科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在《International Journal of Epidemiology》(IF:6.4)上的重要研究"Using Mendelian randomization to investigate etiologic heterogeneity across renal cell carcinoma subtypes"。这项创新性研究利用孟德尔随机化方法，揭示了肾细胞癌不同亚型的独特病因模式。研究发现，肥胖、血压和吸烟等因素与透明细胞肾癌关联更强，而慢性肾病、肾功能指标和端粒长度则与乳头状肾癌关联更显著。这一发现强调了在肾癌研究和临床实践中区分组织学亚型的重要性，为个性化预防和精准治疗提供了关键依据。

People may think of hair loss as a guy thing. But by some estimates, half of all women experience hair loss in their lifetime. And when your social media algorithm gets a whiff? Good. Luck. There are some solutions out there based in science, but not every remedy works for every person — or every type of hair loss. (Yes, there are different types. And the type you have matters!) So today, pharmaceuticals correspondent Sydney Lupkin guest hosts the show to talk about causes of hair loss and how to

في هذه الحلقة، نستكشف المسؤوليات والتكاليف الأساسية لما بعد التسويق للحفاظ على تسجيلات الأجهزة الطبية في المكسيك. نناقش متطلبات COFEPRIS الإلزامية، بما في ذلك أنظمة المراقبة القوية، والإبلاغ عن الأحداث السلبية، وأنشطة اليقظة المستمرة. كما نكشف عن التكاليف السنوية المتوقعة التي تبلغ حوالي 5,000 دولار، والتي تغطي رسوم الممثل المحلي، ومعالجة التعديلات، لضمان استمرار وجود منتجك في السوق دون انقطاع.- ما هي التزامات ما بعد التسويق الإلزامية في المكسيك؟ - كيف يمكن لنظام اليقظة القوي أن يحمي تسجيل

In this thrilling episode, we dive into the extraordinary world of Dr. Chad, a Utah-based physician whose days are spent saving lives and whose nights are dedicated to unraveling the mysteries of the paranormal. By day, Dr. Chad is a compassionate healer, tending to patients with precision and care. By night, he transforms into a relentless ghost hunter, driven by a scientific mind and an insatiable curiosity about the unknown. Once a skeptic, Dr. Chad’s journey into the paranormal has reshap...

This episode covers childhood obesity.Written notes can be found at https://zerotofinals.com/paediatrics/development/childhoodobesity/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

What is the musculovenous pump? How does it help lift all that blood from your legs back up to your heart when you're walking around? Let's talk about the veins and their valves, where they lie in the lower limbs and the deep fascia that surrounds them and the muscles.

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。今天我们关注发表在《Neuro-oncology》(IF: 16.4)上的重要研究"Associations of supramaximal resection with outcome in glioblastoma across age groups: a report of the RANO resect group"。这项国际研究分析了1260例胶质母细胞瘤患者，发现手术切除效果存在年龄差异。虽然完全切除对比增强肿瘤对所有患者都有益，但超最大切除仅在65岁以下初发患者中显著延长生存期(40 vs 20个月)。在复发病例中，最大切除对年轻患者更有利。研究结果支持根据年龄采取分层手术策略，为胶质母细胞瘤的个体化治疗提供了重要依据。

Are some people missing arm muscles? Are there other muscles that we're losing? Can bats and moles actually see? Can the side effects of prostate surgery be reversed? Is there a cure for Dupuytren's contracture? Do we know what long COVID is? What are bluebottle jellies? Can we protect our food from microplastics? Should you get a rabies check after every dog bite? Dr Chris Smith and Saskia Falken have all the answers... Like this podcast? Please help us by supporting the Naked Scientists

On this episode of Unsupervised Learning, Razib talks to Alexander Cortes. Cortes is a trainer, fitness influencer and entrepreneur. He is the co-founder, along with his wife, of Ferta, a company that aims to "optimize your reproductive health and conceive naturally." Born and raised in California, Cortes began his career in the fitness industry as a personal trainer in 2010. Over the next few years he expanded his efforts online, writing about fitness and nutrition from a science-informed

👉 Para receber diretamente os áudios no seu celular, entre para o grupo: 🔗 https://site.vedanta.com.br/lead/cast-jz Saiba mais sobre esse conhecimento em: https://www.instagram.com/vedanta.soma

科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在《International Journal of Molecular Sciences》(IF: 4.9)上的重要研究《HPV-Independent Cervical Cancer-A New Challenge of Modern Oncology》。这项研究揭示了约5-11%的宫颈癌与HPV无关，这类癌症具有独特的分子特征和临床行为，常因诊断延迟而发现于晚期阶段。研究指出，与HPV阳性宫颈癌不同，这类肿瘤表现出TP53、PIK3CA、KRAS等特定突变，导致对传统治疗反应较差。然而，PI3K/mTOR和KRAS抑制剂可能为特定患者带来新希望。这项研究强调了在治疗这种侵袭性宫颈癌中需要精准医疗的重要性，为未来研究和临床实践指明了方向。

Hoe schelpkokerwormen onze kust beschermen, Amsterdammers krijgen 750 bomen cadeau, Tjeerd de Groot over zijn boek 'Politiek is niet voor bange mensen' en herbeleving van de meteorietinslag in de dinotijd. En verder: boer gaat bij Extinction Rebellion, kunstfestival Rewilden, bomen op het dak, dieren spotten op de camera en natuurboeken met Alexander Reeuwijk. De column is deze week van Dolf Jansen. Vroege Vogels Radio op NPO Radio 1 wordt zondag gepresenteerd door Menno Bentveld van 7.00 tot 10.00

تستكشف هذه الحلقة المتطلبات الأساسية لتسجيل الأجهزة الطبية في المكسيك من خلال هيئة COFEPRIS. نناقش المسارين الرئيسيين: مسار المعادلة السريع الذي يعتمد على الموافقات من أسواق مرجعية مثل الولايات المتحدة وأوروبا، والمسار القياسي الذي يتطلب ملفًا فنيًا كاملاً. كما نغطي المتطلبات المشتركة مثل شهادة ISO 13485، والترجمة إلى الإسبانية، والحاجة الماسة لتعيين حامل تسجيل محلي في المكسيك.- ما هي الهيئة التنظيمية المسؤولة عن الأجهزة الطبية في المكسيك؟ - ما الفرق بين مسار المعادلة والمسار القياسي للتسجيل؟ -

TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator SARS-CoV-2 mRNA vaccines sensitize tumors to checkpoint

پادکست هوشیوار – سخنرانی دکتر مهدی شفا 🧠 موضوع: رهایی حیوانات و اخلاق مهربانی بر اساس کتاب Animal Liberation Now اثر پیتر سینگر (۲۰۲۳) در این سخنرانی علمی و فلسفی، دکتر مهدی شفا نگاهی ژرف به اندیشه‌های پیتر سینگر، فیلسوف استرالیایی و بنیان‌گذار اخلاق فایده‌گرای مدرن، می‌اندازد. او با تکیه بر داده‌های عصب‌شناسی، زیست‌شناسی رفتاری و پژوهش‌های محیط‌زیستی، نشان می‌دهد که توانایی رنج کشیدن باید معیار اصلی ارزش اخلاقی باشد — نه گونه، نژاد یا میزان هوش. این سخنرانی ضمن مرور ریشه‌های فلسفی

Dr Tom Russ narrates his blog written for Dementia Researcher.In this guest blog, Tom traces his path into clinical research, crediting the people who guided, inspired, and challenged him along the way. From his early days in psychiatry to leading national dementia research initiatives, he explores the lessons learned from mentors like Professor John Starr and others who shaped his academic and clinical outlook. The piece underscores the importance of supportive working cultures, mentorship, and

What does it really take to build an ASC Sterile Processing department that runs lean and safe? In this premiere episode of our new podcast series "Sterile Horizons," we're joined by longtime industry consultant David Jagrosse to explore the core principles behind ASCs that work smarter—not harder. From eliminating waste to improving team flow and reducing risk, David walks us through what lean design looks like in the fast-paced world of ambulatory surgery. Whether you're planning a new build or

On this week’s episode, Daphne Zohar, Bruce Booth, Sam Fazeli, Brian Skorney, Yaron Werber, and Eric Schmidt kick off with market updates, noting that the XBI is showing signs of a sustainable recovery after years of underperformance and highlighting that the IPO market is likely closed for the remainder of the year, but note optimism for early 2026. In deal news, Novartis’ $12B acquisition of Avidity is spotlighted as an unprecedented move for a company yet to read out Phase 3 data. The co-hosts

We continue our interview with Dave Latorra and Stephanie Ford, the entrepreneurs behind DNA is Love, a unique company that uses science to make cherished memories. Dave describes his science journey as “one thing leading to another.” After high school, he attended junior college where his interest in chemistry first blossomed, then he transitioned to biochemistry followed by microbiology, and ended up pursuing molecular biology during graduate school at Colorado State University. Throughout ...

科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。《Association of Epigenetic Age Acceleration and Mitochondrial DNA-Based Aging Metrics Provides Insights Into Mechanisms of Aging-Related Diseases》这项重要研究发表在影响因子8.0的《Aging cell》期刊上。研究发现，线粒体DNA的异常与表观遗传衰老加速密切相关：罕见异质性变异增多和线粒体DNA拷贝数减少都会加速表观遗传衰老，尤其在老年人中更为明显。更引人注目的是，表观遗传衰老指标介导了线粒体DNA拷贝数与肥胖、2型糖尿病之间的关联。这一发现为理解衰老相关疾病的机制提供了新视角，也为开发针对性干预措施奠定了基础。