-based science seems to be increasingly questioned by those in power and by those in control of assets. If those who make laws and

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39:42

The biorevolution podcast #31

The Biorevolution Podcast ·

2025/02/03

In some respects, 2024 has been a record year for AI in biotech, with the $1 billion founding of the antibody-centered biotech company Xaira and the awarding of the Nobel Prize in Chemistry to DeepMind researchers Demis Hassabis, John Jumper, and David Baker. However, despite years of investment and innovation, we still lack an answer to the most pressing question: Will AI revolutionize drug development, or are we in a bubble that is about to burst?In episode 30 of the BioRevolution podcast,

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39:19

We're doomed we're saved #30

The Biorevolution Podcast ·

2025/01/03

2025: For millions of people, the new year starts with the self-promise to improve, to quit smoking, alcohol, to get in shape, to stay young and attractive, to basically create and become a new me. While traditionally new year vows meant to relinquish, today there seem to be many helpers in the form of biohacking.Beginning with diets and not ending with technical devices. While there are real shortcuts and fake abbreviations to reach some of those goals, there´s also traditional ways. In "New year

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37:28

We're doomed we're saved #29

The Biorevolution Podcast ·

2024/12/02

Modern humans are stressed creatures: overloaded schedules, constantly “on-call,” and social media haunting us into the late night.Part of this stress is maladaptive responses that date back to human history when stressors were about life and death and not about writing emails and making phone calls. A key player in those ancient responses is cortisol, a stress hormone that interacts with many biological functions, from heart rate to glucose metabolism, to inflammation and immune responses, as well

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39:40

We're doomed we're saved #28

The Biorevolution Podcast ·

2024/11/01

Science can be complex and difficult to grasp, yet public understanding is crucial for navigating issues like disease risk, climate change, and pandemics. Clear, engaging science communication can help prevent misinformation and conspiracy theories, offering facts in place of myths. But how can we make science more digestible and appealing?Counterintuitively, it might be less facts and more emotions that can help to make science more appealing, more impactful – both when communicating to the public

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31:37

We're doomed we're saved #27

The Biorevolution Podcast ·

2024/10/01

In the expensive and failure-prone process of drug development, artificial intelligence (AI) can serve both as an efficiency tool and as a creativity tool. Increased efficiency means shorter timelines, reduced investment, and earlier insights into success or failure. This can lead to more opportunities to bring new drugs to patients. Increased creativity means exploring new areas in drug discovery and development, such as identifying new patterns in targets, drug molecules, and patient populations

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30:52

We're doomed we're saved #26

The Biorevolution Podcast ·

2024/09/02

How will the medicine of the future look? Healthcare and medicine are on the verge of transformative change, driven by new technologies such as artificial intelligence, telemedicine, and wearable devices. Alongside the technologization and virtualization of medicine, there is a shift from reactive "fix the broken" approaches to preventative strategies and from one-size-fits-all treatments to personalized medicine.In this future, human healthcare professionals and machines will work hand-in-hand to

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37:02

We're doomed we're saved #25

The Biorevolution Podcast ·

2024/08/02

Some 36 months after the release of ChatGPT, the verdict is still out on the role that large language models (LLMs) will play in biotech, pharma, and medicine. On paper, the range of tasks that LLMs can perform in biomedical research and healthcare is vast—excavating relevant information for drug discovery from mountains of scientific literature, designing novel proteins, transcribing doctors' notes, aiding diagnostic decision-making, and acting as patient-facing chatbots.But given the models’

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31:38

We are doomed we are saved #24

The Biorevolution Podcast ·

2024/07/02

Rare or orphan diseases affect only a small percentage of the population and often lack effective treatments. While rare individually, in total, more than 350 million people worldwide live with rare diseases. Many of these are very hard to diagnose, let alone cure, and the rarity of patients challenges the development of novel treatments.To make the development of drugs for rare diseases more efficient and successful, artificial intelligence could be an important ally not only for drug makers but

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42:33

We are doomed we are saved #23

The Biorevolution Podcast ·

2024/06/03

When we think about revolutions, we think of systemic changes in politics, economics, and lifestyles. Revolutions transform how we live, work, interact, and communicate. In the past, political uprisings and new technologies, from the steam engine to the smartphone, have led to such transformative changes.Now, a revolution driven by novel biotechnologies (gene editing, neuroprosthetics, synthetic biology, and artificial intelligence in biotech) has the potential to not only change the way we live

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41:25

We are doomed we are saved #22

The Biorevolution Podcast ·

2024/05/03

Polygenic risk scores (PRS), put simply, look at gene variants across the human genome in order to determine an individual's risk of getting a disease, from different types of cancer to type II diabetes. PRS could complement current risk prediction models and lead to a more accurate risk prediction. However, for PRS to become a useful clinical instrument, transparent ways to assess their performance and careful communication of disease risks to individuals are key. In episode 22 of We’re doomed

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41 results

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