科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注最新发表在《Cancer》(影响因子6.1)上的重要研究"A tour of leukemia progress in 2025, viewed through the MD Anderson leukemia research lens"。这项回顾性研究揭示了白血病治疗的革命性进展，过去20年靶向治疗彻底改变了治疗格局。从blinatumomab等抗体药物到BCR::ABL1抑制剂等小分子靶向药，不仅提高了患者生存率，还减少了对传统化疗的依赖。研究显示，更多白血病类型现被归类为"有利型"，包括慢性淋巴细胞白血病和特定急性淋巴细胞白血病亚型。然而，对于TP53突变等高风险患者群体，仍需开发更有效的治疗方案。这项进展为临床医生提供了宝贵的治疗参考，也为未来研究指明了方向。

Vamos falar da importância de se respirar pelo nariz e respirar devagar. Ciclos de 5,5s de inspiração e 5,5s de expiração. Técnicas extraída do livro "Respire: a nova ciência de uma arte perdida" de James Nestor, que recomendo a leitura para aprofundamento.https://www.mrjamesnestor.com/

[HæmatoLOGIK er henvendt til sundhedsfagligt personale]Hvad er bedst til patienter med tidligere ubehandlet CLL?1)  Kombinationsbehandling med akalabrutinib og venetoclax2) Kombinationsbehandling med akalabrutinib, venetoclax OG obinutuzumab, eller3) klassisk kemoimmunterapi?Det er netop spørgsmålet dine to Aarhus-værter dykker ned i, når de gennemgår det internationale AMPLIFY-studie fra 2025. Resultaterne viser markante forskelle i effekt, bivirkninger og overlevelse – og giver nye perspektiver

Some scientists looking to preserve vulnerable species have turned to a controversial technique: synthetic biology. This catchall term often means genetic engineering – introducing new genes to an organism. And a recent narrow vote by the International Union for Conservation of Nature on using the technology shows how divided scientists are on the issue of releasing genetically altered species. Science correspondent Nate Rott wades into the debate with us and reveals whether or not the Union voted

"Snalaženje" je riječ koju svako u Bosni i Hercegovini i regionu odmah razumije. To nije samo riječ, to je koncept i način života. Ona rijetko znači "poštovati pravila" i gotovo uvijek znači "naći način da se pravila zaobiđu".Snaći se na ovim prostorima, obično znači samo jedno.Klikni i podrži ovaj podcast.

Tilstrekkelig vannbehandling er et veldig viktig biosikkerhetstiltak for å hindre spredning av smittestoffer i akvakulturen. Men hvordan sikrer vi trygt vann i en stadig mer kompleks akvakulturnæring?Dagens vannbehandlingsregler stammer fra 1990-tallet, og mye har skjedd i næringen siden den gang. Nye produksjonsformer, høyere biosikkerhetskrav og økende sykdomspress gjør at gamle rutiner ikke alltid strekker til.I denne episoden av VETpodden utforsker vi behovet for bedre kontroll av

في هذه الحلقة، نغوص في عالم ما بعد الحصول على الموافقة التنظيمية، ونستكشف المتطلبات الإلزامية لمراقبة ما بعد التسويق (PMS) للأجهزة الطبية. نناقش لماذا تعتبر هذه العملية المستمرة حاسمة لجميع فئات الأجهزة، وما هي الأنشطة التي تتضمنها، ونكشف عن التكاليف السنوية المرتبطة بها لضمان بقاء منتجك في السوق بشكل آمن ومتوافق.- ما هي مراقبة ما بعد التسويق (PMS) ولماذا هي إلزامية؟ - هل تنطبق هذه المتطلبات على جميع فئات الأجهزة الطبية؟ - ما هي الأنشطة التي تتضمنها عملية المراقبة المستمرة؟ - كم تبلغ التكلفة

In this podcast, we provide a summary of the scientific consensus on Menopause and highlight resources for women looking to understand how they can address the multifaceted challenges and management strategies associated with the menopausal transition, focusing on both the physical and psychosocial impacts. A significant theme is the importance of lifestyle medicine, advocating for prescriptive resistance exercise to combat bone and muscle loss (osteoporosis and sarcopenia) and targeted

In this episode of The Dairy Health Blackbelt Podcast, Dr. Guillermo Martinez-Boggio from the University of California, Davis, explores the role of genetics in improving feed efficiency and reducing methane emissions in dairy cows. He explains how genomic tools and reference populations are being developed to help farmers select more efficient, lower-emission animals. Learn how genetics, management, and feeding strategies can work together for a more sustainable dairy industry. Listen now on all

The blood-brain barrier (BBB), formed by brain endothelial cells, pericytes, and astrocytes, is organized into a neurovascular unit that regulates the exchange of proteins between blood circulation and brain parenchyma. Human stem-cell-based models using brain endothelial cells are a powerful tool to investigate how disease-related conditions might affect the blood-brain barrier integrity. However, the cell type composition is critical to faithfully model transcytosis across the blood-brain b...

As cancer research progresses rapidly, obtaining high-quality biospecimens has grown increasingly important for making significant breakthroughs.In this CrownCast episode, Rajendra Kumari, Executive Director of Integrated Solutions at Crown Bioscience, talks with Sadaf Malik, Senior Director, Head US Sales (Biobank and Biomarker) about how superior biospecimens can drive advancements in oncology by means of innovative biobanking.

Diabetes technology is evolving fast. In ATTD Tech Connect, we show how it can help healthcare professionals — nurses, educators, and dieticians — improve therapy and daily life for people living with diabetes.In this new series sponsored by Medtronic Diabetes, you’ll learn from diverse clinical experience and evidence-based guidance from leaders in diabetes care, tailored for those who support patients every day.Hosted by Julie Taplin, Dietician and Medtronic Diabetes Education Specialist, the

In this captivating episode, we’re thrilled to welcome acclaimed director, producer, and writer Joseph Granda, renowned for his inspiring films The Healing Garden and A Walk in the Clouds. Today, Joseph joins us to discuss his exhilarating new project, the award-winning The Sasqualogist, a cinematic adventure sure to captivate audiences, especially Bigfoot enthusiasts. He also shares fascinating insights into another film he produced, Sasquatch and the Missing Man, where he and his team encou...

43. Tema: Gamla surdegar och ny energi - hur inre städning kan skapa lugn. Gäst: Mia SonnelidBeskrivning: Jenny pratar med cert. handledare i sorgbearbetning Mia Sonnelid om sorg och hur det uttrycks i förlust och förändring. Mia berättar om metoden och olika delar. Alltför många försöker förstå sorg på ett intellektuellt plan men behöver möta sig själva i känslorna. Obearbetad sorg kan resultera i isolering, surdegar, blockeringar och smärta och därmed påverka oss i våra dagliga liv på olika

️ Episode 182: Genotypic, Functional, and Phenotypic Characterization in CTNNB1 Neurodevelopmental Syndrome In this episode of PaperCast Base by Base, we explore a large cross-sectional cohort study that integrates genetics, cellular functional assays, and deep phenotyping to map the landscape of CTNNB1 neurodevelopmental syndrome. The authors analyze variant types across 127 individuals from 20 countries, probe Wnt/β-catenin signaling consequences in

What happens when three ABA leaders turn their vision into a movement?Jeron Trotman, Joseph Adams, and Darius Cooper open up about how they built Beyond the Science into one of the most impactful voices in behavior analysis. They share the highs of launching new ventures, from group homes to Sapphire AI, and the hidden struggles that come with success: family sacrifices, shifting friendships, and staying grounded while leading a growing community.🎧 Watch now their honest, inspiring look at

In this episode of MedTech Global Insights, we dissect the FDA's groundbreaking final guidance on Predetermined Change Control Plans (PCCPs) for AI/ML-enabled medical devices. We explore how this new framework moves beyond the traditional, rigid regulatory submission process, creating a streamlined pathway for manufacturers to innovate and improve their smart devices safely and effectively.Discover how a PCCP can unlock the full potential of your adaptive medical software. We'll use the example of

In this episode of Center of Excellence – Pharma 4.0, we shift the focus from technology to people — exploring how the pharmaceutical industry is empowering its workforce for success in the digital age.From digital literacy to AI mastery, from immersive learning to innovation leadership, this episode uncovers how pharma organizations are developing the skills, mindsets, and cultural foundations needed to thrive in the Fourth Industrial Revolution. We discuss: Core digital competencies for the

The femoral triangle is an anatomical region in the upper anterior thigh bordered by the inguinal ligament, sartorius muscle and adductor longus muscle. In here we find the femoral nerve, femoral artery and femoral vein with some lymph nodes. These large blood vessels can be used to access vascular structures in the lower limb and torso, including the heart.

Novartis’ biggest deal in more than a decade gives the Swiss pharma three programs for muscular dystrophies that are close to the finish line. On the latest BioCentury This Week podcast, BioCentury’s analysts discuss the $12 billion deal for Avidity in the context of Novartis’ recent acquisitions and the antibody-oligonucleotide conjugate platform it is gaining. The team dives into RNA versus DNA modalities, noting antisense and siRNA approaches appear to be gaining traction with major pharma...